Dexamethasone combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Respiratory Failure Death 7/13/2005 57 Female 159 lb 1/13/2006 Physician Germany
Primary
Concomitant
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Vomiting Other Serious 1/19/2006 Female 125 lb 1/26/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/22/2005 Female 138 lb 1/23/2006 United States
Primary
Secondary
Therapy Non-responder Death Female 1/27/2006 United Kingdom
Primary
Secondary
Vomiting Death Female 1/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Steroid Withdrawal Syndrome Hospitalization 13 Male 1/27/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 8/1/2005 10 Male 67 lb 1/31/2006 Pharmacist United States
Primary
Concomitant
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
Pyrexia Hospitalization Male 2/16/2006 Physician United States
Primary
Concomitant
Papilloedema Required Intervention Unknown 2/16/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 60 Female 2/28/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/22/2006 Female 77 lb 2/24/2006 United States
Primary
Secondary
Blood Pressure Decreased Death 2/13/2005 64 Male 223 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Disability 18 Male 3/15/2006
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 48 Female 3/15/2006
Primary
Concomitant
Paraesthesia Required Intervention 3/18/2006 Female 90 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Required Intervention 3/20/2006 Female 40 lb 3/23/2006 United States
Primary
Secondary
Transverse Sinus Thrombosis Hospitalization 12/9/2005 Female 43 lb 4/4/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Required Intervention 6/20/2005 18 Female 4/5/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 54 Male 4/5/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/3/2006 Male 23 lb 4/12/2006 United States
Primary
Secondary
Pyrexia Hospitalization 2/17/2006 5 Female 39 lb 4/10/2006 Other Health Professional Canada
Primary
Concomitant
Visual Acuity Reduced Required Intervention 6/20/2005 18 Female 4/17/2006 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 12/1/2005 3 Male 5/5/2006 Physician France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 57 Male 5/9/2006 Australia
Primary
Concomitant
Wound Drainage Hospitalization 4/24/2006 Male 21 lb 4/27/2006 United States
Primary
Secondary
Urinary Incontinence Hospitalization 3/1/1997 16 Male 5/1/2006 Physician Spain
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Plasmacytoma Other Serious 3/1/2002 Female 5/30/2006 Physician Japan
Primary
Secondary
Thrombosis Hospitalization 1/1/2003 62 Female 7/13/2006 Consumer Australia
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 36 Female 7/14/2006 Other Health Professional Turkey
Primary
Secondary
Insulin-like Growth Factor Decreased Other Serious 15 Male 122 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 7/31/2006 Male 168 lb 8/1/2006 United States
Primary
Secondary
Weight Decreased Other Serious 4/1/2006 73 Male 201 lb 8/18/2006 United States
Primary
Concomitant
Vomiting Hospitalization 8/14/2006 Female 180 lb 8/15/2006 United States
Primary
Secondary
Concomitant
Fungal Infection Death 10/2/2006 Physician United States
Primary
Concomitant
Mucormycosis Death 10/2/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2005 7 Female 10/26/2006 United Kingdom
Primary
Secondary
Vomiting Hospitalization 9/15/2006 Male 29 lb 11/6/2006 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization Female 87 lb 11/9/2006 United States
Primary
Secondary
Concomitant
Thrombosis 9/29/2006 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/23/2006 Female 40 lb 11/27/2006 Other Health Professional United States
Primary
Secondary
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 12/7/2006 Physician Australia
Primary
Secondary
Weight Increased Hospitalization 11/23/2006 Female 40 lb 11/30/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 10/18/2006 Female 87 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/10/2006 Female 100 lb 12/13/2006 United States
Primary
Secondary
Vaginal Ulceration Hospitalization 11/27/2006 Female 188 lb 12/12/2006 United States
Primary
Secondary
Concomitant
Rash 11/10/2005 Male 260 lb 12/21/2006 Other Health Professional United States
Primary
Concomitant
Listeria Sepsis Other Serious 10/24/2006 Male 192 lb 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vulval Erythema Hospitalization 12/10/2006 Female 138 lb 12/18/2006 United States
Primary
Secondary
Ventricular Tachycardia Hospitalization 12/14/2006 Female 140 lb 12/18/2006 United States
Primary
Secondary
Pancreatitis Other Serious 10/20/2006 17 Female 112 lb 12/18/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/23/2006 Female 40 lb 12/18/2006 United States
Primary
Secondary
Systemic Inflammatory Response Syndrome Hospitalization 12/26/2002 1 Male 26 lb 12/22/2006 United States
Primary
Secondary
Vulval Disorder Hospitalization 12/10/2006 Female 138 lb 12/21/2006 United States
Primary
Secondary
Neurotoxicity Other Serious 15 Female 10/7/2006 United States
Primary
Concomitant
Hepatotoxicity Other Serious 52 Male 1/19/2007 Other Health Professional Israel
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/10/2006 Female 100 lb 1/12/2007 United States
Primary
Secondary
Hepatotoxicity Other Serious 47 Female 1/19/2007 Other Health Professional Israel
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 52 Male 1/18/2007 Physician Israel
Primary
Secondary
Concomitant
Tracheal Haemorrhage 12/22/2006 Female 43 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 70 Female 2/12/2007 Consumer Israel
Primary
Secondary
Concomitant
Liver Disorder Other Serious 52 Male 2/7/2007 Israel
Primary
Secondary
White Blood Cell Count Increased Hospitalization 11/11/2006 68 Female 2/9/2007 Brazil
Primary
Secondary
Concomitant
Heart Rate Abnormal Disability 2/16/2006 43 Female 2/17/2007 Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 2/20/2007 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 2/20/2007 Consumer Australia
Primary
Secondary
Jaundice Cholestatic Other Serious 52 Male 2/23/2007
Primary
Secondary
Hepatotoxicity Other Serious 47 Female 2/23/2007
Primary
Secondary
Sinusitis Fungal Hospitalization 2/22/2007 Male 227 lb United States
Primary
Secondary
Thrombocytopenia Other Serious 2/22/2007 Australia
Primary
Secondary
Stem Cell Transplant Death Unknown 2/22/2007 Australia
Primary
Secondary
Pneumonia Hospitalization 11/11/2006 68 Female 2/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Uv Light Therapy Other Serious 49 Male 3/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 26 Female 3/7/2007 Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 25 Male 3/7/2007 Australia
Primary
Secondary
Concomitant
Somnolence Other Serious 13 Male 3/14/2007 Japan
Primary
Secondary
White Blood Cell Count Decreased 3/7/2007 Female 66 lb 3/9/2007 United States
Primary
Secondary
Recall Phenomenon 49 Male 3/15/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 49 Male 3/19/2007
Primary
Secondary
White Blood Cell Count Decreased Female 66 lb 3/20/2007 United States
Primary
Secondary
Vulval Ulceration Hospitalization 11/27/2006 Female 188 lb 3/20/2007 United States
Primary
Secondary
Concomitant
Wound Other Serious 8/14/2006 Female 137 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Listeria Encephalitis Life Threatening 9/7/2005 Female 112 lb 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2005 56 Female 270 lb 3/31/2006 United States
Primary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2007 Physician United States
Primary
Concomitant
Neutrophil Count Decreased 7/24/2006 21 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Spinal Cord Disorder Other Serious 25 Male 4/4/2007 Other Health Professional Australia
Primary
Secondary
Spinal Cord Disorder Other Serious 26 Female 4/4/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Influenza Hospitalization 3/26/2007 Female 86 lb 4/3/2007 United States
Primary
Secondary
Meningitis Aseptic Other Serious 3/10/2007 59 Female 4/9/2007 Physician Switzerland
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 25 Male 4/10/2007 Other Health Professional Australia
Primary
Secondary
Spinal Cord Disorder Other Serious 26 Female 4/10/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Spinal Cord Disorder Hospitalization 25 Male 4/11/2007 Australia
Primary
Secondary
Sepsis Death 25 Male 4/11/2007
Primary
Secondary
Sepsis Death 26 Female 4/11/2007
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 26 Female 4/11/2007 Australia
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 25 Male 4/13/2007 Consumer United States
Primary
Secondary
Spinal Cord Disorder Hospitalization 26 Female 4/13/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 5/1/2006 72 Female 146 lb 4/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 26 Female 4/6/2007 Other Health Professional Australia
Primary
Secondary
Respiratory Arrest 4/9/2007 Female 30 lb 4/9/2007 United States
Primary
Secondary
Sepsis Other Serious 25 Male 4/6/2007 Other Health Professional Australia
Primary
Secondary
Tachycardia Other Serious 2/16/2005 17 Male 4/20/2007 Physician Malaysia
Primary
Secondary
Hyperglycaemia Other Serious 2/17/2006 9 Female 3/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/15/2007 Male 220 lb 6/26/2007 United States
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Polyneuropathy Other Serious Male 7/5/2007
Primary
Secondary
Renal Failure Acute Hospitalization 6/6/2007 Male 200 lb 9/14/2007 United States
Primary
Secondary
Sepsis Death 7/3/2007 Female 9/25/2007 Physician Greece
Primary
Secondary
Concomitant
Hepatitis B Death 54 Male 9/25/2007 Physician Japan
Primary
Concomitant
Respiratory Disorder Hospitalization 9/17/2007 Male 34 lb 10/2/2007 United States
Primary
Secondary
Bladder Perforation Hospitalization 10/13/2007 Female 98 lb 10/16/2007 United States
Primary
Secondary
No Therapeutic Response Other Serious 52 Male 10/26/2007 Israel
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 9/17/2007 Male 34 lb 10/29/2007 United States
Primary
Secondary
Flatulence Hospitalization 10/13/2007 Female 98 lb 10/29/2007 United States
Primary
Secondary
Systemic Candida Other Serious 26 Male 11/8/2007 Other Health Professional Germany
Primary
Secondary
Hepatitis B Death 54 Male 11/8/2007 Physician Japan
Primary
Concomitant
Speech Disorder Developmental Other Serious Female 11/5/2007 Japan
Primary
Secondary
Post Procedural Haemorrhage Disability 47 Male 11/7/2007 Physician United States
Primary
Concomitant
Toxic Encephalopathy Other Serious 32 Female 11/21/2007 Other Health Professional Germany
Primary
Secondary
Spinal Compression Fracture Other Serious 7/17/2007 Male 218 lb 11/21/2007 United Kingdom
Primary
Concomitant
Toxic Encephalopathy Other Serious 32 Female 11/28/2007 Other Health Professional Germany
Primary
Secondary
Toxic Encephalopathy Other Serious 32 Female 12/3/2007 Consumer United States
Primary
Secondary
Grand Mal Convulsion Death 32 Female 12/3/2007
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 37 Male 12/20/2007 Physician Turkey
Primary
Concomitant
Stress Other Serious 28 Male 12/14/2007 Australia
Primary
Secondary
Mucosal Inflammation Hospitalization 37 Male 12/28/2007 Physician Turkey
Primary
Concomitant
White Blood Cell Count Decreased Death 4 Male 3/18/2008 Physician Switzerland
Primary
Secondary
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Neurotoxicity Other Serious 35 Female 3/27/2008 Pharmacist United States
Primary
Concomitant

Drug Data