Methotrexate combined with Zantac

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Hospitalization 3/15/2000 45 Male 194 lb 1/10/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/1/2003 62 Female 115 lb 1/24/2006 Physician United States
Primary
Concomitant
Wound Drainage Hospitalization 1/5/2004 50 Male 2/14/2006 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 10/2/2005 Female 131 lb 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 61 Male 170 lb 2/28/2006 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 6/6/2000 43 Female 205 lb 3/20/2006 Physician United States
Primary
Concomitant
Wound Drainage Hospitalization 1/1/2003 50 Male 220 lb 3/21/2006 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2005 66 Female 3/23/2006 Other Health Professional Belgium
Primary
Concomitant
Thrombosis Hospitalization 6/6/2000 43 Female 205 lb 4/27/2006 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/21/2001 47 Male 148 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Clearance Decreased Required Intervention 2/24/2004 17 Male 152 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 6/1/2005 68 Female 99 lb 7/28/2006 Physician Belgium
Primary
Concomitant
Speech Disorder Hospitalization 7/4/2006 22 Male 196 lb 8/10/2006 Consumer France
Primary
Secondary
Concomitant
Cholecystectomy Hospitalization 10/1/2005 Male 9/11/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/12/2006 Male 121 lb 9/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2006 Male 29 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Mesenteric Vascular Insufficiency Other Serious 5/14/2002 Female 215 lb 10/16/2006 Physician United States
Primary
Concomitant
Weight Increased Required Intervention 9/18/2006 Male 36 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 9/1/2006 Female 44 lb 10/31/2006 Physician United States
Primary
Concomitant
Hyponatraemia Required Intervention 9/5/2006 8 Male 61 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/15/2006 Male 29 lb 11/6/2006 United States
Primary
Secondary
Concomitant
Postoperative Infection Other Serious 12/10/2004 Female 267 lb 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Lower Limb Fracture Other Serious 6/6/2005 Female 267 lb 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/1/2006 Male 11/27/2006 Physician United States
Primary
Concomitant
White Blood Cells Urine Positive Other Serious 8/18/2005 Female 11/28/2006 Lawyer United States
Primary
Concomitant
Lower Limb Fracture Other Serious 6/6/2005 Female 267 lb 12/13/2006 Consumer United Kingdom
Primary
Concomitant
Lymphocytic Lymphoma Other Serious 5/17/2005 Male 164 lb 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Panic Attack 7/26/2006 Female 12/18/2006 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious 6/1/2006 Male 12/29/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 7/25/2006 77 Female 122 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Oesophagitis Ulcerative Hospitalization 12/1/2006 Female 203 lb 4/3/2007 Physician Canada
Primary
Secondary
Concomitant
Pigmentation Disorder Other Serious 7/6/2006 Female 50 lb 4/6/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2007 Female 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/8/2006 Female 50 lb 5/22/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 13 Female 122 lb 6/18/2007 Physician United States
Primary
Concomitant
Osteitis Other Serious 4/1/2006 Male 6/20/2007 Physician Canada
Primary
Concomitant
Dermatitis Psoriasiform 1/1/2007 Male 6/25/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Hospitalization 4/30/2007 Male 6/28/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 8/4/2007 69 Male 284 lb 9/17/2007 Physician United States
Primary
Concomitant
Hyperthyroidism Other Serious 9/1/2007 63 Female 9/25/2007 Consumer United States
Primary
Concomitant
Sepsis Death 7/3/2007 Female 9/25/2007 Physician Greece
Primary
Secondary
Concomitant
Dermatitis Psoriasiform 1/1/2007 72 Male 9/26/2007 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 76 Female 10/4/2007 Consumer United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness 10/16/2007 Female 114 lb 10/22/2007 United States
Primary
Secondary
Concomitant
Menorrhagia Other Serious 1/1/2007 13 Female 10/30/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2005 67 Male 229 lb 11/9/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 8/1/2007 Male 560 lb 11/20/2007 Physician United States
Primary
Concomitant
Menorrhagia Other Serious 3/1/2007 Female 156 lb 12/6/2007 Other Health Professional United States
Primary
Concomitant
Osteopenia Other Serious 1/1/2002 Female 116 lb 12/6/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection 9/25/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 Female 141 lb 12/13/2007 Physician United States
Primary
Concomitant
Staphylococcal Sepsis 12/5/2007 Male 44 lb 12/6/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 12/5/2007 Male 46 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 9/17/2005 Female 267 lb 12/26/2007 Consumer United Kingdom
Primary
Concomitant
Menorrhagia Other Serious 1/1/2007 Female 155 lb 12/26/2007 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Hospitalization 9/17/2005 Female 267 lb 12/27/2007 Consumer United Kingdom
Primary
Concomitant
Viral Infection Other Serious 12/9/2004 Female 141 lb 1/2/2008 Physician United States
Primary
Concomitant
Hemiparesis Hospitalization 12/18/2004 64 Male 2/6/2008 Physician Sweden
Primary
Concomitant
Skin Disorder Other Serious 8/1/2007 Female 2/7/2008 Other Health Professional Canada
Primary
Concomitant
Oedema Peripheral Other Serious 2/4/2008 Female 194 lb 2/27/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 84 lb 3/21/2008 Consumer United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/25/2008 Female 132 lb 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/22/2007 46 Female 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 3/29/2007 69 Female 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 12/6/2007 32 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Abnormal Other Serious 6/5/2006 40 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Abnormal Other Serious 2/14/2007 42 Female 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 1/17/2008 51 Female 4/21/2008 Consumer United States
Primary
Secondary
Concomitant
Radius Fracture Other Serious 1/1/2003 Female 5/2/2008 Lawyer Norway
Primary
Secondary
Concomitant
Medication Residue 3/1/2007 5/13/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/14/2008 Female 70 lb 5/27/2008 United States
Primary
Secondary
Concomitant
Death Other Serious Female 90 lb 6/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms 5/1/2008 58 Female 240 lb 6/30/2008 Other Health Professional United States
Primary
Concomitant
Oesophageal Rupture Other Serious Female 90 lb 7/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Salpingo-oophorectomy Other Serious 2/1/2004 39 Female 229 lb 7/17/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 56 Male 192 lb 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 Male 300 lb 9/12/2008 Consumer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of The Cervix Other Serious 1/1/2002 70 Female 9/28/2008 Other Health Professional Spain
Primary
Concomitant
Muscle Spasms 5/15/2008 58 Female 240 lb 9/25/2008 Other Health Professional United States
Primary
Concomitant
Skin Bacterial Infection Hospitalization 8/24/2007 Female 126 lb 10/28/2008 Physician Japan
Primary
Concomitant
Pallor Other Serious 1/1/2008 Male 169 lb 10/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Skull Fracture Hospitalization 3/16/2005 Female 117 lb 11/11/2008 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Urticaria 1/1/2007 Male 12/1/2008 Physician United States
Primary
Concomitant
Myalgia 1/18/2008 Female 12/1/2008 Physician United States
Primary
Concomitant
Sarcoidosis Hospitalization 8/5/2008 Female 197 lb 12/8/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced 12/17/2007 Female 12/11/2008 Consumer United States
Primary
Concomitant
Respiratory Distress Hospitalization 11/17/2008 Male 154 lb 12/10/2008 United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 67 Female 137 lb 1/13/2009 Consumer United States
Primary
Concomitant
Metastatic Squamous Cell Carcinoma Death Male 143 lb 2/2/2009 United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Viral Dna Test Positive Hospitalization 11/17/2008 Male 154 lb 2/2/2009 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Pyrexia Other Serious 8/1/2006 20 Male 2/20/2009 Other Health Professional Saudi Arabia
Primary
Concomitant
Large Intestine Carcinoma Other Serious 2/1/2008 Female 86 lb 2/26/2009 Physician Japan
Primary
Concomitant
Demyelination Hospitalization 12/20/2008 Female 148 lb 3/4/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/21/2009 Male 190 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 10/1/2008 Female 115 lb 3/16/2009 Physician Puerto Rico
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 3/20/2009 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Other Serious 2/1/2008 Female 86 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2007 Female 180 lb 3/23/2009 Consumer United States
Primary
Concomitant
Ventriculo-peritoneal Shunt Other Serious 10/15/2008 6 Male 4/9/2009 Pharmacist United States
Primary
Concomitant
Venous Thrombosis Hospitalization 6/15/2007 66 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/16/2007 54 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/20/2007 67 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Alanine Aminotransferase Abnormal Other Serious 12/17/2007 50 Female 4/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Death Death Female 5/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestine Carcinoma Other Serious 4/27/2009 Female 121 lb 5/13/2009 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Other Serious 3/31/2008 Female 86 lb 5/19/2009 Physician Japan
Primary
Secondary
Concomitant
Mycobacterium Kansasii Infection 8/1/2008 Male 152 lb 5/19/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 4/1/2008 Male 152 lb 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Carcinoma Other Serious 4/27/2009 Female 121 lb 6/12/2009 Physician Japan
Primary
Secondary
Concomitant
Colitis Hospitalization 4/27/2008 Male 91 lb 7/2/2009 Physician United States
Primary
Concomitant
Colitis Hospitalization 4/27/2008 Male 91 lb 7/9/2009 Physician United States
Primary
Concomitant
Mycobacterium Kansasii Infection 8/1/2008 Male 152 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
Laryngeal Cancer Other Serious 4/15/2009 58 Male 172 lb 8/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 7/27/2009 Male 173 lb 8/14/2009 Other Health Professional United States
Primary
Concomitant
Acute Myocardial Infarction Death Male 8/14/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 83 Female 176 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rosacea Other Serious 10/14/2007 52 Female 158 lb 8/26/2009 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Female 115 lb 9/3/2009 Consumer United States
Primary
Concomitant
Angle Closure Glaucoma Other Serious 1/1/2009 Male 272 lb 9/4/2009 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 6/27/2009 Male 174 lb 9/8/2009 Other Health Professional United States
Primary
Concomitant
Rheumatoid Nodule 1/1/2006 Female 140 lb 9/18/2009 United States
Primary
Concomitant
Pleural Effusion 8/1/2008 Male 152 lb 9/28/2009 Physician United States
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2008 Female 226 lb 10/14/2009 Canada
Primary
Concomitant
Oesophageal Perforation Other Serious 4/1/2009 Female 185 lb 10/16/2009 United States
Primary
Concomitant
Spinal Fracture Life Threatening 3/1/2005 Female 154 lb 11/3/2009 Belgium
Primary
Concomitant
Wound Complication Other Serious 4/27/2009 Female 121 lb 11/10/2009 Physician Japan
Primary
Secondary
Concomitant
Diverticulitis Other Serious 5/1/2009 Female 141 lb 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/7/2008 Female 170 lb 11/20/2009 Physician United States
Primary
Concomitant
Nausea 8/4/2009 Male 77 lb 11/27/2009 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 6/10/2009 Male 246 lb 11/30/2009 Physician United States
Primary
Concomitant
Metastases To Lymph Nodes Other Serious Female 132 lb 12/3/2009 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
Injection Site Swelling 4/7/2009 Female 12/8/2009 Other Health Professional United States
Primary
Concomitant
Sluggishness 5/1/2009 Female 196 lb 12/9/2009 Physician United States
Primary
Concomitant
Intestinal Stenosis Hospitalization 10/2/2009 Male 112 lb 1/15/2010 Other Health Professional United States
Primary
Concomitant
Intestinal Stenosis Hospitalization 10/2/2009 Male 112 lb 1/21/2010 Other Health Professional United States
Primary
Concomitant
Nasal Oedema 9/10/2009 Female 185 lb 1/29/2010 United States
Primary
Concomitant
Myositis 1/1/2009 Male 145 lb 1/30/2010 Physician United States
Primary
Concomitant
Skin Warm 12/9/2009 Female 208 lb 1/30/2010 United States
Primary
Concomitant
Sinus Congestion 12/19/2009 Female 200 lb 1/30/2010 United States
Primary
Concomitant
Colon Cancer Other Serious 3/28/2009 Female 121 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data