Furosemide combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Bacterial Other Serious 9/19/1999 69 Female 110 lb 1/4/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 77 Female 1/2/2006
Primary
Concomitant
Pancytopenia Hospitalization 69 Male 1/3/2006
Primary
Concomitant
Pancytopenia Hospitalization 82 Female 1/3/2006
Primary
Concomitant
Sepsis Hospitalization 82 Female 1/3/2006
Primary
Concomitant
Pancytopenia Hospitalization 83 Female 1/3/2006
Primary
Concomitant
Vomiting Hospitalization 5/29/2005 68 Female 110 lb 1/5/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Disorder Other Serious 10/22/2002 75 Female 185 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Trigeminal Neuralgia Hospitalization 9/2/2005 Female 1/30/2006 Denmark
Primary
Concomitant
Vomiting Hospitalization 5/29/2005 68 Female 110 lb 1/25/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/29/2005 68 Female 50 lb 2/6/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/15/2004 Male 184 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 Male 203 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Trigeminal Neuralgia Hospitalization 9/2/2005 Female 2/10/2006 Denmark
Primary
Concomitant
Rash Hospitalization 46 Female 2/6/2006 United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Pulmonary Cavitation Other Serious 6/5/2003 Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/11/2006 Female 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 57 Male 225 lb 2/22/2006 Lawyer United States
Primary
Concomitant
Tracheal Disorder Death 76 Male 2/17/2006 Germany
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Sudden Death Death Female 200 lb 2/24/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 2/27/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/15/2005 66 Male 2/14/2006 Sweden
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Death Female 3/1/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/24/2006 France
Primary
Secondary
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Hemiparesis Required Intervention 12/21/2005 63 Male 276 lb 3/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sedation Hospitalization 6/16/2003 49 Female 231 lb 3/23/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 3/29/2006 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2003 63 Female 3/23/2006 United States
Primary
Concomitant
Angioneurotic Oedema Hospitalization 11/8/2005 64 Female 4/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 76 Male 4/7/2006 Other Health Professional Germany
Primary
Concomitant
Tachycardia Other Serious 8/1/2005 Female 150 lb 4/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 8/22/2005 Female 4/14/2006 Physician United States
Primary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 4/25/2006 Consumer United States
Primary
Secondary
Concomitant
Triple Vessel Bypass Graft Hospitalization 76 Male 4/12/2006 Physician Germany
Primary
Concomitant
Scar Hospitalization 11/8/2005 64 Female 4/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/1/2004 74 Female 4/28/2006 Physician Sweden
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/1/2004 74 Female 4/28/2006 Physician Sweden
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 6/1/2003 66 Female 4/28/2006 Other Health Professional Sweden
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 2/7/2006 59 Male 5/3/2006 Pharmacist United States
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Death 5/5/2006 Physician United States
Primary
Concomitant
Lymphoma Death 1/1/2005 86 Female 5/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/16/2002 66 Female 201 lb 5/10/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2001 61 Female 168 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2005 85 Female 5/10/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 70 Female 122 lb 1/13/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Scar Hospitalization 11/8/2005 64 Female 5/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/1/2005 Female 201 lb 5/24/2006 Consumer Canada
Primary
Concomitant
Sepsis Hospitalization 82 Female 5/19/2006
Primary
Concomitant
Pancytopenia Hospitalization 82 Female 5/19/2006
Primary
Concomitant
Sepsis Hospitalization 77 Female 5/19/2006 Physician United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 83 Female 5/19/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/13/2006 81 Female 5/24/2006 Physician France
Primary
Secondary
Concomitant
Lung Disorder Death Male 6/12/2006 Physician United States
Primary
Concomitant
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Respiratory Failure Hospitalization 3/21/2006 Female 6/26/2006 Physician Canada
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Pericardial Effusion Hospitalization 10/1/2005 72 Female 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 12/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening Female 187 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 12/1/2005 Female 160 lb 7/20/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 12/14/2005 Female 201 lb 7/21/2006 Physician Canada
Primary
Concomitant
Pelvic Fluid Collection Hospitalization 3/15/2005 Female 172 lb 7/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 6/18/2006 58 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 8/3/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/14/2005 Male 168 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/15/2004 Male 184 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Death 4/29/2004 Female 201 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 9/27/2005 Female 163 lb 8/17/2006 Physician France
Primary
Concomitant
Skin Ulcer Other Serious 4/1/2005 55 Female 8/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Diverticulitis Hospitalization 12/19/2005 Male 9/6/2006 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2006 Female 331 lb 9/7/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2005 Female 180 lb 9/8/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 7/28/2006 69 Female 158 lb 9/15/2006 Consumer United States
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 9/15/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 9/9/2006 Female 138 lb 9/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/18/2006 Female 138 lb 9/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/23/2003 Female 9/26/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 5/9/2006 Female 190 lb 9/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cystitis Pseudomonal Other Serious 74 Female 152 lb 9/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 6/1/2006 Female 203 lb 10/3/2006 Consumer United States
Primary
Concomitant
Road Traffic Accident Other Serious 12/15/2005 Female 225 lb 10/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Therapy Non-responder Other Serious 76 Female 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 76 Female 10/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Neck Pain Other Serious 64 Male 201 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 63 Male 273 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Scar Other Serious 8/1/2006 Female 10/16/2006 Physician United States
Primary
Concomitant
Neck Pain Other Serious 64 Male 201 lb 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 38 Female 10/16/2006 Other Health Professional United States
Primary
Concomitant
Therapy Non-responder Other Serious Female 194 lb 11/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/13/2006 74 Male 198 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Reflux Oesophagitis Other Serious 4/24/2006 Male 163 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Non-cardiogenic Pulmonary Oedema Other Serious 5/15/2006 Female 161 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 6/30/2006 Female 11/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iii Other Serious 8/31/2006 Female 150 lb 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death 7/14/2006 Female 212 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 10/25/2006 Female 129 lb 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Glossodynia Other Serious 8/1/2005 62 Male 12/8/2006 Physician Germany
Primary
Concomitant
Glossodynia Other Serious 8/1/2005 62 Male 12/8/2006 Physician Germany
Primary
Concomitant
Tonsil Cancer Other Serious 1/1/2006 Female 182 lb 12/13/2006 Physician United States
Primary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 56 Female 1/2/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2006 61 Female 120 lb 1/2/2007 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sick Sinus Syndrome Other Serious 8/14/2006 Female 199 lb 1/10/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
Diarrhoea 7/16/2006 43 Female 135 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Gingival Bleeding 7/18/2006 40 Female 235 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Vomiting 9/9/2006 67 Male 192 lb 10/24/2006 United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Osteonecrosis Other Serious 6/29/2006 57 Female 11/28/2006 Pharmacist United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 8/1/2005 Male 220 lb 1/19/2007 Physician Germany
Primary
Concomitant
Death Death Female 128 lb 1/22/2007 France
Primary
Concomitant
Sinusitis Other Serious 8/3/2005 Female 155 lb 1/27/2007 Physician United States
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 10/1/2003 66 Male 1/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 8/26/2006 Female 218 lb 1/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 12/12/2005 63 Male 273 lb 2/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2005 64 Male 201 lb 2/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 2/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 66 Male 2/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/6/2006 Female 212 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infarction Death 11/13/2006 Female 128 lb 2/16/2007 France
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pseudoporphyria Other Serious 4/1/2005 55 Female 2/27/2007 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 7/24/2006 Female 187 lb 2/28/2007 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 7/1/2006 Male 3/1/2007 Physician United States
Primary
Concomitant
Renal Impairment Disability 2/1/2006 Female 3/7/2007 Physician Czech Republic
Primary
Concomitant
Skin Exfoliation Hospitalization 12/8/2006 83 Female 3/8/2007 Consumer France
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 8/17/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 1/1/2007 Male 3/15/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2004 72 Female 192 lb 11/27/2006 United States
Primary
Concomitant
Pancytopenia Required Intervention 9/27/2006 64 Female 3/16/2007 Pharmacist United States
Primary
Concomitant
Joint Swelling Other Serious 11/1/2006 61 Female 269 lb 3/23/2007 United Kingdom
Primary
Secondary
Concomitant

Drug Data