Clarithromycin combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Herpes Zoster Other Serious 1/1/2005 Female 120 lb 1/9/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 8/1/2005 Female 139 lb 1/19/2006 Belgium
Primary
Concomitant
Tuberculosis Other Serious 8/1/2005 Female 139 lb 2/13/2006 Physician Belgium
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 62 Female 7/6/2006
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 62 Female 7/17/2006 Germany
Primary
Secondary
Concomitant
Infection Hospitalization 7/21/2002 64 Female 7/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 75 Female 171 lb 12/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 75 Female 171 lb 11/29/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/3/2005 71 Female 88 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/3/2005 71 Female 88 lb 2/1/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Death Death Female 101 lb 4/11/2007 Physician Japan
Primary
Concomitant
Arthritis Bacterial Hospitalization 2/16/2007 Female 104 lb 4/17/2007 Physician Japan
Primary
Concomitant
Alopecia 8/1/2007 Female 170 lb 12/14/2007 Physician United States
Primary
Concomitant
Pseudoaldosteronism Hospitalization 1/1/2005 53 Female 12/20/2007 Physician Japan
Primary
Secondary
Pyrexia Hospitalization 53 Female 12/20/2007 Japan
Primary
Secondary
Concomitant
Viral Infection Other Serious 12/9/2004 Female 141 lb 1/2/2008 Physician United States
Primary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/31/2008 71 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 1/31/2008 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 3/31/2008 Pharmacist United States
Primary
Concomitant
Tuberculosis Hospitalization 70 Male 6/25/2008
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Troponin Increased Hospitalization 9/12/2005 Male 8/26/2008 Physician France
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 9/12/2005 Male 9/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Shock Death 4/8/2008 17 Male 9/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Superinfection Hospitalization 69 Male 9/17/2008
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/18/2008 Male 57 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Pneumonia Other Serious 7/22/2008 56 Female 11/5/2008 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/17/2008 69 Male 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/22/2008 56 Female 11/25/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2005 80 Female 77 lb 1/5/2009
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2005 80 Female 77 lb 1/5/2009
Primary
Secondary
Concomitant
Urinary Retention Hospitalization Male 2/23/2009 Other Health Professional
Primary
Concomitant
Productive Cough Other Serious 1/6/2009 115 lb 3/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/10/2009 United Kingdom
Primary
Concomitant
Productive Cough Other Serious 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 49 Male 5/11/2009 Other Health Professional Denmark
Primary
Secondary
Renal Failure Hospitalization 49 Male 5/18/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vitamin D Decreased Other Serious 49 Male 5/18/2009
Primary
Secondary
Concomitant
Vomiting Hospitalization 49 Male 5/18/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 6/26/2009 Female 90 lb 8/21/2009 Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/26/2009 Female 90 lb 8/26/2009 Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/26/2009 Female 90 lb 9/11/2009 Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 10/21/2009 30 Female 11/10/2009 Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2009 Female 150 lb 11/18/2009 Canada
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 49 Male 11/20/2009 Other Health Professional Denmark
Primary
Concomitant
Purulent Discharge Hospitalization 10/21/2009 30 Female 11/25/2009 Other Health Professional Japan
Primary
Concomitant
Swelling Hospitalization 10/21/2009 30 Female 12/1/2009 Japan
Primary
Concomitant
Swelling Hospitalization 10/21/2009 Female 12/12/2009 Japan
Primary
Concomitant
Swelling Hospitalization 10/21/2009 Female 12/30/2009 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/21/2009 Female 1/19/2010 Japan
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 3/10/2010 37 Female 3/23/2010 Pharmacist Germany
Primary
Concomitant
Vision Blurred Other Serious 1/19/2010 60 Female 168 lb 3/25/2010 Pharmacist
Primary
Concomitant
Vision Blurred Other Serious 1/19/2010 60 Female 168 lb 3/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 1/19/2010 60 Female 168 lb 3/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 1/19/2010 60 Female 168 lb 3/31/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Sarcoidosis Other Serious 1/1/2005 30 Female 4/5/2010
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/19/2010 60 Female 4/2/2010 United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 3/10/2010 37 Female 4/19/2010 Pharmacist Germany
Primary
Concomitant
Withdrawal Syndrome Other Serious 3/1/2010 37 Female 148 lb 4/30/2010 Germany
Primary
Concomitant
Interacting
Platelet Count Decreased Hospitalization 3/31/2009 83 Female 110 lb 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/1/2009 70 Male 121 lb 7/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 6/25/2010 Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 7/14/2010 Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 7/19/2010 Japan
Primary
Concomitant
Surgery Death 4/14/2010 54 Male 128 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 33 Male 8/6/2010 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 82 Female 187 lb 8/23/2010 Consumer Brazil
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 82 Female 187 lb 8/26/2010 Consumer Brazil
Primary
Concomitant
Sicca Syndrome Other Serious 8/31/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sicca Syndrome Other Serious 7/1/2009 48 Male 9/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sicca Syndrome Other Serious 7/1/2009 48 Male 9/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Synovial Rupture Other Serious 11/1/2009 79 Male 10/18/2010 Physician United Kingdom
Primary
Concomitant
Gastric Cancer Other Serious 7/21/2010 75 Male 137 lb 11/8/2010 Physician Japan
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 3/1/2010 37 Female 148 lb 4/30/2010 Germany
Primary
Concomitant
Interacting
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 12/17/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 7/21/2010 75 Male 137 lb 1/12/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/1/2009 79 Male 1/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Rupture Hospitalization 3/31/2009 83 Female 110 lb 2/3/2011 Physician Japan
Primary
Secondary
Concomitant
Orthopedic Procedure Hospitalization 2/7/2011 66 Female 104 lb 3/28/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Bronchiectasis Hospitalization 35 Male 3/30/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Other Serious 11/7/2010 77 Female 4/1/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 9/9/2009 36 Female 125 lb 3/31/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 9/9/2009 36 Female 125 lb 4/7/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/7/2010 78 Female 104 lb 4/15/2011 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 3/14/2011 54 Female 150 lb 4/11/2011 Consumer Canada
Primary
Concomitant
Skin Disorder Hospitalization 1/1/2007 60 Female 160 lb 5/5/2011 Consumer United States
Primary
Concomitant
Bronchopneumonia Hospitalization 4/21/2011 50 Female 5/4/2011 Other Health Professional Japan
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 4/1/2011 58 Female 106 lb 5/10/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Subdural Haematoma Hospitalization 11/7/2010 78 Female 104 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 3/30/2011 50 Female 4/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/22/2010 59 Male 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 11/7/2010 78 Female 104 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/7/2010 78 Female 104 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 3/30/2011 50 Female 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 48 Male 5/27/2011 Other Health Professional Japan
Primary
Secondary
Tuberculosis Other Serious 4/14/2011 58 Female 106 lb 6/1/2011 Physician Korea, Republic Of
Primary
Concomitant
Myocardial Infarction Hospitalization 3/22/2010 59 Male 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 4/21/2011 50 Female 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 11/7/2010 78 Female 104 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 11/11/2008 76 Female 104 lb 6/15/2011 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/22/2010 59 Male 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 11/7/2010 78 Female 104 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 11/7/2010 78 Female 104 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/7/2010 78 Female 104 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 97 lb 7/18/2011 Other Health Professional Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 11/7/2010 78 Female 104 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 6/18/2010 39 Female 110 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/24/2011 72 Male 116 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2011 72 Female 8/12/2011 Consumer Japan
Primary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Atypical Mycobacterial Infection Other Serious 8/1/2010 54 Female 99 lb 8/18/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 106 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Death 11/17/2009 6 Male 33 lb 9/19/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/19/2009 10 Male 49 lb 9/19/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2011 67 Female 106 lb 11/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 6/21/2011 72 Male 116 lb 11/30/2011 Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 12/7/2009 21 Male 132 lb 12/1/2011 Physician Japan
Primary
Concomitant
Uterine Cancer Hospitalization 12/21/2009 47 Female 99 lb 12/19/2011 Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 7/6/2011 72 Female 99 lb 12/19/2011 Consumer Japan
Primary
Concomitant
Haemolytic Anaemia Life Threatening 11/17/2009 6 Male 33 lb 12/30/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 3/11/2009 9 Male 49 lb 12/30/2011 Physician Japan
Primary
Concomitant
Lung Infection Pseudomonal Life Threatening 6/1/2011 65 Female 88 lb 1/3/2012 Physician Japan
Primary
Concomitant
Cholestasis Hospitalization 12/29/2011 75 Female 1/25/2012 Physician Italy
Primary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 88 lb 1/26/2012 Japan
Primary
Concomitant
Headache Other Serious 12/1/2010 45 Male 185 lb 1/28/2012 Physician United States
Primary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 88 lb 2/1/2012 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 6/8/2009 6 Male 33 lb 2/9/2012 Physician Japan
Primary
Concomitant
Post Transplant Lymphoproliferative Disorder Death 3/6/2009 9 Male 49 lb 2/10/2012 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 6/18/2010 39 Female 110 lb 2/15/2012 Physician Japan
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 59 Male 106 lb 2/16/2012 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Conjunctival Hyperaemia Other Serious 7 Female 2/17/2012 Other Health Professional Canada
Primary
Secondary
Acute Graft Versus Host Disease In Skin Death 3/6/2009 9 Male 49 lb 3/9/2012 Physician Japan
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 6/8/2009 6 Male 33 lb 3/9/2012 Physician Japan
Primary
Concomitant
Psychotic Disorder Hospitalization 2/3/2012 61 Male 3/7/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 5/13/2010 Male 20 lb 3/13/2012 Physician Japan
Primary
Secondary
Concomitant
Genital Abscess Other Serious 9/1/2011 48 Female 3/21/2012 Other Health Professional Colombia
Primary
Concomitant
Cough Death 74 Male 3/22/2012 Other Health Professional Switzerland
Primary
Concomitant

Drug Data