Methotrexate combined with Pravastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 3/1/2006 Physician United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 4/25/2006 Consumer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/14/2005 Male 168 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/5/2006 Male 229 lb 9/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/5/2006 Male 229 lb 12/7/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/14/2005 Female 88 lb 1/19/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 9/20/2006 Female 194 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 12/22/2006 Male 198 lb 2/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nosocomial Infection Hospitalization 1/1/2006 Female 2/21/2007 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/25/2007 Female 149 lb 3/21/2007 Other Health Professional Canada
Primary
Concomitant
Respiratory Failure Other Serious 2/25/2007 Female 149 lb 3/29/2007 Other Health Professional Canada
Primary
Concomitant
Metrorrhagia Other Serious 1/1/2005 60 Female 4/12/2007 Other Health Professional France
Primary
Concomitant
Metrorrhagia Other Serious 4/1/2005 60 Female 4/20/2007 Other Health Professional France
Primary
Concomitant
Mobility Decreased Other Serious 69 Female 234 lb 5/3/2007 Consumer United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 6/18/2007 Physician United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 6/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 6/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 74 Male 7/26/2007 Consumer United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious 8/1/2004 Female 9/4/2007 United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Life Threatening 5/16/2007 Female 176 lb 9/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 11/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 11/6/2007 United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 168 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Dislocation Other Serious 8/15/2007 Female 106 lb 12/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria 10/2/2007 65 Female 158 lb 12/17/2007 United States
Primary
Concomitant
Respiratory Failure Other Serious 2/25/2007 Female 149 lb 1/16/2008 Canada
Primary
Concomitant
Polymyositis Other Serious 80 Female 4/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Joint Dislocation Other Serious 8/15/2007 Female 106 lb 4/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/5/2006 Male 229 lb 4/25/2008 Physician Netherlands
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 3/7/2008 Female 159 lb 5/19/2008 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis Other Serious 3/7/2008 Female 156 lb 5/22/2008 Other Health Professional United States
Primary
Concomitant
Polymyositis Hospitalization 5/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Foreign Body Trauma Female 6/6/2008 United States
Primary
Concomitant
Ovarian Mass Other Serious Female 200 lb 6/6/2008 Canada
Primary
Concomitant
Sinusitis 2/1/2008 Female 210 lb 6/12/2008 United States
Primary
Secondary
Concomitant
Injection Site Pain 12/1/2007 Female 240 lb 6/12/2008 United States
Primary
Concomitant
Sinusitis 3/1/2004 Female 172 lb 6/12/2008 United States
Primary
Concomitant
Nasopharyngitis Other Serious 3/7/2008 Female 156 lb 6/20/2008 Other Health Professional United States
Primary
Concomitant
Polymyositis Disability 60 Female 6/9/2008 Physician France
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 3/1/2005 62 Male 6/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/25/2006 70 183 lb 8/5/2008
Primary
Concomitant
Blood Triglycerides Increased 5/1/2008 Female 215 lb 9/12/2008 Consumer United States
Primary
Concomitant
Vasculitis Disability Male 168 lb 9/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/1/2008 65 Female 10/14/2008 Physician France
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Urticaria 10/15/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 10/18/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Swelling 1/1/2008 Female 12/12/2008 United States
Primary
Concomitant
Wound Drainage Other Serious 3/16/2008 Male 280 lb 12/15/2008 Other Health Professional United States
Primary
Concomitant
Hypertonia Hospitalization Female 1/26/2009 Germany
Primary
Concomitant
Hypertonia Hospitalization Female 2/3/2009 Germany
Primary
Concomitant
Nasal Neoplasm Benign Other Serious 6/12/2006 64 Male 207 lb 2/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Nasal Neoplasm Benign Other Serious 6/12/2006 64 Male 207 lb 2/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lymphoma Hospitalization 8/1/2008 Female 86 lb 2/24/2009 Physician Japan
Primary
Concomitant
Gingival Bleeding Hospitalization 8/1/2008 Female 104 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
B-cell Lymphoma Hospitalization 8/1/2008 Female 104 lb 3/13/2009 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity 11/1/2008 Female 170 lb 3/14/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection 12/1/2008 Female 3/14/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 2/15/2009 Female 3/14/2009 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious 1/30/2009 Male 192 lb 4/24/2009 United States
Primary
Secondary
Concomitant
Suffocation Feeling Other Serious 1/1/2004 Male 227 lb 5/6/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 4/3/2009 Male 5/15/2009 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/10/2009 Male 176 lb 5/20/2009 Physician Australia
Primary
Secondary
Concomitant
Breast Cancer Other Serious 9/22/2008 41 Female 194 lb 5/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhinorrhoea 1/1/2009 Female 176 lb 6/11/2009 Physician United States
Primary
Concomitant
Eye Swelling Other Serious 3/1/2009 Female 163 lb 6/11/2009 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 8/1/2008 Male 175 lb 6/12/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Female 157 lb 6/12/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 4/25/2008 Female 137 lb 6/26/2009 Physician United States
Primary
Concomitant
Arthritis Infective Hospitalization 5/10/2009 6/30/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 4/25/2008 Female 137 lb 7/9/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 4/25/2008 Female 137 lb 7/24/2009 Physician United States
Primary
Concomitant
Sepsis Death Female 8/12/2009 United Kingdom
Primary
Concomitant
Sepsis Death Female 8/13/2009 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/1/2009 83 Female 103 lb 9/5/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 9/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 1/24/2007 Male 175 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 7/8/2007 Female 182 lb 9/11/2009 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 5/30/2009 Female 165 lb 9/18/2009 United States
Primary
Concomitant
Pain In Extremity Male 225 lb 9/19/2009 United States
Primary
Concomitant
Pain 4/1/2009 Female 219 lb 9/19/2009 United States
Primary
Concomitant
Swelling 7/1/2009 Female 138 lb 9/19/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 10/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Alveolitis Other Serious 3/1/2009 Female 164 lb 10/27/2009 Physician United States
Primary
Secondary
Concomitant
Psoriasis Hospitalization 1/1/2008 53 Male 254 lb 11/5/2009 Physician France
Primary
Concomitant
Psoriasis Hospitalization 1/1/2008 53 Male 254 lb 11/9/2009 Physician France
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sputum Purulent Hospitalization 10/1/2008 Male 11/17/2009 Consumer France
Primary
Secondary
Psoriasis Hospitalization 1/1/2008 53 Male 254 lb 11/17/2009 Physician France
Primary
Concomitant
Pelvic Abscess Hospitalization 9/1/2008 Female 229 lb 11/19/2009 Physician United States
Primary
Concomitant
Skin Ulcer 3/1/2009 Female 11/25/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2004 Female 220 lb 11/30/2009 Consumer United States
Primary
Secondary
Concomitant
No Adverse Event Female 145 lb 12/1/2009 Physician United States
Primary
Concomitant
Ulcer 3/16/2009 Female 118 lb 12/8/2009 Physician United States
Primary
Concomitant
Injection Site Pain 10/13/2009 Female 198 lb 1/30/2010 United States
Primary
Concomitant
Cardiomyopathy Hospitalization 1/26/2010 Female 167 lb 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/22/2010 Male 187 lb 2/10/2010 Physician Mexico
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/22/2010 Male 187 lb 2/16/2010 Physician Mexico
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/22/2010 Male 187 lb 2/24/2010 Physician Mexico
Primary
Secondary
Concomitant
Mycobacterium Chelonei Infection Other Serious 53 Female 262 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Stress Cardiomyopathy Hospitalization 1/25/2010 Female 115 lb 3/2/2010 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/22/2010 Male 187 lb 3/4/2010 Physician Mexico
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/22/2010 Male 187 lb 3/10/2010 Physician Mexico
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 6/15/2009 Male 117 lb 3/16/2010 Physician Japan
Primary
Concomitant
Leukopenia Hospitalization 3/3/2010 68 Female 117 lb 3/18/2010 Physician Germany
Primary
Concomitant
Leukopenia Hospitalization 3/3/2010 68 Female 117 lb 3/24/2010 Other Health Professional Germany
Primary
Concomitant
Cardiomyopathy Hospitalization 1/25/2010 Female 115 lb 3/24/2010 Physician Brazil
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 1/25/2010 Female 115 lb 3/29/2010 Physician Brazil
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 6/15/2009 79 Male 117 lb 4/2/2010 Physician Japan
Primary
Concomitant
Tic Other Serious 2/1/2010 Female 3/30/2010 Consumer United States
Primary
Concomitant
Ocular Hyperaemia 66 Female 4/6/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 3/13/2010 60 Male 209 lb 4/5/2010 Australia
Primary
Concomitant
Swollen Tongue Other Serious 3/26/2010 67 Male 240 lb 4/13/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/23/2007 62 Female 196 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 4/20/2010 United States
Primary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/13/2010 60 Male 209 lb 4/29/2010 Australia
Primary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 3/5/2010 63 Female 117 lb 5/27/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2010 76 Female 6/3/2010 Consumer United States
Primary
Concomitant
Cardiomyopathy Hospitalization 1/25/2010 67 Female 115 lb 6/11/2010 Physician Brazil
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2010 76 Female 6/23/2010 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 3/15/2010 63 Female 117 lb 6/28/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/16/2010 74 Male 6/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 67 Female 6/30/2010 United States
Primary
Concomitant
Skin Lesion Other Serious 3/1/2010 42 Female 7/1/2010 Consumer United States
Primary
Concomitant
Myalgia Other Serious 6/20/2010 72 Female 6/30/2010 Consumer United States
Primary
Concomitant
Psoriasis Other Serious 3/1/2010 42 Female 7/9/2010 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 2/23/2010 44 Female 217 lb 7/13/2010 Physician United States
Primary
Concomitant
Lobar Pneumonia Hospitalization 4/5/2010 62 Female 7/8/2010 United States
Primary
Concomitant
Procedural Pain Hospitalization 4/1/2010 73 Male 260 lb 7/16/2010 Consumer United States
Primary
Concomitant
Vomiting 11/5/2007 59 Female 115 lb 7/17/2010 Consumer United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 3/1/2010 72 Male 7/30/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 3/1/2010 72 Male 8/5/2010 Physician Netherlands
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 67 Female 8/18/2010 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 12/1/2009 72 Female 8/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
Heart Valve Incompetence Other Serious 7/31/2010 64 Female 8/19/2010 Consumer United States
Primary
Concomitant
Optic Neuritis Other Serious 8/3/2010 67 Female 180 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Heart Valve Incompetence Other Serious 7/31/2010 64 Female 8/24/2010 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 65 Female 8/26/2010 Consumer United States
Primary
Concomitant
Optic Neuritis Disability 8/3/2010 67 Female 180 lb 9/4/2010 Other Health Professional United States
Primary
Concomitant
Myalgia Male 9/7/2010 Consumer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Disability 63 Male 265 lb 9/8/2010 Other Health Professional Switzerland
Primary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain 8/1/2009 65 Female 150 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 2/16/2010 44 Female 217 lb 9/16/2010 Physician United States
Primary
Concomitant
Thyroid Disorder Other Serious 5/1/2009 66 Female 120 lb 9/29/2010 Consumer United States
Primary
Concomitant

Drug Data