Cytotec combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sinus Tachycardia Hospitalization 1/1/2000 52 Male 150 lb 1/10/2006 Physician United States
Primary
Concomitant
Osteonecrosis Hospitalization 9/1/2004 Male 176 lb 2/6/2006 Physician Japan
Primary
Concomitant
Biliary Cirrhosis Primary Other Serious 2/6/2006 Female 110 lb 2/17/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/1/2005 Female 126 lb 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/1/2004 Male 176 lb 3/9/2006 Physician Japan
Primary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/12/2003 Female 126 lb 3/23/2006 Physician Japan
Primary
Secondary
Concomitant
Tracheal Injury Life Threatening 1/29/2004 70 Male 144 lb 3/27/2006 Physician Japan
Primary
Secondary
Concomitant
Tracheal Haemorrhage Life Threatening 1/29/2004 70 Male 144 lb 6/30/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/12/2003 Female 126 lb 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Hospitalization 12/30/2005 Male 9/28/2006 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Hospitalization 12/30/2005 Male 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Hospitalization 12/30/2005 Male 10/31/2006 Physician Japan
Primary
Secondary
Concomitant
Retinal Vein Occlusion Other Serious 12/31/2005 Female 104 lb 11/1/2006 Physician Japan
Primary
Secondary
Concomitant
Neck Pain Hospitalization 8/19/2006 Male 11/29/2006 Physician Japan
Primary
Concomitant
Mediastinal Abscess Hospitalization 9/27/2006 Male 12/12/2006 Physician Japan
Primary
Concomitant
Retroperitoneal Fibrosis Other Serious 5/1/2006 Male 12/21/2006 Physician Canada
Primary
Concomitant
Pruritus 5/25/2006 51 Female 168 lb 12/22/2006 Consumer United States
Primary
Concomitant
Lung Infiltration Hospitalization 1/1/2006 Female 127 lb 1/25/2007 Physician United States
Primary
Concomitant
Retroperitoneal Fibrosis Other Serious 5/1/2006 Male 1/25/2007 Physician Canada
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 12/1/2005 Female 3/21/2007 Physician Sweden
Primary
Concomitant
Pericarditis Hospitalization 7/1/2006 53 Male 4/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Osteomyelitis Chronic Hospitalization 5/25/2005 Female 119 lb 4/11/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 1/28/2006 Female 146 lb 4/25/2007 Physician Japan
Primary
Concomitant
Biliary Cirrhosis Primary Other Serious 2/6/2006 Female 110 lb 5/29/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/22/2004 Male 121 lb 6/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2004 Male 121 lb 7/6/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/12/2003 Female 126 lb 7/19/2007 Physician Japan
Primary
Secondary
Concomitant
Ureteric Cancer Other Serious 3/7/2007 Female 95 lb 7/24/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 8/15/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 8/28/2007 Consumer Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 9/20/2006 Female 88 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/1/2005 66 Male 9/4/2007 Consumer Japan
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 1/1/2007 Female 9/20/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 6/27/2005 65 Male 9/21/2007 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/27/2005 65 Male 10/11/2007 Consumer Japan
Primary
Secondary
Concomitant
Oedema Other Serious 2/21/2005 Male 137 lb 10/18/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperparathyroidism Other Serious 1/1/2007 Female 11/9/2007 Consumer United States
Primary
Concomitant
Synovitis Other Serious 9/1/2001 Female 12/6/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2004 72 Female 12/7/2007 Physician United States
Primary
Concomitant
Retinal Vein Occlusion Other Serious 12/31/2005 Female 104 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 2/10/2006 Female 146 lb 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/27/2004 Male 121 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/1/2004 72 Female 3/10/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/20/2004 Male 121 lb 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/5/2007 48 Male 200 lb 4/8/2008 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 10/1/2004 Female 5/16/2008 Physician United States
Primary
Concomitant
Central Nervous System Lymphoma Other Serious 2/1/2006 Female 117 lb 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Biliary Cirrhosis Primary Other Serious 1/23/2006 Female 110 lb 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Other Serious 2/1/2006 Female 117 lb 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Intervertebral Discitis Hospitalization 2/1/2008 Female 119 lb 8/12/2008 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 10/13/2003 72 Female 11/6/2008 Physician United States
Primary
Concomitant
Stress Fracture Hospitalization 9/1/2007 Female 12/8/2008 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 66 Female 12/22/2008 Physician United States
Primary
Concomitant
Vaginal Prolapse Other Serious 3/5/2007 Female 141 lb 12/22/2008 United Kingdom
Primary
Concomitant
Gastroenteritis Hospitalization Female 126 lb 1/2/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/20/2004 Male 121 lb 1/26/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/20/2004 Male 121 lb 2/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 10/13/2003 72 Female 5/22/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/1/2004 72 Female 5/28/2009 Physician United States
Primary
Concomitant
Sudden Death Death 6/2/2009 Female 77 lb 6/16/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 6/2/2009 Female 77 lb 7/2/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 6/2/2009 Female 77 lb 7/14/2009 Physician Japan
Primary
Concomitant
B-cell Lymphoma Hospitalization 1/30/2006 Male 9/15/2009 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/28/2009 Female 110 lb 12/17/2009 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Hospitalization 1/29/2009 Female 99 lb 12/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/28/2009 Female 110 lb 1/27/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 6/26/2009 Female 2/2/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 1/1/2004 72 Female 2/15/2010 Physician United States
Primary
Concomitant
Umbilical Hernia Other Serious Male 2/16/2010 Canada
Primary
Concomitant
Pneumonia Hospitalization 6/20/2008 Female 90 lb 2/19/2010 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 11/28/2009 Female 110 lb 2/19/2010 Other Health Professional Japan
Primary
Concomitant
Gastric Perforation Life Threatening 5/14/2009 Female 95 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 1/1/2004 72 Female 3/11/2010 Physician United States
Primary
Concomitant
Umbilical Hernia Other Serious Male 3/11/2010 Canada
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 4/12/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Hospitalization 10/3/2009 46 Male 5/19/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Hospitalization 2/15/2010 49 Male 152 lb 5/24/2010 Physician Japan
Primary
Secondary
Concomitant
Facial Palsy Other Serious 12/17/2008 47 Male 6/7/2010 Physician Japan
Primary
Concomitant
Joint Arthroplasty Hospitalization 11/5/2009 63 Female 123 lb 6/21/2010 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/1/2009 72 Female 6/17/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 6/30/2010 Physician Japan
Primary
Concomitant
Systemic Lupus Erythematosus Rash Other Serious 1/7/2010 68 Female 95 lb 7/27/2010 Physician Japan
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2009 72 Female 7/30/2010 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Rash Other Serious 1/7/2010 68 Female 95 lb 9/29/2010 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 6/3/2004 71 Male 9/29/2010 Physician Japan
Primary
Secondary
Concomitant
Viith Nerve Paralysis Other Serious 12/17/2008 47 Male 10/13/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 1/1/2009 72 Female 11/10/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Female 11/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/7/1998 75 Female 99 lb 11/29/2010 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 10/3/2009 46 Male 1/3/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 10/29/2010 73 Female 1/26/2011 Consumer United States
Primary
Concomitant
C-reactive Protein Increased Life Threatening 9/3/2010 63 Male 115 lb 1/31/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 4/7/1998 75 Female 99 lb 2/1/2011 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Rash Hospitalization 1/7/2010 68 Female 95 lb 2/7/2011 Physician Japan
Primary
Concomitant
Glaucoma Hospitalization 4/7/1998 75 Female 99 lb 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Life Threatening 9/3/2010 63 Male 115 lb 3/3/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 10/29/2010 73 Female 3/16/2011 Physician United States
Primary
Concomitant
C-reactive Protein Increased Hospitalization 1/25/2010 62 Female 108 lb 3/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Abscess Other Serious 12/17/2008 47 Male 4/5/2011 Other Health Professional Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 12/1/2009 62 Female 108 lb 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Hospitalization 1/7/2010 68 Female 95 lb 4/25/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 12/14/2009 62 Female 108 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 2/5/2011 86 Female 6/17/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/14/2011 69 Female 129 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Life Threatening 9/3/2010 63 Male 115 lb 7/13/2011 Other Health Professional Japan
Primary
Concomitant
Arrhythmia Life Threatening 4/6/2011 57 Female 88 lb 7/14/2011 Consumer Japan
Primary
Secondary
Concomitant
Death Death 2/8/2007 83 Female 8/4/2011 Physician United States
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 5/12/2011 81 Female 115 lb 8/4/2011 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Death 5/12/2011 81 Female 115 lb 8/18/2011 Physician Japan
Primary
Concomitant
Arthritis Hospitalization 5/12/2011 59 Female 128 lb 8/19/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 9/10/2008 55 Female 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Gingivitis Hospitalization 4/7/1998 75 Female 99 lb 9/21/2011 Physician United States
Primary
Secondary
Concomitant
Arthritis Hospitalization 5/12/2011 59 Female 128 lb 10/10/2011 Physician Japan
Primary
Concomitant
Ivth Nerve Paralysis Hospitalization 9/10/2008 55 Female 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Gingival Disorder Other Serious 4/7/1998 75 Female 99 lb 10/24/2011 Physician United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 4/6/2011 57 Female 88 lb 11/7/2011 Physician Japan
Primary
Secondary
Concomitant
Myalgia 7/30/2011 52 Female 177 lb 11/7/2011 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 4/7/1998 75 Female 99 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 5/12/2011 59 Female 128 lb 12/6/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/5/2011 86 Female 12/19/2011 Consumer Japan
Primary
Secondary
Concomitant
Pruritus 9/3/2011 70 Female 1/29/2012 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 1/1/2012 65 Male 2/9/2012 Consumer Canada
Primary
Concomitant
Interstitial Lung Disease Other Serious 4/21/2005 64 Male 128 lb 2/14/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 12/1/2011 39 Female 220 lb 2/16/2012 Other Health Professional United States
Primary
Concomitant
Liver Disorder Other Serious 12/17/2008 47 Male 2/17/2012 Japan
Primary
Concomitant
Oedema Peripheral Other Serious 4/7/1998 75 Female 99 lb 2/21/2012 Physician United States
Primary
Secondary
Concomitant
Oral Disorder Death 4/7/1998 75 Female 99 lb 3/8/2012 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/11/2010 69 Female 126 lb 4/6/2012 Physician Japan
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2012 52 Female 181 lb 4/25/2012 Consumer Canada
Primary
Concomitant
Nasal Congestion 3/1/2012 52 Female 181 lb 4/27/2012 Consumer Canada
Primary
Concomitant
Small Intestine Ulcer Hospitalization 9/3/2010 63 Male 115 lb 4/27/2012 Japan
Primary
Concomitant
Hip Fracture Other Serious 1/9/2012 70 Female 162 lb 5/18/2012 Physician Canada
Primary
Concomitant
Gastric Cancer Hospitalization 2/21/2012 70 Female 101 lb 5/24/2012 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Hospitalization 2/21/2012 70 Female 101 lb 6/6/2012 Physician Japan
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 4/6/2011 57 Female 88 lb 6/7/2012 Consumer Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 4/4/2009 55 Female 130 lb 7/6/2012 Japan
Primary
Secondary
Concomitant
Bone Fissure Disability 4/27/2012 63 Female 7/17/2012 Other Health Professional France
Primary
Secondary
Bone Fissure Disability 4/27/2012 63 Female 7/17/2012 Other Health Professional France
Primary
Secondary
Gastric Cancer Hospitalization 2/21/2012 70 Female 101 lb 7/17/2012 Physician Japan
Primary
Secondary
Concomitant
Bone Fissure Disability 4/27/2012 63 Female 7/18/2012 Consumer France
Primary
Secondary
Bone Fissure Disability 6/1/2010 61 Female 7/18/2012 Physician France
Primary
Secondary
Bone Fissure Disability 4/27/2012 63 Female 7/18/2012 Other Health Professional France
Primary
Secondary
Hepatic Function Abnormal Hospitalization 2/5/2011 86 Female 7/20/2012 Physician Japan
Primary
Secondary
Concomitant
Premature Labour Other Serious 7/1/2011 24 Female 7/30/2012 Physician Japan
Primary
Concomitant
Bone Fissure Disability 6/1/2010 61 Female 8/14/2012 Physician France
Primary
Secondary
Tumour Marker Increased Death 5/1/2012 64 Female 128 lb 11/29/2012 Physician Jp
Primary
Concomitant

Drug Data