Baclofen combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Noncompliance Other Serious 1/1/2005 44 Female 1/4/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2004 58 Male 1/13/2006 Physician United States
Primary
Concomitant
Muscle Spasms Hospitalization 1/4/2006 Male 2/7/2006 United Kingdom
Primary
Concomitant
Tremor Other Serious 3/1/2006 59 Female 3/30/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2006 59 Female 4/20/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2006 59 Female 5/5/2006 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 50 Female 5/17/2006 United States
Primary
Concomitant
Sarcoidosis Other Serious 6/1/2001 62 Female 6/14/2006 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 1/4/2006 Male 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 12/1/2004 58 Male 8/14/2006 Physician United States
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 6/30/2006 59 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/8/2006 Other Health Professional United States
Primary
Concomitant
Synovitis Required Intervention 12/28/2005 36 Female 8/18/2006 Physician Argentina
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 6/1/2006 59 Male 8/14/2006 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 3/1/2006 59 Female 10/17/2006 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 3/1/2006 59 Female 12/29/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2006 61 Female 120 lb 1/2/2007 Other Health Professional United States
Primary
Concomitant
Synovitis Required Intervention 12/28/2004 35 Female 132 lb 12/22/2006 Physician Argentina
Primary
Concomitant
Visual Disturbance Other Serious 7/6/2006 42 Female 1/26/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Toothache Other Serious 1/1/2007 49 Female 162 lb 2/13/2007 Consumer United States
Primary
Concomitant
Wegener's Granulomatosis Other Serious 1/1/2005 39 Female 115 lb 3/22/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/23/2005 72 Female 160 lb 3/8/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 39 Female 145 lb 4/25/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 2/22/2007 38 Female 5/8/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 49 Female 162 lb 6/21/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 5/8/2000 52 Female 291 lb 9/24/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2007 75 Male 10/22/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2007 75 Male 11/6/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Death Male 152 lb 11/26/2007 United Kingdom
Primary
Concomitant
Scratch Hospitalization 10/1/2003 51 Female 205 lb 1/2/2008 Consumer United States
Primary
Concomitant
Constipation Other Serious 12/1/2007 76 Male 1/23/2008 United States
Primary
Concomitant
Constipation Other Serious 12/1/2007 76 Male 1/24/2008 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/16/2007 Female 235 lb 2/26/2008 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 10/1/2003 51 Female 205 lb 3/7/2008 Consumer United States
Primary
Concomitant
Ovarian Cyst 3/21/2008 Female 206 lb 3/24/2008 Other Health Professional United States
Primary
Concomitant
Inguinal Hernia Other Serious 12/1/2007 76 Male 150 lb 4/14/2008 United States
Primary
Concomitant
Medication Residue 3/1/2007 5/13/2008 Consumer United States
Primary
Concomitant
Pyrexia 11/1/2007 Male 142 lb 6/12/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2007 Female 125 lb 7/10/2008 United States
Primary
Secondary
Concomitant
Injection Site Pain 12/1/2006 Male 220 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Death Male 152 lb 9/19/2008 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death Male 152 lb 9/29/2008 United Kingdom
Primary
Concomitant
Cholecystectomy Other Serious 10/1/2006 48 Female 291 lb 12/11/2008 Consumer United States
Primary
Concomitant
Constipation 4/1/2008 61 Male 229 lb 1/16/2009 Consumer United States
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/1999 52 Female 3/2/2009 Physician United States
Primary
Concomitant
Cholecystectomy Other Serious 10/1/2006 48 Female 291 lb 3/5/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 112 lb 3/13/2009 Canada
Primary
Secondary
Concomitant
Wound Secretion 2/5/2009 Female 272 lb 3/14/2009 United States
Primary
Concomitant
Suicidal Ideation Hospitalization 2/19/2009 58 Male 171 lb 3/4/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 112 lb 4/3/2009 Canada
Primary
Concomitant
Interacting
Pyrexia Life Threatening 5/15/2008 66 Female 5/14/2009 United States
Primary
Concomitant
Pain 1/1/2009 Female 315 lb 6/12/2009 Consumer United States
Primary
Concomitant
Nausea 1/1/2007 Female 196 lb 6/12/2009 United States
Primary
Concomitant
Hallucination Life Threatening 3/7/2009 30 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/18/2009 Male 258 lb 7/9/2009 Other Health Professional Canada
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 1/1/2007 47 Female 9/2/2009 Other Health Professional Finland
Primary
Concomitant
Sinusitis Hospitalization 1/1/2008 45 Male 2/28/2009 Other Health Professional United States
Primary
Concomitant
Nausea 7/14/2009 Female 110 lb 9/19/2009 United States
Primary
Concomitant
Hospitalisation Hospitalization 9/28/2009 Female 190 lb 10/9/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 4/1/2008 61 Female 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 12/3/2009 Consumer United States
Primary
Concomitant
Influenza Like Illness 7/28/2009 45 Female 10/28/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 4/1/2008 61 Female 12/10/2009 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 12/1/2007 57 Female 11/25/2009 United States
Primary
Concomitant
Sinusitis 6/1/2009 Female 174 lb 1/30/2010 United States
Primary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 2/5/2010 Consumer United States
Primary
Concomitant
Swelling Other Serious 6/18/2009 Male 258 lb 2/12/2010 Other Health Professional Canada
Primary
Concomitant
Pneumonia Viral Hospitalization 2/27/2010 Female 191 lb 3/8/2010 Consumer United States
Primary
Concomitant
Lower Limb Fracture Hospitalization 12/6/2009 64 Female 3/23/2010 Consumer Canada
Primary
Concomitant
Uterine Leiomyoma Other Serious 2/1/2009 Female 172 lb 3/26/2010 Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/23/2007 62 Female 196 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
No Adverse Event 64 Female 5/3/2010 Consumer Canada
Primary
Concomitant
Tibia Fracture Other Serious 12/6/2009 64 Female 5/3/2010 Consumer Canada
Primary
Concomitant
No Adverse Event 64 Female 5/28/2010 Consumer Canada
Primary
Concomitant
Vaginal Haemorrhage Other Serious 2/1/2009 43 Female 172 lb 6/22/2010 Consumer Brazil
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/1/2009 59 Female 7/8/2010 Physician United States
Primary
Concomitant
Vision Blurred 3/1/2008 52 Female 110 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Tibia Fracture Other Serious 12/6/2009 64 Female 99 lb 8/4/2010 Physician Canada
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2009 52 Male 150 lb 8/13/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Disorder Hospitalization 1/1/2007 57 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2010 69 Female 143 lb 9/24/2010 Consumer United States
Primary
Concomitant
Tooth Disorder Hospitalization 1/1/2007 57 Female 9/30/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis 9/1/2009 50 Female 10/13/2010 United States
Primary
Concomitant
Tooth Infection Other Serious 1/1/2007 57 Female 10/14/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 11/1/2009 52 Female 10/15/2010 Consumer United States
Primary
Concomitant
Tongue Biting Other Serious 8/27/2010 68 Female 10/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/31/2004 57 Female 181 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Endometrial Cancer Stage I Other Serious 4/21/2010 12/20/2010 Physician United Kingdom
Primary
Concomitant
Paraparesis Other Serious 1/1/2010 51 Female 12/8/2010 United States
Primary
Concomitant
Myoclonus Hospitalization 10/8/2010 41 Female 12/23/2010 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mobility Decreased 1/1/2009 54 Female 209 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 7/1/2010 42 Female 1/30/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 9/2/2010 49 Female 1/30/2011 Consumer United States
Primary
Concomitant
Injection Site Swelling Hospitalization 1/14/2011 29 Female 190 lb 2/7/2011 Consumer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 1/1/2005 57 Female 181 lb 3/10/2011 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 1/1/2005 57 Female 181 lb 3/14/2011 Other Health Professional United States
Primary
Concomitant
Weight Increased 2/18/2010 42 Female 208 lb 3/25/2011 Consumer United States
Primary
Concomitant
Asthenia Other Serious 2/14/2011 68 Female 3/18/2011 Consumer United States
Primary
Concomitant
Injection Site Swelling 4/20/2010 58 Female 170 lb 5/17/2011 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/2/2005 49 Female 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 5/2/2005 49 Female 6/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 50 Female 122 lb 5/26/2011 Pharmacist United States
Primary
Concomitant
Lentigo Hospitalization 1/1/2011 55 Male 7/12/2011 Consumer United States
Primary
Secondary
Concomitant
Lentigo Other Serious 1/1/2011 55 Male 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2011 64 Male 7/21/2011 Consumer United States
Primary
Concomitant
Eye Infection Other Serious 50 Female 122 lb 7/6/2011 Physician United States
Primary
Secondary
Concomitant
Tension Headache Hospitalization 45 Female 6/1/2011 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2011 55 Male 163 lb 8/11/2011 Physician United States
Primary
Secondary
Concomitant
Infusion Site Rash 4/21/2011 39 Female 336 lb 8/18/2011 United States
Primary
Concomitant
Breast Cancer Other Serious 74 Female 8/22/2011 Consumer Canada
Primary
Concomitant
Peroneal Nerve Palsy Hospitalization 9/1/2010 25 Female 250 lb 8/31/2011 Consumer United States
Primary
Concomitant
Asthenia Other Serious Female 120 lb 10/28/2011 Consumer Canada
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 10/8/2011 9 Male 57 lb 11/3/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Myalgia 7/30/2011 52 Female 177 lb 11/7/2011 Pharmacist United States
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 10/8/2011 9 Male 55 lb 11/8/2011 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious 11/1/2010 51 Female 256 lb 12/5/2011 Consumer United States
Primary
Concomitant
Cough 8/1/2011 63 Female 157 lb 12/13/2011 Consumer United States
Primary
Concomitant
Infusion Site Warmth 4/21/2011 39 Female 336 lb 10/5/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 57 Female 1/4/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 57 Female 1/6/2012 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2010 57 Female 1/3/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 57 Female 1/10/2012 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2010 57 Female 1/9/2012 Physician United States
Primary
Secondary
Incorrect Dose Administered Death 1/1/2010 57 Female 1/10/2012 Physician United States
Primary
Secondary
Respiratory Arrest Death 57 Female 1/12/2012 Physician United States
Primary
Secondary
Renal Function Test Abnormal 1/21/2011 60 Male 1/27/2012 Consumer United States
Primary
Concomitant
Drug Ineffective 6/2/2011 66 Female 1/28/2012 Consumer United States
Primary
Concomitant
Pain In Extremity 3/30/2011 66 Female 1/28/2012 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 5/10/2011 41 Male 1/28/2012 Consumer United States
Primary
Concomitant
Cyst 64 Male 1/28/2012 Consumer United States
Primary
Concomitant
Fatigue 5/18/2011 58 Female 1/28/2012 Consumer United States
Primary
Concomitant
Nausea 6/3/2011 41 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pruritus 44 Female 1/28/2012 Consumer United States
Primary
Concomitant
Cough 3/1/2011 43 Female 150 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema 11/12/2011 46 Female 1/29/2012 Consumer United States
Primary
Concomitant
Malaise 6/15/2011 43 Female 1/28/2012 Consumer United States
Primary
Concomitant
Asthenia 6/21/2011 48 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haematoma Female 190 lb 1/29/2012 Consumer United States
Primary
Concomitant
Gout 67 Female 2/10/2012 Consumer United States
Primary
Secondary
Concomitant
Cardiomegaly Hospitalization 5/2/2005 49 Female 2/13/2012 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection 7/12/2011 50 Female 250 lb 12/20/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 57 Female 3/2/2012 Other Health Professional United States
Primary
Secondary
Hepatic Lesion Hospitalization 5/2/2005 49 Female 3/14/2012 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/2/2005 49 Female 3/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data