Glucophage combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Death Death 6/3/2005 1/2/2006 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Hospitalization 9/1/2005 63 Female 1/5/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/1998 58 Female 196 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Sciatica Hospitalization 9/1/2005 63 Female 1/17/2006 United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 2/9/2006 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 6/8/2004 Male 123 lb 2/15/2006 France
Primary
Concomitant
Pneumonia Hospitalization 1/1/2000 67 Male 154 lb 2/17/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 66 Male 201 lb 3/14/2006 Lawyer United States
Primary
Concomitant
Retinal Vein Occlusion Other Serious 5/1/2005 Female 3/21/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Swelling Other Serious 1/1/2006 56 Female 287 lb 3/27/2006 Physician Switzerland
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 66 Male 201 lb 4/6/2006 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 1/24/2006 56 Female 287 lb 4/20/2006 Physician Switzerland
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/1999 60 Female 201 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Death Female 6/12/2006 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/24/2006 52 Female 7/6/2006 Other Health Professional United States
Primary
Concomitant
Diverticulitis Hospitalization 12/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Weight Decreased 2/1/2006 48 Female 295 lb 4/17/2006 Consumer United States
Primary
Concomitant
Respiratory Distress Other Serious 9/10/2005 42 Female 144 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Haemorrhage Hospitalization 12/1/2004 60 Male 249 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 4/20/2006 Female 148 lb 8/10/2006 Physician United States
Primary
Concomitant
Gastritis Hospitalization 6/1/2006 Female 174 lb 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/8/2006 Other Health Professional United States
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/14/2006 Other Health Professional United States
Primary
Concomitant
Diverticulitis Hospitalization 12/19/2005 Male 9/6/2006 Physician United States
Primary
Concomitant
Weight Loss Diet Hospitalization 1/1/2006 46 Female 248 lb 8/29/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 9/21/2006 Other Health Professional United States
Primary
Concomitant
Obstruction Other Serious 6/28/2006 Female 205 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastritis Hospitalization 6/1/2006 Female 174 lb 10/2/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/24/2006 52 Female 10/2/2006 Other Health Professional United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 4/1/2006 Female 10/13/2006 Physician United States
Primary
Concomitant
Skin Infection Hospitalization 5/1/2005 Female 305 lb 10/19/2006 Physician United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Other Serious 4/1/2006 Female 11/3/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious Female 205 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 65 Female 174 lb 11/10/2006 Consumer United States
Primary
Concomitant
Depression Suicidal Other Serious 9/1/2006 65 Female 174 lb 1/11/2007 Physician United States
Primary
Concomitant
Weight Decreased 8/31/2006 71 Female 230 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Increased 9/8/2006 70 Male 216 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pericarditis Hospitalization 2/18/2007 42 Male 317 lb 3/7/2007 Physician Greece
Primary
Concomitant
Splenomegaly Other Serious 2/24/2007 51 Male 300 lb 3/8/2007 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/13/2007 Male 165 lb 3/24/2007 Consumer United States
Primary
Concomitant
Bronchitis Other Serious Female 250 lb 4/5/2007 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 7/1/2006 Female 4/6/2007 Physician United States
Primary
Concomitant
Toothache Other Serious 1/25/2005 41 Female 244 lb 7/16/2007 United States
Primary
Secondary
Concomitant
Subdural Haematoma Evacuation Life Threatening 7/3/2007 65 Female 163 lb 9/8/2007 France
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 8/6/2007 65 Female 163 lb 9/11/2007
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Iii Hospitalization 1/1/2005 Female 9/19/2007 Physician Norway
Primary
Secondary
Concomitant
Wound Treatment Hospitalization 1/25/2005 41 Female 220 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Headache 3/6/2007 Female 95 lb 12/11/2007 Physician United States
Primary
Concomitant
Throat Irritation 4/18/2007 Female 170 lb 12/14/2007 United States
Primary
Concomitant
Tendon Injury 9/1/2006 Female 100 lb 12/15/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 53 Female 250 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 11/16/2007 63 Male 1/28/2008 Consumer France
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2006 Female 117 lb 3/21/2008 Consumer United States
Primary
Concomitant
Wound Sepsis Hospitalization 2/28/2008 Male 170 lb 4/25/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 2/29/2008 Male 170 lb 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2008 Female 145 lb 6/6/2008 Consumer United States
Primary
Concomitant
Somnolence 1/1/2008 71 Female 4/10/2008 Consumer United States
Primary
Concomitant
Pulmonary Granuloma Other Serious 2/1/2008 Male 9/12/2008 Other Health Professional France
Primary
Concomitant
Skin Plaque Other Serious 10/30/2008 Female 11/21/2008 Consumer France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/13/2005 Female 146 lb 11/24/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 1/7/2008 Female 12/8/2008 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 10/30/2008 Female 12/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Incorrect Dose Administered 11/16/2008 Female 175 lb 12/12/2008 Physician United States
Primary
Concomitant
Muscular Weakness 9/20/2007 Female 162 lb 12/15/2008 Consumer United States
Primary
Concomitant
Vision Blurred 10/10/2007 Male 12/17/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 11/13/2008 67 Female 3/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Coronary Artery Disease Death 6/3/2005 Male 226 lb 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Dizziness Other Serious 12/23/2008 65 Female 3/11/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/6/2008 67 Female 3/12/2009 Consumer France
Primary
Secondary
Concomitant
Venous Occlusion Other Serious Female 3/17/2009 Physician Puerto Rico
Primary
Concomitant
Rheumatoid Arthritis 1/1/2009 175 lb 6/12/2009 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 10/15/2008 56 Female 190 lb 6/8/2009 Physician Israel
Primary
Concomitant
Generalised Oedema Hospitalization 6/23/2009 Female 316 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 72 Male 8/14/2009 Other Health Professional Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral 5/1/2009 48 Female 8/14/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 8/14/2009 68 Female 9/8/2009 Other Health Professional Germany
Primary
Secondary
Weight Decreased Other Serious 4/1/2003 38 Female 9/11/2009 United States
Primary
Concomitant
Injection Site Rash 12/1/2006 Male 173 lb 9/11/2009 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 8/1/2009 Female 9/14/2009 Consumer France
Primary
Secondary
Suicide Attempt Other Serious 2/2/2001 30 Female 273 lb 9/23/2009 United States
Primary
Concomitant
Somnolence Death 8/14/2009 68 Female 9/15/2009 France
Primary
Secondary
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 1/1/2009 Female 250 lb 10/12/2009 Physician United States
Primary
Concomitant
Sigmoiditis Other Serious 5/6/2009 58 Male 10/13/2009 Physician France
Primary
Concomitant
Venous Insufficiency Hospitalization 82 Male 10/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 82 Male 11/4/2009 Lawyer United States
Primary
Concomitant
Presyncope Hospitalization 5/4/2009 Male 214 lb 11/13/2009 United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/17/2009 United States
Primary
Concomitant
Rheumatoid Arthritis 3/21/2008 Male 170 lb 11/30/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2005 Female 178 lb 12/16/2009 Consumer United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Malaise Death Female 110 lb 1/12/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death Female 110 lb 1/19/2010 Physician United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 12/6/2008 59 Female 1/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/13/2005 Female 146 lb 1/28/2010 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased 1/1/2006 Female 240 lb 1/29/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral 12/23/2009 Male 212 lb 1/30/2010 United States
Primary
Concomitant
Pulmonary Mycosis Other Serious 6/1/2009 72 Male 2/4/2010 Other Health Professional Canada
Primary
Concomitant
Vocal Cord Thickening Other Serious 1/1/2006 Female 152 lb 2/4/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 55 Female 2/22/2010 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 5/4/2009 Male 214 lb 2/24/2010 United States
Primary
Concomitant
Pneumonia Viral Hospitalization 2/27/2010 Female 191 lb 3/8/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 10/1/2009 Female 3/15/2010 Consumer United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/1/2009 69 Male 202 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 5/4/2009 64 Male 214 lb 5/5/2010 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 5/29/2009 74 Female 5/19/2010 Physician United States
Primary
Concomitant
Erectile Dysfunction 6/1/2008 70 Male 169 lb 6/29/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 2/9/2009 57 Female 154 lb 7/23/2010 Physician United States
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 3/1/2010 67 Male 7/28/2010 Physician France
Primary
Secondary
Concomitant
Leukopenia Other Serious 1/12/2010 64 Female 140 lb 7/29/2010 Physician Chile
Primary
Secondary
Concomitant
Paraesthesia 4/26/2008 39 Female 246 lb 8/3/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 38 Female 286 lb 8/5/2010 United States
Primary
Concomitant
Pneumonia Other Serious 3/4/2010 66 Female 175 lb 8/6/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 56 Female 154 lb 8/12/2010 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 5/26/2010 57 Female 191 lb 9/1/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcus Test Positive Other Serious 10/15/2008 56 Female 190 lb 9/13/2010 Israel
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/14/2010 41 Female 411 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 11/1/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2008 56 Female 154 lb 11/3/2010 Physician United States
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 7/3/2007 64 Female 163 lb 11/15/2010 Other Health Professional France
Primary
Concomitant
Interacting
Vocal Cord Disorder 53 Female 11/19/2010 Consumer United States
Primary
Concomitant
Hiatus Hernia Other Serious 9/1/2010 50 Female 170 lb 12/16/2010 Consumer United States
Primary
Concomitant
Needle Issue 5/1/2010 12/22/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 11/1/2010 Female 1/13/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Abscess Rupture Hospitalization 3/4/2010 66 Female 175 lb 1/21/2011 Physician United States
Primary
Concomitant
Device Malfunction 6/1/2010 56 Female 215 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Rash 5/1/2010 67 Male 1/29/2011 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 7/14/2010 57 Female 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 8/1/2009 57 Female 1/30/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2009 37 Female 1/30/2011 Consumer United States
Primary
Concomitant
Postoperative Wound Infection Hospitalization 8/13/2009 51 Female 276 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Joint Swelling Hospitalization Male 309 lb 6/8/2011 Consumer South Africa
Primary
Concomitant
Hypertension Hospitalization 4/1/2011 70 Male 214 lb 6/13/2011 Consumer United States
Primary
Concomitant
Neuralgia Other Serious Female 6/29/2011 Pharmacist Ireland
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/7/2004 49 Male 7/12/2011 Lawyer United States
Primary
Concomitant
Neuralgia Other Serious Female 9/2/2011 Pharmacist Ireland
Primary
Concomitant
Malaise 1/1/2010 46 Female 122 lb 9/8/2011 Physician United States
Primary
Concomitant
Dehydration Other Serious 5/1/2008 63 Female 125 lb 9/7/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data