Methotrexate combined with Radiation Therapy

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Related Secondary Malignancy Other Serious 62 Female 1/5/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Disability 10/3/2005 38 Female 2/9/2006 Other Health Professional France
Primary
Secondary
Drug Exposure During Pregnancy Disability 10/3/2005 38 Female 2/15/2006 Other Health Professional France
Primary
Secondary
Treatment Related Secondary Malignancy Death 3/1/2005 42 Female 3/28/2006 Consumer United States
Primary
Concomitant
Petechiae Hospitalization 6/8/2002 63 Female 5/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 2 Male 6/29/2006 United States
Primary
Concomitant
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 14 Male 8/3/2006 Consumer United States
Primary
Secondary
Pneumonia Life Threatening 11/30/2005 61 Female 6/6/2006 Physician United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 73 Female 3/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Uv Light Therapy Other Serious 49 Male 3/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Recall Phenomenon 49 Male 3/15/2007 United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Hospitalization 56 Female 6/6/2003 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 52 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
Spinal Cord Disorder Other Serious 25 Male 4/4/2007 Other Health Professional Australia
Primary
Secondary
Spinal Cord Disorder Other Serious 25 Male 4/10/2007 Other Health Professional Australia
Primary
Secondary
Spinal Cord Disorder Hospitalization 25 Male 4/11/2007 Australia
Primary
Secondary
Spinal Cord Disorder Other Serious 25 Male 4/13/2007 Consumer United States
Primary
Secondary
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 55 Female 5/25/2007 Physician Canada
Primary
Secondary
Concomitant
Pleural Fibrosis Disability 2/1/1994 29 Male 79 lb 6/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Fibrosis Disability 2/1/1994 29 Male 79 lb 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 5 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 20 Male 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 11/12/1993 60 Female 10/19/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Myelopathy Other Serious 11/12/2004 60 Female 11/8/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Cerebral Toxoplasmosis Other Serious 52 Male 11/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/1/2004 Male 11/21/2007 Other Health Professional United States
Primary
Secondary
Glioblastoma Multiforme Other Serious 11 Male 11/26/2007 Other Health Professional India
Primary
Secondary
Glioblastoma Multiforme Other Serious 2 Male 11/26/2007 Other Health Professional United States
Primary
Secondary
Wound Infection 2/1/2006 Female 12/8/2007 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2007 28 Female 12/10/2007 Consumer Japan
Primary
Secondary
Testis Cancer Other Serious 30 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Viith Nerve Paralysis Other Serious 39 Female 12/28/2007 Other Health Professional Japan
Primary
Secondary
Nocardiosis Other Serious 17 Male 3/27/2008 Other Health Professional Japan
Primary
Secondary
Tooth Extraction Other Serious 12/12/2000 42 Female 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 13 Female 4/14/2008 Other Health Professional Germany
Primary
Secondary
Graft Versus Host Disease Other Serious 8 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Herpes Zoster Other Serious 11 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Neutropenia Other Serious 11 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Graft Versus Host Disease Other Serious 15 Female 4/15/2008 Other Health Professional Germany
Primary
Secondary
Malignant Neoplasm Progression Other Serious 11 Female 4/15/2008 Other Health Professional Germany
Primary
Secondary
Haemorrhage Intracranial Other Serious 18 Male 4/15/2008 Other Health Professional Germany
Primary
Secondary
Hyponatraemia Other Serious 19 Female 6/4/2008 Other Health Professional United States
Primary
Secondary
Hyponatraemia Other Serious 19 Female 6/6/2008 Other Health Professional United States
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/30/2008 Consumer United States
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/9/2008 Consumer United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/17/2008 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 20 Male 7/30/2008 Other Health Professional United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 23 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 41 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 39 Female 8/5/2008 Other Health Professional United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 23 Male 8/13/2008 Other Health Professional United States
Primary
Secondary
Burkitt's Lymphoma Hospitalization 1/1/2008 66 Male 11/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Burkitt's Lymphoma Other Serious 1/1/2008 68 Male 11/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Life Threatening 10/3/2008 Female 131 lb 11/28/2008 Physician Germany
Primary
Secondary
Neuropathy Peripheral Other Serious 15 Male 12/29/2008 Other Health Professional United States
Primary
Secondary
Post Procedural Complication Required Intervention 8/1/2004 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 2/2/2009 Other Health Professional Austria
Primary
Secondary
Neurofibroma Hospitalization 17 Female 4/23/2009 Other Health Professional Japan
Primary
Secondary
Renal Failure Chronic Other Serious 8/1/2008 14 Male 7/20/2009 Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 8/1/2008 14 Male 8/14/2009 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/11/2001 Female 9/17/2009 Physician United States
Primary
Secondary
Concomitant
Rash Life Threatening 2/27/2009 57 Male 126 lb 10/26/2009 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious Male 1/4/2010 Other Health Professional Australia
Primary
Secondary
Myelitis Transverse Other Serious 17 Female 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 17 Male 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 15 Male 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 6 Male 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 14 Female 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 13 Female 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 16 Male 1/7/2010 Other Health Professional United States
Primary
Secondary
Myelitis Transverse Other Serious 13 Female 1/7/2010 Other Health Professional United States
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 54 Male 1/8/2010 Consumer United Kingdom
Primary
Secondary
Leukoencephalopathy Other Serious 8 Male 1/14/2010 Other Health Professional Australia
Primary
Secondary
Weight Increased Other Serious 7/30/2003 Female 1/15/2010 Other Health Professional United States
Primary
Concomitant
Rash Generalised Life Threatening 4/1/2008 55 Male 126 lb 1/22/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/1/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/5/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/26/2010 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/26/2010 Physician United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/14/2005 Female 127 lb 3/12/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 3/17/2010 Pharmacist United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/27/2004 Female 3/26/2010 Physician United States
Primary
Concomitant
Sudden Hearing Loss Other Serious 10 Male 4/5/2010 Consumer Switzerland
Primary
Secondary
Weight Decreased Other Serious 4/11/2001 54 Female 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/20/2010 United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 4/20/2010 Pharmacist United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 4/21/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 5/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 5/10/2010 United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/19/2010 United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/28/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 6/2/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 6/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/15/2010 United States
Primary
Concomitant
Sinusitis Hospitalization 4/24/2008 51 Female 6/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Vena Cava Filter Insertion Other Serious 4/26/2009 23 Male 225 lb 6/22/2010 Other Health Professional United States
Primary
Concomitant
Vena Cava Filter Insertion Other Serious 4/26/2009 23 Male 225 lb 6/30/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 11/27/2004 46 Female 7/8/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 65 Female 7/23/2010 Other Health Professional Japan
Primary
Secondary
Weight Decreased Other Serious 4/11/2001 54 Female 7/26/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 9/13/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 10/4/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 10/20/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 4/11/2001 54 Female 10/29/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 11/9/2010 Pharmacist United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 11/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2001 62 Female 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/2001 62 Female 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anticoagulation Drug Level Below Therapeutic Hospitalization 7/30/2003 48 Female 2/11/2011 Pharmacist United States
Primary
Concomitant
Bronchitis Other Serious 7/9/2008 50 Female 2/16/2011 Physician United States
Primary
Concomitant
Insomnia Hospitalization 7/30/2003 48 Female 2/23/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Hospitalization 7/9/2008 50 Female 3/22/2011 Physician United States
Primary
Concomitant
Metastases To Meninges Other Serious 1/1/2004 3/25/2011 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2001 62 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atelectasis Other Serious 1/1/2004 48 Female 4/7/2011 Physician United States
Primary
Concomitant
Arthropathy Other Serious 1/1/2004 48 Female 4/27/2011 Pharmacist United States
Primary
Concomitant
Lung Disorder Death 7/9/2008 50 Female 6/6/2011 Lawyer United States
Primary
Concomitant
Lung Disorder Hospitalization 7/9/2008 50 Female 6/13/2011 Lawyer United States
Primary
Concomitant
Urinary Incontinence Death 7/9/2008 50 Female 6/20/2011 Physician United States
Primary
Concomitant
Fibrocystic Breast Disease Other Serious 12/12/2000 47 Female 7/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Phlebolith Other Serious 12/12/2000 47 Female 7/27/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 1/1/2001 62 Female 8/10/2011 Lawyer United States
Primary
Secondary
Concomitant
Intestinal Polyp Other Serious 1/1/2004 48 Female 8/11/2011 Pharmacist United States
Primary
Concomitant
Insomnia Other Serious 4/11/2001 54 Female 8/23/2011 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 12/12/2000 47 Female 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 12/12/2000 47 Female 12/27/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/9/2008 50 Female 1/4/2012 Lawyer United States
Primary
Concomitant
Bacteraemia Other Serious 6/21/2007 50 Female 103 lb 1/11/2012 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/12/2000 47 Female 2/16/2012 Consumer United States
Primary
Secondary
Concomitant
Decubitus Ulcer Hospitalization 12/12/2000 47 Female 3/6/2012 Physician United States
Primary
Secondary
Concomitant
Oral Disorder Other Serious 12/12/2000 47 Female 3/27/2012 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 30 Female 3/30/2012 Other Health Professional Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 10/28/2008 30 Female 4/11/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Oral Disorder Other Serious 12/12/2000 47 Female 4/24/2012 Physician United States
Primary
Secondary
Concomitant
Autoimmune Hepatitis Other Serious 56 Female 5/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Female 5/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Cataract Other Serious 67 Female 6/19/2012 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data