Methotrexate combined with Methylprednisolone Sodium Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Varicella Hospitalization 12/30/2005 4 Male 40 lb 4/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Condition Aggravated Other Serious Male 32 lb 1/18/2007 Consumer Canada
Primary
Concomitant
Nonspecific Reaction Other Serious 52 Female 137 lb 12/26/2007 Physician Poland
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 12/21/2007 46 Male 157 lb 1/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Resorption Bone Increased Hospitalization 2/9/2007 Male 160 lb 9/11/2008 United States
Primary
Concomitant
Uterine Hypertonus Hospitalization 8/12/2006 Female 155 lb 12/10/2008 United States
Primary
Concomitant
Pneumoperitoneum Hospitalization 53 Female 12/30/2008 France
Primary
Secondary
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumoperitoneum Hospitalization 53 Female 1/8/2009 France
Primary
Secondary
Thrombotic Microangiopathy Other Serious 59 Male 4/6/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 57 Female 4/22/2009 Pharmacist Japan
Primary
Concomitant
Vomiting Other Serious 57 Female 5/1/2009 Pharmacist Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 59 Male 5/11/2009 Physician Japan
Primary
Concomitant
Swelling Face Other Serious 8/26/2008 18 Female 201 lb 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 2/1/2009 12 Male 12/2/2009 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/8/2009 58 Female 106 lb 12/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Death 55 Male 12/22/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 8 Female 12/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Mycosis Life Threatening 5/26/2009 20 Female 2/1/2010 Physician Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/30/2009 Male 2/1/2010 Physician Italy
Primary
Secondary
Pulmonary Mycosis Life Threatening 5/26/2009 20 Female 2/3/2010 Physician Italy
Primary
Secondary
Concomitant
Asphyxia Death 6/27/2009 Female 2/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2009 64 Female 123 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Asphyxia Death 6/27/2009 Female 2/23/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Pulmonary Mycosis Life Threatening 5/26/2009 Female 3/4/2010 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Mycosis Life Threatening 5/26/2009 20 Female 3/12/2010 Physician Italy
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/8/2009 58 Female 106 lb 3/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 5/1/2007 65 Male 99 lb 5/26/2010 Consumer Japan
Primary
Concomitant
Pyrexia Other Serious 3/13/2009 16 Male 108 lb 5/26/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 4/14/2010 60 Male 110 lb 6/25/2010 Physician Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Death 55 Male 6/29/2010 Other Health Professional Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 6/25/2010 Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 7/20/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 7/21/2010 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 7/14/2010 Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 7/19/2010 Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/21/2009 37 Female 93 lb 8/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 8/11/2010 Physician Japan
Primary
Concomitant
Bacterial Sepsis Other Serious 33 Male 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 31 Female 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 19 Male 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Mycobacterium Kansasii Pneumonia Death 53 Male 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 28 Female 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 12/10/2009 5 Male 53 lb 9/1/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/13/2009 4 Female 31 lb 9/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/4/2010 63 Male 128 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Device Related Sepsis Hospitalization 11/17/2007 56 Male 179 lb 9/28/2010 Physician France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 7/22/2010 14 Female 97 lb 10/22/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/14/2009 67 Male 99 lb 10/26/2010 Consumer Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/8/2009 58 Female 106 lb 10/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 12/27/2008 52 Male 152 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/8/2009 58 Female 106 lb 11/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Oedema Life Threatening 1/29/2010 59 Male 176 lb 11/3/2010 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/27/2010 52 Female 110 lb 10/29/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Sepsis Other Serious 5/26/2009 7 Female 29 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant
Idiopathic Pneumonia Syndrome Other Serious 6/29/2010 57 Female 99 lb 11/22/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 7/17/2009 28 Male 110 lb 11/23/2010 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 7/17/2009 28 Male 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
Wheezing Other Serious 8/29/2007 59 Female 12/2/2010 Physician United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 5/21/2010 Male 154 lb 12/3/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 2/19/2010 7 Male 51 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Hyperhidrosis 12/3/2009 12/15/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/13/2009 4 Female 31 lb 12/20/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/12/2009 76 Male 119 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 3/19/2010 31 Male 139 lb 12/27/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/12/2009 76 Male 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 11/28/2009 73 Male 112 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/28/2009 55 Male 12/17/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 11/7/2010 49 Female 97 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Death 10/10/2009 72 Male 112 lb 12/30/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 11/28/2009 73 Male 112 lb 1/3/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Other Serious 11/26/2010 35 Male 110 lb 1/4/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Haemorrhage Death 4/13/2009 4 Female 31 lb 1/7/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/21/2009 1/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 1/10/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Premature Baby Hospitalization 12/25/2003 Female 4 lb 1/18/2011 Physician France
Primary
Secondary
Concomitant
Staphylococcal Infection Death 4/14/2010 60 Male 110 lb 1/20/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/17/2010 43 Female 119 lb 1/26/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 9/30/2009 18 Female 137 lb 1/28/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 7/22/2010 14 Female 97 lb 2/14/2011 Physician Japan
Primary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 10/24/2010 19 Male 115 lb 3/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/10/2011 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 1/29/2010 52 Male 132 lb 3/24/2011 Physician Japan
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/25/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Toothache Hospitalization 9/21/2009 37 Female 93 lb 4/14/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/15/2009 57 Female 106 lb 4/19/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/15/2010 54 Female 95 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Abscess Bacterial Death 11/25/2009 61 Male 141 lb 4/25/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 3/7/2011 30 Female 4/28/2011 Other Health Professional France
Primary
Secondary
Cardiac Failure Congestive Other Serious 6/29/2010 57 Female 99 lb 5/2/2011 Consumer Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 7/14/2010 Female 99 lb 5/5/2011 Physician Japan
Primary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 2/28/2011 70 Female 5/23/2011 Physician Japan
Primary
Concomitant
Candida Test Positive Hospitalization 3/12/2010 54 Female 95 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/17/2010 55 Male 168 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Mycosis Other Serious 3/2/2010 63 Male 130 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Monoplegia Hospitalization 2/28/2011 70 Female 6/10/2011 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/29/2010 52 Male 132 lb 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 7/18/2010 61 Female 110 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Death 9/2/2010 2 Female 18 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Hospitalization 9/25/2009 10 Male 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 5/25/2010 23 Female 73 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/19/2008 55 Female 99 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 2/10/2010 23 Male 117 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Life Threatening 4/22/2010 13 Male 90 lb 7/5/2011 Physician Japan
Primary
Concomitant
Memory Impairment Hospitalization 2/10/2010 23 Male 117 lb 7/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 2/18/2009 56 Female 128 lb 7/7/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Effect Decreased Death 2/1/2009 12 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 6/14/2010 7 Female 31 lb 7/8/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection 10/21/2009 7/12/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 1/1/2011 8 Female 73 lb 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Hospitalization 3/27/2010 23 Male 117 lb 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Engraft Failure Other Serious 6/9/2010 10 Female 88 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/9/2010 10 Female 88 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Gastritis Other Serious 5/21/2010 Male 154 lb 7/18/2011 Physician Japan
Primary
Concomitant
Abscess Bacterial Hospitalization 11/25/2009 61 Male 141 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Death 12/10/2009 7 Male 53 lb 7/19/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 6/18/2010 39 Female 110 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Sepsis Hospitalization 3/19/2010 31 Male 139 lb 7/29/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Test Positive Other Serious 9/13/2009 7 Female 44 lb 8/1/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/10/2010 49 Female 97 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 11/10/2010 49 Female 97 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 11/7/2010 51 Male 137 lb 8/4/2011 Physician Japan
Primary
Concomitant
Neutropenia Life Threatening 1/17/2011 27 Female 95 lb 8/5/2011 Physician Japan
Primary
Concomitant
Insomnia Other Serious 11/23/2010 62 Female 108 lb 8/8/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Abnormal Hospitalization 10/1/2008 18 Male 95 lb 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 9/27/2010 8/22/2011 Physician Japan
Primary
Concomitant

Drug Data