Methotrexate combined with Simponi

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Legionella Hospitalization 6/26/2009 Male 160 lb 7/27/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 7/1/2009 Female 185 lb 10/26/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 9/28/2009 Female 11/12/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 10/5/2009 Female 130 lb 11/18/2009 Consumer United States
Primary
Concomitant
Rhinorrhoea Other Serious 11/1/2009 Female 12/15/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 10/1/2009 Female 116 lb 1/8/2010 Physician United States
Primary
Concomitant
Rhinorrhoea Other Serious 11/1/2009 Female 1/26/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2009 Female 240 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Pain In Extremity Other Serious 1/24/2010 Female 2/23/2010 Consumer Canada
Primary
Concomitant
Medical Device Complication Hospitalization 1/1/2010 Female 120 lb 3/1/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious Male 170 lb 3/5/2010 Consumer Canada
Primary
Concomitant
Facial Palsy Other Serious 2/1/2010 Male 3/9/2010 Physician Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2009 Male 230 lb 3/9/2010 Consumer United States
Primary
Concomitant
Rheumatoid Lung Hospitalization 2/1/2010 Female 113 lb 3/16/2010 Consumer Canada
Primary
Concomitant
Vision Blurred Other Serious 2/20/2010 Female 3/18/2010 Other Health Professional Canada
Primary
Concomitant
Abdominal Operation Other Serious 2/4/2010 45 Male 3/23/2010 Consumer United States
Primary
Concomitant
Medical Device Complication Hospitalization 1/1/2010 Female 120 lb 3/24/2010 Consumer United States
Primary
Concomitant
Urticaria Life Threatening 1/1/2010 Male 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 3/20/2010 56 Female 3/30/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 4/2/2010 Physician United States
Primary
Secondary
Concomitant
Tonsillar Disorder Other Serious 3/26/2010 69 Female 120 lb 4/12/2010 Consumer United States
Primary
Concomitant
Swollen Tongue Other Serious 3/26/2010 67 Male 240 lb 4/13/2010 Consumer United States
Primary
Concomitant
Muscle Spasms Hospitalization 3/13/2010 43 Female 4/15/2010 Consumer Canada
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 1/1/2010 63 Female 123 lb 4/20/2010 Consumer United States
Primary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 2/10/2010 77 Female 173 lb 4/20/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Hospitalization 11/1/2009 59 Female 152 lb 4/27/2010 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2010 59 Female 4/27/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 4/29/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2009 40 Female 240 lb 4/30/2010 Other Health Professional United States
Primary
Secondary
Urticaria Other Serious 2/1/2009 48 Male 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 4/6/2010 41 Female 5/7/2010 Other Health Professional Canada
Primary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 5/7/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 5/19/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2010 Female 5/26/2010 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 2/10/2010 77 Female 173 lb 5/26/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Legionella Hospitalization 6/26/2009 56 Male 160 lb 6/4/2010 Consumer United States
Primary
Concomitant
Pneumonia Legionella Hospitalization 6/14/2009 56 Male 160 lb 6/7/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/6/2009 57 Female 135 lb 6/3/2010 Consumer United States
Primary
Concomitant
Tuberculosis Other Serious 4/6/2010 41 Female 6/7/2010 Other Health Professional Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 43 Female 175 lb 6/16/2010 Consumer United States
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 4/15/2010 69 Male 176 lb 6/18/2010 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 5/4/2010 61 Female 6/18/2010 Other Health Professional Canada
Primary
Concomitant
Blood Glucose Increased Other Serious 5/25/2010 42 Female 6/18/2010 Consumer Canada
Primary
Concomitant
Pneumonia Legionella Hospitalization 6/14/2009 56 Male 160 lb 6/24/2010 Physician United States
Primary
Concomitant
Stress Cardiomyopathy Hospitalization 10/1/2009 77 Female 116 lb 6/29/2010 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 2/10/2010 77 Female 173 lb 6/29/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 3/13/2010 43 Female 180 lb 6/28/2010 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 74 Female 7/2/2010 Physician Canada
Primary
Secondary
Pneumonia Hospitalization 6/1/2010 50 Female 145 lb 7/9/2010 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 2/1/2010 59 Female 155 lb 7/16/2010 Physician United States
Primary
Concomitant
Polyp Hospitalization 6/1/2010 55 Female 210 lb 7/21/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 63 Female 165 lb 7/22/2010 Physician Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 4/6/2010 41 Female 7/22/2010 Other Health Professional Canada
Primary
Concomitant
Polyp Hospitalization 6/1/2010 55 Female 210 lb 7/22/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious Female 7/27/2010 Consumer Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious 6/1/2010 60 Female 158 lb 7/28/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 7/8/2010 68 Female 7/30/2010 Consumer Canada
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2010 53 Female 160 lb 8/2/2010 Consumer United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 7/2/2010 46 Female 180 lb 8/5/2010 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 6/1/2010 53 Female 170 lb 8/10/2010 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2010 27 Female 212 lb 8/13/2010 Consumer United States
Primary
Secondary
Malignant Melanoma Other Serious 6/1/2010 76 Female 135 lb 8/19/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/21/2010 48 Female 8/19/2010 Consumer Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/26/2010 22 Female 8/19/2010 Consumer Canada
Primary
Concomitant
Spinal Operation Other Serious 1/1/2010 45 Male 8/24/2010 Consumer United States
Primary
Concomitant
Troponin Increased Other Serious 8/6/2010 Female 99 lb 8/25/2010 Other Health Professional Slovenia
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 4/1/2010 62 Female 8/27/2010 Consumer United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 6/20/2010 84 Female 118 lb 8/27/2010 Physician Canada
Primary
Concomitant
Herpes Zoster Other Serious 8/21/2010 56 Female 8/25/2010 Pharmacist United States
Primary
Concomitant
Syphilis Hospitalization Female 109 lb 9/1/2010 Other Health Professional Germany
Primary
Concomitant
Therapeutic Response Decreased Other Serious 6/1/2010 60 Female 158 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2010 43 Female 9/20/2010 Consumer United States
Primary
Concomitant
Tonsillitis Other Serious 6/1/2010 58 Male 9/21/2010 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 9/4/2010 53 Female 130 lb 9/24/2010 Other Health Professional Denmark
Primary
Concomitant
Oropharyngeal Pain Other Serious 9/19/2010 63 Male 10/1/2010 Other Health Professional Canada
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 4/1/2010 62 Female 10/1/2010 Consumer United States
Primary
Secondary
Concomitant
Parotitis Hospitalization 8/30/2010 60 Female 119 lb 10/4/2010 Other Health Professional Colombia
Primary
Concomitant
Pneumonitis Life Threatening 9/4/2010 53 Female 130 lb 10/4/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/24/2010 63 Female 10/5/2010 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 9/15/2010 36 Female 10/6/2010 Consumer Canada
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2006 38 Female 10/7/2010 Consumer United States
Primary
Concomitant
Tuberculosis Other Serious 9/26/2010 76 Female 137 lb 10/8/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2010 43 Female 10/11/2010 Consumer United States
Primary
Concomitant
Lung Infection Hospitalization 9/19/2010 75 Female 163 lb 10/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/1/2010 50 Female 145 lb 10/12/2010 Physician United States
Primary
Concomitant
Abdominal Pain Hospitalization 9/28/2010 47 Male 194 lb 10/13/2010 Physician Mexico
Primary
Secondary
Otitis Media Acute Hospitalization 10/4/2010 45 Female 134 lb 10/13/2010 Other Health Professional Argentina
Primary
Concomitant
Abdominal Pain Hospitalization 9/30/2010 59 Male 174 lb 10/13/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 2/1/2009 48 Male 155 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/4/2010 53 Female 130 lb 10/21/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Syphilis Hospitalization 8/11/2010 Female 109 lb 10/21/2010 Other Health Professional Germany
Primary
Concomitant
Parotitis Hospitalization 8/30/2010 60 Female 119 lb 10/22/2010 Other Health Professional Colombia
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2010 63 Female 10/26/2010 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 6/1/2010 53 Female 170 lb 10/27/2010 Physician United States
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 4/1/2010 62 Female 10/27/2010 Consumer United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 9/26/2010 76 Female 137 lb 10/27/2010 Physician United States
Primary
Concomitant
Tachycardia Other Serious 9/24/2010 63 Female 10/27/2010 Physician United States
Primary
Concomitant
Enterocolitis Hospitalization 9/28/2010 47 Male 194 lb 10/29/2010 Physician Mexico
Primary
Secondary
Arthritis Bacterial Hospitalization 10/29/2010 54 Female 177 lb 11/3/2010 Physician Chile
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 10/13/2010 49 Female 126 lb 11/4/2010 Physician Peru
Primary
Concomitant
Pneumonia Hospitalization 10/24/2010 51 Female 11/5/2010 Consumer Canada
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 6/20/2010 84 Female 118 lb 11/5/2010 Physician Canada
Primary
Concomitant
Arthritis Bacterial Hospitalization 10/29/2010 54 Female 177 lb 11/11/2010 Physician Chile
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 9/28/2010 47 Male 194 lb 11/15/2010 Physician Mexico
Primary
Secondary
Pneumonitis Life Threatening 9/4/2010 53 Female 130 lb 11/18/2010 Physician Denmark
Primary
Secondary
Concomitant
Lung Infection Other Serious 9/19/2010 75 Female 163 lb 11/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 10/13/2010 49 Female 126 lb 11/19/2010 Physician Peru
Primary
Concomitant
Malignant Melanoma Other Serious 11/1/2010 56 Male 11/23/2010 Consumer Canada
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 10/1/2010 53 Female 11/23/2010 Physician United States
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 10/1/2010 53 Female 11/24/2010 Physician United States
Primary
Concomitant
Polyarthritis Hospitalization 10/29/2010 54 Female 177 lb 11/29/2010 Physician Chile
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 10/13/2010 49 Female 126 lb 11/29/2010 Physician Peru
Primary
Concomitant
Therapeutic Response Decreased Other Serious 6/1/2010 60 Female 158 lb 12/3/2010 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Hospitalization 9/30/2010 59 Male 174 lb 12/3/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Tuberculosis Other Serious 9/26/2010 76 Female 137 lb 12/3/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 4/24/2010 52 Male 397 lb 12/3/2010 Other Health Professional Australia
Primary
Concomitant
Otitis Media Acute Hospitalization 10/4/2010 45 Female 134 lb 12/3/2010 Other Health Professional Argentina
Primary
Concomitant
Purpura 84 Female 118 lb 12/8/2010 Physician Canada
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 11/10/2010 66 Female 170 lb 12/10/2010 Physician Denmark
Primary
Concomitant
Sensation Of Heaviness Other Serious 6/1/2010 53 Female 170 lb 12/10/2010 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 11/3/2010 60 Female 143 lb 12/10/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 11/11/2010 77 Female 158 lb 12/10/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Drug Dose Omission Hospitalization 7/15/2010 65 Female 160 lb 12/10/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2010 63 Female 12/17/2010 Other Health Professional Australia
Primary
Concomitant
Lobar Pneumonia Other Serious 11/27/2010 57 Male 185 lb 12/20/2010 Physician United Kingdom
Primary
Concomitant
Rash Other Serious 12/1/2009 57 Male 142 lb 12/20/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 9/25/2010 47 Male 12/23/2010 Physician Germany
Primary
Concomitant
Gastrointestinal Inflammation Hospitalization 10/1/2010 53 Female 160 lb 1/6/2011 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 10/13/2010 59 Female 1/12/2011 Consumer United States
Primary
Concomitant
Crohn's Disease Other Serious Male 229 lb 1/20/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 11/10/2010 66 Female 170 lb 1/20/2011 Physician Denmark
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 4/24/2010 52 Male 397 lb 1/28/2011 Other Health Professional Australia
Primary
Concomitant
Hypoaesthesia Facial Female 135 lb 1/29/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2011 70 Female 214 lb 2/1/2011 Physician Canada
Primary
Concomitant
Intestinal Perforation Hospitalization 10/1/2010 53 Female 160 lb 2/4/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 1/1/2010 61 Male 190 lb 2/11/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/10/2010 66 Female 170 lb 2/11/2011 Physician Denmark
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 10/19/2010 58 Female 155 lb 2/15/2011 Consumer United States
Primary
Concomitant
Arthropathy Hospitalization 4/1/2010 64 Female 112 lb 2/17/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious Female 2/17/2011 Physician Canada
Primary
Concomitant
Cerebral Haemorrhage Other Serious 2/1/2011 74 Female 2/17/2011 Other Health Professional Netherlands
Primary
Concomitant
Influenza Hospitalization 4/24/2010 52 Male 397 lb 2/25/2011 Other Health Professional Australia
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 8/1/2010 70 Female 160 lb 2/25/2011 Consumer United States
Primary
Concomitant
Tooth Infection Hospitalization 2/6/2011 45 Female 2/25/2011 Other Health Professional Australia
Primary
Concomitant
Swelling Other Serious 12/31/2010 48 Female 2/25/2011 Consumer United States
Primary
Concomitant
Pneumococcal Infection Life Threatening 1/3/2011 56 Female 121 lb 2/25/2011 Physician Denmark
Primary
Concomitant
Tympanic Membrane Perforation Other Serious 1/1/2011 50 Male 2/28/2011 Other Health Professional Sweden
Primary
Concomitant
Retinal Detachment Hospitalization 2/1/2011 56 Female 3/4/2011 Other Health Professional Canada
Primary
Concomitant
Leukopenia Other Serious 12/28/2010 60 Female 3/11/2011 Physician Italy
Primary
Secondary
Concomitant

Drug Data