Methotrexate combined with Vitamin D

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Cancer Other Serious 11/17/2005 Female 175 lb 1/5/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 11/1/2002 Female 1/6/2006 Physician United States
Primary
Secondary
Concomitant
Amyotrophic Lateral Sclerosis Hospitalization 3/1/2005 46 Male 1/16/2006 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/1/2005 46 Male 1/26/2006 Physician Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2003 65 Female 2/17/2006 Physician France
Primary
Secondary
Concomitant
Sudden Death Death Female 200 lb 2/24/2006 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 10/1/2002 Female 3/1/2006 Other Health Professional Norway
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2002 Female 226 lb 3/13/2006 Physician United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 2/20/2003 Female 115 lb 3/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2004 Female 3/23/2006 Physician Finland
Primary
Concomitant
Breast Cancer Other Serious 12/16/2005 Female 135 lb 3/28/2006 Physician United States
Primary
Concomitant
Hip Surgery Hospitalization 12/7/2005 51 Female 3/13/2006 Consumer Canada
Primary
Concomitant
Respiratory Failure Death 1/1/2003 Female 3/31/2006 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 5/24/2005 83 Female 3/24/2006 Canada
Primary
Concomitant
Lymphoma Life Threatening 7/15/2005 76 Female 128 lb 4/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Toothache Other Serious 10/3/2005 39 Female 128 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Adenocarcinoma Other Serious 5/5/2006 Physician United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Death 5/5/2006 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 7/23/2005 80 Female 140 lb 5/3/2006 Consumer United States
Primary
Secondary
Concomitant
Increased Tendency To Bruise Other Serious 69 Male 154 lb 5/5/2006 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2003 65 Female 5/11/2006 Physician France
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 1/1/2005 Female 204 lb 5/18/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/24/2006 Physician United Kingdom
Primary
Concomitant
Shoulder Pain Hospitalization 65 Female 5/26/2006 Other Health Professional Canada
Primary
Concomitant
Renal Failure Other Serious 4/26/2006 Female 276 lb 5/30/2006 Physician Germany
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 6/9/2006 Physician United States
Primary
Concomitant
Duodenitis Other Serious 5/3/2006 35 Female 6/21/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Burning Sensation 4/3/2006 62 Female 110 lb 6/30/2006 Consumer United States
Primary
Concomitant
Pyrexia 5/27/2006 62 Female 93 lb 6/30/2006 Consumer United States
Primary
Concomitant
Hyponatraemia Other Serious 5/3/2006 35 Female 6/30/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Somnolence Other Serious 7/7/2006 Male 7/25/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2006 Female 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 3/1/2005 Female 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 8/16/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/1/2006 Female 8/18/2006 Physician United States
Primary
Concomitant
Thyroid Disorder Other Serious 6/19/2006 65 Female 170 lb 9/5/2006 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 9/6/2006 Physician United States
Primary
Concomitant
Ovarian Cancer Other Serious 9/9/2004 Female 9/26/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 5/9/2006 Female 190 lb 9/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia 5/27/2006 62 Female 93 lb 10/2/2006 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 150 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Feeling Abnormal 5/1/2006 62 Female 8/22/2006 United States
Primary
Concomitant
Hip Fracture Other Serious 83 Female 11/1/2006 Other Health Professional Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 4/1/2006 Female 123 lb 12/7/2006 Physician United States
Primary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Breast Cancer Hospitalization 5/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Pulmonary Hypertension Hospitalization 9/1/2006 Female 12/15/2006 Physician Canada
Primary
Secondary
Concomitant
Hypertension Hospitalization 11/9/2006 55 Male 190 lb 12/15/2006 Consumer United States
Primary
Concomitant
Pharyngitis Streptococcal 5/21/2006 Female 192 lb 12/15/2006 Consumer United States
Primary
Secondary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Psoriasis Female 245 lb 12/21/2006 Other Health Professional United States
Primary
Concomitant
Paraesthesia 6/1/2006 Female 12/22/2006 Consumer United States
Primary
Concomitant
Muscle Spasms 9/1/2006 78 Female 159 lb 12/22/2006 Consumer United States
Primary
Concomitant
Headache 1/1/2006 58 Female 258 lb 12/22/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2006 Female 1/2/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/24/2002 74 Male 167 lb 10/7/2006 Physician United States
Primary
Secondary
Concomitant
Death Death 12/1/2006 81 Female 1/8/2007 Consumer Canada
Primary
Concomitant
Malaise Other Serious 10/1/2005 27 Female 1/19/2007 Physician Spain
Primary
Concomitant
Erythema Multiforme Other Serious 70 Female 1/19/2007 Physician Spain
Primary
Concomitant
Lung Infiltration Hospitalization 1/1/2006 Female 127 lb 1/25/2007 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/16/2007 84 Female 2/1/2007 Consumer Canada
Primary
Concomitant
Embolism Other Serious 1/25/2007 54 Male 164 lb 2/6/2007 Consumer United States
Primary
Concomitant
Feeling Abnormal 5/1/2006 62 Female 11/21/2006 United States
Primary
Concomitant
Menorrhagia Other Serious Female 2/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer Other Serious 7/1/2006 64 Female 121 lb 3/20/2007 Other Health Professional Canada
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 84 Female 3/27/2007 Consumer United States
Primary
Concomitant
Erythema Multiforme Other Serious 11/5/2000 70 Female 3/30/2007 Physician Spain
Primary
Concomitant
Thrombocytopenia Other Serious 1/16/2007 84 Female 3/28/2007 Consumer Canada
Primary
Concomitant
Nervous System Disorder Other Serious 1/1/2007 Female 150 lb 4/13/2007 Other Health Professional United States
Primary
Concomitant
Myelofibrosis Other Serious 1/16/2007 84 Female 4/14/2007 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 39 Female 145 lb 4/25/2007 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2007 Female 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 9/1/2005 80 Female 121 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Renal Tuberculosis Hospitalization 7/1/2006 Female 6/11/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Demyelination Other Serious 12 Female 6/13/2007 Physician Canada
Primary
Concomitant
Urinary Retention Hospitalization 1/1/2007 84 Female 6/29/2007 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2007 83 Female 7/10/2007 Consumer United States
Primary
Concomitant
Death Death Female 97 lb 7/19/2007 Other Health Professional Canada
Primary
Concomitant
Spinal Fracture Other Serious 9/1/2005 80 Female 121 lb 7/17/2007 Physician United States
Primary
Secondary
Concomitant
Seroma Hospitalization 8/15/2006 45 Female 7/30/2007 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/1/2007 40 Female 8/17/2007 Other Health Professional United States
Primary
Concomitant
Temperature Intolerance Other Serious 10/1/2006 Female 159 lb 8/20/2007 Other Health Professional Canada
Primary
Concomitant
Urinary Retention Hospitalization 1/1/2007 84 Female 8/13/2007 Physician Canada
Primary
Concomitant
Hospitalisation Hospitalization 7/23/2007 62 Female 9/4/2007 Consumer Canada
Primary
Concomitant
Myocardial Ischaemia Other Serious 8/1/2004 Female 9/4/2007 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/1/2007 84 Female 8/29/2007 Physician Canada
Primary
Concomitant
Osteonecrosis Other Serious 8/2/2006 Female 202 lb 9/7/2007 Physician United States
Primary
Concomitant
Surgery Other Serious 1/1/2007 62 Female 9/11/2007 Consumer Canada
Primary
Concomitant
Head Injury Other Serious 8/1/2007 84 Female 9/14/2007 Consumer Canada
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 84 Female 9/13/2007 Physician Canada
Primary
Concomitant
Renal Failure Death 1/1/2007 40 Female 10/2/2007 Other Health Professional United States
Primary
Concomitant
Demyelination Other Serious 12 Female 10/12/2007 Physician Canada
Primary
Concomitant
Respiratory Failure Death 7/4/2007 40 Female 10/12/2007 Other Health Professional United States
Primary
Concomitant
Demyelination Other Serious 2/14/2007 12 Female 10/12/2007 Other Health Professional Canada
Primary
Concomitant
Subdural Haematoma Other Serious 8/1/2007 84 Female 10/9/2007 Consumer Canada
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2007 71 Female 10/16/2007 Physician Canada
Primary
Concomitant
Interacting
Swelling Face Other Serious 1/1/2007 Female 191 lb 10/16/2007 United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/1/2007 71 Female 10/18/2007 Physician Canada
Primary
Concomitant
Interacting
Pneumonia Hospitalization 10/1/2007 56 Female 141 lb 11/16/2007 Physician Brazil
Primary
Secondary
Concomitant
Urosepsis Other Serious 10/1/2007 Female 11/20/2007 Other Health Professional Canada
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 74 Female 11/21/2007 Other Health Professional Canada
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 74 Female 12/3/2007 Other Health Professional Canada
Primary
Concomitant
Injection Site Reaction Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Hospitalization 10/1/2005 Female 206 lb 12/6/2007 Physician United States
Primary
Concomitant
Lymphoma Other Serious 10/31/2006 Female 132 lb 12/6/2007 Physician United States
Primary
Concomitant
Oedema Peripheral 9/13/2007 Female 119 lb 12/10/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Hepatocellular Damage 1/1/2007 Female 143 lb 12/12/2007 Physician United States
Primary
Concomitant
Injection Site Irritation 3/29/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Alopecia 8/1/2007 Female 170 lb 12/14/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection 10/5/2006 Female 150 lb 12/15/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Bladder Papilloma Other Serious 2/1/2007 Female 12/21/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 53 Female 250 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Skull Fracture Other Serious 84 Female 1/10/2008 Consumer Canada
Primary
Concomitant
Breast Cancer Other Serious 11/1/2007 Female 187 lb 1/18/2008 Other Health Professional Canada
Primary
Concomitant
Actinic Keratosis Other Serious 1/1/2006 Female 115 lb 2/5/2008 Other Health Professional Canada
Primary
Concomitant
Prostate Cancer Other Serious 10/1/2007 59 Male 276 lb 2/14/2008 Physician Germany
Primary
Concomitant
Vestibular Disorder Other Serious 1/1/2005 Female 2/15/2008 Other Health Professional Canada
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 12/10/2007 84 Female 2/29/2008 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/1/2008 86 Female 3/5/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/1/2008 86 Female 3/11/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 1/1/2008 63 Female 3/10/2008 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 10/6/2007 Female 146 lb 3/26/2008 Other Health Professional Canada
Primary
Concomitant
Heart Rate Irregular 1/9/2008 41 Female 3/27/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 1/14/2008 Male 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 12/10/2007 84 Female 3/26/2008 Consumer Canada
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious Female 144 lb 4/7/2008 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 11/6/2007 Male 160 lb 4/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Raynaud's Phenomenon 2/1/2006 54 Female 4/3/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 3/22/2006 Female 223 lb 4/25/2008 Physician United States
Primary
Concomitant
Intestinal Perforation Life Threatening 3/6/2008 Male 176 lb 4/25/2008 Consumer United Kingdom
Primary
Concomitant
Herpes Zoster Other Serious 10/6/2007 Female 146 lb 5/8/2008 Other Health Professional Canada
Primary
Concomitant
Myocardial Infarction Other Serious 4/3/2008 63 Male 5/6/2008 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Life Threatening 1/1/2008 86 Female 5/9/2008 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/14/2008 Male 161 lb 5/16/2008 Consumer Belgium
Primary
Concomitant
Intestinal Perforation Life Threatening 3/6/2008 Male 176 lb 5/20/2008 Consumer United Kingdom
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2007 Female 306 lb 5/22/2008 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 11/1/2007 Female 187 lb 5/22/2008 Other Health Professional Canada
Primary
Concomitant
Wheezing Disability 12/20/2007 45 Female 6/5/2008 Physician Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 4/15/2008 Female 199 lb 6/10/2008 Physician United States
Primary
Concomitant

Drug Data