Bisoprolol combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 1/25/2006 Physician Belgium
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/29/2005 Female 130 lb 2/3/2006 Physician Belgium
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 1/4/2005 57 Female 143 lb 2/8/2006 Germany
Primary
Concomitant
Palpitations Other Serious 1/13/2006 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 7/15/2005 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Oedema Life Threatening 2/20/2005 Female 2/17/2006 Physician Belgium
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 4/25/2006 Consumer United States
Primary
Secondary
Concomitant
Diverticular Perforation Other Serious 4/7/2004 Female 132 lb 5/11/2006 Germany
Primary
Concomitant
Motor Neurone Disease Other Serious 3/15/2006 Male 187 lb 3/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 5/3/2005 Male 181 lb 3/7/2007 Consumer United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization 12/4/2006 Female 198 lb 7/12/2007 Physician Germany
Primary
Secondary
Concomitant
Gastric Ulcer Death 8/1/2007 Male 205 lb 9/4/2007 Physician Poland
Primary
Concomitant
Motor Neurone Disease Other Serious 3/15/2006 Male 187 lb 9/5/2007 Physician United Kingdom
Primary
Concomitant
Motor Neurone Disease Other Serious 3/15/2006 Male 187 lb 9/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 3/1/2007 Male 161 lb 9/5/2007 Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/1/2007 Male 161 lb 9/21/2007 Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/16/2007 Male 9/27/2007 Australia
Primary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/5/2007 Male 12/20/2007 Australia
Primary
Concomitant
Pleural Effusion Life Threatening 11/1/2007 Male 161 lb 12/21/2007 Physician Germany
Primary
Concomitant
Lymphadenopathy Hospitalization 10/3/2006 48 Female 12/26/2007 Physician Netherlands
Primary
Concomitant
Pneumonia Legionella Hospitalization 1/8/2008 69 Male 181 lb 2/8/2008 Physician Italy
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/1/2007 Male 161 lb 2/8/2008 Germany
Primary
Secondary
Concomitant
Hypertonia Hospitalization Female 1/26/2009 Germany
Primary
Concomitant
Synovial Cyst Other Serious 6/20/2008 Female 211 lb 1/27/2009 Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2008 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 12/9/2008 Female 154 lb 1/30/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypertonia Hospitalization Female 2/3/2009 Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/28/2008 Female 163 lb 2/4/2009 Germany
Primary
Secondary
Concomitant
Visual Field Defect Hospitalization 2/21/2008 Male 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 4/6/2008 Male 220 lb 2/19/2009 Czech Republic
Primary
Secondary
Concomitant
Eye Excision Other Serious 1/29/2009 Female 198 lb 2/20/2009 Consumer United Kingdom
Primary
Concomitant
Dyspepsia Hospitalization 10/27/2008 68 Female 2/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 9/8/2008 74 Female 150 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperglycaemia Life Threatening 1/3/2009 67 Female 3/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Nail Dystrophy Disability 1/1/2007 70 Female 161 lb 3/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/30/2008 Male 3/19/2009 United Kingdom
Primary
Concomitant
Obliterative Bronchiolitis Hospitalization 10/30/2007 Female 88 lb 4/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Life Threatening 9/1/2008 65 Female 180 lb 4/22/2009 United Kingdom
Primary
Secondary
Concomitant
Bacterial Infection Hospitalization 3/6/2009 Female 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Lower Limb Fracture Hospitalization 3/11/2009 Female 5/12/2009 Germany
Primary
Concomitant
Hypertension Hospitalization 3/27/2008 Female 5/12/2009 Consumer United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization 3/11/2009 Female 150 lb 6/12/2009 Germany
Primary
Concomitant
Pancytopenia Required Intervention 1/9/2009 80 Female 172 lb 6/12/2009 Pharmacist United States
Primary
Concomitant
Kidney Enlargement Other Serious 4/29/2009 Female 6/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Colorectal Cancer Stage Iii Other Serious 5/15/2008 Female 7/24/2009
Primary
Concomitant
Hypotension Hospitalization 9/8/2008 74 Female 150 lb 7/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/6/2009 Female 84 lb 7/29/2009 Germany
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/17/2009 Other Health Professional Canada
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 11/15/2008 51 Male 181 lb 8/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Accidental Needle Stick 12/25/2007 Female 210 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 6/1/2008 Female 155 lb 9/18/2009 Canada
Primary
Concomitant
Pollakiuria 6/3/2009 Female 200 lb 9/19/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 52 220 lb 9/23/2009 Physician Germany
Primary
Secondary
Concomitant
Vasculitis Other Serious 52 Male 220 lb 10/5/2009
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/28/2008 Male 10/16/2009 United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/10/2009 81 Female 10/17/2009 Consumer Canada
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/2/2009 Australia
Primary
Concomitant
Pulmonary Embolism Other Serious 2/20/2007 Female 132 lb 11/25/2009 Consumer United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/10/2009 81 Female 11/25/2009 Consumer Canada
Primary
Concomitant
Skin Ulcer Disability 12/25/2008 66 Female 12/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/23/2007 Female 150 lb 11/30/2009 Physician Germany
Primary
Concomitant
Dyspepsia Hospitalization 10/27/2008 68 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 Female 123 lb 12/8/2009 Physician Germany
Primary
Secondary
Concomitant
Death Death Male 190 lb 2/15/2010 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 1/23/2010 76 Male 2/4/2010 Physician Belgium
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 2/23/2010 Australia
Primary
Concomitant
Pneumonia Hospitalization 2/23/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 65 Male 165 lb 3/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 6/2/2009 Male 3/15/2010 United Kingdom
Primary
Concomitant
Anaphylactic Reaction Other Serious 65 Male 3/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Anaphylactic Reaction Other Serious 2/16/2010 65 Male 165 lb 3/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization 3/27/2009 Male 3/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Obliterative Bronchiolitis Hospitalization 10/30/2007 71 Female 88 lb 4/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/18/2009 65 Male 170 lb 4/15/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 6/15/2009 56 Female 4/16/2010 United Kingdom
Primary
Concomitant
Panic Attack Other Serious 1/1/2009 Female 4/19/2010 Consumer United Kingdom
Primary
Concomitant
Serum Sickness-like Reaction Hospitalization 3/17/2010 63 Male 4/26/2010 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 4/6/2010 58 Female 141 lb 4/26/2010 Germany
Primary
Concomitant
Sleep Apnoea Syndrome Death Male 190 lb 5/6/2010 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization 3/27/2009 75 Male 176 lb 5/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/1/2010 56 Male 205 lb 5/28/2010 Pharmacist Belgium
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2010 56 Male 176 lb 6/3/2010 Pharmacist Belgium
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 4/6/2010 58 Female 141 lb 6/1/2010 Germany
Primary
Concomitant
Renal Failure Hospitalization 62 Male 6/17/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Legionella Hospitalization 1/8/2008 69 Male 181 lb 6/25/2010 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/31/2009 69 Male 187 lb 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Panic Attack Hospitalization 73 Female 7/13/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 7/16/2010 Physician Australia
Primary
Concomitant
Synovitis Hospitalization 12/22/2009 70 Female 152 lb 7/27/2010 Other Health Professional Germany
Primary
Concomitant
Panic Attack Hospitalization 11/15/2009 73 Female 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 63 Male 8/18/2010 Physician Australia
Primary
Concomitant
Skin Papilloma Hospitalization 2/1/2010 78 Female 179 lb 10/6/2010 Physician Hungary
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/29/2009 65 Female 119 lb 9/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/11/2010 72 Female 196 lb 10/20/2010 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Other Serious 3/15/2009 10/29/2010 Physician United Kingdom
Primary
Concomitant
Colon Cancer Other Serious 8/14/2010 44 Male 220 lb 11/3/2010 Other Health Professional Canada
Primary
Concomitant
Skin Papilloma Hospitalization 2/1/2010 78 Female 179 lb 11/3/2010 Physician Hungary
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 4/6/2010 58 Female 141 lb 10/22/2010 Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/24/2010 62 Female 196 lb 11/8/2010 Physician Germany
Primary
Secondary
Concomitant
Salivary Gland Adenoma Hospitalization 1/28/2006 64 Female 11/30/2010 Other Health Professional Austria
Primary
Concomitant
Terminal State Other Serious 9/1/2009 69 Male 165 lb 12/3/2010 Consumer Netherlands
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/24/2010 62 Female 196 lb 12/10/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/1/2009 69 Male 165 lb 12/13/2010 Consumer Netherlands
Primary
Concomitant
Therapeutic Response Decreased 5/1/2009 12/19/2010 Physician United States
Primary
Concomitant
Melaena Life Threatening 1/1/2009 67 Female 12/28/2010 Consumer Germany
Primary
Concomitant
Interacting
Rheumatoid Nodule Removal Hospitalization 8/1/2010 12/28/2010 Consumer Germany
Primary
Concomitant
Hyperglycaemia Life Threatening 1/1/2009 67 Female 256 lb 12/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Hospitalization 3/27/2009 75 Male 176 lb 12/29/2010 Other Health Professional Germany
Primary
Concomitant
Dyspnoea Hospitalization 7/9/2010 87 Male 159 lb 12/30/2010 Physician Netherlands
Primary
Secondary
Concomitant
Dehydration Hospitalization 9/8/2008 74 Female 150 lb 1/4/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fungal Infection Hospitalization 9/1/2009 69 Male 165 lb 1/12/2011 Consumer Netherlands
Primary
Concomitant
Feeling Abnormal 4/12/2010 68 Female 220 lb 1/29/2011 Consumer United States
Primary
Concomitant
Arthritis Hospitalization 3/1/2010 64 Male 2/1/2011 Physician United Kingdom
Primary
Concomitant
Alopecia Hospitalization 10/21/2010 73 Female 2/6/2011 Consumer Japan
Primary
Secondary
Concomitant
Panic Attack Hospitalization 11/15/2009 73 Female 2/9/2011 Consumer Germany
Primary
Secondary
Concomitant
Aphagia Hospitalization 12/14/2010 26 Female 95 lb 2/22/2011 Consumer Canada
Primary
Concomitant
Pneumonia Hospitalization 80 Female 3/16/2011 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 65 Female 3/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 1/1/2010 65 Female 3/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombosis Death 80 Female 3/18/2011 Physician Germany
Primary
Secondary
Concomitant
Oedema Hospitalization 11/19/2009 54 Female 3/18/2011 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/24/2011 56 Female 291 lb 3/18/2011 Physician Germany
Primary
Concomitant
Confusional State Hospitalization 1/27/2011 75 Female 3/23/2011 Other Health Professional France
Primary
Secondary
Concomitant
Neck Pain Hospitalization 1/1/2010 65 Female 3/23/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Tracheostomy Hospitalization 2/1/2010 66 Male 223 lb 3/24/2011 Physician United States
Primary
Concomitant
Lung Infection Hospitalization 12/3/2010 61 Male 3/28/2011 Physician France
Primary
Secondary
Concomitant
Laryngitis Other Serious 1/1/2011 67 Female 139 lb 4/1/2011 Consumer Netherlands
Primary
Concomitant
Pilonidal Cyst Other Serious 10/1/2010 55 Male 209 lb 4/13/2011 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 12/14/2010 26 Female 95 lb 4/5/2011 Consumer Canada
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/14/2011 65 Male 152 lb 4/18/2011 Consumer Spain
Primary
Concomitant
Injection Site Erythema Other Serious 2/16/2009 84 Male 6/28/2011 Austria
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 7/1/2009 58 Female 7/21/2011 Physician India
Primary
Concomitant
Basal Cell Carcinoma Other Serious 1/1/2009 68 Male 7/22/2011 Physician Italy
Primary
Secondary
Concomitant
Multi-organ Failure Death 2/1/2011 66 Female 185 lb 9/29/2011 Physician France
Primary
Concomitant
Bile Duct Cancer Hospitalization 5/5/2011 71 Female 10/7/2011 Physician Germany
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/16/2011 61 Female 231 lb 10/7/2011 Other Health Professional Canada
Primary
Concomitant
Malignant Pleural Effusion Hospitalization 10/25/2010 62 Female 86 lb 10/12/2011 Physician Germany
Primary
Concomitant
Retroperitoneal Fibrosis Other Serious Female 119 lb 10/25/2011 Physician Netherlands
Primary
Concomitant
Gastric Ulcer Other Serious 10/11/2011 68 Female 198 lb 11/7/2011 Physician Austria
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/28/2011 79 Female 136 lb 12/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 11/28/2011 84 Female 1/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious 8/30/2011 53 Male 1/20/2012 Pharmacist Spain
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 8/30/2011 53 Male 1/30/2012 Other Health Professional Spain
Primary
Secondary
Concomitant

Drug Data