Methotrexate combined with Paxil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Basal Cell Carcinoma Other Serious 8/1/2005 Female 220 lb 1/3/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious Female 155 lb 1/3/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Other Serious 5/1/2002 48 Male 190 lb 1/10/2006 Lawyer United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 12/12/2005 54 Female 125 lb 1/6/2006 Physician United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 1/13/2006 Physician United States
Primary
Concomitant
Tongue Disorder Hospitalization 9/28/2005 75 Female 115 lb 11/19/2005 Pharmacist United States
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2005 Female 128 lb 1/27/2006 Physician United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 2/3/2006 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 11/16/2002 17 Female 125 lb 2/7/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction 2/8/2006 Consumer United States
Primary
Secondary
Disseminated Tuberculosis Other Serious 12/1/2004 Female 160 lb 2/13/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2000 67 Male 154 lb 2/17/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/19/2002 41 Female 150 lb 3/1/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 12/12/2005 54 Female 125 lb 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2001 41 Female 150 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 12/12/2005 54 Female 125 lb 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 4/12/2006 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2000 46 Female 4/27/2006 Consumer United States
Primary
Concomitant
Adenocarcinoma Other Serious 5/5/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Male 5/25/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2006 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation 6/1/2005 62 Male 150 lb 4/3/2006 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 5/19/2006 Female 6/21/2006 Other Health Professional United States
Primary
Concomitant
Burning Sensation 4/3/2006 62 Female 110 lb 6/30/2006 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 7/20/2006 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 8/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 4/29/2003 Female 8/10/2006 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 8/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sedation Other Serious 1/1/2005 Female 8/18/2006 Consumer
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2000 46 Female 9/6/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2000 46 Female 9/8/2006 Consumer United States
Primary
Concomitant
Sudden Death Other Serious 7/1/2006 67 Female 9/1/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 7/1/2006 67 Female 10/9/2006 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2000 46 Female 10/19/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 150 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 52 Female 10/27/2006 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 8/1/2000 46 Female 11/9/2006 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 10/1/2004 52 Female 147 lb 11/6/2006 United States
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Bruising 7/1/2006 Female 12/18/2006 Physician United States
Primary
Concomitant
Pruritus 5/25/2006 51 Female 168 lb 12/22/2006 Consumer United States
Primary
Concomitant
Viral Myocarditis Death 9/21/2006 41 Female 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Cancer Metastatic Death 3/10/2005 Female 2/1/2007 Physician United States
Primary
Concomitant
Progesterone Receptor Assay Positive Other Serious 12/12/2005 54 Female 125 lb 3/6/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/21/2006 41 Female 123 lb 3/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Benign Intracranial Hypertension Other Serious 1/1/2006 15 Female 150 lb 3/21/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 11/16/2002 17 Female 125 lb 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 1/1/2005 66 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Other Serious 12/1/2005 Female 187 lb 5/24/2007 Consumer Canada
Primary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Intention Tremor 1/13/2007 75 Female 5/7/2007 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 4/29/2003 Female 7/23/2007 Physician Canada
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 3/7/2007 Male 163 lb 8/13/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Small Cell Lung Cancer Metastatic Other Serious 1/1/2004 Female 205 lb 8/13/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Death Death 9/10/2007 Female 9/19/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal 49 Female 9/19/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Death 5/1/2007 Female 110 lb 10/23/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/14/2007 Consumer United States
Primary
Concomitant
Radiotherapy Other Serious 1/31/2001 1 Female 150 lb 9/17/2007 Lawyer United States
Primary
Secondary
Concomitant
Nausea 1/1/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Sinus Disorder 1/1/2006 57 Female 214 lb 12/21/2007 Consumer United States
Primary
Concomitant
Diverticulitis Hospitalization 8/22/2007 Female 226 lb 12/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/22/2007 Female 226 lb 1/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 53 Female 250 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 1/22/2008 Physician Japan
Primary
Concomitant
Scleritis Other Serious 11/15/2006 Female 2/4/2008 Physician United States
Primary
Concomitant
Pyoderma Gangrenosum Hospitalization 11/1/2007 Female 121 lb 2/11/2008 Physician Japan
Primary
Concomitant
Diverticulitis Hospitalization 8/22/2007 Female 226 lb 2/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Scleritis Other Serious 11/15/2006 Female 2/29/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 6/13/2006 74 Male 198 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 9/21/2007 5/13/2008 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 75 Female 4/24/2008 Physician United States
Primary
Secondary
Concomitant
Paranasal Sinus Hypersecretion 1/1/2007 57 Female 214 lb 6/30/2008 Physician United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 6/8/2008 Male 141 lb 7/1/2008 Physician United States
Primary
Concomitant
Death Hospitalization 6/8/2008 Male 141 lb 7/18/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/26/2008 Female 8/6/2008 Physician United States
Primary
Secondary
Concomitant
Balance Disorder 6/1/2007 70 Male 8/5/2008 Consumer United States
Primary
Concomitant
Peritonitis Other Serious 1/1/2008 61 Female 8/7/2008 Consumer Canada
Primary
Concomitant
Traumatic Brain Injury Other Serious 11/7/2007 Female 234 lb 9/12/2008 Physician United States
Primary
Concomitant
Coronary Artery Disease Other Serious 9/12/2006 Female 139 lb 10/16/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 Female 140 lb 10/25/2008 Physician United States
Primary
Concomitant
Application Site Irritation 8/12/2008 59 Female 11/10/2008 Consumer United States
Primary
Concomitant
Infected Bites 11/22/2007 Female 176 lb 11/17/2008 Physician United States
Primary
Concomitant
Nasopharyngitis 12/1/2007 Female 150 lb 12/1/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 11/1/2006 Female 185 lb 12/8/2008 Physician United States
Primary
Concomitant
Herpes Virus Infection Female 184 lb 12/11/2008 Physician
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 140 lb 12/11/2008 Physician United States
Primary
Concomitant
Skin Fragility 11/22/2007 Female 176 lb 12/18/2008 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 12/2/2008 57 Male 150 lb 1/7/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Histoplasmosis Disseminated Hospitalization 6/10/2002 46 Female 239 lb 2/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Injection Site Pain Male 182 lb 3/14/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 Female 142 lb 4/20/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/28/2008 Female 5/22/2009 Physician United States
Primary
Secondary
Concomitant
Insomnia 11/13/2008 30 Female 140 lb 5/18/2009 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 4/17/2009 Female 126 lb 6/5/2009 United States
Primary
Concomitant
Infected Cyst 1/1/2008 Male 172 lb 6/11/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2009 Female 142 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Migraine 3/1/2009 54 Female 6/22/2009 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 12/2/2008 57 Male 150 lb 7/13/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/19/2006 9 Male 51 lb 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 6/25/2009 Female 125 lb 7/28/2009 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iiib Other Serious 4/17/2009 Female 126 lb 9/18/2009 United States
Primary
Concomitant
Drug Dose Omission 6/1/2009 Male 256 lb 9/18/2009 United States
Primary
Concomitant
Drug Dose Omission 6/23/2009 Female 115 lb 9/19/2009 United States
Primary
Concomitant
Vomiting 6/1/2009 Female 240 lb 9/19/2009 United States
Primary
Secondary
Concomitant
Vomiting 1/1/2006 Female 165 lb 9/19/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/7/2009 Female 175 lb 9/19/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2008 61 Male 143 lb 9/21/2009 Lawyer United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 1/1/2007 Female 10/2/2009 United States
Primary
Concomitant
Venous Insufficiency Hospitalization 82 Male 10/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2008 Male 238 lb 11/9/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/4/2009 Lawyer United States
Primary
Concomitant
Dyspepsia Other Serious 7/1/2008 Male 331 lb 11/19/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/30/2009 Consumer United States
Primary
Concomitant
Metastases To Lymph Nodes Other Serious Female 132 lb 12/3/2009 Other Health Professional Canada
Primary
Concomitant
Malabsorption From Injection Site 8/1/2009 50 Female 185 lb 10/30/2009 Consumer United States
Primary
Concomitant
Sepsis Other Serious 12/27/2007 61 Female 163 lb 12/17/2009 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 6/1/2008 61 Male 143 lb 12/17/2009 Lawyer United States
Primary
Secondary
Concomitant
Oedema Peripheral 86 Female 190 lb 12/21/2009 Consumer United States
Primary
Concomitant
Skin Lesion Other Serious 57 Male 150 lb 1/14/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Vein Disorder Other Serious 1/1/2004 Female 258 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor 1/1/2007 Female 250 lb 1/29/2010 United States
Primary
Concomitant
Drug Ineffective 1/1/2009 Male 230 lb 1/29/2010 Other Health Professional United States
Primary
Concomitant
Sensation Of Pressure 9/1/2009 195 lb 1/29/2010 United States
Primary
Concomitant
Paranasal Sinus Hypersecretion 11/6/2009 Female 160 lb 1/30/2010 United States
Primary
Concomitant
Pharyngeal Mass Other Serious 3/1/2009 Female 202 lb 2/8/2010 United States
Primary
Concomitant
Pharyngeal Mass Other Serious 3/1/2009 Female 202 lb 2/16/2010 United States
Primary
Concomitant
Spinal Column Stenosis Other Serious Female 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 1/1/2004 Female 258 lb 2/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Pain 1/1/2009 Female 2/22/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 12/26/1998 Female 150 lb 2/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 7/1/2005 Female 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/3/2010 Female 90 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Interacting
Walking Aid User Other Serious 1/9/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Metastases To Lymph Nodes Other Serious Female 132 lb 3/30/2010 Other Health Professional Canada
Primary
Concomitant
Respiratory Failure Hospitalization 5/28/2008 Female 142 lb 3/30/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/3/2010 61 Female 90 lb 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Interacting
Walking Aid User Other Serious 1/9/2004 69 Female 4/9/2010 Physician United States
Primary
Concomitant
Tongue Neoplasm Other Serious 3/1/2009 58 Female 202 lb 4/15/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 4/19/2010 Physician United States
Primary
Concomitant

Drug Data