Hydroxychloroquine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Disorder Required Intervention 5/1/2006 Male 143 lb 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 4/5/2005 Female 139 lb 7/11/2006 France
Primary
Concomitant
Bronchopneumonia Death 3/16/2006 Female 123 lb 7/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 4/19/2006 Female 126 lb 7/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Hospitalization 4/5/2005 Female 139 lb 7/18/2006 France
Primary
Concomitant
Scotoma Other Serious 7/1/2005 Male 236 lb 3/19/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/2/2007 Female 152 lb 1/3/2008 Peru
Primary
Concomitant
Septic Shock Life Threatening 12/8/2007 Female 152 lb 1/4/2008 Peru
Primary
Concomitant
Septic Shock Life Threatening 12/8/2007 Female 152 lb 1/11/2008 Peru
Primary
Concomitant
Myocardial Infarction Death 12/26/2007 Female 254 lb 1/14/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/23/2007 Female 88 lb 1/17/2008 Consumer Brazil
Primary
Concomitant
Pancreatitis Hospitalization 4/14/2007 Male 225 lb 1/24/2008 United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 12/8/2007 Female 152 lb 1/25/2008 Peru
Primary
Concomitant
Myocardial Infarction Death 1/1/2008 Male 1/25/2008 Physician United Kingdom
Primary
Concomitant
Abortion Induced Other Serious 10/15/2007 Female 165 lb 1/25/2008 United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy 23 Female 1/25/2008 Physician Panama
Primary
Concomitant
Lung Neoplasm Other Serious 3/28/2007 Female 1/30/2008 Consumer United Kingdom
Primary
Concomitant
Synovitis Other Serious 59 Female 2/7/2008 Other Health Professional Brazil
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 2/7/2008 Consumer United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 11/1/2006 70 Female 2/8/2008 Germany
Primary
Secondary
White Blood Cell Disorder Other Serious 5/1/2005 Female 153 lb 3/26/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 10/1/2007 55 Female 155 lb 3/21/2008 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Death 3/13/2008 56 Male 3/28/2008 Consumer Brazil
Primary
Concomitant
Hypoglycaemic Unconsciousness Hospitalization 6/1/2007 62 Male 3/31/2008 Other Health Professional Turkey
Primary
Concomitant
Peripheral Embolism Life Threatening 11/7/2007 Male 251 lb 4/4/2008 United Kingdom
Primary
Secondary
Concomitant
Ovarian Epithelial Cancer Metastatic Other Serious 61 Female 4/11/2008 Finland
Primary
Concomitant
Lupus-like Syndrome Other Serious 11/7/2003 Female 4/11/2008 Physician United States
Primary
Concomitant
Vith Nerve Paralysis Other Serious 10/8/2007 Female 143 lb 4/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhage Intracranial Death 1/1/2008 Male 4/15/2008 Physician Canada
Primary
Concomitant
Tibia Fracture Other Serious 11/15/2007 Female 117 lb 4/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 2/4/2008 Female 254 lb 4/17/2008 Physician United States
Primary
Concomitant
Polymyositis Other Serious 80 Female 4/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 3/14/2008 Female 4/22/2008 Physician Denmark
Primary
Concomitant
Urticaria Other Serious 3/22/2008 Female 216 lb 4/22/2008 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 7/1/2008 74 Female 9/3/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 Male 300 lb 9/12/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2005 Female 120 lb 9/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/17/2003 45 Male 9/12/2008 Other Health Professional Italy
Primary
Concomitant
Pyrexia Other Serious 1/24/2007 60 Female 190 lb 9/12/2008 Other Health Professional Finland
Primary
Secondary
Concomitant
Accidental Needle Stick 4/1/2008 Female 159 lb 9/12/2008 Consumer United States
Primary
Concomitant
Teeth Brittle 1/1/2006 Female 195 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Irritation 7/1/2007 Female 170 lb 9/12/2008 Consumer United States
Primary
Concomitant
Viral Infection 6/1/2008 Male 150 lb 9/12/2008 Consumer United States
Primary
Concomitant
Treatment Noncompliance 1/1/2006 Female 160 lb 9/12/2008
Primary
Secondary
Concomitant
Cellulitis 6/1/2008 Female 9/12/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased 5/9/2008 Female 115 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2008 United States
Primary
Concomitant
Pyrexia 3/1/2008 Female 110 lb 9/12/2008 United States
Primary
Concomitant
Vitamin D Decreased 6/30/2008 Female 185 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Female 120 lb 9/12/2008 United States
Primary
Concomitant
Weight Increased 2/1/2008 Female 113 lb 9/12/2008 Consumer United States
Primary
Concomitant
Overdose 6/20/2008 Female 110 lb 9/12/2008 United States
Primary
Concomitant
Accidental Exposure 7/7/2008 Male 180 lb 9/12/2008 Consumer United States
Primary
Concomitant
Skin Reaction 7/2/2008 Female 160 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Pain 1/1/2008 Female 254 lb 9/12/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 7/18/2008 Female 115 lb 9/12/2008 United States
Primary
Concomitant
Skin Induration 12/1/2007 Female 110 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 7/16/2008 Female 220 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Swelling 6/22/2008 Female 220 lb 9/12/2008 Consumer United States
Primary
Concomitant
Paraesthesia 7/1/2008 Male 237 lb 9/12/2008 United States
Primary
Concomitant
Accidental Exposure 5/1/2008 53 Male 9/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Urticaria 7/17/2008 Female 106 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Irritation 8/3/2008 Female 195 lb 9/12/2008 United States
Primary
Concomitant
Sinusitis 7/27/2008 Female 180 lb 9/12/2008 United States
Primary
Concomitant
Musculoskeletal Pain 7/1/2008 Female 123 lb 9/13/2008 Physician
Primary
Concomitant
Throat Irritation 8/22/2008 Female 161 lb 9/13/2008 United States
Primary
Concomitant
Injection Site Reaction 4/1/2007 Female 148 lb 9/13/2008 Consumer United States
Primary
Concomitant
Death Other Serious Female 150 lb 9/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 60 Female 9/22/2008 United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 54 Female 9/22/2008 United States
Primary
Concomitant
Pyrexia Other Serious 8/27/2008 Female 125 lb 9/24/2008 Canada
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2008 Female 85 lb 9/26/2008 Canada
Primary
Concomitant
Endometrial Cancer Other Serious 9/15/2007 Female 137 lb 10/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 8/15/2007 Female 209 lb 10/3/2008 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 10/1/2005 62 Female 10/3/2008 Other Health Professional Italy
Primary
Concomitant
Skin Erosion Other Serious 1/1/2007 Female 165 lb 10/14/2008 Brazil
Primary
Concomitant
Renal Failure Other Serious 5/7/2008 54 Female 146 lb 10/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 9/21/2008 23 Male 10/21/2008 Physician United Kingdom
Primary
Concomitant
Device Related Infection Other Serious 1/1/2007 Female 165 lb 10/24/2008 Brazil
Primary
Concomitant
Myocardial Ischaemia Death Male 137 lb 10/24/2008 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/4/2006 64 Female 8/21/2006 Denmark
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 8/31/2006 Female 150 lb 10/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Female 150 lb 10/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Fistula Hospitalization 8/20/2008 Male 216 lb 10/29/2008 Physician Romania
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/1/2008 Male 10/30/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Carcinoma In Situ Of Skin Other Serious Female 134 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious Female 168 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Death 12/10/2007 Female 229 lb 11/6/2008 United Kingdom
Primary
Concomitant
Vasculitis Death 12/10/2007 Female 229 lb 11/10/2008 United Kingdom
Primary
Concomitant
Mental Impairment Other Serious Female 11/10/2008 Other Health Professional Canada
Primary
Concomitant
Rash Generalised Other Serious 3/3/2008 Female 128 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 2/3/2008 Female 254 lb 1/21/2009 Physician United States
Primary
Concomitant
Serum Sickness Other Serious 30 Female 1/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Sarcoidosis Other Serious 30 Female 1/30/2009 Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 128 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis 11/1/2007 Female 195 lb 3/13/2009 Physician United States
Primary
Concomitant
Toothache 11/1/2008 Female 222 lb 3/14/2009 United States
Primary
Concomitant
Pyrexia 11/25/2008 Female 3/14/2009 United States
Primary
Secondary
Concomitant
Parosmia 11/1/2008 Female 191 lb 3/14/2009 Physician United States
Primary
Concomitant
Soft Tissue Injury 10/1/2007 Female 115 lb 3/14/2009 United States
Primary
Concomitant
Sneezing 12/8/2008 Female 158 lb 3/14/2009 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 1/6/2009 Female 140 lb 3/14/2009 United States
Primary
Concomitant
Incorrect Dose Administered 1/15/2009 Female 160 lb 3/14/2009 United States
Primary
Concomitant
Emphysema Hospitalization 1/27/2009 Female 139 lb 3/18/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Septic Shock Other Serious 12/1/2008 51 Female 3/25/2009 Other Health Professional Canada
Primary
Concomitant
Malaise Hospitalization 11/1/2008 Female 175 lb 3/26/2009 Canada
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 75 Male 3/30/2009
Primary
Secondary
Concomitant
Injection Site Cellulitis Hospitalization 8/3/2002 Male 181 lb 3/31/2009 France
Primary
Concomitant
Rales Other Serious 7/9/2008 Female 132 lb 4/2/2009 United Kingdom
Primary
Concomitant
Thrombotic Stroke Hospitalization 10/1/2008 Female 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 2/9/2009 32 Female 4/3/2009 Physician Denmark
Primary
Concomitant
Vasculitis Other Serious Female 4/3/2009 Other Health Professional Israel
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/10/2009 United Kingdom
Primary
Concomitant
Incorrect Dose Administered 12/5/2006 Female 102 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 12/21/2006 Female 125 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/3/2007 Male 186 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/30/2007 Female 190 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 9/4/2007 Female 159 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 6/1/2006 Female 200 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 7/1/2007 Female 170 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 4/1/2008 Female 159 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pyrexia 3/1/2008 Female 110 lb 9/12/2009 United States
Primary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2009 United States
Primary
Concomitant
Injection Site Pain 2/1/2008 Female 150 lb 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/1/2008 Female 115 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/7/2008 Male 180 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vitamin D Decreased 6/30/2008 Female 185 lb 9/12/2009 Other Health Professional United States
Primary
Concomitant
Injection Site Haematoma 1/1/2008 Female 112 lb 9/12/2009 United States
Primary
Concomitant
Incorrect Dose Administered 9/5/2008 Male 201 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 5/1/2008 53 Male 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/3/2008 Female 195 lb 9/12/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 6/22/2008 Female 220 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/18/2008 Female 115 lb 9/12/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/1/2008 Female 254 lb 9/12/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 7/16/2008 Female 220 lb 9/12/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 16 Female 9/15/2009
Primary
Secondary
Concomitant
Pain 6/6/2009 Male 9/18/2009 United States
Primary
Concomitant
Pyrexia 6/26/2009 Female 115 lb 9/19/2009 United States
Primary
Concomitant
Pain 7/11/2009 Female 115 lb 9/19/2009 United States
Primary
Concomitant
Injection Site Pain 6/17/2009 Female 234 lb 9/19/2009 United States
Primary
Concomitant
Drug Dose Omission 7/17/2009 Female 9/19/2009 United States
Primary
Concomitant
Pain 7/10/2009 Female 9/19/2009 United States
Primary
Concomitant
Headache 8/5/2009 Female 224 lb 9/19/2009 United States
Primary
Concomitant
Drug Dose Omission 8/23/2009 Female 9/19/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2008 61 Male 143 lb 9/21/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 4/3/2008 70 Female 9/14/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 16 Female 9/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data