Methotrexate combined with Thymoglobulin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 2/1/2006 Male 168 lb 3/28/2006 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 7/27/2006 51 Male 181 lb 8/16/2006 Physician United States
Primary
Concomitant
Sputum Culture Positive Life Threatening 10/19/2006 35 Female 294 lb 11/9/2006 Other Health Professional United States
Primary
Concomitant
Sputum Culture Positive Life Threatening 10/19/2006 35 Female 294 lb 12/6/2006 Other Health Professional United States
Primary
Concomitant
Tachypnoea Life Threatening 10/25/2006 63 Male 12/13/2006 Other Health Professional United States
Primary
Concomitant
Restlessness Life Threatening 10/25/2006 63 Male 12/19/2006 Physician United States
Primary
Concomitant
Restlessness Life Threatening 10/25/2006 63 Male 1/18/2007 Physician United States
Primary
Concomitant
Pleural Effusion Life Threatening 1/1/2007 38 Female 117 lb 5/14/2007 Physician France
Primary
Concomitant
Encephalitis Other Serious 13 Male 7/24/2007 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 1/1/2007 38 Female 117 lb 8/10/2007 Physician France
Primary
Concomitant
Lymphoproliferative Disorder Death 5/6/2004 38 Female 128 lb 2/28/2005 Other Health Professional Poland
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 5/2/2006 62 Male 218 lb 1/15/2007 Other Health Professional United States
Primary
Concomitant
Cystitis Hospitalization 8/27/2006 44 Female 173 lb 1/15/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Life Threatening 1/1/2007 38 Female 117 lb 10/11/2007 Physician France
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Herpes Zoster Other Serious 11 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Neutropenia Other Serious 4 Female 4/14/2008 Other Health Professional Germany
Primary
Secondary
Neutropenia Other Serious 11 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Venoocclusive Liver Disease Other Serious 11/1/2007 12 Male 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/29/2008 Iceland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/2/2008 Iceland
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 21 Male 6/24/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 7/23/2008 Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 39 Male 7/25/2008 Other Health Professional Germany
Primary
Secondary
Vomiting Hospitalization 39 Male 7/28/2008 Other Health Professional Germany
Primary
Secondary
Guillain-barre Syndrome Other Serious 23 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Other Serious 8/12/2008 Canada
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 23 Male 8/13/2008 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Other Serious 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/31/2008 54 Male 164 lb 8/26/2008 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/8/2008 Physician United States
Primary
Secondary
Concomitant
Fungal Rhinitis Other Serious 41 Male 7/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/31/2008 54 Male 164 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Miller Fisher Syndrome Other Serious 9 Female 10/24/2008 Physician Italy
Primary
Secondary
Vomiting Life Threatening 3/6/2007 57 Female 11/10/2008 Japan
Primary
Concomitant
Toxic Encephalopathy Other Serious 9 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Insomnia Required Intervention 8/23/2008 42 Male 370 lb 12/2/2008 Physician United Kingdom
Primary
Concomitant
Rash Other Serious 12/27/2007 Female 44 lb 12/5/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 62 Female 163 lb 1/23/2009 Consumer France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 62 Female 163 lb 1/27/2009 Consumer France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 11/25/2008 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2008 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/25/2008 62 Female 163 lb 1/28/2009 Other Health Professional France
Primary
Concomitant
Liver Disorder Life Threatening 3/20/2009 16 Female 106 lb 4/3/2009 Physician Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 16 Female 4/3/2009 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 3/20/2009 16 Male 106 lb 4/22/2009 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 1 5/28/2009 United Kingdom
Primary
Secondary
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 27 Male 8/11/2009 Consumer Taiwan, Province Of China
Primary
Concomitant
Septic Shock Other Serious 29 Female 8/11/2009 Consumer Taiwan, Province Of China
Primary
Concomitant
Septic Shock Other Serious 27 Female 8/11/2009 Consumer Taiwan, Province Of China
Primary
Concomitant
Haematuria Other Serious 10 Male 8/12/2009 Consumer Taiwan, Province Of China
Primary
Secondary
Concomitant
Sepsis Other Serious 36 Male 8/13/2009 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 9/1/2004 31 Male 8/26/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 9/1/2004 31 Male 10/14/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Splenomegaly Other Serious 12 Male 10/29/2009 Physician Italy
Primary
Concomitant
Transplant Rejection Other Serious 8 Male 11/24/2009 Other Health Professional Italy
Primary
Concomitant
Transplant Rejection Other Serious 13 Male 11/24/2009 Other Health Professional Italy
Primary
Concomitant
Transplant Rejection Other Serious 5 Male 11/24/2009 Other Health Professional Italy
Primary
Concomitant
Renal Failure Other Serious 9/19/2009 58 Male 181 lb 12/7/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/19/2009 58 Male 181 lb 12/7/2009 Physician France
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9/29/2009 58 Male 12/16/2009 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Death 9/16/2009 24 Female 126 lb 12/31/2009 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 5/29/2009 Female 2/6/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Zygomycosis Other Serious 1/1/2006 Male 2/12/2010 Physician Italy
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Other Serious 16 Male 3/23/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Other Serious 7/6/2009 16 Male 110 lb 4/5/2010 Physician Japan
Primary
Concomitant
Tonsillectomy Other Serious 10 Male 4/5/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Arrest Death 11/30/2009 27 Female 220 lb 4/9/2010 Physician Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 5/1/2007 65 Male 99 lb 5/26/2010 Consumer Japan
Primary
Concomitant
Visual Impairment Disability 3/11/2009 48 Female 84 lb 4/29/2010 Physician Japan
Primary
Concomitant
Splenomegaly Required Intervention 4/24/2006 10 Male 33 lb 4/20/2010 Physician Italy
Primary
Concomitant
Pancytopenia Other Serious 12/27/2008 52 Male 152 lb 5/27/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/13/2009 16 Male 108 lb 5/26/2010 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 6/16/2010 Spain
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 6/16/2010 Spain
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 4/14/2010 60 Male 110 lb 6/25/2010 Physician Japan
Primary
Concomitant
Trichosporon Infection Death 12/10/2008 54 Male 132 lb 6/18/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/12/2010 59 Male 132 lb 7/16/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/12/2010 59 Male 132 lb 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 7/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Death Death 7/20/2010 Other Health Professional Canada
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 7/20/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 7/21/2010 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 7/23/2010 Other Health Professional United States
Primary
Concomitant
Graft Versus Host Disease Death 7/23/2010 Other Health Professional United States
Primary
Concomitant
Neurotoxicity Death 7/23/2010 Other Health Professional United States
Primary
Concomitant
Neurotoxicity Death 7/23/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 3/11/2009 48 Female 84 lb 7/19/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/20/2009 50 Female 97 lb 8/3/2010 Physician Japan
Primary
Concomitant
Transplant Failure Other Serious 12/1/2009 60 Male 126 lb 8/4/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/21/2009 37 Female 93 lb 8/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 8/11/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 22 Male 8/27/2010 Other Health Professional France
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 12/10/2009 5 Male 53 lb 9/1/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8/30/2010 Physician Italy
Primary
Concomitant
Unevaluable Event Other Serious Male 8/30/2010 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/13/2009 4 Female 31 lb 9/9/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 21 Female 9/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 8 Male 9/24/2010 Other Health Professional United States
Primary
Concomitant
Guillain-barre Syndrome Other Serious 51 Female 9/29/2010 Other Health Professional Italy
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 58 Female 9/30/2010 Physician Japan
Primary
Concomitant
Stenotrophomonas Sepsis Other Serious 58 Female 10/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 9 Female 9/30/2010 Physician Italy
Primary
Concomitant
Therapeutic Response Decreased Other Serious 58 Female 10/6/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Stenotrophomonas Sepsis Other Serious 8/11/2009 58 Female 10/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 21 Female 10/13/2010 Other Health Professional Germany
Primary
Concomitant
Pneumonia Cytomegaloviral Death Male 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/22/2010 14 Female 97 lb 10/22/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 1/14/2009 67 Male 99 lb 10/26/2010 Consumer Japan
Primary
Concomitant
Transplant Failure Other Serious 12/27/2008 52 Male 152 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Life Threatening 1/29/2010 59 Male 176 lb 11/3/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 21 Female 11/5/2010 Other Health Professional Germany
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 20 Male 11/5/2010 Other Health Professional France
Primary
Concomitant
Sepsis Other Serious 5/26/2009 7 Female 29 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 12/27/2008 52 Male 152 lb 10/26/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 21 Female 11/4/2010 Other Health Professional Germany
Primary
Concomitant
Sepsis Death 11/12/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Myocardial Infarction Death 14 Female 11/17/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Thrombotic Microangiopathy Death 11/17/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Thrombotic Microangiopathy Death 11/17/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 3 Male 11/10/2010 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 11/22/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Fungal Sepsis Death 11/22/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 11/22/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Lung Disorder Death 11/22/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant

Drug Data