Methotrexate



Combined with:

Asa

Indications and Reactions:

Role Indications Reactions
Primary
Rheumatoid Arthritis 38.1%
Acute Lymphocytic Leukaemia 19.2%
Bone Sarcoma 5.1%
Product Used For Unknown Indication 4.9%
Psoriasis 4.4%
Psoriatic Arthropathy 3.7%
Non-hodgkin's Lymphoma 2.9%
Prophylaxis Against Graft Versus Host Disease 2.5%
B Precursor Type Acute Leukaemia 2.2%
Acute Promyelocytic Leukaemia 2.1%
Breast Cancer 2.0%
Central Nervous System Lymphoma 1.9%
Drug Use For Unknown Indication 1.8%
Juvenile Arthritis 1.8%
Arthritis 1.5%
Burkitt's Lymphoma 1.5%
Acute Myeloid Leukaemia 1.2%
Crohn's Disease 1.2%
Chemotherapy 1.1%
Prophylaxis 1.1%
Vomiting 12.7%
Sepsis 7.7%
Neurotoxicity 6.8%
Stomatitis 6.6%
Toxicity To Various Agents 5.6%
Pancytopenia 5.6%
Thrombocytopenia 5.6%
Renal Failure Acute 5.4%
Weight Decreased 5.1%
Renal Failure 4.9%
Pyrexia 4.8%
Pneumonia 4.2%
Medication Error 4.0%
Drug Ineffective 3.8%
White Blood Cell Count Decreased 3.6%
Respiratory Failure 2.9%
Septic Shock 2.8%
Lymphoproliferative Disorder 2.7%
Breast Cancer 2.6%
Glioma 2.6%
Secondary
Rheumatoid Arthritis 36.0%
Acute Lymphocytic Leukaemia 17.4%
Product Used For Unknown Indication 10.3%
Drug Use For Unknown Indication 6.6%
Prophylaxis 4.7%
Burkitt's Lymphoma 4.2%
Diffuse Large B-cell Lymphoma 2.4%
Psoriatic Arthropathy 2.0%
Non-hodgkin's Lymphoma 1.9%
Hypertension 1.7%
Prophylaxis Against Graft Versus Host Disease 1.6%
Breast Cancer 1.5%
Mantle Cell Lymphoma 1.5%
Psoriasis 1.4%
Chromosome Analysis Abnormal 1.3%
Lymphoma 1.2%
Crohn's Disease 1.2%
Osteoporosis 1.1%
Burkitt's Leukaemia 1.1%
B Precursor Type Acute Leukaemia 1.1%
Sepsis 11.5%
Vomiting 9.5%
Pneumonia 9.2%
Pyrexia 6.5%
Pneumocystis Jiroveci Pneumonia 5.9%
White Blood Cell Count Decreased 5.4%
Thrombocytopenia 5.0%
Off Label Use 4.5%
Lung Neoplasm 4.3%
Weight Decreased 4.2%
Lymphoma 3.9%
Interstitial Lung Disease 3.9%
Septic Shock 3.7%
Neutropenia 3.5%
Rheumatoid Arthritis 3.4%
Respiratory Failure 3.4%
Stomatitis 3.3%
Urinary Tract Infection 3.0%
Death 2.9%
Pulmonary Embolism 2.9%
Concomitant
Rheumatoid Arthritis 37.7%
Product Used For Unknown Indication 21.1%
Drug Use For Unknown Indication 12.5%
Psoriatic Arthropathy 3.9%
Hypertension 3.0%
Prophylaxis 2.6%
Pain 2.1%
Psoriasis 2.1%
Prophylaxis Against Graft Versus Host Disease 2.0%
Crohn's Disease 1.9%
Vitamin Supplementation 1.6%
Osteoporosis 1.5%
Ankylosing Spondylitis 1.1%
Infection Prophylaxis 1.1%
Arthritis 1.0%
Depression 1.0%
Bone Marrow Conditioning Regimen 1.0%
Juvenile Arthritis 0.9%
Diabetes Mellitus 0.9%
Premedication 0.8%
Injection Site Pain 17.0%
Rheumatoid Arthritis 11.1%
Vomiting 6.7%
Drug Ineffective 5.8%
Pain In Extremity 5.0%
Sinusitis 4.7%
Pain 4.6%
Pyrexia 4.6%
Pneumonia 4.4%
Weight Decreased 4.2%
Urinary Tract Infection 3.9%
Injection Site Swelling 3.9%
Nasopharyngitis 3.3%
Weight Increased 3.3%
Nausea 3.2%
Injection Site Reaction 3.2%
Rash 2.9%
Psoriasis 2.9%
Sepsis 2.7%
Headache 2.6%
Interacting
Rheumatoid Arthritis 22.6%
Product Used For Unknown Indication 14.7%
Breast Cancer 9.2%
Drug Use For Unknown Indication 7.3%
Osteoporosis 6.6%
Non-hodgkin's Lymphoma 4.7%
Infection 4.6%
Acute Lymphocytic Leukaemia 4.2%
Hypertension 2.9%
Nasopharyngitis 2.8%
Antifungal Prophylaxis 2.6%
Metastasis 2.5%
Psoriatic Arthropathy 2.4%
Psoriasis 2.2%
Bone Sarcoma 1.9%
Ill-defined Disorder 1.9%
Spindle Cell Sarcoma 1.9%
Acute Myeloid Leukaemia 1.8%
Gastritis 1.6%
Precursor T-lymphoblastic Lymphoma/leukaemia 1.5%
Renal Failure Acute 14.3%
Drug Interaction 12.8%
Vomiting 10.7%
Photosensitivity Reaction 8.2%
Osteonecrosis 4.6%
Rhinorrhoea 4.6%
Mucosal Inflammation 4.1%
Neutropenia 4.1%
Pancytopenia 4.1%
White Blood Cell Count Decreased 4.1%
Haemoglobin Decreased 3.6%
Renal Failure 3.6%
Sepsis 3.6%
Rash Macular 3.1%
Weight Decreased 3.1%
Pneumonia Legionella 2.6%
Pneumonitis 2.6%
Toxicity To Various Agents 2.6%
Acute Prerenal Failure 2.0%
Blood Creatinine Increased 2.0%