Kineret combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Staphylococcal Sepsis Other Serious 1/17/2006 Netherlands
Primary
Concomitant
Thrombocytopenia Other Serious 1/19/2006 Netherlands
Primary
Concomitant
Swollen Tongue Hospitalization 10/2/2005 Female 1/25/2006 Other Health Professional Sweden
Primary
Concomitant
Postoperative Wound Infection Other Serious Female 210 lb 2/7/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 1/3/2006 Male 2/16/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/22/2005 Male 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/24/2005 Female 176 lb 2/21/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Death 7/1/2004 63 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Impaired Healing Hospitalization 5/4/2005 65 Male 2/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Ovarian Cancer Metastatic Life Threatening 3/15/2004 Female 143 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/22/2005 Male 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria Pigmentosa Hospitalization 1/1/2005 Male 3/21/2006 Physician Australia
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 6/4/2005 Male 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/22/2005 Male 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 4/7/2006 Physician United States
Primary
Concomitant
Shoulder Pain Hospitalization 1/29/2006 Female 108 lb 4/14/2006 France
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 10/20/2005 Male 270 lb 4/27/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/1/2003 Male 5/17/2006 Physician Sweden
Primary
Concomitant
Urticaria Other Serious 1/1/2003 Male 5/23/2006 Physician Sweden
Primary
Concomitant
Ovarian Cancer Metastatic Life Threatening 3/15/2004 Female 143 lb 5/31/2006 Physician United Kingdom
Primary
Concomitant
Hip Arthroplasty Hospitalization 10/15/2004 Female 6/7/2006 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Life Threatening 5/15/2005 Female 6/13/2006 Other Health Professional France
Primary
Concomitant
Bowen's Disease Other Serious 3/21/2006 Female 187 lb 6/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Warmth 12/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Injection Site Pain Male 7/31/2006 Other Health Professional United States
Primary
Concomitant
Rash 1/1/2006 Female 7/31/2006 Consumer United States
Primary
Concomitant
Weight Increased Female 7/31/2006 Consumer United States
Primary
Concomitant
Urticaria 3/29/2004 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Eosinophilia 1/1/2006 Female 7/31/2006 Physician United States
Primary
Concomitant
Injection Site Reaction 7/12/2005 Female 7/31/2006 Other Health Professional United States
Primary
Concomitant
Urticaria 7/20/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Injection Site Pain 10 Female 7/31/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization Female 8/1/2006 Consumer United States
Primary
Concomitant
Glioblastoma Other Serious 4/1/2006 Female 8/4/2006 Physician Australia
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 4/29/2003 Female 8/10/2006 Physician Canada
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/10/2005 64 Female 8/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fallopian Tube Cancer Hospitalization 9/21/2005 50 Female 8/22/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cellulitis Hospitalization 8/6/2006 12 Male 103 lb 9/7/2006 Physician Canada
Primary
Concomitant
Knee Arthroplasty Hospitalization 1/1/2002 Female 9/12/2006 Consumer United States
Primary
Concomitant
Oesophageal Carcinoma Death 8/17/2006 Male 174 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 62 Female 9/19/2006 Other Health Professional
Primary
Concomitant
Pulmonary Hypertension Death 9/12/2006 18 Female 9/15/2006 Physician United States
Primary
Concomitant
Malignant Melanoma Life Threatening 60 Female 10/6/2006 Physician Greece
Primary
Concomitant
Visual Acuity Reduced Hospitalization 8/1/2005 Female 10/13/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Required Intervention 9/1/2006 18 Female 10/4/2006 Physician United States
Primary
Concomitant
Malignant Melanoma Life Threatening 6/1/2006 60 Female 128 lb 10/31/2006 Physician Greece
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 6/1/2006 60 Female 128 lb 11/7/2006 Other Health Professional Greece
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 7/10/2006 Male 174 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Multiple Sclerosis Other Serious 53 Female 11/10/2006 Physician United States
Primary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 11/6/2006 Female 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Infantile Neurological Cutaneous And Articular Syndrome Other Serious 10/25/2006 12 Male 12/8/2006 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 3/1/2006 Female 110 lb 12/11/2006 Physician United States
Primary
Concomitant
Therapy Regimen Changed Hospitalization 10/27/2005 72 Male 12/14/2006 Other Health Professional Germany
Primary
Concomitant
Malignant Melanoma Life Threatening 6/1/2006 60 Female 128 lb 12/19/2006 Physician Greece
Primary
Secondary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/3/2007 Physician United Kingdom
Primary
Concomitant
Femoral Neck Fracture Hospitalization 3/1/2004 Female 2/2/2007 Other Health Professional Germany
Primary
Concomitant
Pneumonia Legionella Other Serious 6/1/2006 53 Female 2/13/2007 Physician Spain
Primary
Concomitant
Pyrexia Hospitalization 5/31/2006 53 Male 2/14/2007 Other Health Professional Germany
Primary
Concomitant
Prosthesis Implantation Hospitalization 9/13/2005 62 Female 2/14/2007 Other Health Professional Germany
Primary
Concomitant
Prostatic Operation Hospitalization 6/15/2006 78 Male 2/14/2007 Other Health Professional Germany
Primary
Concomitant
Varicella Hospitalization 1/8/2007 6 Female 37 lb 3/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious Female 4/12/2007 Consumer Germany
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 1/27/2003 Female 5/1/2007 Other Health Professional Sweden
Primary
Concomitant
Synovitis Hospitalization 1/1/2002 Female 5/11/2007 Physician United States
Primary
Concomitant
Osteonecrosis Hospitalization 11/9/2006 Female 5/17/2007 Physician Greece
Primary
Concomitant
Pleural Effusion Other Serious 12/1/2003 Female 121 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 6/8/2007 Physician Italy
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 1/1/2007 Female 6/13/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 6/15/2007 Physician Greece
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 11/9/2006 Female 6/18/2007 Physician Greece
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 7/5/2007 Physician Italy
Primary
Concomitant
Injection Site Irritation 5/19/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Pharyngitis Streptococcal 5/19/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 8/4/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Pain In Extremity 8/4/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization Female 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Swelling 7/26/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Delayed 7/12/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Irritation 2/1/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Urticaria 7/3/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Urticaria 6/12/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 6/21/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Polymenorrhoea 10/1/2006 Female 7/11/2007 Physician United States
Primary
Concomitant
Injection Site Pain 3/19/2007 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Discolouration 1/1/2007 Male 7/11/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 3/1/2007 Female 84 lb 7/11/2007 Physician United States
Primary
Concomitant
Juvenile Arthritis 7/1/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 10/1/2006 Female 109 lb 7/11/2007 Physician United States
Primary
Concomitant
Injection Site Nodule 1/22/2007 Female 7/11/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/30/2007 Male 7/11/2007 Consumer United States
Primary
Concomitant
Pain 2/8/2007 Male 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Pain 3/10/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 11/1/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Local Swelling 11/23/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased 9/1/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 4/1/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Pain 10/30/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection 10/16/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 10/5/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 9/28/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Juvenile Arthritis 9/2/2006 Female 7/11/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 10/3/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 10/1/2006 Female 7/11/2007 Physician United States
Primary
Concomitant
Nasopharyngitis Female 7/11/2007 Consumer United States
Primary
Concomitant
Muscular Weakness 3/1/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 9/5/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 4/1/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 9/16/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 8/8/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Pain 8/23/2002 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 1/1/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Pain 2/1/2005 Female 7/11/2007 Consumer United States
Primary
Concomitant
Vaginal Infection 6/19/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 5/1/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Bruising 6/20/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Scratch Female 7/11/2007 Consumer United States
Primary
Concomitant
Pharyngitis Streptococcal 6/19/2006 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 6/2/2006 Female 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 4/1/2006 22 Female 7/11/2007 Physician United States
Primary
Concomitant
Rash 6/9/2006 Male 7/11/2007 Consumer United States
Primary
Concomitant
Parvovirus Infection Other Serious 7 Female 7/12/2007 Consumer United States
Primary
Secondary
Concomitant
Parvovirus Infection Death 7 Female 7/14/2007 Physician Greece
Primary
Secondary
Sjogren's Syndrome 1/15/2004 Female 7/16/2007 Physician Canada
Primary
Concomitant
Injection Site Erythema Other Serious 5/29/2007 48 Female 143 lb 7/23/2007 Other Health Professional Greece
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 4/29/2003 Female 7/23/2007 Physician Canada
Primary
Secondary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 7/23/2007 Physician Greece
Primary
Secondary
Respiratory Failure Hospitalization 9/19/2006 66 Male 7/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 6/1/2007 Female 137 lb 8/2/2007 Physician Canada
Primary
Concomitant
Injection Site Erythema Other Serious 5/29/2007 48 Female 143 lb 8/3/2007 Other Health Professional Greece
Primary
Concomitant
Renal Impairment Death 5/31/2007 Male 8/10/2007 Other Health Professional Italy
Primary
Concomitant
Renal Impairment Death 5/31/2007 Male 8/15/2007 Other Health Professional Italy
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/1/2006 Male 9/10/2007 Physician Austria
Primary
Concomitant
Parvovirus Infection Death 10/15/2006 7 Female 55 lb 9/20/2007 Physician Greece
Primary
Secondary
Chronic Infantile Neurological Cutaneous And Articular Syndrome Other Serious 9/15/2006 12 Male 10/5/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Death 11/15/2006 7 Female 10/13/2007 Greece
Primary
Secondary
White Blood Cell Count Decreased Death 11/15/2006 7 Female 10/13/2007 Greece
Primary
Secondary
Immunosuppression Other Serious 4/19/2007 7 Female 10/16/2007 Consumer Greece
Primary
Secondary
Concomitant
Immunosuppression Other Serious 11/15/2006 7 Female 55 lb 10/19/2007 Consumer Greece
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2007 58 Female 10/23/2007 Consumer United States
Primary
Secondary
Concomitant
Parvovirus Infection Death 10/15/2006 7 Female 55 lb 10/23/2007 Physician Greece
Primary
Secondary
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 10/23/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 11/1/2004 Female 10/29/2007 United States
Primary
Secondary
Concomitant
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 10/25/2007 Other Health Professional Greece
Primary
Secondary
Histiocytosis Haematophagic Other Serious 4/3/2007 7 Female 55 lb 10/31/2007 Consumer Greece
Primary
Secondary
Concomitant
Parvovirus Infection Death 1/1/2007 7 Female 55 lb 10/27/2007 Physician Greece
Primary
Secondary
Rheumatoid Arthritis Hospitalization 1/1/2002 Male 11/13/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2003 Male 11/27/2007 Physician United States
Primary
Concomitant

Drug Data