Methotrexate combined with Nystatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 12/4/2005 21 Male 159 lb 2/17/2006 United Kingdom
Primary
Concomitant
Vein Disorder Other Serious 9/7/2005 20 Female 121 lb 2/27/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/1/2000 78 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/30/2003 77 Female 134 lb 4/11/2006 Physician United States
Primary
Concomitant
Respiratory Distress Hospitalization 1/1/2000 78 Female 150 lb 5/3/2006 Physician United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 4/17/2006 5 Female 38 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 7/30/2006 57 Male 149 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Chest Discomfort Disability 2/16/2006 43 Female 8/30/2006 Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2006 Male 29 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2006 Male 29 lb 11/6/2006 United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 50 Female 1/4/2007 Pharmacist Canada
Primary
Concomitant
Vomiting 9/9/2006 67 Male 192 lb 10/24/2006 United States
Primary
Concomitant
Heart Rate Abnormal Disability 2/16/2006 43 Female 2/17/2007 Australia
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 8/17/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 2/1/2007 Female 5/7/2007 Consumer United States
Primary
Secondary
Concomitant
Type Iii Immune Complex Mediated Reaction Other Serious 5/7/2007 1 Male 13 lb 7/19/2007 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness 10/16/2007 Female 114 lb 10/22/2007 United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 12/9/2004 Female 141 lb 1/2/2008 Physician United States
Primary
Concomitant
Tinea Pedis Other Serious Female 125 lb 2/22/2008 Consumer United States
Primary
Concomitant
Oropharyngeal Blistering Other Serious 1/7/2008 Male 161 lb 3/4/2008 Physician United Kingdom
Primary
Concomitant
Skin Injury Hospitalization 3/6/2008 49 Male 277 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 12/16/2007 38 Female 90 lb 4/2/2008 Other Health Professional Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/22/2007 Male 147 lb 4/10/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/17/2008 Physician Japan
Primary
Secondary
Concomitant
Oropharyngeal Blistering Other Serious 1/7/2008 Male 161 lb 4/18/2008 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Lymphoma Other Serious 68 Female 4/25/2008 Other Health Professional United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2008 Female 98 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 62 Male 6/23/2008 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 10/19/2004 Male 161 lb 6/30/2008 Physician Australia
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/3/2008 27 Male 88 lb 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 7/15/2008 Physician Japan
Primary
Concomitant
Palindromic Rheumatism Hospitalization 6/14/2008 38 Male 220 lb 7/11/2008 Physician Australia
Primary
Secondary
Concomitant
Injection Site Irritation 7/14/2008 Female 101 lb 9/12/2008 Consumer United States
Primary
Concomitant
Polycythaemia Hospitalization 4/9/2008 32 Female 9/15/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2008 Male 200 lb 10/6/2008 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 9/26/2008 Female 11/5/2008 Belgium
Primary
Concomitant
Coronary Artery Disease Hospitalization 9/26/2008 Female 11/12/2008 Belgium
Primary
Concomitant
Mucosal Inflammation Life Threatening 5/25/2008 Female 187 lb 6/3/2008 United States
Primary
Secondary
Concomitant
Insomnia Required Intervention 8/23/2008 42 Male 370 lb 12/2/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/6/2008 2 Male 29 lb 12/29/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 8/1/2008 Female 139 lb 2/3/2009 United Kingdom
Primary
Concomitant
Skin Cancer Other Serious 1/1/2004 75 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Hospitalization 12/16/2008 Female 3/23/2009 Physician Denmark
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/11/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 153 lb 5/12/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/30/2009 0 Female 5/21/2009 Physician United Kingdom
Primary
Concomitant
Pericarditis Hospitalization 7/1/2008 Female 190 lb 6/12/2009 United States
Primary
Concomitant
Hallucination Life Threatening 3/7/2009 30 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Malignant Palate Neoplasm Other Serious 10/4/2007 66 Male 397 lb 7/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 8/11/2009 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2008 Male 330 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Malignant Palate Neoplasm Other Serious 10/4/2007 66 Male 397 lb 8/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/22/2008 Female 8/12/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/4/2009 3 Male 30 lb 8/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/22/2008 Female 8/21/2009 Physician United Kingdom
Primary
Concomitant
Malignant Palate Neoplasm Other Serious 10/4/2007 66 Male 397 lb 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Hospitalization 2/4/2009 3 Male 30 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 67 Male 157 lb 9/1/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 9/4/2009 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 8/30/2009 Female 133 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 9/15/2009 United States
Primary
Concomitant
Sleep Disorder 7/18/2005 54 Female 236 lb 9/23/2009 United States
Primary
Concomitant
Stomatitis Other Serious 8/13/2009 Female 133 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 9/21/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 8/27/2009 72 Female 228 lb 10/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 10/30/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 10/6/2009 Male 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Malaise Hospitalization Female 110 lb 11/6/2009 Physician United States
Primary
Concomitant
Stomatitis Other Serious 8/13/2009 Female 133 lb 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 11/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 12/1/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Wound Necrosis Hospitalization Female 12/22/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 11/9/2009 3 Male 31 lb 12/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 12/3/2009 Female 200 lb 12/30/2009 Pharmacist Canada
Primary
Concomitant
Weight Decreased Hospitalization 12/14/2009 Female 18 lb 12/31/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/14/2009 Female 18 lb 1/8/2010 Physician United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Malaise Death Female 110 lb 1/12/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Death Female 110 lb 1/19/2010 Physician United States
Primary
Concomitant
Mantle Cell Lymphoma Stage Iv Death 11/10/2009 Female 1/20/2010 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 12/14/2009 Female 18 lb 1/21/2010 Physician United States
Primary
Concomitant
Sepsis Life Threatening 5/12/2008 71 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
Lung Neoplasm Hospitalization 14 Male 95 lb 1/20/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Hospitalization 6/2/2009 Male 3/15/2010 United Kingdom
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 8/27/2009 Female 228 lb 3/17/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 4/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Sinusitis Hospitalization 4/19/2010 10 Male 78 lb 4/23/2010 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant
Sciatica Other Serious 8/31/2009 53 Female 164 lb 5/10/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 2/4/2009 3 Male 32 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Vasculitis Necrotising Hospitalization 3 Female 5/13/2010 Physician Ireland
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 5/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 6/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Sarcoidosis Other Serious 1/1/2009 62 Female 183 lb 6/18/2010 Physician United States
Primary
Concomitant
Small Intestinal Perforation Hospitalization 7/4/2010 5 Male 37 lb 7/5/2010 Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 1/1/2004 75 Female 119 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 7/22/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 7/26/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Hospitalization 12/22/2008 76 Female 137 lb 8/24/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 8/25/2010 United States
Primary
Secondary
Concomitant
Pleural Infection Hospitalization 3/25/2010 60 Female 198 lb 8/25/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 9/8/2010 United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Hospitalization 12/22/2008 76 Female 137 lb 9/10/2010 Physician United Kingdom
Primary
Concomitant
Pain 8/1/2009 65 Female 150 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 9/28/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/27/2010 52 Female 110 lb 10/29/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 11/24/2010 United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 11/30/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 9/11/2009 11/30/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Temporal Arteritis Other Serious Female 12/3/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 12/13/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 44 Male 152 lb 12/20/2010 United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 10/16/2002 51 Male 154 lb 12/20/2010 Physician Japan
Primary
Concomitant
Death Death 41 Male 1/3/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Death Death 45 Male 1/4/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant

Drug Data