Aleve combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lung Adenocarcinoma Other Serious 1/18/2006 Female 2/8/2006 Other Health Professional United States
Primary
Concomitant
Disseminated Tuberculosis Other Serious 12/1/2004 Female 160 lb 2/13/2006 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 61 Female 3/6/2006 Physician United States
Primary
Concomitant
Lung Adenocarcinoma Other Serious Female 259 lb 3/10/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 59 Male 159 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 59 Male 159 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 61 Female 110 lb 3/27/2006 Physician United States
Primary
Concomitant
Muscle Spasms Hospitalization 11/17/1999 41 Female 154 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 8/1/2005 Female 171 lb 4/11/2006 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 5/9/2005 Female 4/17/2006 Physician United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 12/7/2005 Female 204 lb 4/24/2006 Physician United States
Primary
Concomitant
Sinusitis Other Serious 10/31/2004 67 Female 124 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 190 lb 9/21/2006 Consumer United States
Primary
Secondary
Concomitant
Confusional State Other Serious 10/15/2006 60 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Streptococcal Infection 5/16/2006 Female 12/14/2006 Physician United States
Primary
Concomitant
Perforated Ulcer Hospitalization 9/1/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Temporal Lobe Epilepsy Hospitalization 8/30/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/1/2006 Female 4/6/2007 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 6/14/2007 Female 195 lb 8/7/2007 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 6/14/2007 Female 195 lb 9/14/2007 Physician United States
Primary
Secondary
Concomitant
Lymphatic Disorder Other Serious 1/1/2005 Female 11/12/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 9/19/2006 75 Female 12/10/2007 Physician United States
Primary
Concomitant
Psoriatic Arthropathy 1/5/2007 Male 330 lb 12/12/2007 Physician United States
Primary
Concomitant
Urinary Tract Inflammation Required Intervention 8/21/2007 69 Female 168 lb 1/12/2008 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 12/1/2007 Female 2/6/2008 Physician United States
Primary
Concomitant
Oesophageal Pain 1/1/2007 75 Female 110 lb 3/9/2008 Consumer United States
Primary
Concomitant
Stomach Discomfort Male 201 lb 6/4/2007 Consumer United States
Primary
Concomitant
Dyspepsia 1/1/2007 70 Male 194 lb 6/21/2007 Consumer United States
Primary
Concomitant
Faeces Discoloured Other Serious 8/1/2007 87 Female 128 lb 8/17/2007 Consumer United States
Primary
Secondary
Concomitant
Faeces Discoloured Other Serious 8/16/2007 87 Female 128 lb 3/3/2008 Consumer United States
Primary
Secondary
Concomitant
Neck Pain Other Serious 3/26/2008 55 Female 119 lb 4/7/2008 Consumer United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 7/10/2000 62 Female 143 lb 6/15/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 Female 4/25/2008 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2007 Female 5/6/2008 Physician United States
Primary
Concomitant
Oesophageal Pain 1/1/2007 75 Female 110 lb 6/2/2008 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 4/19/2008 81 Male 240 lb 6/19/2008 Consumer United States
Primary
Concomitant
Neck Pain Other Serious 3/26/2008 55 Female 119 lb 7/2/2008 Consumer United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/9/2008 Male 174 lb 8/7/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 8/1/2006 Female 156 lb 10/27/2008 Consumer United States
Primary
Concomitant
Pallor Other Serious 1/1/2008 Male 169 lb 10/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance 6/13/2005 65 Female 1/31/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 151 lb 11/17/2008 Physician United States
Primary
Concomitant
Carotid Artery Stenosis Other Serious Female 178 lb 11/21/2008 Physician United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 12/27/2007 Male 286 lb 11/25/2008 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 9/15/2006 Female 11/25/2008 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 7/1/2008 73 Female 12/2/2008 Physician United States
Primary
Concomitant
Swelling 2/1/2008 Female 134 lb 12/9/2008 Other Health Professional United States
Primary
Concomitant
Tremor 2/8/2008 Male 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2007 Female 168 lb 12/12/2008 Physician United States
Primary
Concomitant
Cataract 4/1/2008 Female 120 lb 12/12/2008 Physician United States
Primary
Concomitant
Hernia 5/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Upper Limb Fracture 1/1/2008 Female 12/13/2008 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 7/1/2008 73 Female 12/16/2008 Physician United States
Primary
Concomitant
Stent Placement Other Serious 8/1/2006 Male 12/22/2008 United States
Primary
Concomitant
Tendonitis Other Serious 1/1/2008 Female 92 lb 12/22/2008 Canada
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 7/1/2008 Female 236 lb 12/23/2008 Physician United States
Primary
Concomitant
Rash Female 110 lb 1/7/2009 Consumer United States
Primary
Concomitant
Blood Pressure Increased 7/28/2008 70 Female 190 lb 1/7/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 1/30/2009 Physician United States
Primary
Concomitant
Weight Increased 66 Male 240 lb 2/9/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 3/18/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 4/1/2009 Physician United States
Primary
Concomitant
Weight Increased 66 Male 240 lb 4/7/2009 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 9/23/2008 Female 4/24/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2009 Female 147 lb 6/11/2009 Physician United States
Primary
Concomitant
Drug Ineffective 5/1/2008 Female 220 lb 6/12/2009 United States
Primary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 7/10/2009 Physician United States
Primary
Concomitant
Unevaluable Event Death Male 8/28/2009 United States
Primary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Injection Site Pain 11/1/2006 Female 140 lb 9/11/2009 Consumer United States
Primary
Concomitant
Weight Increased 5/6/2009 Female 162 lb 9/18/2009 United States
Primary
Secondary
Concomitant
Pain 6/6/2009 Male 9/18/2009 United States
Primary
Concomitant
Nausea 7/27/2009 Female 112 lb 9/19/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 204 lb 11/24/2009 Consumer United States
Primary
Concomitant
Urticaria 1/1/2007 Female 12/1/2009 Physician United States
Primary
Concomitant
Rheumatoid Nodule 12/16/2008 Male 12/3/2009 Physician United States
Primary
Concomitant
Deafness Bilateral Other Serious 1/21/2009 66 Female 150 lb 12/7/2009 Physician United States
Primary
Concomitant
Sinusitis 4/1/2009 Female 225 lb 12/9/2009 Physician United States
Primary
Concomitant
Paraesthesia 12/1/2008 Female 12/10/2009 Physician United States
Primary
Concomitant
Lobar Pneumonia Hospitalization 4/5/2010 62 Female 7/8/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Upper-airway Cough Syndrome Hospitalization 1/31/2010 53 Female 218 lb 10/27/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 12/22/2010 United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma 8/23/2010 47 Female 190 lb 12/30/2010 Physician United States
Primary
Secondary
Concomitant
Fungal Skin Infection Hospitalization 7/1/2010 1/4/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/30/2010 56 Female 279 lb 12/21/2010 Other Health Professional United States
Primary
Concomitant
Haematuria Other Serious 7/1/2010 1/6/2011 Physician United States
Primary
Concomitant
Acute Respiratory Failure Hospitalization 9/30/2010 56 Female 279 lb 1/10/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Stiffness 9/1/2009 41 Female 148 lb 1/28/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 12/14/2009 16 Female 108 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Joint Swelling 12/1/2009 59 Female 220 lb 1/28/2011 United States
Primary
Concomitant
Dizziness 2/4/2010 70 Female 136 lb 1/28/2011 United States
Primary
Concomitant
Contusion 6/1/2010 62 Female 1/29/2011 Consumer United States
Primary
Concomitant
Joint Stiffness 8/24/2010 66 Female 167 lb 1/29/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Erythema 2/1/2010 27 Female 1/29/2011 Consumer United States
Primary
Concomitant
Nausea 8/16/2010 57 Male 1/29/2011 Consumer United States
Primary
Concomitant
Muscle Strain 10/28/2010 57 Female 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 10/18/2010 54 Female 1/30/2011 Consumer United States
Primary
Concomitant
Headache Hospitalization 9/30/2010 56 Female 279 lb 2/16/2011 Other Health Professional United States
Primary
Concomitant
No Adverse Event Female 130 lb 3/10/2011 Consumer United States
Primary
Concomitant
Post Procedural Infection Other Serious 9/24/2010 69 Female 196 lb 3/28/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/7/2008 45 Female 185 lb 4/1/2011 Consumer United States
Primary
Concomitant
Weight Increased 12/5/2010 46 Male 10/28/2011 Consumer United States
Primary
Concomitant
Renal Impairment Death 80 Female 10/31/2011 Physician Germany
Primary
Secondary
Concomitant
Musculoskeletal Pain 7/28/2011 58 Female 265 lb 11/3/2011 Consumer United States
Primary
Concomitant
Arthropod Bite Male 178 lb 11/6/2011 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection 7/1/2011 61 Female 11/7/2011 Physician United States
Primary
Concomitant
Headache Other Serious 5/1/2012 56 Female 148 lb 7/11/2012 Consumer United States
Primary
Concomitant
Multiple Allergies Other Serious 11/10/2010 70 Female 8/14/2012 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 7/30/2007 44 Female 190 lb 8/24/2012 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 11/28/2003 46 Female 140 lb 10/22/2012 Physician Us
Primary
Concomitant
Cellulitis Hospitalization 8/28/2010 27 Female 164 lb 3/6/2013 Physician Us
Primary
Concomitant
Rheumatoid Arthritis 90 Female 2/19/2013 Other Health Professional Us
Primary
Concomitant
Muscle Twitching Hospitalization Female 166 lb 11/19/2012 Physician Country Not Specified
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 6/2012 69 Female 9/27/2012 Consumer Us
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 8/8/2012 57 Male 221 lb 11/26/2012 Consumer Us
Primary
Concomitant
Injection Site Rash Male 175 lb 10/23/2012 Physician Us
Primary
Concomitant
Injection Site Rash 2/24/2012 33 Female 158 lb 10/25/2012 Other Health Professional Us
Primary
Concomitant
Nasopharyngitis Female 10/24/2012 Other Health Professional Us
Primary
Concomitant
Viral Infection 77 Male 202 lb 10/24/2012 Physician Us
Primary
Concomitant
Sinus Disorder 10/12/2011 62 Female 10/25/2012 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection 2011 64 Female 200 lb 10/25/2012 Physician Us
Primary
Concomitant
Sinusitis Female 10/25/2012 Physician Us
Primary
Concomitant
Influenza Like Illness 11/16/2011 56 Male 270 lb 10/25/2012 Physician Us
Primary
Concomitant
Injection Site Pain 55 Female 10/25/2012 Physician Us
Primary
Concomitant
Drug Ineffective 3/12/2012 47 Female 226 lb 10/26/2012 Physician Us
Primary
Concomitant
Injection Site Bruising 6/1/2012 46 Female 229 lb 10/26/2012 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection 3/2/2012 55 Female 270 lb 10/26/2012 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection Female 250 lb 10/26/2012 Physician Us
Primary
Concomitant
Injection Site Reaction 50 Female 222 lb 10/26/2012 Consumer Us
Primary
Concomitant
Arthralgia Female 187 lb 10/26/2012 Physician Us
Primary
Concomitant
Swelling 5/11/2012 16 Female 200 lb 10/23/2012 Other Health Professional Us
Primary
Concomitant
Fatigue 2/6/2012 50 Female 170 lb 10/25/2012 Other Health Professional Us
Primary
Concomitant
Injection Site Bruising 3/2012 33 Female 10/25/2012 Physician Us
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2010 62 Female 128 lb 11/7/2012 Consumer Us
Primary
Secondary
Concomitant
Sepsis Death 10/12/2012 57 Female 11/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Fatigue 6/8/2011 37 Female 11/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Pneumonia 49 Female 268 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Back Pain 5/7/2012 48 Female 150 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Back Pain 5/7/2012 48 Female 150 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Oral Herpes 4/1/2004 38 Female 193 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Injection Site Swelling Other Serious Female 11/8/2012 Physician Us
Primary
Concomitant
Therapeutic Response Decreased 1/6/2011 60 Female 11/8/2012 Physician Us
Primary
Concomitant
Myocardial Fibrosis Death 10/24/2012 40 Female 131 lb 11/14/2012 Other Health Professional Us
Primary
Concomitant

Drug Data