Bleomycin Sulfate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Deafness Hospitalization 12/2/2005 57 Female 1/18/2006 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 11/12/2004 61 Male 181 lb 1/18/2006 Consumer United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 11/12/2004 69 Male 181 lb 1/17/2006 Physician France
Primary
Secondary
Concomitant
Deafness Unilateral Hospitalization 12/2/2005 57 Female 1/24/2006 Physician France
Primary
Secondary
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 3/28/2006 Physician France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/4/2006 40 Female 209 lb 3/28/2006 Consumer France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/4/2006 40 Female 209 lb 4/13/2006 Physician France
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 2/24/2006 31 Male 5/8/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 40 Female 5/19/2006 Consumer Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/7/2006 40 Female 209 lb 5/15/2006 Physician France
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 2/24/2006 31 Male 6/27/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Death 45 Female 8/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 27 Female 8/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 45 Female 9/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 27 Female 9/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/9/2006 57 Male 6/19/2007 Consumer Japan
Primary
Secondary
Opportunistic Infection Hospitalization 2/11/2007 65 Male 157 lb 2/20/2008 Physician France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/16/2007 Female 3/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Hospitalization Male 150 lb 3/26/2008 Consumer United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 71 Female 4/8/2008 Other Health Professional Italy
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 71 Female 4/11/2008 Other Health Professional Italy
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 71 Female 4/14/2008 Italy
Primary
Secondary
Non-hodgkin's Lymphoma Recurrent Other Serious 71 Female 4/16/2008 Italy
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 71 Female 4/29/2008 Consumer Japan
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 1/1/2005 71 Female 4/24/2008 Italy
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 12/1/1995 52 Female 5/5/2008 Consumer Japan
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 1/16/2008 35 Male 5/9/2008 Physician France
Primary
Secondary
Thrombocytopenia Life Threatening 3/22/2007 58 Male 139 lb 5/15/2008 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 3/3/2006 46 Male 148 lb 5/15/2008 Physician France
Primary
Secondary
Thrombocytopenia Other Serious 1/17/2007 56 Female 104 lb 5/15/2008 Physician France
Primary
Secondary
Thrombocytopenia Other Serious 12/23/2006 56 Female 104 lb 5/15/2008 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 5/15/2008 Physician France
Primary
Secondary
Wheezing Other Serious 1/1/2001 58 Male 6/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 58 Male 7/2/2008 United Kingdom
Primary
Secondary
Brain Stem Infarction Death Male 7/16/2008 Other Health Professional Netherlands
Primary
Secondary
Brain Stem Infarction Death Male 7/29/2008 Other Health Professional Japan
Primary
Secondary
Tachycardia Hospitalization 3/1/2007 52 Male 159 lb 7/31/2008 Physician France
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 6/20/2008 Female 8/8/2008 Physician United Kingdom
Primary
Secondary
Large Intestinal Haemorrhage Death 1/1/2005 45 Male 8/12/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 52 Male 159 lb 8/15/2008 Physician France
Primary
Secondary
Amyloidosis Death 1/1/2005 45 Male 8/25/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/12/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Rash Hospitalization 6/20/2008 Female 9/17/2008 Physician United Kingdom
Primary
Secondary
Rash Hospitalization 6/13/2008 Female 10/2/2008 Physician United Kingdom
Primary
Secondary
Hepatitis B Hospitalization 10/3/2007 61 Male 154 lb 10/7/2008 Physician France
Primary
Secondary
Concomitant
Brain Stem Infarction Death Male 10/10/2008 Other Health Professional Netherlands
Primary
Secondary
Vascular Occlusion Other Serious 10/6/2008 40 Female 10/28/2008 Other Health Professional France
Primary
Concomitant
Burkitt's Lymphoma Hospitalization 1/1/2008 66 Male 11/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/16/2008 35 Male 157 lb 10/31/2008 Physician France
Primary
Secondary
Burkitt's Lymphoma Other Serious 1/1/2008 68 Male 11/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Recurrent Other Serious 1/1/2005 71 Female 4/18/2008 Italy
Primary
Secondary
Paraparesis Hospitalization 1/1/2002 40 Male 12/4/2008 Argentina
Primary
Secondary
Spinal Anaesthesia Hospitalization 1/1/2002 40 Male 12/9/2008 Other Health Professional Argentina
Primary
Secondary
Metastases To Bone Marrow Other Serious 58 Male 12/12/2008
Primary
Concomitant
Mucosal Inflammation Hospitalization 11/19/2008 Male 12/16/2008 Consumer United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 3/14/2008 Female 97 lb 12/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 11/20/2008 Male 12/23/2008 Physician United Kingdom
Primary
Secondary
Stem Cell Transplant Death 61 1/21/2009 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death Male 1/21/2009 Other Health Professional United States
Primary
Secondary
Acute Respiratory Failure Other Serious 53 Male 1/29/2009 Italy
Primary
Secondary
Pharyngitis Hospitalization 3/4/2007 28 Female 110 lb 1/28/2009 Physician France
Primary
Secondary
White Blood Cell Count Increased Death 3/3/2006 46 Male 148 lb 1/28/2009 Other Health Professional France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 2/2/2009 Other Health Professional Austria
Primary
Secondary
Treatment Failure Hospitalization 5/19/2006 59 Male 143 lb 1/29/2009 Physician France
Primary
Secondary
Thrombocytopenia Life Threatening 3/22/2007 58 Male 139 lb 1/28/2009 Physician France
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/13/2008 35 Male 157 lb 1/30/2009 Physician France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 2/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myelomonocytic Leukaemia Death 60 Male 2/23/2009 Other Health Professional United States
Primary
Secondary
Coma Hospitalization 45 Male 3/3/2009 Physician Switzerland
Primary
Concomitant
Pancytopenia Other Serious 56 Female 104 lb 4/8/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/9/2006 59 Male 143 lb 4/8/2009 Physician France
Primary
Secondary
Weight Decreased Other Serious 1/14/2007 56 Female 104 lb 4/8/2009 Physician France
Primary
Secondary
Pancytopenia Hospitalization 6/22/2007 43 Male 152 lb 4/14/2009 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 6/22/2007 43 Male 152 lb 4/20/2009 Physician France
Primary
Secondary
Vomiting Hospitalization 3/1/2007 52 Male 159 lb 4/29/2009 Physician France
Primary
Secondary
Pyrexia Other Serious 1/13/2008 35 Male 157 lb 4/29/2009 Physician France
Primary
Secondary
Respiratory Distress Death 3/5/2009 Male 5/20/2009 Physician France
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 1/1/1998 67 Female 6/23/2009 Consumer Japan
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 60 Male 8/11/2009 Other Health Professional Japan
Primary
Secondary
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/11/2009 Physician United Kingdom
Primary
Secondary
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 9/3/2009 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/23/2009 Female 10/9/2009 Physician United Kingdom
Primary
Secondary
Visual Impairment Life Threatening 7/28/2009 Male 10/14/2009 Physician France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 10/29/2009 Physician France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 12/1/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 59 Male 12/10/2009
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 59 Male 12/14/2009
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 73 Male 1/6/2010 Other Health Professional Japan
Primary
Concomitant
Paraesthesia Disability 10/3/2009 Male 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 67 Male 1/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 70 Female 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 56 2/2/2010 Consumer Japan
Primary
Secondary
Febrile Neutropenia Other Serious 61 2/2/2010 Consumer Japan
Primary
Secondary
Ulcer Other Serious 48 Male 2/2/2010 Consumer Japan
Primary
Secondary
Penis Carcinoma Recurrent Other Serious 79 2/2/2010 Consumer Japan
Primary
Secondary
Anaemia Other Serious 56 2/11/2010 Consumer Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 61 Male 2/11/2010 Consumer Japan
Primary
Secondary
Concomitant
Ulcer Other Serious 48 Male 2/11/2010 Consumer Japan
Primary
Secondary
Concomitant
Penis Carcinoma Recurrent Other Serious 79 Male 2/11/2010 Consumer Japan
Primary
Secondary
Concomitant
Post Lumbar Puncture Syndrome Hospitalization 10/13/2009 Female 209 lb 2/17/2010 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 70 Female 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 3/4/2007 28 Female 110 lb 3/8/2010 Physician France
Primary
Secondary
Upper Airway Obstruction Hospitalization 2/11/2007 65 Male 157 lb 3/8/2010 Physician France
Primary
Secondary
Concomitant
Hepatitis B Hospitalization 10/3/2007 61 Male 154 lb 3/26/2010 Physician France
Primary
Secondary
Concomitant
Fat Embolism Other Serious 22 Male 4/2/2010 Other Health Professional Greece
Primary
Secondary
Fat Embolism Hospitalization 22 Male 4/6/2010 Other Health Professional Greece
Primary
Interacting
Fat Embolism Hospitalization 1/1/2010 22 Male 4/8/2010 Other Health Professional Greece
Primary
Secondary
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 5/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 9/29/2007 5/17/2010 Physician France
Primary
Secondary
Upper Airway Obstruction Hospitalization 2/11/2007 65 Male 157 lb 5/14/2010 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/9/2006 59 Male 143 lb 5/17/2010 Physician France
Primary
Secondary
Neutropenia Hospitalization 9/25/2007 29 Male 181 lb 5/17/2010 Physician France
Primary
Secondary
Hepatitis B Hospitalization 10/3/2007 61 Male 154 lb 5/14/2010 Physician France
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 9/25/2007 29 Male 181 lb 5/25/2010 Physician France
Primary
Secondary
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 7/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2010 10/21/2010 Physician Belgium
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 48 Male 12/1/2010 Physician Japan
Primary
Secondary
Malaise Other Serious 48 Male 1/10/2011 Physician Japan
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/15/2010 45 Female 2/24/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Of Central Nervous System Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hormone Level Abnormal Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 36 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Gonadotrophin Abnormal Hospitalization 36 Female 3/9/2011 Physician United Kingdom
Primary
Secondary
Blood Human Chorionic Gonadotropin Positive Other Serious 36 Female 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 36 Female 3/18/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Meningism Hospitalization 36 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 3/21/2011 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Hospitalization 36 Female 3/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Encephalitis Viral Hospitalization 36 Female 3/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoporotic Fracture Other Serious 11 Male 6/28/2011 Other Health Professional Italy
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Death 8/22/2011 Other Health Professional Switzerland
Primary
Secondary
Haemorrhage Death 9/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
Bacterial Sepsis Death 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 9/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Infection Death 9/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 42 Male 10/6/2011 Other Health Professional Italy
Primary
Secondary
Toxicity To Various Agents Death 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Sudden Death Death 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Completed Suicide Death 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data