Adalimumab combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Hospitalization 1/1/2003 65 Female 2/17/2006 Physician France
Primary
Secondary
Concomitant
Grand Mal Convulsion Life Threatening 2/19/2006 57 Female 3/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Joint Tuberculosis Other Serious 75 Female 3/28/2006 Physician Sweden
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 76 Female 10/9/2006 United Kingdom
Primary
Concomitant
Pachymeningitis Hospitalization 1/1/2004 77 Male 11/22/2006 United States
Primary
Concomitant
Diabetes Mellitus Insulin-dependent Other Serious 48 Female 207 lb 2/2/2007 France
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 9/19/2006 34 Male 2/9/2007 Physician Germany
Primary
Secondary
Concomitant
Spinal Operation Hospitalization 2/16/2006 70 Female 2/12/2007 Other Health Professional Germany
Primary
Concomitant
Prosthesis Implantation Hospitalization 9/13/2005 62 Female 2/14/2007 Other Health Professional Germany
Primary
Concomitant
Prostatic Operation Hospitalization 6/15/2006 78 Male 2/14/2007 Other Health Professional Germany
Primary
Concomitant
Interstitial Lung Disease Other Serious 77 Female 5/4/2007 United Kingdom
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 52 Male 5/16/2007 Other Health Professional Belgium
Primary
Concomitant
Vulval Cancer Stage I Hospitalization 6/1/2006 29 Female 5/31/2007 Norway
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 1/1/2007 Female 6/13/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Mucormycosis Other Serious 65 Female 6/27/2007 Consumer Finland
Primary
Secondary
Unresponsive To Stimuli Hospitalization 65 Female 7/3/2007
Primary
Secondary
Respiratory Failure Other Serious 2/14/2007 53 Female 7/5/2007 Physician Australia
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 5/1/2007 Female 126 lb 7/26/2007 Italy
Primary
Concomitant
Seroma Hospitalization 8/15/2006 45 Female 7/30/2007 Physician Germany
Primary
Secondary
Concomitant
Metastatic Bronchial Carcinoma Hospitalization 1/5/2006 66 Female 8/14/2007 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 76 Female 9/25/2007 United Kingdom
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 9/5/2007 54 Male 10/29/2007 Consumer Norway
Primary
Secondary
Concomitant
Osteonecrosis Disability 6/1/2007 76 Female 11/8/2007 Other Health Professional France
Primary
Concomitant
Disease Recurrence Hospitalization 7/23/2007 74 Male 7/31/2007 Pharmacist United States
Primary
Secondary
Diplegia Hospitalization 10/1/2007 Female 11/8/2007 Canada
Primary
Concomitant
Diplegia Hospitalization 10/1/2007 Female 11/9/2007 Canada
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 6/1/2007 54 Male 11/14/2007 Consumer Norway
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/1/2007 56 Female 141 lb 11/16/2007 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Distress Death 6/16/2006 36 Male 11/20/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 11/29/2007 Consumer France
Primary
Secondary
Concomitant
Cough Other Serious 12/21/2006 Female 165 lb 12/6/2007 Physician United States
Primary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 12/8/2007 Consumer France
Primary
Secondary
Concomitant
Hepatitis Other Serious 44 Female 1/10/2008 Argentina
Primary
Concomitant
Granuloma Other Serious 62 Female 1/25/2008 Norway
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 12/21/2007 46 Male 157 lb 1/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastatic Bronchial Carcinoma Hospitalization 1/5/2006 66 Female 2/6/2008 Physician Germany
Primary
Secondary
Concomitant
Hyperhidrosis Female 168 lb 2/8/2008 Consumer United States
Primary
Concomitant
Myocardial Rupture Other Serious 1/11/2008 Male 165 lb 2/22/2008 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 2/26/2008 Consumer France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/4/2004 Male 3/11/2008 United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 72 Female 3/13/2008 Physician Germany
Primary
Concomitant
Scleroderma Other Serious 57 Female 3/21/2008 France
Primary
Concomitant
Respiratory Distress Death 6/16/2006 36 Male 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/15/2006 70 Male 3/21/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/6/2007 Male 229 lb 3/25/2008 Physician United Kingdom
Primary
Concomitant
Skin Disorder Other Serious 11/1/2006 63 Male 3/28/2008 France
Primary
Secondary
Nephrotic Syndrome Hospitalization 3/11/2008 Male 154 lb 4/3/2008 Netherlands
Primary
Concomitant
Sinus Disorder Hospitalization 11/1/2007 Male 154 lb 4/4/2008 Netherlands
Primary
Concomitant
Sinus Disorder Hospitalization 11/1/2007 Male 154 lb 4/21/2008 Netherlands
Primary
Concomitant
Lupus-like Syndrome Other Serious 29 Female 4/24/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 3/11/2008 Male 154 lb 4/24/2008 Netherlands
Primary
Concomitant
Urticaria Female 210 lb 4/25/2008 Consumer United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 45 Female 4/25/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Scleroderma Other Serious 57 Female 4/28/2008 France
Primary
Concomitant
Hodgkin's Disease Life Threatening 10 Female 4/29/2008 Physician United States
Primary
Secondary
Breast Cancer Life Threatening 9/1/2007 58 Female 5/2/2008 Consumer United Kingdom
Primary
Secondary
Tuberculosis Hospitalization 4/1/2008 31 Female 5/13/2008 Physician Spain
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/26/2003 Female 150 lb 5/16/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization Male 5/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Biopsy Bronchus Abnormal Other Serious 40 Female 6/6/2008 Finland
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 2/15/2008 54 Female 6/10/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 50 Female 6/10/2008 Greece
Primary
Concomitant
Nephrotic Syndrome Hospitalization 3/11/2008 Male 154 lb 6/20/2008 Netherlands
Primary
Concomitant
Pulmonary Embolism Other Serious 8/9/2007 57 Female 6/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Leprosy Other Serious 47 Male 7/9/2008 United States
Primary
Concomitant
Ulcer Other Serious 1/31/2008 44 Female 169 lb 7/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Life Threatening 6/1/2006 69 Female 7/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 53 Male 8/6/2008 United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 69 Female 8/7/2008 United Kingdom
Primary
Secondary
Concomitant
Rectal Cancer Stage Iii Hospitalization 6/15/2007 69 Female 8/8/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 72 Female 8/8/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 6/15/2006 70 Male 8/8/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Life Threatening 6/1/2006 69 Female 8/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Ii Other Serious 2 Female 8/15/2008 United States
Primary
Secondary
Lung Neoplasm Malignant Hospitalization 5/6/2008 Female 128 lb 8/19/2008 Physician Netherlands
Primary
Secondary
Concomitant
Thrombosis Hospitalization 9/1/2003 Female 140 lb 8/19/2008 Consumer United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 8/27/2008 Physician United States
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Other Serious 60 Female 9/2/2008 Germany
Primary
Concomitant
Breast Cancer Hospitalization Female 9/11/2008 Other Health Professional France
Primary
Secondary
Joint Destruction Other Serious 10 Female 9/22/2008 United States
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 20 Female 9/23/2008 Italy
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 7/1/2008 Female 9/23/2008 Physician Netherlands
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/26/2008 Physician United States
Primary
Secondary
Thrombosis Other Serious 1/31/2008 44 Female 169 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/30/2008 Physician United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 10/2/2008 Other Health Professional United States
Primary
Secondary
Wheelchair User Other Serious 10 Female 10/17/2008 Physician United States
Primary
Secondary
Lymphocytic Leukaemia Hospitalization Female 11/7/2008 Physician Norway
Primary
Secondary
Concomitant
Lymphocytic Leukaemia Hospitalization Female 11/11/2008 Physician Norway
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 50 Female 11/11/2008 Greece
Primary
Concomitant
Liver Function Test Abnormal Other Serious 4/29/2008 Female 11/19/2008 Consumer United States
Primary
Concomitant
Diverticulum Hospitalization 2/1/2006 Female 11/20/2008 Germany
Primary
Concomitant
Rash Generalised 7/18/2008 Female 200 lb 11/20/2008 United States
Primary
Concomitant
Herpes Zoster Other Serious 45 Male 11/24/2008
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 47 Female 11/24/2008
Primary
Secondary
Concomitant
Chronic Sinusitis 1/1/1999 Male 154 lb 11/26/2008 Netherlands
Primary
Concomitant
Weight Decreased Other Serious 54 Male 100 lb 11/26/2008 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2000 Female 204 lb 12/2/2008 Physician United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 2/1/2006 Female 12/4/2008 Germany
Primary
Concomitant
Urticaria Other Serious 1/1/2006 47 Female 12/5/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/20/2006 Female 137 lb 12/5/2008 Consumer France
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 47 Female 12/12/2008 United States
Primary
Secondary
Concomitant
Bursitis Infective Staphylococcal Hospitalization 10/27/2008 47 Female 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Lung Infection Death 61 Female 12/29/2008 Greece
Primary
Concomitant
Lung Infection Death 61 Female 1/2/2009 Greece
Primary
Concomitant
Disseminated Tuberculosis Hospitalization 75 Female 1/14/2009 France
Primary
Concomitant
Non-small Cell Lung Cancer Life Threatening 6/1/2006 69 Female 1/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Sarcoidosis Other Serious 30 Female 1/30/2009 Italy
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 6/1/2006 69 Female 2/4/2009 United Kingdom
Primary
Secondary
Septic Shock Hospitalization 2/15/2008 54 Female 2/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Depression Death Female 2/9/2009 Other Health Professional Germany
Primary
Concomitant
Hip Arthroplasty Hospitalization 10/15/2007 67 Male 2/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Arthrodesis Other Serious 8/7/2008 50 Female 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Metastatic Bronchial Carcinoma Death 8/27/2008 72 Female 2/12/2009 Consumer United Kingdom
Primary
Concomitant
Cerebrovascular Accident Life Threatening 4/18/2008 72 Female 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Adenoma Other Serious 12/1/2007 Female 2/18/2009 Other Health Professional Spain
Primary
Concomitant
Eye Excision Other Serious 64 Male 2/26/2009 France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 2/15/2008 54 Female 3/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Granuloma Other Serious 62 Female 3/6/2009 Norway
Primary
Concomitant
Loss Of Consciousness Other Serious 2/1/2006 47 Female 3/12/2009 France
Primary
Concomitant
Uveitis Other Serious 4 Female 3/16/2009
Primary
Secondary
Concomitant
Sepsis Death 4/10/2009 Physician New Zealand
Primary
Secondary
Unevaluable Event Death 72 Female 4/10/2009 Other Health Professional Ireland
Primary
Secondary
Rectal Cancer Other Serious 2/8/2009 63 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death 4/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Tuberculosis Other Serious 29 Female 4/27/2009 South Africa
Primary
Concomitant
Pericardial Effusion Life Threatening 57 Female 5/1/2009 New Zealand
Primary
Concomitant
Pericarditis Constrictive Life Threatening 40 Male 5/1/2009 New Zealand
Primary
Concomitant
Tuberculoma Of Central Nervous System Hospitalization 60 Female 5/5/2009 Ireland
Primary
Concomitant
Hodgkin's Disease Other Serious 2 Female 5/8/2009 Other Health Professional United States
Primary
Secondary
Hodgkin's Disease Other Serious 2 Female 5/19/2009 Other Health Professional United States
Primary
Secondary
Throat Irritation Other Serious 1/1/2002 Female 147 lb 5/19/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Mycobacterium Kansasii Infection 8/1/2008 Male 152 lb 5/19/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 6/25/2004 Male 5/22/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pericarditis Constrictive Life Threatening 40 Male 5/22/2009 New Zealand
Primary
Concomitant
Lymphoma Life Threatening 2/13/2006 Female 5/26/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 1/1/2007 Female 5/26/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Sepsis Other Serious 4/17/2008 49 Male 6/29/2009
Primary
Secondary
Concomitant
Oral Discomfort Life Threatening 10/9/2006 Male 183 lb 7/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 8/2/2006 29 Female 123 lb 7/7/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 60 Female 7/15/2009
Primary
Secondary
Concomitant
Mycobacterium Kansasii Infection 8/1/2008 Male 152 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Visceral Leishmaniasis Hospitalization 60 Female 7/20/2009 Other Health Professional Spain
Primary
Secondary
Liver Injury Other Serious 1/1/2008 Female 7/29/2009 Other Health Professional United States
Primary
Secondary
Depression Other Serious Female 7/20/2009 Physician Germany
Primary
Concomitant
Osteomyelitis Hospitalization 7/10/2009 Female 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Lung Infection Death 61 Female 8/11/2009 Greece
Primary
Concomitant
Throat Irritation Other Serious 1/1/2004 Female 147 lb 8/13/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 7/10/2009 Female 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 1/1/2006 53 Female 8/19/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant

Drug Data