Colchicine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Life Threatening 6/30/2005 Female 99 lb 1/6/2006 Physician Japan
Primary
Concomitant
Heparin-induced Thrombocytopenia Death 12/5/2005 80 Male 154 lb 5/23/2006
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2005 80 Male 154 lb 6/7/2006
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/19/2006 Male 8/4/2006 Physician Turkey
Primary
Concomitant
Rash Hospitalization 5/16/2006 25 Female 9/1/2006 Other Health Professional Turkey
Primary
Concomitant
Cystitis Hospitalization 7/1/2006 72 Female 250 lb 9/1/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2006 72 Female 250 lb 9/22/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 5/16/2006 Female 97 lb 10/20/2006 Physician Turkey
Primary
Concomitant
Rash Other Serious 5/16/2006 Female 97 lb 11/13/2006 Physician Turkey
Primary
Concomitant
Nausea 12/17/2006 Female 3/27/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 5/1/2007 53 Female 210 lb 5/24/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 9/6/2007 Female 148 lb 9/12/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Death 5/1/2007 Female 110 lb 10/23/2007 Physician United States
Primary
Concomitant
Injection Site Reaction 7/1/2007 Female 12/13/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 8/29/2007 Male 185 lb 12/14/2007 United States
Primary
Concomitant
Headache Hospitalization 6/21/2007 Female 132 lb 1/28/2008 Other Health Professional Canada
Primary
Concomitant
Vomiting 8/28/2007 Male 185 lb 3/14/2008 United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/30/2007 Male 141 lb 4/3/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2/1/2008 67 Female 187 lb 4/4/2008 Physician Turkey
Primary
Concomitant
Tongue Oedema Other Serious 5/5/2008 22 Female 5/30/2008 Physician El Salvador
Primary
Concomitant
Diarrhoea Other Serious 3/2/2008 53 Male 132 lb 6/4/2008 Other Health Professional France
Primary
Concomitant
Gastrointestinal Carcinoma Death Male 8/25/2008 Physician Australia
Primary
Concomitant
Respiratory Tract Infection Death 11/2/2002 69 Male 9/23/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 7/1/2008 Female 326 lb 9/25/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Death 11/2/2002 69 Male 10/31/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 8/1/2008 53 Female 161 lb 11/21/2008 Physician Australia
Primary
Concomitant
Mass Other Serious 12/1/2007 Female 11/24/2008 Consumer Canada
Primary
Concomitant
Seborrhoeic Keratosis Other Serious 1/1/2005 Male 12/2/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 216 lb 1/12/2009
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 7/30/2007 Male 141 lb 2/2/2009 Physician Japan
Primary
Secondary
Concomitant
Psoriasis Hospitalization Male 380 lb 2/20/2009 Consumer United States
Primary
Concomitant
Septic Shock Other Serious 1/1/1998 47 Female 4/1/2009
Primary
Secondary
Vasculitis Other Serious Female 4/3/2009 Other Health Professional Israel
Primary
Concomitant
Diarrhoea Other Serious 73 Female 116 lb 4/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pericarditis Hospitalization Female 163 lb 4/28/2009 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 3/21/2009 58 5/22/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/29/2008 Female 135 lb 5/28/2009 Consumer Canada
Primary
Concomitant
Urinary Retention Other Serious 6/29/2008 Female 135 lb 7/2/2009 Physician Canada
Primary
Concomitant
Pericarditis Hospitalization 7/1/2007 53 Male 7/8/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 7/30/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 8/3/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Pericarditis Hospitalization 6/20/2007 51 Male 8/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pericarditis Hospitalization 7/1/2007 53 Male 8/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 67 Male 157 lb 9/1/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2003 38 Female 9/11/2009 United States
Primary
Concomitant
Incorrect Dose Administered 12/5/2006 Female 102 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 16 Female 9/15/2009
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 9/15/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 9/21/2009 United States
Primary
Concomitant
Venous Insufficiency Hospitalization 82 Male 10/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 11/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/4/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/17/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 66 Male 160 lb 12/1/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 12/10/2009 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 12/21/2009 Physician Costa Rica
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 7/30/2007 Male 141 lb 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection 8/11/2009 Female 1/29/2010 United States
Primary
Concomitant
Intestinal Ulcer Other Serious 6/29/2008 Male 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 7/30/2007 Male 141 lb 2/25/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 Female 126 lb 3/3/2010 Physician Costa Rica
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/21/2009 57 Female 126 lb 3/16/2010 Physician Costa Rica
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 1/1/2010 65 Male 176 lb 4/9/2010 Physician Canada
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 192 lb 4/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Myelitis Transverse Hospitalization 1/1/2010 52 Male 168 lb 5/7/2010 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 10/1/2007 63 Male 193 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 5/1/2000 48 Female 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 48 Female 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2010 46 Male 7/7/2010 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/1999 48 Female 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 38 Female 286 lb 8/5/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 6/29/2008 55 Female 135 lb 8/13/2010 Physician Canada
Primary
Concomitant
Serositis Other Serious 5/1/2010 20 Female 185 lb 8/27/2010 Physician United States
Primary
Concomitant
Serositis Other Serious 5/1/2010 20 Female 185 lb 9/2/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2009 49 Female 9/16/2010 United States
Primary
Secondary
Concomitant
Large Intestine Perforation Other Serious 10/4/2010 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2010 10/13/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/14/2010 67 Male 243 lb 10/13/2010 Physician Australia
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 1/1/2007 61 Male 270 lb 10/19/2010 Consumer United States
Primary
Concomitant
Gastric Cancer Other Serious 1/1/2010 65 Male 176 lb 10/29/2010 Physician Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/1/2010 31 Female 170 lb 11/30/2010 Consumer United States
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Other Serious 1/1/2010 48 Female 256 lb 12/17/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/1/2009 50 Female 12/29/2010 Physician Israel
Primary
Concomitant
Renal Failure Hospitalization 1/1/2007 63 Male 192 lb 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blister Hospitalization 12/18/2010 75 Female 255 lb 1/5/2011 Other Health Professional United States
Primary
Concomitant
Drug Dose Omission 1/1/2009 60 Female 170 lb 1/28/2011 Consumer United States
Primary
Concomitant
Discomfort 1/18/2010 57 Female 150 lb 1/28/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 5/1/2010 57 Female 1/29/2011 Consumer United States
Primary
Concomitant
Pain 52 Female 1/30/2011 Consumer United States
Primary
Concomitant
Decreased Appetite 6/1/2010 53 Male 195 lb 1/30/2011 Physician United States
Primary
Concomitant
Bursitis Hospitalization 7/23/2010 74 Male 1/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypocalcaemia Other Serious 12/9/2010 Male 3/8/2011 Physician United States
Primary
Concomitant
Arthralgia Other Serious 3/17/2011 58 Male 159 lb 4/18/2011 Consumer Brazil
Primary
Concomitant
Excoriation Other Serious 6/20/2010 85 Female 111 lb 5/3/2011 Physician United States
Primary
Concomitant
Polyarthritis Other Serious 5/1/2010 35 Male 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 6/20/2010 85 Female 111 lb 5/26/2011 Consumer United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 5/1/2010 35 Male 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 7 Female 6/23/2011 Other Health Professional Turkey
Primary
Secondary
Neutropenia Other Serious 3/3/2011 64 Female 6/28/2011 Other Health Professional France
Primary
Concomitant
Interacting
Blood Creatinine Increased Other Serious 3/3/2011 64 Female 6/28/2011 Other Health Professional France
Primary
Concomitant
Interacting
Mobility Decreased Other Serious 57 Male 7/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Burning Sensation Male 224 lb 8/6/2011 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious 3/23/2007 17 Male 8/15/2011 Pharmacist Spain
Primary
Concomitant
Angioedema Other Serious 65 Female 9/15/2011 Other Health Professional Turkey
Primary
Concomitant
Oesophageal Ulcer Other Serious 3/23/2007 17 Male 10/3/2011 Pharmacist Spain
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 10/19/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Wound Dehiscence Hospitalization 10/7/2011 66 Male 159 lb 10/20/2011 Physician United States
Primary
Concomitant
Drug Ineffective Death 68 Male 10/26/2011 Physician Poland
Primary
Secondary
Anaemia Other Serious 48 Female 10/27/2011 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Legionella Other Serious Female 11/3/2011 Consumer United States
Primary
Concomitant
Pyrexia 6/25/2011 58 Male 11/6/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 10/1/2011 48 Female 328 lb 10/27/2011 United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 6/20/2010 85 Female 111 lb 11/23/2011 Consumer United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Other Serious 2/1/2011 41 Male 214 lb 12/2/2011 Other Health Professional Canada
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 12/13/2011 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 1/1/2005 66 Male 12/13/2011 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 12/22/2011 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2011 24 Female 126 lb 1/4/2012 Physician France
Primary
Concomitant
Lung Neoplasm Other Serious Male 1/5/2012 Other Health Professional United States
Primary
Concomitant
Arthralgia 6/1/2010 53 Male 195 lb 1/27/2012 Physician United States
Primary
Concomitant
Injection Site Pain Female 1/27/2012 Consumer United States
Primary
Concomitant
Vision Blurred 1/27/2011 75 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pruritus 1/1/2008 57 Male 248 lb 1/28/2012 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 1/15/2012 49 Male 3/15/2012 Other Health Professional Canada
Primary
Concomitant
Vaginal Ulceration Hospitalization 62 Female 187 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Pain Other Serious 3/17/2011 58 Male 174 lb 4/17/2012 Consumer Brazil
Primary
Concomitant
Palpitations Other Serious 44 Female 259 lb 4/12/2012 Consumer United States
Primary
Concomitant
Bone Marrow Failure Hospitalization 8/1/2005 71 Female 4/25/2012 Physician
Primary
Secondary
Coagulation Time Prolonged Other Serious 4/18/2012 70 Male 280 lb 4/26/2012 Consumer United States
Primary
Concomitant
Behcet's Syndrome Other Serious 3/5/2012 55 155 lb 4/27/2012 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 70 Male 160 lb 5/3/2012 Consumer United States
Primary
Concomitant
Diverticulitis Other Serious 11/28/2011 68 Female 5/4/2012 Consumer Canada
Primary
Concomitant
Balance Disorder Other Serious 3/19/2012 58 Female 260 lb 4/25/2012 Consumer United States
Primary
Concomitant
X-ray Abnormal Death Male 215 lb 5/9/2012 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2011 59 Female 5/18/2012 Physician France
Primary
Secondary
Perineal Cyst Other Serious 8/1/2008 61 Male 264 lb 6/1/2012 Consumer United States
Primary
Secondary
Staphylococcal Sepsis Other Serious 12/1/2011 8 Female 73 lb 6/8/2012 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/1/2008 61 Male 264 lb 6/12/2012 Consumer United States
Primary
Secondary
Hypocalcaemia Other Serious 12/9/2010 89 Male 127 lb 6/14/2012 Physician United States
Primary
Concomitant
Abdominal Wound Dehiscence Hospitalization 10/7/2011 66 Male 159 lb 6/18/2012 Physician United States
Primary
Concomitant
Joint Swelling Other Serious 7/25/2011 55 155 lb 6/21/2012 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Gastric Ulcer Haemorrhage Other Serious 1/1/2011 7 Female 73 lb 6/27/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Pustular Other Serious 9/30/2011 38 Male 141 lb 6/29/2012 Physician Japan
Primary
Concomitant
Visual Impairment Hospitalization 4/1/2012 6/29/2012 Consumer United States
Primary
Concomitant

Drug Data