Methotrexate combined with Neulasta

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Hospitalization 10/6/2005 Female 129 lb 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 5/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 2/24/2006 31 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 2/24/2006 31 Male 5/8/2006 Physician France
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/1/2006 Female 181 lb 5/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 2/24/2006 31 Male 6/27/2006 Physician France
Primary
Secondary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 8/29/2006 50 Male 9/18/2006 Physician Israel
Primary
Concomitant
Febrile Neutropenia Life Threatening 7/1/2006 51 Male 132 lb 10/16/2006 Physician France
Primary
Concomitant
Sepsis Hospitalization 1/27/2007 Female 134 lb 3/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/16/2006 Female 169 lb 3/19/2007 Physician United Kingdom
Primary
Secondary
Dyspnoea Other Serious 2/12/2007 Female 170 lb 3/23/2007 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased 14 Male 174 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2007 Physician United States
Primary
Concomitant
Pharyngolaryngeal Pain Male 3/28/2007 Other Health Professional United States
Primary
Concomitant
Neutrophil Count Decreased 7/24/2006 21 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Injection Site Pain 1/1/2006 Female 3/28/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain 2/2/2006 Female 3/28/2007 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 2/12/2007 55 Female 170 lb 5/21/2007 Consumer United States
Primary
Secondary
Angioedema Hospitalization 5/1/2007 Male 5/25/2007 Physician Australia
Primary
Concomitant
Pyrexia Life Threatening 12/16/2006 59 Female 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 2/12/2007 Female 170 lb 6/26/2007 United Kingdom
Primary
Secondary
Vomiting Hospitalization 5/14/2007 59 Female 146 lb 7/24/2007 Physician France
Primary
Secondary
Thrombophlebitis Life Threatening 6/1/2007 56 Female 198 lb 9/13/2007 France
Primary
Secondary
Concomitant
Sepsis Death 7/3/2007 Female 9/25/2007 Physician Greece
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 7/10/2007 Male 132 lb 10/2/2007 Physician Portugal
Primary
Concomitant
Neutropenia Hospitalization 2/6/2008 Female 2/19/2008 Pharmacist United Kingdom
Primary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/27/2007 58 Male 3/28/2008 Physician France
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/22/2007 46 Female 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 12/6/2007 32 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Abnormal Other Serious 6/5/2006 40 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Abnormal Other Serious 2/14/2007 42 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 1/17/2008 51 Female 4/21/2008 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Pyrexia Life Threatening 12/16/2006 59 Female 8/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 Female 10/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Deafness Disability 8/18/2008 Female 193 lb 10/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 52 Female 11/3/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/3/2008 52 Female 11/19/2008 Physician United States
Primary
Secondary
Deafness Disability 8/18/2008 46 Female 11/17/2008 United Kingdom
Primary
Secondary
Concomitant
Deafness Disability 8/18/2008 46 Female 192 lb 11/26/2008 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/23/2008 Female 11/26/2008 Pharmacist United Kingdom
Primary
Concomitant
Deafness Disability 8/18/2008 46 Female 11/26/2008 Consumer United Kingdom
Primary
Secondary
Odynophagia Hospitalization 8/28/2008 43 Female 12/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Disability 8/18/2008 Female 193 lb 12/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/26/2009 25 Female 159 lb 2/5/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Urticaria Female 3/18/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 6/15/2007 66 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/16/2007 54 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Alanine Aminotransferase Abnormal Other Serious 12/17/2007 50 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization Female 196 lb 5/18/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/1/2009 67 Male 5/22/2009 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 12/15/2008 Female 196 lb 6/8/2009 Physician United Kingdom
Primary
Concomitant
Vasculitic Rash Hospitalization 5/1/2009 67 Male 169 lb 6/9/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Leukocytosis Other Serious 5/8/2009 Male 179 lb 7/22/2009 Physician Switzerland
Primary
Secondary
White Blood Cell Count Decreased Other Serious 7/27/2009 Female 8/10/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 8/14/2009 Physician Greece
Primary
Concomitant
Febrile Neutropenia Other Serious 8/14/2009 Physician Greece
Primary
Concomitant
Neutropenia Other Serious 8/14/2009 Physician Greece
Primary
Concomitant
Urticaria Other Serious 1/1/2009 Female 141 lb 8/24/2009 Physician Australia
Primary
Concomitant
Dyspnoea Hospitalization 1/23/2009 9/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/26/2009 Female 10/14/2009 Physician United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 6/26/2009 Female 10/27/2009 Physician United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 1/23/2009 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukocytosis Other Serious 5/8/2009 46 Male 179 lb 11/4/2009 Physician United States
Primary
Secondary
Leukocytosis Other Serious 46 Male 179 lb 11/6/2009 Physician Switzerland
Primary
Secondary
Leukocytosis Other Serious 5/8/2009 Male 11/10/2009 Physician United Kingdom
Primary
Secondary
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 10/26/2009 Male 149 lb 11/11/2009 United States
Primary
Secondary
Neutropenia Other Serious 12/29/2009 United Kingdom
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 1/17/2010 Female 2/4/2010 Physician France
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 11/26/2009 Male 2/15/2010 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 4/22/2003 Female 148 lb 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 7/1/2005 Female 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2010 Male 130 lb 3/9/2010 Physician France
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/26/2009 Male 3/25/2010 Physician France
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 4/9/2010 Physician United States
Primary
Concomitant
Splenic Rupture Hospitalization 8/21/2009 64 Female 134 lb 4/9/2010 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 12/14/2009 60 Male 4/8/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/16/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 4/19/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/19/2010 Physician France
Primary
Concomitant
Vomiting Other Serious 2/10/2010 34 Male 130 lb 4/21/2010 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/22/2010 United States
Primary
Concomitant
Headache Hospitalization 3/26/2010 25 Female 5/3/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 11/26/2009 19 Male 5/7/2010 Other Health Professional France
Primary
Secondary
Concomitant
Stomatitis Hospitalization 12/14/2009 60 Male 6/1/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 7/19/2010 United States
Primary
Concomitant
Septic Shock Death 7/13/2010 54 Male 121 lb 7/21/2010 Physician France
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 7/22/2010 United States
Primary
Concomitant
Tachycardia Other Serious 25 Female 102 lb 7/27/2010 Physician United States
Primary
Concomitant
Neutrophil Count Increased Other Serious 5/23/2010 55 Female 108 lb 7/27/2010 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 8/6/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 8/16/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 8/16/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/24/2010 United States
Primary
Concomitant
Neutropenia Other Serious 4/26/2010 Female 8/30/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/31/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 255 lb 9/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/29/2006 48 Female 163 lb 9/13/2010 Physician Greece
Primary
Secondary
Concomitant
Pain Other Serious 7/21/2006 57 Female 172 lb 9/16/2010 Physician Greece
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 9/22/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2010 10/21/2010 Physician Belgium
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/26/2010 11/12/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Urinary Retention Hospitalization 11/22/2010 77 Male 172 lb 11/22/2010 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 1/9/2004 69 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Hospitalization 7/22/2006 43 Female 137 lb 1/17/2011 Other Health Professional Greece
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/26/2011 72 Male 280 lb 2/2/2011 Physician United States
Primary
Concomitant
Staphylococcal Skin Infection Other Serious 10/3/2003 46 Female 128 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/9/2004 69 Female 3/23/2011 Other Health Professional United States
Primary
Concomitant
Myalgia Female 4/5/2011 Other Health Professional United States
Primary
Concomitant
Hypercalcaemia Hospitalization 10/3/2003 46 Female 128 lb 4/5/2011 United States
Primary
Concomitant
Paraesthesia Hospitalization 12/14/2009 60 Male 3/29/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Nausea Hospitalization 4/25/2011 49 Male 148 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Failure To Thrive Other Serious 1/9/2004 69 Female 5/13/2011 Physician United States
Primary
Concomitant
Nausea Hospitalization 4/25/2011 49 Male 150 lb 5/9/2011 Other Health Professional United States
Primary
Secondary
Urosepsis Hospitalization 1/9/2004 69 Female 5/17/2011 Lawyer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 10/9/2008 60 Male 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 6/10/2010 Male 150 lb 6/13/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Hospitalization 4/11/2011 56 Male 208 lb 7/5/2011 Other Health Professional United States
Primary
Secondary
Hypersensitivity Hospitalization 6/17/2011 Male 154 lb 7/18/2011 Other Health Professional France
Primary
Concomitant
Ligament Injury Hospitalization 11/29/2006 47 Female 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 10/3/2003 46 Female 128 lb 7/20/2011 Physician United States
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/25/2011 60 Female 137 lb 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Lesion Other Serious 11/29/2006 47 Female 7/29/2011 Physician United States
Primary
Secondary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Night Sweats Other Serious 11/29/2006 47 Female 160 lb 8/8/2011 Physician United States
Primary
Secondary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/25/2011 60 Female 137 lb 8/25/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Infection Death 9/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/25/2011 60 Female 137 lb 9/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Enteropathy Hospitalization 1/9/2004 62 Female 10/3/2011 Other Health Professional United States
Primary
Concomitant
Photosensitivity Reaction Disability 5/18/2011 58 Male 187 lb 10/4/2011 Other Health Professional Australia
Primary
Secondary

Drug Data