Methotrexate combined with Tamoxifen Citrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metastases To Liver Death 2/18/2000 57 Female 3/24/2006 Other Health Professional Switzerland
Primary
Secondary
Ventricular Tachycardia Other Serious 3/1/2004 38 Female 4/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 5/6/2006 United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 9/8/1998 58 Female 6/23/2006 Other Health Professional Finland
Primary
Secondary
Rheumatoid Arthritis Other Serious 6/24/2004 60 Female 8/11/2006 Other Health Professional France
Primary
Concomitant
Surgery Other Serious 58 Female 9/19/2006 Other Health Professional Italy
Primary
Concomitant
Surgery Other Serious 68 Female 9/19/2006 Other Health Professional Italy
Primary
Concomitant
Pancreatic Carcinoma Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Death 1/1/2002 43 Female 9/28/2006 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/4/2002 56 Female 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Sepsis Neonatal Other Serious Male 3 lb 1/19/2007 Physician Austria
Primary
Concomitant
Myeloid Leukaemia Hospitalization 56 Female 6/6/2003 Physician United States
Primary
Secondary
Wound Treatment Other Serious 1/1/1997 59 Female 157 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 2/1/2006 Female 112 lb 3/29/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 51 Female 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Radiotherapy Other Serious 1/31/2001 1 Female 150 lb 9/17/2007 Lawyer United States
Primary
Secondary
Concomitant
Injection Site Reaction Hospitalization 3/1/2007 Female 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia 10/26/2007 Female 168 lb 12/14/2007 United States
Primary
Concomitant
Injection Site Bruising 9/13/2007 Female 150 lb 12/14/2007 Physician
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2000 74 Female 2/12/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 51 Female 3/21/2008 Other Health Professional United Kingdom
Primary
Interacting
Tooth Extraction Other Serious 12/12/2000 42 Female 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 4/4/2008 Other Health Professional United Kingdom
Primary
Interacting
Weight Decreased Other Serious 51 Female 4/8/2008 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 51 Female 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/11/2008 79 Female 220 lb 5/2/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 4/11/2008 79 Female 220 lb 9/4/2008 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 1/20/2009 Physician United States
Primary
Concomitant
Metastases To Liver Other Serious Female 121 lb 2/24/2009 Canada
Primary
Concomitant
Injection Site Irritation 1/1/2005 Female 190 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Incorrect Dose Administered 7/8/2007 Female 182 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/13/2007 Female 150 lb 9/12/2009 Physician
Primary
Concomitant
Weight Decreased Other Serious 51 Female 10/1/2009 Other Health Professional United Kingdom
Primary
Interacting
Osteonecrosis Other Serious 51 Female 10/1/2009 United Kingdom
Primary
Interacting
Osteonecrosis Disability 8/1/2005 Female 1/4/2010 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Disability 1/1/2004 Female 1/22/2010 Other Health Professional Italy
Primary
Concomitant
Vein Disorder Other Serious 1/1/2004 Female 258 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 8/1/2005 Female 2/1/2010 Other Health Professional Italy
Primary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/5/2010 Physician United States
Primary
Concomitant
Spinal Column Stenosis Other Serious Female 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 2/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 1/1/2004 Female 258 lb 2/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 12/26/1998 Female 150 lb 2/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 3/7/2003 Female 127 lb 2/26/2010 Physician United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 7/1/2005 Female 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/14/2005 Female 127 lb 3/12/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/9/2010 42 Female 126 lb 3/9/2010 Pharmacist United States
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/27/2004 Female 3/26/2010 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 4/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 4/9/2010 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 4/15/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 4/19/2010 Physician United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/22/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/6/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 5/7/2010 United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 12/26/1998 60 Female 150 lb 5/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 6/8/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/27/2004 46 Female 7/8/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 11/14/1998 60 Female 150 lb 8/10/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 8/16/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 9/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 6/1/1995 49 Female 245 lb 9/8/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/18/2002 51 Female 130 lb 9/15/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 9/22/2010 Other Health Professional United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 10/4/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/18/2002 51 Female 130 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 10/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/25/2010 United States
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 10/26/2010 United Kingdom
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 11/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Swelling 1/18/2010 12/21/2010 Consumer United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2001 62 Female 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/2001 62 Female 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/9/2004 69 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Back Pain Hospitalization 1/1/2003 52 Male 2/14/2011 Other Health Professional United States
Primary
Concomitant
Bronchitis Other Serious 7/9/2008 50 Female 2/16/2011 Physician United States
Primary
Concomitant
Fatigue Hospitalization 78 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Angiosarcoma Hospitalization 67 Female 2/25/2011 Physician United Kingdom
Primary
Secondary
Chondropathy Hospitalization 2/18/2002 51 Female 130 lb 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Angiosarcoma Other Serious 61 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Deep Vein Thrombosis Hospitalization 1/22/2010 64 Female 163 lb 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/9/2004 69 Female 3/23/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Hospitalization 7/9/2008 50 Female 3/22/2011 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2001 62 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 60 Female 4/11/2011 Other Health Professional Greece
Primary
Concomitant
Bronchitis Other Serious 1/1/2003 52 Male 4/15/2011 Lawyer United States
Primary
Concomitant
Failure To Thrive Other Serious 1/9/2004 69 Female 5/13/2011 Physician United States
Primary
Concomitant
Urosepsis Hospitalization 1/9/2004 69 Female 5/17/2011 Lawyer United States
Primary
Concomitant
Insomnia Death 1/1/2003 52 Male 5/19/2011 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2004 61 Female 258 lb 6/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 2/18/2002 51 Female 130 lb 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Disorder Death 7/9/2008 50 Female 6/6/2011 Lawyer United States
Primary
Concomitant
Lung Disorder Hospitalization 7/9/2008 50 Female 6/13/2011 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2003 52 Male 6/17/2011 Lawyer United States
Primary
Concomitant
Urinary Incontinence Death 7/9/2008 50 Female 6/20/2011 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/27/2008 36 Female 254 lb 6/23/2011 Consumer Netherlands
Primary
Concomitant
Fibrocystic Breast Disease Other Serious 12/12/2000 47 Female 7/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 60 Female 7/19/2011 Other Health Professional Greece
Primary
Concomitant
Phlebolith Other Serious 12/12/2000 47 Female 7/27/2011 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 2/18/2002 51 Female 130 lb 7/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arthritis Hospitalization 1/1/1997 51 Female 157 lb 8/3/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 2/18/2002 51 Female 130 lb 8/4/2011 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 1/1/2001 62 Female 8/10/2011 Lawyer United States
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 1/1/2003 57 Female 157 lb 8/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Enthesopathy Hospitalization 1/1/2003 57 Female 157 lb 8/25/2011 Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 12/12/2000 47 Female 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 1/1/2003 57 Female 157 lb 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 1/1/2004 61 Female 258 lb 9/11/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2004 73 Female 9/12/2011 Other Health Professional Italy
Primary
Concomitant
Breast Cancer Metastatic Other Serious 6/1/2002 30 Female 9/23/2011 Physician Canada
Primary
Secondary
Diabetic Enteropathy Hospitalization 1/9/2004 62 Female 10/3/2011 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization Female 10/7/2011 Physician United States
Primary
Secondary
Concomitant
Dry Eye Other Serious Female 10/11/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 74 Female 10/12/2011 Physician Cyprus
Primary
Secondary
Splenomegaly Hospitalization 6/25/2005 55 Female 10/13/2011 United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization Female 10/14/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Cirrhosis Death 51 Female 11/9/2011 Other Health Professional Israel
Primary
Secondary
Concomitant
Spinal Cord Compression Hospitalization Female 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Failure Death Female 11/17/2011 Physician Israel
Primary
Secondary
Concomitant
Cardiac Cirrhosis Other Serious 51 Female 11/20/2011 Other Health Professional Israel
Primary
Secondary
Nausea Other Serious 11/14/1998 60 Female 150 lb 11/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Failure Death 51 Female 11/18/2011 Israel
Primary
Secondary
Concomitant
Hepatic Failure Death 51 Female 12/1/2011 Other Health Professional Israel
Primary
Secondary
Dysuria Other Serious 11/14/1998 60 Female 150 lb 12/1/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data