Methotrexate combined with Mucosta

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 6/18/2004 Female 1/5/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/18/2004 Female 104 lb 1/12/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/29/2005 Male 161 lb 2/10/2006 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/21/2005 Male 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/21/2005 Male 3/10/2006 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 4/1/2005 76 Male 3/18/2006 Pharmacist Japan
Primary
Concomitant
Anaphylactoid Reaction Other Serious 8/26/2005 Female 88 lb 4/11/2006 Physician Japan
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 5/17/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 3/14/2005 Male 121 lb 5/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 12/17/2003 Female 117 lb 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Disability 7/18/2006 Female 137 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 6/1/2006 Female 134 lb 8/17/2006 Physician Japan
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 9/6/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Hospitalization 2/14/2005 Female 99 lb 9/11/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 10/11/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/5/2004 47 Female 11/6/2006 Physician Japan
Primary
Concomitant
Rash Hospitalization 12/23/2003 54 Male 176 lb 12/11/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/5/2004 47 Female 12/22/2006 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 6/20/2006 Female 104 lb 1/3/2007 Physician Japan
Primary
Secondary
Concomitant
Haematochezia Hospitalization 6/19/2006 Female 104 lb 1/22/2007 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 6/20/2006 Female 104 lb 2/6/2007 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 6/1/2006 Female 134 lb 2/20/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/24/2005 Female 99 lb 3/12/2007 Japan
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 3/12/2007 Female 97 lb 4/10/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/3/2006 Female 106 lb 5/16/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/30/2005 63 Female 139 lb 6/15/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/2005 Female 99 lb 6/19/2007 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/2005 Female 99 lb 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 6/1/2006 Female 134 lb 7/19/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 12/20/2006 Female 84 lb 8/31/2007 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 12/5/2006 70 Female 9/3/2007 Pharmacist Japan
Primary
Secondary
Sputum Culture Positive Life Threatening 8/14/2007 Male 126 lb 9/11/2007 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Life Threatening 7/1/2007 Male 139 lb 9/14/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/14/2005 Male 104 lb 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Life Threatening 7/1/2007 Male 139 lb 9/21/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/20/2006 Female 84 lb 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Haematochezia Hospitalization 6/19/2006 Female 110 lb 10/17/2007 Physician Japan
Primary
Concomitant
Small Cell Lung Cancer Extensive Stage Life Threatening 7/1/2007 Male 139 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/12/2007 Physician Japan
Primary
Concomitant
Haematochezia Hospitalization 6/19/2006 Female 110 lb 11/15/2007 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 8/14/2007 Male 126 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 11/29/2007 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 3/28/2007 29 Male 163 lb 12/14/2007 Physician Japan
Primary
Concomitant
Small Cell Lung Cancer Extensive Stage Life Threatening 8/7/2007 Male 139 lb 1/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 7/1/2006 Female 110 lb 1/31/2008 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 9/25/2007 Male 88 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Infusion Related Reaction 3/12/2007 Female 97 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/30/2005 Female 139 lb 2/12/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 9/24/2005 Male 143 lb 2/27/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Small Cell Lung Cancer Extensive Stage Life Threatening 8/7/2007 Male 139 lb 3/7/2008 Physician Japan
Primary
Secondary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 4/14/2005 Female 99 lb 3/7/2008 Physician Japan
Primary
Concomitant
Breast Cancer Life Threatening 10/1/2005 Female 154 lb 3/24/2008 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 9/30/2005 Female 139 lb 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Quadriplegia Hospitalization 12/7/2007 Female 126 lb 4/2/2008 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 11/15/2007 Female 110 lb 4/2/2008 Physician Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 8/1/2006 Female 110 lb 5/30/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 163 lb 6/20/2008 Physician Japan
Primary
Concomitant
Hodgkin's Disease Hospitalization 8/12/2004 Male 123 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Life Threatening 10/1/2005 Female 154 lb 7/8/2008 Physician Japan
Primary
Concomitant
Pustular Psoriasis Other Serious 8/1/2006 Female 110 lb 7/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Mycoplasmal Hospitalization 5/15/2008 Female 93 lb 7/21/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/15/2008 Male 8/26/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 5/1/2008 Female 8/27/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/1/2008 Female 9/15/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Female 10/30/2008 Other Health Professional Japan
Primary
Concomitant
Pleural Effusion Life Threatening 8/7/2008 Female 77 lb 10/31/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/4/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/7/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2008 58 Female 11/14/2008 Other Health Professional Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 11/21/2008 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization 7/23/2008 Female 154 lb 11/25/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/30/2008 Female 101 lb 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 2/13/2009 Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/7/2008 Female 77 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 3/20/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/7/2006 Male 167 lb 4/24/2009 Japan
Primary
Concomitant
Tuberculosis Of Genitourinary System Life Threatening 3/3/2009 Female 5/5/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 2/24/2009 Female 117 lb 5/8/2009 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 8/26/2008 Female 119 lb 5/22/2009 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 7/24/2008 Female 86 lb 5/27/2009 Physician Japan
Primary
Concomitant
Tuberculosis Of Genitourinary System Other Serious 3/3/2009 Female 5/28/2009 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 8/26/2008 Female 119 lb 6/4/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 2/24/2009 Female 117 lb 7/27/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/24/2009 Female 8/6/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/3/2009 Female 126 lb 8/13/2009 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 7/20/2009 Female 9/4/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/24/2009 Female 9/4/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/3/2009 Female 126 lb 9/4/2009 Japan
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 5/20/2009 Male 148 lb 9/16/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/24/2009 Female 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 Female 103 lb 10/30/2009 Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/24/2008 Female 86 lb 11/20/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/3/2009 Female 126 lb 11/24/2009 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 2/15/2009 Female 117 lb 12/14/2009 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 11/10/2009 Male 148 lb 12/22/2009 Physician Japan
Primary
Concomitant
Hepatitis B Other Serious 6/8/2009 Female 103 lb 12/23/2009 Japan
Primary
Concomitant
Herpes Zoster Hospitalization 5/6/2008 Male 110 lb 12/30/2009 Japan
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/15/2008 Male 108 lb 1/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 5/6/2008 Male 110 lb 1/8/2010 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 2/15/2009 Female 117 lb 1/21/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 1/1/2010 Female 104 lb 1/22/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 5/6/2008 Male 110 lb 1/25/2010 Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 Female 103 lb 1/29/2010 Japan
Primary
Concomitant
Herpes Zoster Hospitalization 5/6/2008 Male 110 lb 2/1/2010 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/24/2009 Female 2/4/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 1/20/2010 Female 99 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 2/15/2009 Female 117 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 11/10/2009 Male 148 lb 2/16/2010 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 1/20/2010 Female 99 lb 2/17/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/31/2009 Female 104 lb 2/23/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 Female 103 lb 2/25/2010 Japan
Primary
Concomitant
Spinal Compression Fracture Life Threatening 6/1/2009 Female 73 lb 3/1/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 1/1/2009 Female 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 Female 103 lb 3/5/2010 Japan
Primary
Concomitant
Osteomyelitis Hospitalization 9/8/2009 Female 99 lb 3/14/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/24/2008 Female 86 lb 3/15/2010 Physician Japan
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 6/15/2009 Male 117 lb 3/16/2010 Physician Japan
Primary
Concomitant
Uterine Leiomyoma Other Serious 8/7/2009 Female 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 9/8/2009 Female 99 lb 3/25/2010 Physician Japan
Primary
Concomitant
Lymph Node Tuberculosis Other Serious 6/15/2009 79 Male 117 lb 4/2/2010 Physician Japan
Primary
Concomitant
Hepatitis B Other Serious 6/8/2009 17 Female 103 lb 4/5/2010 Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 2/12/2010 79 Female 4/16/2010 Japan
Primary
Concomitant
Pyrexia Other Serious 3/30/2010 Female 256 lb 5/3/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 3/31/2009 83 Female 110 lb 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 17 Female 103 lb 5/7/2010 Japan
Primary
Concomitant
Pleurisy Hospitalization 2/12/2010 79 Female 5/20/2010 Japan
Primary
Concomitant
Hepatitis B Other Serious 6/8/2009 17 Female 103 lb 5/28/2010 Japan
Primary
Concomitant
Pyrexia Other Serious 3/30/2010 39 Female 116 lb 6/8/2010 Physician United States
Primary
Secondary
Concomitant
Vestibular Disorder Congenital Anomaly 11/1/2009 84 Male 6/11/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 4/2/2010 48 Female 88 lb 6/18/2010 Physician Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Hospitalization 3/8/2007 59 Female 7/12/2010 Physician Japan
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Hospitalization 3/8/2007 59 Female 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 17 Female 103 lb 7/23/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased 1/25/2010 68 Female 75 lb 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 8/2/2010 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 11/24/2006 51 Male 115 lb 8/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 6/8/2009 17 Female 103 lb 8/17/2010 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 11/24/2006 51 Male 115 lb 8/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/18/2008 31 Female 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Angiosarcoma Death 8/16/2010 77 Female 104 lb 9/7/2010 Physician Japan
Primary
Concomitant
Angiosarcoma Death 8/16/2010 77 Female 104 lb 9/13/2010 Physician Japan
Primary
Concomitant
Brain Abscess Death 2/26/2010 76 Female 104 lb 9/15/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 9/23/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 1/1/2009 58 Female 123 lb 9/24/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data