Co-Codamol combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lung Squamous Cell Carcinoma Stage Unspecified Life Threatening 6/1/2005 57 Male 1/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Folliculitis Other Serious 11/2/2005 Female 293 lb 2/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 1/13/2006 Female 176 lb 2/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/11/2006 Female 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 1/13/2006 Female 176 lb 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 11/1/2005 Male 192 lb 2/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious 1/28/2006 Male 249 lb 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Folliculitis Other Serious 9/14/2005 Female 293 lb 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 10/1/2005 15 Female 3/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/10/2006 50 Male 143 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prolapse Repair Other Serious 6/21/2005 Female 143 lb 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/10/2006 61 Male 4/4/2006 Consumer United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious 1/28/2006 Male 249 lb 4/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/10/2006 61 Male 4/13/2006 Consumer United Kingdom
Primary
Concomitant
Death Other Serious Male 139 lb 1/11/2007 Consumer United Kingdom
Primary
Concomitant
Adverse Drug Reaction Other Serious 10/29/2003 Male 170 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious Female 137 lb 1/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/25/2006 Female 139 lb 1/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 1/2/2005 Male 176 lb 1/31/2007 Consumer United Kingdom
Primary
Concomitant
Mobility Decreased Other Serious 12/22/2006 Female 134 lb 3/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Other Serious 8/14/2006 Female 137 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Other Serious 3/22/2006 Male 192 lb 4/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Prostatic Disorder Other Serious 7/5/2006 Male 163 lb 4/16/2007 Consumer United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious 2/22/2007 Male 190 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Other Serious 3/22/2006 Male 192 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/25/2006 Female 139 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Food Poisoning Other Serious 4/1/2007 Female 117 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Hospitalization 1/1/2006 Female 183 lb 5/10/2007 Physician United Kingdom
Primary
Concomitant
Gastric Cancer Stage Iv Other Serious 6/5/2007 49 Female 10/4/2007 Consumer United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 5/17/2007 Female 128 lb 10/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Smear Cervix Abnormal Other Serious 2/1/2005 Female 99 lb 10/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 8/19/2007 Female 302 lb 11/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Knee Arthroplasty Other Serious 3/7/2007 Female 187 lb 11/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenic Sepsis Other Serious Female 132 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 10/26/2007 57 Female 12/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/21/2007 Female 132 lb 12/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 3/17/2007 Male 137 lb 1/18/2008 Consumer United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 12/21/2007 46 Male 157 lb 1/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 12/21/2007 46 Male 157 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Life Threatening 12/21/2007 46 Male 157 lb 1/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 3/28/2007 Female 1/30/2008 Consumer United Kingdom
Primary
Concomitant
Overdose Other Serious 61 Female 1/26/2008 Consumer United Kingdom
Primary
Concomitant
Myopathy Other Serious 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 6/29/2005 Female 130 lb 2/26/2008 Consumer United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 1/31/2008 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Uterine Polyp Other Serious 1/15/2007 Female 137 lb 8/3/2008 Physician United Kingdom
Primary
Concomitant
Breast Cancer Metastatic Death 74 Female 8/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 1/6/2008 Female 8/20/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/11/2008 Female 8/21/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious 6/15/2008 59 Female 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Death 3/19/2009 80 Female 185 lb 8/20/2009 United Kingdom
Primary
Concomitant
Hernia Hospitalization 3/18/2005 Male 196 lb 9/10/2009 United Kingdom
Primary
Concomitant
Colonic Polyp Other Serious 5/17/2009 Female 157 lb 9/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lymphadenopathy Other Serious 3/13/2009 55 Female 9/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Column Stenosis Hospitalization 3/15/2009 Female 9/22/2009 United Kingdom
Primary
Concomitant
Breast Mass Hospitalization 5/14/2008 Female 139 lb 9/22/2009 United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 7/27/2009 Female 121 lb 9/28/2009 United Kingdom
Primary
Concomitant
Vomiting Other Serious 12/31/2008 Female 119 lb 9/28/2009 United Kingdom
Primary
Concomitant
Glioblastoma Hospitalization 1/2/2009 Female 126 lb 9/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Test Positive Other Serious 7/27/2009 Female 121 lb 9/29/2009 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/7/2005 Female 10/6/2009 United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Other Serious 1/1/2006 Male 10/7/2009 United Kingdom
Primary
Concomitant
Malaise Other Serious 1/27/2008 Female 104 lb 10/9/2009 United Kingdom
Primary
Concomitant
Tuberculosis Test Positive Other Serious 7/27/2009 Female 121 lb 10/9/2009 United Kingdom
Primary
Concomitant
Mobility Decreased Other Serious 12/18/2006 Male 176 lb 10/9/2009 United Kingdom
Primary
Concomitant
Pleural Disorder Other Serious 4/1/2008 Male 176 lb 10/9/2009 United Kingdom
Primary
Concomitant
Rales Other Serious 7/1/2009 50 Male 165 lb 10/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Coldness Other Serious 12/18/2006 Male 176 lb 10/16/2009 United Kingdom
Primary
Concomitant
Vaginal Discharge Disability 7/1/2009 71 Female 139 lb 10/16/2009 Physician United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Death 6/1/2008 Male 205 lb 10/16/2009 United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 35 Male 10/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Impaired Healing Other Serious 1/1/2009 Female 139 lb 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Clostridial Infection Other Serious 7/7/2009 Female 99 lb 11/16/2009 United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/4/2007 Male 11/18/2009 United Kingdom
Primary
Concomitant
Anal Cancer Other Serious 3/22/2009 56 Male 187 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/4/2007 Male 11/19/2009 United Kingdom
Primary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 4/15/2006 Male 11/20/2009 United Kingdom
Primary
Concomitant
Menorrhagia Disability 10/3/2003 44 Female 119 lb 11/18/2009 United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization 12/9/2003 Female 123 lb 12/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Nephrolithiasis Hospitalization 6/1/2009 Male 12/2/2009 Consumer United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 2/6/2007 Female 157 lb 12/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Extrapulmonary Tuberculosis Other Serious 7/19/2004 Female 163 lb 12/11/2009 United Kingdom
Primary
Concomitant
Renal Cancer Recurrent Other Serious 2/15/2008 Male 192 lb 12/8/2009 United Kingdom
Primary
Concomitant
Thermal Burn Other Serious 6/1/2009 Male 110 lb 12/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 3/4/2009 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cholecystectomy Hospitalization 10/15/2009 Female 1/26/2010 United Kingdom
Primary
Concomitant
Overdose Hospitalization 62 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 10/22/2009 Female 2/5/2010 United Kingdom
Primary
Concomitant
Metastatic Neoplasm Life Threatening 9/3/2009 Female 168 lb 2/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Infected Skin Ulcer Hospitalization 11/17/2008 Female 187 lb 2/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 5/15/2009 Female 205 lb 2/19/2010 United Kingdom
Primary
Concomitant
Oesophageal Squamous Cell Carcinoma Metastatic Other Serious 3/17/2010 10/28/2010 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Other Serious 3/15/2009 10/29/2010 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 4/30/2009 67 Male 148 lb 11/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/11/2010 73 Female 130 lb 11/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 5/1/2009 11/3/2010 Physician United Kingdom
Primary
Concomitant
Throat Cancer Other Serious 1/18/2008 56 Male 181 lb 11/8/2010 Consumer United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2008 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/5/2009 81 Female 176 lb 11/12/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 3/10/2010 77 Male 187 lb 11/16/2010 Physician United Kingdom
Primary
Concomitant
Parathyroid Disorder Other Serious 7/1/2010 79 Female 96 lb 11/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2008 11/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10/1/2009 69 Male 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Squamous Cell Carcinoma Other Serious 10/18/2010 80 Male 156 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cancer Metastatic Other Serious 2/15/2008 68 Male 192 lb 11/25/2010 United Kingdom
Primary
Concomitant
Breast Cancer Female Life Threatening 11/19/2010 12/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 11/24/2010 57 Female 148 lb 12/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious 2/22/2007 69 Male 190 lb 12/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Amnesia Hospitalization 9/21/2010 56 Female 154 lb 1/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pallor Hospitalization 12/19/2010 1/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Hospitalization 12/19/2010 57 Female 212 lb 1/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 12/25/2010 55 Female 2/9/2011 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 4/15/2010 63 Female 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Colon Cancer Death Male 2/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Artery Dissection Life Threatening 1/1/2011 29 Female 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Coma Hospitalization 1/21/2011 72 Male 2/23/2011 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 65 Female 2/24/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neck Pain Hospitalization 1/1/2010 65 Female 2/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2010 65 Female 3/1/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 1/1/2010 65 Female 3/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Paget's Disease Of The Breast Life Threatening 12/20/2009 47 Female 143 lb 3/4/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Cancer Hospitalization 11/1/2010 64 Male 3/7/2011 Physician United Kingdom
Primary
Concomitant
Convulsion Hospitalization 1/21/2011 72 Male 3/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 1/1/2010 65 Female 3/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 1/22/2010 64 Female 163 lb 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bladder Neoplasm Other Serious 11/12/2008 67 Male 3/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 10/11/2010 73 Female 130 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2010 65 Female 3/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 1/1/2010 65 Female 3/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 3/5/2012 64 Male 12/20/2012 Other Health Professional Gb
Primary
Concomitant
Vasculitis Other Serious 5/8/2012 79 Female 122 lb 10/17/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 10/24/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 9/27/2007 35 Female 172 lb 12/17/2012 Physician Gb
Primary
Concomitant
Metastasis Life Threatening 2010 56 Female 9/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 9/25/2012 59 Female 227 lb 10/22/2012 Physician Gb
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 2010 Female 10/22/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Lung Cancer Metastatic Life Threatening 8/30/2012 59 Female 130 lb 10/23/2012 Consumer Gb
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/13/2011 76 Male 176 lb 2/8/2013 Physician Gb
Primary
Concomitant
Pneumonia Other Serious 10/2012 Female 12/3/2012 Other Health Professional Gb
Primary
Concomitant
Pneumonia Death 11/8/2012 80 Female 12/5/2012 Other Health Professional Gb
Primary
Concomitant
Spinal Cord Compression Death 7/2012 61 Male 12/4/2012 Physician Gb
Primary
Concomitant
Electrocardiogram St Segment Depression Hospitalization 2012 57 Male 176 lb 12/18/2012 Pharmacist Gb
Primary
Concomitant
Psoriasis Hospitalization 8/9/2012 49 Female 163 lb 12/19/2012 Physician Gb
Primary
Concomitant
Ovarian Cyst Hospitalization 12/29/2011 54 Female 143 lb 2/8/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Pneumonia Death 2011 79 Female 3/22/2013 Other Health Professional Gb
Primary
Concomitant
Femoral Neck Fracture Hospitalization 5/23/2012 Male 2/7/2013 Physician Gb
Primary
Concomitant
Dissociation Other Serious 50 Male 2/15/2013 Physician Gb
Primary
Concomitant
Viral Infection Hospitalization 8/13/2012 35 Female 223 lb 2/25/2013 Other Health Professional Country Not Specified
Primary
Concomitant

Drug Data