Methotrexate combined with Sertraline Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Hospitalization 11/1/2003 44 Male 1/12/2006 Norway
Primary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 3/22/2006 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 5/1/2005 Male 160 lb 4/17/2006 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2003 62 Female 7/13/2006 Consumer Australia
Primary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 6/26/2007 Consumer United States
Primary
Concomitant
Suicide Attempt Hospitalization 10/13/2006 57 Female 7/17/2007 Other Health Professional Sweden
Primary
Concomitant
Renal Impairment Hospitalization 12/4/2006 49 Female 8/10/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 12/4/2006 49 Female 8/10/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tongue Disorder Other Serious 4/1/2004 Female 8/22/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tooth Disorder Hospitalization 45 Female 154 lb 10/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 45 Female 154 lb 3/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Female 185 lb 3/14/2008 United States
Primary
Concomitant
Insomnia 6/4/2008 Female 150 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rash Other Serious 7/1/2008 Male 218 lb 11/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 7/1/2003 Male 271 lb 2/13/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Life Threatening 12/6/2008 Male 4/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2008 Female 188 lb 9/11/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2006 Female 130 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 10/27/2006 Female 177 lb 9/11/2009 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered 3/23/2007 Female 211 lb 9/11/2009 Consumer United States
Primary
Concomitant
Insomnia 6/4/2008 Female 150 lb 9/12/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2008 Female 188 lb 9/14/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2008 Female 188 lb 9/30/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2008 Female 188 lb 11/18/2009 United States
Primary
Concomitant
Depression Death 11/16/2009 Female 12/2/2009 Japan
Primary
Concomitant
Depression Death 11/16/2009 Female 12/14/2009 Japan
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 9/16/2009 74 Female 119 lb 7/15/2010 Other Health Professional Argentina
Primary
Concomitant
Dyskinesia Other Serious Female 5/17/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Weight Increased 1/1/2008 60 Female 142 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Spinal Fracture Other Serious 6/14/2010 69 Female 132 lb 8/6/2010 Physician Canada
Primary
Concomitant
Breast Calcifications Other Serious 5/7/2010 54 Female 143 lb 8/10/2010 Physician Chile
Primary
Secondary
Concomitant
Thrombosis Other Serious 8/1/2009 65 Female 112 lb 8/13/2010 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/4/2009 76 Female 130 lb 8/9/2010 Argentina
Primary
Concomitant
Upper Limb Fracture Other Serious 5/14/2007 58 Female 8/19/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Flushing Female 170 lb 8/27/2010 United States
Primary
Concomitant
Phlebitis Hospitalization 3/22/2010 52 Male 196 lb 8/30/2010 Physician Brazil
Primary
Secondary
Concomitant
Phlebitis Hospitalization 3/22/2010 52 Male 196 lb 9/7/2010 Physician Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/5/2010 58 Female 9/17/2010 Consumer Mexico
Primary
Secondary
Concomitant
Pancreatitis Relapsing Other Serious 1/1/1998 51 Male 179 lb 9/17/2010 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/24/2009 56 Male 163 lb 9/28/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/1/2010 71 Male 138 lb 9/29/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Meningitis Aseptic Hospitalization 11/24/2009 56 Male 163 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/1/2010 71 Male 138 lb 10/14/2010 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 48 Male 11/8/2010
Primary
Secondary
Weight Increased Other Serious 9/23/2010 43 Female 161 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 48 Male 11/12/2010 Other Health Professional United States
Primary
Secondary
Meningitis Aseptic Hospitalization 11/24/2009 56 Male 163 lb 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Pruritus 12/14/2010 Consumer United States
Primary
Concomitant
Irritability 1/9/2009 12/15/2010 Consumer United States
Primary
Concomitant
Tremor 12/17/2009 12/16/2010 Physician United States
Primary
Concomitant
Drug Ineffective 4/23/2010 12/21/2010 Consumer United States
Primary
Concomitant
Injection Site Swelling 6/27/2010 12/22/2010 Physician United States
Primary
Concomitant
Injection Site Haematoma 9/9/2010 12/23/2010 Consumer United States
Primary
Concomitant
Diarrhoea 9/2/2010 53 Female 125 lb 1/29/2011 Consumer United States
Primary
Concomitant
Rash Erythematous 10/1/2010 72 Female 200 lb 1/30/2011 Consumer United States
Primary
Concomitant
Sinusitis 1/1/2007 61 Female 179 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/30/2011 39 Female 243 lb 2/14/2011 Physician Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 2/17/2011 43 Female 141 lb 3/28/2011 Physician France
Primary
Concomitant
Nephrolithiasis Other Serious 3/1/2011 56 Female 225 lb 4/8/2011 Consumer United States
Primary
Concomitant
Otitis Media Other Serious 2/14/2011 63 Female 4/22/2011 Consumer Netherlands
Primary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 62 Female 105 lb 4/26/2011 Physician Japan
Primary
Secondary
Concomitant
Apathy Hospitalization 6/21/2010 70 Female 4/26/2011 Japan
Primary
Concomitant
Apathy Hospitalization Female 5/3/2011 Other Health Professional Japan
Primary
Concomitant
Chronic Myeloid Leukaemia Transformation Life Threatening 62 Female 105 lb 5/13/2011 Physician Japan
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Other Serious 8/1/2009 43 Male 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Pruritus 8/24/2010 64 Female 179 lb 5/17/2011 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 5/11/2011 Other Health Professional Japan
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 10/1/2008 49 Female 163 lb 5/20/2011 Consumer United States
Primary
Secondary
Concomitant
Otitis Media Other Serious 2/12/2011 63 Female 5/23/2011 Consumer Netherlands
Primary
Concomitant
Dementia Alzheimer's Type Hospitalization 6/21/2010 70 Female 5/25/2011 Physician Japan
Primary
Concomitant
Discomfort Other Serious 170 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 6/1/2007 30 Female 180 lb 5/27/2011 Consumer United States
Primary
Secondary
Concomitant
Sensory Loss Other Serious 1/1/2009 55 Female 179 lb 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ovarian Cancer Hospitalization 1/1/2009 Female 6/1/2011 Physician Portugal
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Transformation Hospitalization 4/14/2011 62 Female 107 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Transformation Hospitalization 4/7/2011 62 Female 107 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 2/2/2011 87 Female 176 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 6/7/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 1/30/2011 39 Female 243 lb 6/7/2011 Physician Australia
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 2/12/2011 33 Female 140 lb 5/11/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Injury Other Serious 7/1/2003 42 Female 200 lb 6/9/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 52 Female 146 lb 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 52 Female 146 lb 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 6/15/2011 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 6/20/2011 Physician Japan
Primary
Concomitant
Cataract Other Serious Female 137 lb 6/23/2011 Other Health Professional Canada
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/21/2010 70 Female 7/6/2011 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 4/1/2011 72 Female 205 lb 7/19/2011 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 55 Female 174 lb 7/26/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/1/2011 26 Male 8/1/2011 Other Health Professional Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 10/1/2010 71 Female 115 lb 8/4/2011 Consumer United States
Primary
Concomitant
Dry Skin Other Serious 52 Female 146 lb 8/24/2011 Consumer United States
Primary
Secondary
Concomitant
Umbilical Hernia Other Serious 1/1/2001 72 Female 8/29/2011 Consumer United States
Primary
Concomitant
Local Swelling Other Serious 1/1/2011 72 Female 8/30/2011 Consumer United States
Primary
Concomitant
Chest Pain Other Serious Female 157 lb 9/1/2011 Other Health Professional Canada
Primary
Concomitant
Dehydration Other Serious 5/1/2008 63 Female 125 lb 9/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious Female 157 lb 9/27/2011 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 2/17/2011 43 Female 141 lb 10/7/2011 Physician France
Primary
Concomitant
Headache Other Serious 2/17/2011 43 Female 141 lb 10/7/2011 Physician Tunisia
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 10/19/2011 Physician United States
Primary
Secondary
Concomitant
Parkinsonism Hospitalization 6/11/2011 41 Female 157 lb 10/25/2011 Physician Japan
Primary
Secondary
Concomitant
Paraesthesia 11/1/2010 67 Female 10/30/2011 Physician United States
Primary
Concomitant
Anaemia Other Serious 48 Female 10/27/2011 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain Female 180 lb 11/3/2011 Consumer United States
Primary
Concomitant
Haemorrhage Female 11/3/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Rash 7/29/2011 47 Female 182 lb 11/3/2011 Other Health Professional United States
Primary
Concomitant
Anaemia Hospitalization 8/5/2010 Female 119 lb 11/7/2011 Consumer Mexico
Primary
Secondary
Concomitant
Injection Site Reaction Other Serious 8/29/2011 62 Female 11/7/2011 Pharmacist United States
Primary
Concomitant
Pain Other Serious 8/10/2009 29 Female 151 lb 11/11/2011 Other Health Professional United States
Primary
Concomitant
Psychological Trauma Other Serious 8/10/2009 29 Female 151 lb 11/11/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Warmth 1/17/2011 75 Female 130 lb 11/17/2011 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2006 35 Female 90 lb 11/23/2011 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2011 72 Female 12/8/2011 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/3/2011 81 Female 238 lb 12/13/2011 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 12/13/2011 Physician United States
Primary
Secondary
Concomitant
Ovarian Cyst Hospitalization 1/1/2010 38 Female 106 lb 12/20/2011 Consumer Brazil
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 48 Female 12/22/2011 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/13/2011 74 Female 134 lb 12/27/2011 Other Health Professional Canada
Primary
Concomitant
Gait Disturbance Other Serious 8/30/2010 68 Female 132 lb 12/28/2011 Brazil
Primary
Concomitant
Rash 7/1/2011 58 Female 230 lb 1/28/2012 Consumer United States
Primary
Concomitant
Drug Dose Omission 1/1/2011 60 Female 1/27/2012 Consumer United States
Primary
Concomitant
Cough Female 188 lb 1/27/2012 Consumer United States
Primary
Concomitant
Blood Pressure Increased 12/1/2010 56 Female 162 lb 1/27/2012 Consumer United States
Primary
Concomitant
Arthralgia 12/3/2010 72 Female 195 lb 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Nodule 12/1/2010 49 Female 140 lb 1/27/2012 Consumer United States
Primary
Concomitant
Arthralgia Hospitalization 2/25/2011 72 Female 1/27/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 9/1/2010 61 Female 140 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 5/4/2011 65 Male 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haematoma 4/4/2011 68 Female 1/28/2012 Consumer United States
Primary
Concomitant
Increased Upper Airway Secretion Hospitalization 1/1/2008 71 Female 207 lb 1/28/2012 Consumer United States
Primary
Concomitant
Flatulence 12/15/2011 60 Female 1/29/2012 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 9/1/2011 58 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema 9/12/2011 10 Female 1/28/2012 Consumer United States
Primary
Concomitant
Arthralgia Disability 5/1/2010 58 Female 247 lb 2/3/2012 Consumer Brazil
Primary
Concomitant
Sepsis Hospitalization 12/3/2011 81 Female 238 lb 2/29/2012 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 1/21/2012 45 Male 220 lb 2/24/2012 Consumer United States
Primary
Concomitant
Lung Disorder Other Serious Male 212 lb 3/14/2012 Canada
Primary
Concomitant
Amnesia Other Serious 1/1/2012 40 Female 143 lb 3/27/2012 Consumer Brazil
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/16/2012 65 Female 3/29/2012 Consumer Canada
Primary
Concomitant
Influenza Like Illness 2/1/2012 57 Female 4/2/2012 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 1/1/2009 41 Female 3/22/2012 Consumer United States
Primary
Concomitant

Drug Data