Amitriptyline combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Basal Cell Carcinoma Other Serious 1/1/2005 Female 150 lb 1/3/2006 Physician United States
Primary
Concomitant
Pulmonary Mycosis Death 7/4/2005 Male 114 lb 1/3/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2002 61 Female 198 lb 3/20/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/31/2006 Female 130 lb 3/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Other Serious Female 157 lb 3/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 11/21/2005 Male 128 lb 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 4/23/2005 Female 207 lb 3/29/2006 Consumer United Kingdom
Primary
Concomitant
Umbilical Hernia Hospitalization 11/7/2007 56 Female 11/16/2007 Consumer Argentina
Primary
Concomitant
Hepatotoxicity Other Serious 10/10/2003 Female 121 lb 12/23/2008 Consumer United Kingdom
Primary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 12/23/2008 Other Health Professional Canada
Primary
Concomitant
Lung Adenocarcinoma Other Serious 2/27/2008 68 Female 172 lb 12/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Endometrial Cancer Other Serious 1/1/2008 50 Female 12/31/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/21/2008 Female 163 lb 2/20/2009 United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious Female 220 lb 2/20/2009 Canada
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 2/15/2008 Male 2/21/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 2/26/2009 United States
Primary
Concomitant
Hip Fracture Hospitalization 8/11/2008 Female 134 lb 2/27/2009 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Viral Hospitalization 12/2/2008 Male 168 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 6/23/2008 Female 130 lb 3/10/2009 United States
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious 11/2/2006 69 Female 3/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection 7/1/2008 Female 154 lb 3/14/2009 United States
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 2/11/2002 Female 198 lb 3/27/2009 Physician Spain
Primary
Concomitant
Fatigue 1/21/2009 41 Female 170 lb 5/15/2009 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 6/30/2009 United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 12/1/2007 Female 200 lb 7/1/2009 United States
Primary
Secondary
Concomitant
Hyperkeratosis Other Serious 10/14/2003 Female 126 lb 7/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Test Positive Other Serious 5/3/2009 52 Female 142 lb 7/7/2009 Physician Lithuania
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/1/2009 Female 134 lb 7/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/15/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Renal Failure Life Threatening 56 Male 7/16/2009 Australia
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 3/1/2009 Female 150 lb 7/17/2009 Brazil
Primary
Concomitant
Influenza Other Serious 7/2/2009 Female 148 lb 7/21/2009 Other Health Professional Chile
Primary
Secondary
Concomitant
Ear Operation Other Serious 12/1/2008 Female 238 lb 7/23/2009 Other Health Professional Canada
Primary
Concomitant
Rheumatoid Arthritis Disability 6/14/2009 60 7/24/2009 Pharmacist Canada
Primary
Concomitant
Myocardial Ischaemia Death Male 130 lb 8/11/2009 United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Death 6/15/2008 Female 8/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Umbilical Hernia Hospitalization 4/1/2009 Male 225 lb 8/19/2009 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization Male 8/21/2009 Consumer United States
Primary
Concomitant
Colitis Ulcerative Other Serious 12/1/2008 57 Female 9/1/2009 Physician Germany
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/8/2007 65 Female 8/26/2009 United Kingdom
Primary
Concomitant
Abscess Other Serious 16 Female 181 lb 9/2/2009 Physician Canada
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2009 Female 187 lb 9/2/2009 United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 10/10/2006 Male 9/11/2009 Consumer United States
Primary
Concomitant
Lymphadenopathy Other Serious 3/13/2009 55 Female 9/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 7/23/2007 67 Female 159 lb 9/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Umbilical Hernia Hospitalization 4/1/2009 Male 225 lb 9/18/2009 United Kingdom
Primary
Concomitant
Drug Dose Omission 7/4/2009 Female 98 lb 9/19/2009 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2007 Female 190 lb 9/19/2009 Physician United States
Primary
Concomitant
Vomiting 1/1/2006 Female 165 lb 9/19/2009 United States
Primary
Concomitant
Suicide Attempt Other Serious 2/2/2001 30 Female 273 lb 9/23/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2009 Female 187 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Umbilical Hernia Hospitalization 4/1/2009 Male 225 lb 9/24/2009 United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2008 77 10/1/2009 United Kingdom
Primary
Secondary
Concomitant
Prosthesis Implantation Other Serious Female 119 lb 10/8/2009 Brazil
Primary
Concomitant
B-cell Lymphoma Stage Iii Life Threatening 76 Female 10/13/2009 Physician United Kingdom
Primary
Concomitant
Nasal Disorder Hospitalization Male 201 lb 10/14/2009 United Kingdom
Primary
Concomitant
Memory Impairment Other Serious Female 10/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Death 6/1/2008 Male 205 lb 10/16/2009 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/25/2008 Female 196 lb 10/21/2009 United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/4/2009 Female 10/22/2009 Physician United Kingdom
Primary
Concomitant
Intestinal Operation Hospitalization 4/20/2009 Female 10/23/2009 Physician United Kingdom
Primary
Concomitant
Lymphoma Other Serious 9/10/2009 77 101 lb 10/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Agitated Depression Hospitalization 4/1/2009 Female 108 lb 10/30/2009 United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2009 49 Female 216 lb 11/3/2009 Other Health Professional Canada
Primary
Concomitant
Hearing Impaired Hospitalization 4/1/2004 Female 128 lb 11/4/2009 Germany
Primary
Concomitant
Skin Burning Sensation 10/28/2009 Female 190 lb 11/25/2009 Consumer United States
Primary
Concomitant
Volvulus Other Serious 11/17/2009 Male 225 lb 12/1/2009 Canada
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2006 Female 147 lb 11/30/2009 Physician United States
Primary
Concomitant
Pain Other Serious Female 128 lb 12/3/2009 Brazil
Primary
Concomitant
Intestinal Prolapse Hospitalization 4/20/2009 Female 119 lb 12/4/2009 Physician United Kingdom
Primary
Concomitant
Sinusitis Hospitalization 11/2/2009 49 Female 12/8/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Sepsis Death 6/15/2008 Female 12/9/2009 Consumer United Kingdom
Primary
Concomitant
Peripheral Ischaemia Hospitalization 1/20/2009 Female 12/11/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 10/29/2009 Female 230 lb 12/15/2009 Physician United States
Primary
Concomitant
Lymphoma Other Serious 9/10/2009 77 101 lb 12/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sensation Of Heaviness Other Serious 7/12/2009 Female 128 lb 12/17/2009 Brazil
Primary
Concomitant
Vision Blurred Other Serious 11/22/2009 Female 152 lb 12/21/2009 Brazil
Primary
Concomitant
Neutropenic Sepsis Life Threatening 3/9/2009 66 Female 115 lb 12/16/2009 Austria
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/30/2009 Female 187 lb 12/23/2009 Physician United States
Primary
Concomitant
Ovarian Cyst Other Serious Female 134 lb 12/23/2009 Brazil
Primary
Concomitant
Hypertension Other Serious 64 Female 150 lb 12/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 11/30/2009 Female 187 lb 12/31/2009 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 11/1/2009 90 Female 153 lb 1/5/2010 Pharmacist
Primary
Concomitant
Pneumonitis Hospitalization 11/30/2009 Female 187 lb 1/8/2010 Physician United States
Primary
Concomitant
Sepsis Life Threatening 5/12/2008 71 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Disorder Other Serious 2/15/2010 Female 225 lb 3/30/2010 Physician Australia
Primary
Concomitant
Renal Disorder Other Serious 2/15/2010 72 Female 225 lb 4/1/2010 Physician Australia
Primary
Secondary
Concomitant
Migraine Hospitalization 4/1/2010 35 Female 125 lb 4/22/2010 United States
Primary
Concomitant
Toxoplasmosis Disability 8/15/2009 71 Female 238 lb 4/23/2010 Physician United Kingdom
Primary
Concomitant
Myasthenia Gravis Other Serious 4/1/2010 78 Female 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/19/2010 34 Female 217 lb 4/30/2010 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/8/2010 59 Female 165 lb 5/15/2010 Physician Brazil
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/23/2010 61 Female 201 lb 5/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/1/2009 57 Female 150 lb 5/21/2010 Physician United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2010 76 Female 6/3/2010 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal 1/1/2009 62 Female 172 lb 5/11/2010 Consumer United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 11/1/2009 57 Female 154 lb 6/9/2010 Physician United States
Primary
Concomitant
Myasthenia Gravis Other Serious 12/1/2009 77 Female 6/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 2/3/2010 55 Male 203 lb 6/16/2010 Consumer United Kingdom
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 11/28/2009 59 Female 335 lb 6/18/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/15/2010 79 Female 187 lb 6/18/2010 Physician United States
Primary
Concomitant
Fistula Other Serious 11/1/2009 56 Female 150 lb 6/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/24/2010 48 Female 161 lb 6/15/2010 Consumer United States
Primary
Concomitant
Colitis Hospitalization 2/15/2010 56 Female 198 lb 6/22/2010 Physician United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Other Serious 11/1/2009 57 Female 154 lb 6/22/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2010 76 Female 6/23/2010 Consumer United States
Primary
Secondary
Concomitant
Urine Odour Abnormal 1/1/2008 53 Female 6/23/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 6/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Auricular Perichondritis Other Serious 10/5/2007 55 Male 218 lb 6/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 3/26/2007 72 Female 110 lb 6/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 4/1/2010 68 Female 180 lb 6/25/2010 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 6/25/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 7/1/2010 Physician United States
Primary
Concomitant
Peroneal Nerve Palsy Hospitalization 11/1/2009 42 Male 243 lb 7/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Upper Limb Fracture Other Serious 5/14/2007 58 Female 8/19/2010 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious 9/4/2010 62 Female 9/29/2010 Consumer Brazil
Primary
Concomitant
Major Depression Hospitalization 1/1/2008 59 Male 185 lb 10/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Polyarthritis Hospitalization 10/29/2010 54 Female 177 lb 11/29/2010 Physician Chile
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 3/1/2010 65 Male 118 lb 11/29/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 6/12/2010 13 Female 122 lb 12/3/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/4/2010 62 Female 12/7/2010 Consumer Brazil
Primary
Concomitant
Syncope Hospitalization 10/23/2008 72 Male 197 lb 11/22/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 8/12/2010 60 Female 154 lb 12/10/2010 Consumer Brazil
Primary
Concomitant
Nausea Hospitalization Female 194 lb 12/10/2010 Consumer United Kingdom
Primary
Concomitant
Injection Site Warmth 9/10/2009 12/13/2010 Physician United States
Primary
Concomitant
Blister 11/24/2009 12/14/2010 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 12/15/2010 Consumer Brazil
Primary
Concomitant
Injection Site Swelling 1/4/2010 12/15/2010 Consumer United States
Primary
Concomitant
Skin Infection 12/17/2010 Physician United States
Primary
Concomitant
Injection Site Pruritus 11/16/2009 12/19/2010 Consumer United States
Primary
Concomitant
Injection Site Haematoma 11/24/2009 12/19/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2005 56 Female 150 lb 12/20/2010 Consumer United States
Primary
Concomitant
Headache 4/19/2010 70 Female 154 lb 12/20/2010 Physician Netherlands
Primary
Concomitant
Pancreatitis Hospitalization 11/1/2010 34 Male 214 lb 12/20/2010 Consumer Brazil
Primary
Concomitant
Wrist Deformity Other Serious 1/1/2007 57 Female 159 lb 12/21/2010 Consumer Brazil
Primary
Concomitant
Red Blood Cell Abnormality 6/1/2010 38 Female 118 lb 11/6/2010 Consumer United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2001 62 Female 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/8/2010 49 Female 161 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/2001 62 Female 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2010 45 Female 117 lb 1/6/2011 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2010 45 Female 117 lb 1/7/2011 Consumer Brazil
Primary
Concomitant
Skin Ulcer Hospitalization 1/1/2010 54 Female 148 lb 1/12/2011 Consumer United States
Primary
Concomitant

Drug Data