Methotrexate combined with Ondansetron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Infection Hospitalization 3/27/2005 Male 1/31/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/1/2005 Female 110 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Paraesthesia Required Intervention 3/18/2006 Female 90 lb 3/27/2006 Other Health Professional United States
Primary
Concomitant
Eczema Other Serious 1/1/2003 Female 39 lb 4/21/2006 Physician United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 16 Female 9/29/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Female 10/18/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 11/20/2006 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Female 11/27/2006
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 12/1/2006 Physician Australia
Primary
Secondary
Concomitant
Skin Infection Hospitalization 3/25/2005 Male 12/4/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 1/3/2007 Physician Australia
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Thrombocytopenia Required Intervention 16 Female 1/22/2007 Other Health Professional United States
Primary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 8/9/2005 Female 4/19/2007 Physician United Kingdom
Primary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/22/2007 14 Male 5/2/2007 Other Health Professional Brazil
Primary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/22/2007 14 Male 5/17/2007 Other Health Professional Brazil
Primary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/22/2007 14 Male 5/31/2007 Other Health Professional Brazil
Primary
Concomitant
Hiccups 4/25/2007 Male 147 lb 6/4/2007 Pharmacist United States
Primary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/22/2007 14 Male 6/14/2007 Other Health Professional Brazil
Primary
Concomitant
Renal Failure Other Serious 5/3/2007 20 Male 249 lb 6/5/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Life Threatening 12/16/2006 59 Female 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Sinusitis Other Serious 12/1/2006 Female 156 lb 9/7/2007 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/26/2007 14 Male 10/3/2007 Other Health Professional Brazil
Primary
Concomitant
Renal Impairment Life Threatening 9/27/2007 Male 187 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 14 Male 10/17/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Shock Hospitalization 10/21/2007 Male 84 lb 11/13/2007 United States
Primary
Secondary
Concomitant
Staring Hospitalization 11/13/2007 Female 104 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/21/2007 Male 84 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 16 Female 12/14/2007 France
Primary
Secondary
Concomitant
Polyp Other Serious 14 Male 1/11/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/24/2007 46 Female 146 lb 1/24/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 57 Male 2/11/2008 Consumer United States
Primary
Secondary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/26/2007 14 Male 2/11/2008 Other Health Professional Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/29/2007 Female 156 lb 2/22/2008 United Kingdom
Primary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Generalised Erythema Other Serious 11/14/2007 Female 132 lb 3/10/2008 Physician Germany
Primary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Movement Disorder Hospitalization 1/9/2008 13 Male 128 lb 3/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 3/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vomiting Hospitalization 3/15/2008 43 Female 128 lb 3/26/2008 Pharmacist United States
Primary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 4/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Hospitalization 7/21/2007 57 Male 4/3/2008 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 4/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Movement Disorder Hospitalization 1/9/2008 13 Male 128 lb 4/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/14/2008 13 Male 4/2/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/21/2007 Male 4/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Laryngospasm Other Serious 3/19/2008 70 Male 4/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/29/2007 Female 156 lb 4/22/2008 United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening Male 24 lb 4/25/2008 Pharmacist Spain
Primary
Concomitant
Incorrect Route Of Drug Administration 4/25/2007 45 Female 4/28/2008 Consumer United States
Primary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 168 lb 5/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 4/25/2008 United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 10/1/2004 Female 5/16/2008 Physician United States
Primary
Concomitant
Constipation Hospitalization 2/8/2008 66 Female 167 lb 5/7/2008 United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening Male 24 lb 5/29/2008 Pharmacist Spain
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Laryngospasm Other Serious 3/19/2008 Male 220 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Pyrexia Life Threatening 12/16/2006 59 Female 8/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Dysphagia 7/23/2008 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Cellulitis 6/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Pruritus Hospitalization 9/1/2007 29 Female 9/25/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Chemotherapeutic Drug Level Increased Other Serious 3/11/2008 4 Male 47 lb 10/7/2008 Pharmacist United States
Primary
Concomitant
Nephropathy Toxic Hospitalization 3/1/2008 17 Male 143 lb 10/7/2008 Pharmacist United States
Primary
Concomitant
Shock Other Serious 11/30/2007 Male 35 lb 11/3/2008 Other Health Professional Brazil
Primary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/5/2008 Female 130 lb 11/26/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Uterine Hypertonus Hospitalization 8/12/2006 Female 155 lb 12/10/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/28/2008 Female 163 lb 2/6/2009 Germany
Primary
Secondary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/18/2009 12 Male 3/13/2009 Physician Italy
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/12/2009 Female 182 lb 3/17/2009 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
Ileal Stenosis Hospitalization 3/9/2009 Female 75 lb 4/13/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/18/2009 12 Male 4/24/2009 Physician Italy
Primary
Concomitant
Blood Bilirubin Increased Required Intervention 2/22/2009 30 Female 235 lb 2/24/2009 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 5/4/2009 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization Female 196 lb 5/18/2009 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 12/15/2008 Female 196 lb 6/8/2009 Physician United Kingdom
Primary
Concomitant
Hyperthermia Hospitalization 4/16/2009 Female 96 lb 6/26/2009 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 7/27/2008 13 Male 134 lb 8/5/2009 Pharmacist Belgium
Primary
Secondary
Concomitant
Wheezing Other Serious 5/1/2009 Female 156 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/1/2009 Poland
Primary
Secondary
Concomitant
Rheumatoid Arthritis 1/1/2005 Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 7/27/2008 13 Male 134 lb 9/10/2009 Other Health Professional United States
Primary
Secondary
Hemiplegia Other Serious 8/8/2009 Male 9/17/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Tremor Other Serious 9/9/2009 65 Female 9/21/2009 Pharmacist Portugal
Primary
Concomitant
Grand Mal Convulsion Life Threatening 7/5/2008 14 Male 101 lb 9/14/2009 Physician Poland
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5 Male 9/23/2009
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/21/2009 Physician Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Vomiting 9/23/2009 Female 24 lb 9/30/2009 United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Tremor Other Serious 9/9/2009 65 Female 10/28/2009 Pharmacist Portugal
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Tremor Other Serious 9/9/2009 65 Female 11/2/2009 Pharmacist Portugal
Primary
Concomitant
Vomiting Hospitalization 12/19/2008 19 11/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 9/9/2009 Female 11/4/2009 Pharmacist Portugal
Primary
Concomitant
Hemiplegia Other Serious 8/11/2009 16 Male 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Somnambulism Other Serious 10/29/2009 10 Male 11/11/2009 Pharmacist United Kingdom
Primary
Concomitant
Constipation Hospitalization 2/8/2008 Female 167 lb 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Constipation Hospitalization 2/8/2008 Female 167 lb 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 14 Male 11/25/2009 Spain
Primary
Concomitant
Interacting
Hyperthermia Hospitalization 4/16/2009 Female 96 lb 12/2/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 14 Male 12/7/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Lymphopenia Other Serious 4/29/2009 4 Male 12/14/2009 Physician
Primary
Secondary
Renal Disorder Other Serious 14 Male 12/14/2009 Spain
Primary
Concomitant
Interacting
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Systemic Candida Hospitalization 10/4/2009 11 Female 81 lb 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Lymphopenia Other Serious 4/29/2009 4 Male 12/21/2009 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Other Serious 14 Male 1/4/2010
Primary
Secondary
Concomitant
Lymphopenia Other Serious 4/29/2009 4 Male 1/4/2010 Other Health Professional United States
Primary
Secondary
Radiation Injury Hospitalization 9 Female 1/15/2010 Physician Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 17 Male 123 lb 1/15/2010 Other Health Professional Canada
Primary
Concomitant
Screaming Hospitalization 10/4/2009 11 Female 81 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
Lung Neoplasm Hospitalization 14 Male 95 lb 1/20/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 14 Male 79 lb 1/20/2010 Physician Canada
Primary
Concomitant

Drug Data