Idarubicin Hcl combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neurotoxicity Death 36 Female 1/4/2006 Consumer Japan
Primary
Secondary
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Leukoencephalopathy Death 36 Female 1/26/2006 Consumer Japan
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Drug Toxicity Death Unknown 1/25/2006 United States
Primary
Secondary
Weight Decreased Death 6 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6 Female 1/28/2006 Physician United States
Primary
Secondary
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
T-cell Lymphoma Hospitalization 36 Female 3/17/2006 Physician Turkey
Primary
Secondary
Stupor Death 36 Female 3/24/2006 Turkey
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 36 Female 7/14/2006 Other Health Professional Turkey
Primary
Secondary
Myelodysplastic Syndrome Other Serious 26 Female 8/16/2006 Physician United States
Primary
Secondary
Skin Ulcer Hospitalization 67 Female 10/18/2006 Other Health Professional France
Primary
Secondary
Skin Ulcer Hospitalization 67 Female 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 6/1/2006 66 Female 2/27/2007 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 25 Male 3/7/2007 Australia
Primary
Secondary
Concomitant
Sepsis Death 25 Male 3/22/2007 Australia
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Hospitalization 66 Female 4/3/2007
Primary
Secondary
Spinal Cord Disorder Other Serious 25 Male 4/4/2007 Other Health Professional Australia
Primary
Secondary
White Blood Cell Morphology Abnormal Other Serious 51 Female 3/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 25 Male 4/10/2007 Other Health Professional Australia
Primary
Secondary
Spinal Cord Disorder Hospitalization 25 Male 4/11/2007 Australia
Primary
Secondary
Sepsis Death 25 Male 4/11/2007
Primary
Secondary
Spinal Cord Disorder Other Serious 25 Male 4/13/2007 Consumer United States
Primary
Secondary
Sepsis Other Serious 25 Male 4/6/2007 Other Health Professional Australia
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
Stem Cell Transplant Other Serious 51 Female 5/8/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 36 Female 5/25/2007 Physician Turkey
Primary
Secondary
Infection Death 6/5/2007 United States
Primary
Secondary
Infection Death 6/5/2007 United States
Primary
Secondary
Infection Death 6/5/2007 United States
Primary
Secondary
Infection Death 6/5/2007 United States
Primary
Secondary
Infection Death 6/5/2007 United States
Primary
Secondary
Venous Haemorrhage Death 42 Male 6/1/2007 Greece
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 25 Male 6/14/2007 Physician Australia
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Other Serious 8 Male 6/28/2007 Other Health Professional Australia
Primary
Secondary
Parakeratosis Other Serious 8/1/2004 53 Male 11/20/2007 Consumer United States
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Stem Cell Transplant Other Serious 25 Male 1/15/2008 Australia
Primary
Secondary
Wheezing Death 1/19/2008 49 Male 154 lb 2/8/2008 Physician France
Primary
Secondary
Pancreatitis Acute Hospitalization 21 Male 2/21/2008 France
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 17 Male 3/19/2008 Physician India
Primary
Secondary
Pneumonia Fungal Life Threatening 3/25/2008 India
Primary
Secondary
Concomitant
Pneumonia Fungal Life Threatening 3/26/2008 India
Primary
Secondary
Concomitant
Aspergillosis Death 1/20/2008 Male 4/2/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 4/1/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 5/12/2008 Other Health Professional Turkey
Primary
Secondary
Vomiting Other Serious 29 Female 5/14/2008 Other Health Professional Turkey
Primary
Secondary
Pneumonia Bacterial Other Serious 4/9/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 4/9/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Panniculitis Other Serious 29 Female 5/27/2008 Turkey
Primary
Secondary
Concomitant
Death Death 73 6/12/2008 Other Health Professional Spain
Primary
Secondary
Chronic Myelomonocytic Leukaemia Other Serious 41 Male 7/3/2008 Tunisia
Primary
Secondary
Lung Disorder Hospitalization 7/3/2008 80 Male 168 lb 7/14/2008 Physician France
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 Male 7/30/2008 Physician United Kingdom
Primary
Secondary
Panniculitis Other Serious 29 Female 7/18/2008 Turkey
Primary
Secondary
Lymphoma Hospitalization 7/3/2008 80 Male 168 lb 8/1/2008 Physician France
Primary
Secondary
Concomitant
Neoplasm Recurrence Hospitalization 7/30/2008 80 Male 168 lb 9/17/2008 Physician France
Primary
Secondary
Concomitant
Wrong Drug Administered Life Threatening 9/19/2008 71 Male 9/23/2008 Physician Italy
Primary
Concomitant
Fungal Rhinitis Other Serious 41 Male 7/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 44 Female 9/29/2008 Japan
Primary
Secondary
Chronic Myelomonocytic Leukaemia Other Serious 41 Male 10/21/2008
Primary
Secondary
Somnolence Life Threatening 9/19/2008 71 Male 10/29/2008 Physician Italy
Primary
Concomitant
Incorrect Route Of Drug Administration Life Threatening 9/19/2008 71 Male 11/6/2008 Physician Italy
Primary
Concomitant
Sepsis Hospitalization 53 Female 11/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 9/19/2008 71 Male 11/24/2008 Physician Italy
Primary
Concomitant
Skin Ulcer Other Serious 29 Female 12/3/2008 Other Health Professional Greece
Primary
Concomitant
Vasculitis Hospitalization 6/1/2007 53 Female 12/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Drug Administered Life Threatening 9/19/2008 71 Male 12/4/2008 Physician Italy
Primary
Concomitant
Sepsis Hospitalization 1/1/2007 53 Female 12/24/2008
Primary
Secondary
Wrong Drug Administered Life Threatening 9/18/2008 71 Male 12/19/2008 Physician Italy
Primary
Concomitant
Wrong Drug Administered Life Threatening 9/18/2008 71 Male 12/22/2008 Physician Italy
Primary
Concomitant
Rhabdomyolysis Other Serious 10/24/2008 2 Male 27 lb 3/18/2009 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Graft Versus Host Disease Other Serious 17 Male 4/15/2009 Other Health Professional India
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Renal Failure Acute Other Serious 54 Male 5/11/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 54 Male 5/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2007 54 Male 5/22/2009 Physician Spain
Primary
Secondary
Concomitant
Psoriasis Hospitalization 4/3/2009 56 Male 6/12/2009 France
Primary
Secondary
Hepatic Function Abnormal Other Serious 65 Male 8/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4 Female 8/20/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4 Female 8/28/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Grand Mal Convulsion Life Threatening 7/5/2008 14 Male 101 lb 9/14/2009 Physician Poland
Primary
Secondary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/21/2009 Physician Poland
Primary
Secondary
Concomitant
Procedural Complication Required Intervention 55 Female 10/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 55 Female 12/17/2009 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 50 Male 1/15/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 16 Female 1/15/2010 Other Health Professional Australia
Primary
Secondary
Stem Cell Transplant Other Serious 29 Female 1/15/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Death 54 Male 1/15/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 50 Male 1/15/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 43 Male 1/15/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 37 Female 1/15/2010 Physician Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 30 Female 1/15/2010 Other Health Professional Australia
Primary
Secondary
Stenotrophomonas Infection Other Serious 10/5/2006 35 Female 1/25/2010
Primary
Secondary
Concomitant
Liver Disorder Other Serious 60 Male 1/15/2010 Other Health Professional Australia
Primary
Secondary
Unresponsive To Stimuli Death 1 Male 2/17/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Cytogenetic Abnormality Other Serious 30 Female 2/19/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Death 54 Male 2/19/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 43 Male 2/19/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 60 Male 2/19/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 50 Male 2/19/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 29 Female 2/19/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 16 Female 2/19/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 37 Female 2/19/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Death 50 Male 2/19/2010 Other Health Professional Australia
Primary
Secondary
Respiratory Alkalosis Life Threatening 1 Male 2/22/2010 Taiwan, Province Of China
Primary
Secondary
Hyperammonaemic Encephalopathy Life Threatening 1 Male 2/24/2010
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Other Serious Male 3/1/2010 Physician Taiwan, Province Of China
Primary
Secondary
Respiratory Alkalosis Hospitalization 1 Male 3/2/2010 Taiwan, Province Of China
Primary
Secondary
Unresponsive To Stimuli Death 1 Male 3/19/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Myelodysplastic Syndrome Other Serious 50 Male 5/24/2010 Other Health Professional Australia
Primary
Secondary
Hepatic Function Abnormal Other Serious 16 Female 5/24/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 37 Female 5/24/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 30 Female 5/24/2010 Other Health Professional Australia
Primary
Secondary
Cytogenetic Abnormality Other Serious 43 Male 5/24/2010 Other Health Professional Australia
Primary
Secondary
Hepatic Function Abnormal Other Serious 60 Male 5/24/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Death 50 Male 5/26/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 29 Female 5/28/2010 Other Health Professional Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 54 Male 5/28/2010 Other Health Professional Australia
Primary
Secondary
Tumour Lysis Syndrome Other Serious 4 Male 6/22/2010 Other Health Professional Japan
Primary
Secondary
Weight Decreased Death 10/1/2009 74 Male 9/16/2010 Consumer France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 21 Female 9/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 21 Female 9/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death Male 9/20/2010 Other Health Professional Spain
Primary
Secondary
Myelodysplastic Syndrome Other Serious Male 9/20/2010 Other Health Professional Spain
Primary
Secondary
Myelodysplastic Syndrome Death Female 9/20/2010 Other Health Professional Spain
Primary
Secondary
Myelodysplastic Syndrome Other Serious Female 9/20/2010 Physician Spain
Primary
Secondary
Acute Myeloid Leukaemia Death Female 9/20/2010 Other Health Professional Spain
Primary
Secondary
Drug Toxicity Other Serious Female 9/21/2010 Other Health Professional Spain
Primary
Secondary
Myelodysplastic Syndrome Other Serious Female 9/22/2010 Other Health Professional Spain
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Male 9/22/2010 Other Health Professional Spain
Primary
Secondary
Metastatic Renal Cell Carcinoma Other Serious 58 Male 10/28/2010 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 21 Female 11/5/2010 Other Health Professional Germany
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 9 Female 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 9 Female 12/28/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 9/16/2009 9 Female 1/31/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiopulmonary Failure Death 1 Male 3/1/2011 Physician Taiwan, Province Of China
Primary
Secondary
Bronchiectasis Hospitalization 35 Male 3/30/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Fungal Other Serious 34 Female 3/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Aplasia Other Serious 34 Female 4/21/2011 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data