Flexeril combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Artery Stent Placement Hospitalization 4/1/2005 Female 1/3/2006 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 9/1/2005 63 Female 1/5/2006 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 12/22/2005 Female 177 lb 1/12/2006 Other Health Professional United States
Primary
Concomitant
Tongue Disorder Hospitalization 9/28/2005 75 Female 115 lb 11/19/2005 Pharmacist United States
Primary
Concomitant
Sciatica Hospitalization 9/1/2005 63 Female 1/17/2006 United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 12/22/2005 Female 185 lb 2/15/2006 Other Health Professional United States
Primary
Concomitant
Rash 3/29/2005 50 Female 239 lb 2/15/2006 Consumer United States
Primary
Concomitant
Insomnia 6/1/2005 56 Female 155 lb 1/5/2006 Consumer United States
Primary
Concomitant
Anaphylactic Shock Required Intervention 2/1/2006 27 Female 160 lb 2/23/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 61 Male 170 lb 2/27/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 170 lb 2/28/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2002 Female 131 lb 4/7/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Death 8/21/2003 60 Female 170 lb 4/27/2006 Lawyer United States
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 5/5/2006 Physician United States
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 5/19/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Male 5/25/2006 Physician United States
Primary
Concomitant
Shock Other Serious 4/1/2006 Male 209 lb 6/26/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 6/13/2006 33 Female 214 lb 6/28/2006 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Required Intervention 5/1/2006 Male 143 lb 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 6/13/2006 33 Female 214 lb 8/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/13/2006 33 Female 214 lb 8/3/2006 Physician United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 8/28/2006 Other Health Professional United States
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 69 Female 8/23/2006 Physician United States
Primary
Concomitant
Thyroiditis Hospitalization 1/1/2006 Female 210 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Postoperative Infection Other Serious 1/1/2003 Male 310 lb 9/14/2006 Physician United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 8/29/2006 Female 149 lb Physician United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/18/2006 Female 140 lb 10/19/2006 Other Health Professional United States
Primary
Concomitant
Facial Palsy Disability 1/1/2006 60 Female 12/8/2006 Consumer United States
Primary
Concomitant
Nasopharyngitis 9/5/2006 Female 12/19/2006 Physician United States
Primary
Concomitant
Arteriosclerosis Death Female 154 lb 2/1/2007 Physician United States
Primary
Concomitant
Spinal Column Stenosis Other Serious 11/1/2005 Female 183 lb 2/2/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2005 Female 183 lb 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Throat Cancer Other Serious 5/1/2006 Female 3/1/2007 Physician United States
Primary
Concomitant
Throat Cancer Other Serious 5/1/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 6/24/2005 Male 204 lb 4/17/2007 Physician United States
Primary
Concomitant
Neuralgia Other Serious 7/1/2006 Female 148 lb 7/17/2007 Consumer United States
Primary
Concomitant
Bradycardia Hospitalization 7/5/2007 Female 176 lb 7/18/2007 Other Health Professional United States
Primary
Concomitant
Perirectal Abscess Other Serious 3/13/2007 Male 224 lb 7/30/2007 Physician United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2007 Female 185 lb 8/13/2007 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 12/5/2004 70 Female 7/9/2007 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 67 Female 108 lb 6/8/2007 Consumer United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Rash 7/24/2007 Female 132 lb 9/26/2007 Consumer United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/5/2007 Female 176 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 7/2/2007 Female 176 lb 10/26/2007 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2003 67 Female 11/2/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2003 67 Female 11/5/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2002 67 Female 11/14/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2002 67 Female 11/21/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2006 Female 148 lb 12/7/2007 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 3/1/2007 Female 200 lb 12/8/2007 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection 9/25/2006 Female 12/10/2007 Physician United States
Primary
Concomitant
Nasopharyngitis 3/24/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Injection Site Reaction 7/1/2007 Female 12/13/2007 Consumer United States
Primary
Concomitant
Swelling 7/5/2007 Female 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 6/1/2007 Male 186 lb 12/13/2007 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2002 67 Female 12/14/2007 Physician United States
Primary
Concomitant
Musculoskeletal Stiffness 8/1/2007 Female 135 lb 12/13/2007 Physician United States
Primary
Concomitant
Somnolence 9/1/2007 Female 162 lb 12/13/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 11/1/2007 Female 204 lb 12/27/2007 Physician United States
Primary
Concomitant
Rash Other Serious 8/15/2007 Female 1/2/2008 Consumer United States
Primary
Concomitant
Usher's Syndrome Other Serious 11/1/2007 Female 1/2/2008 Physician United States
Primary
Concomitant
Rash Other Serious 8/15/2007 Female 114 lb 1/22/2008 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2002 67 Female 2/22/2008 Physician United States
Primary
Concomitant
Drug Ineffective 8/1/2007 210 lb 3/15/2008 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 67 Female 3/18/2008 Physician United States
Primary
Concomitant
Thrombosis Other Serious Male 3/24/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 3/25/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 Female 143 lb 4/8/2008 Physician United States
Primary
Concomitant
Raynaud's Phenomenon 2/1/2006 54 Female 4/3/2007 Physician United States
Primary
Concomitant
B-cell Lymphoma Stage Iii Other Serious 1/1/2008 Female 232 lb 4/28/2008 Other Health Professional United States
Primary
Concomitant
Weight Fluctuation Other Serious 12/17/2007 Female 5/2/2008 Physician United States
Primary
Concomitant
B-cell Lymphoma Stage Iii Other Serious 1/1/2008 Female 232 lb 5/12/2008 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 6/16/2005 Female 225 lb 6/10/2008 Physician United States
Primary
Concomitant
Nausea 1/1/2007 38 Female 170 lb 6/30/2008 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 5/19/2004 Female 184 lb 8/8/2008 Physician United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 4/30/2007 68 Female 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 8/14/2008 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 150 lb 8/18/2008 Consumer United States
Primary
Concomitant
Pain Other Serious Female 150 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 7/3/2008 Female 9/12/2008 United States
Primary
Concomitant
Death Death Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 143 lb 10/27/2008 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 143 lb 11/5/2008 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Other Serious 10/14/2008 Female 106 lb 11/7/2008 United States
Primary
Concomitant
Urticaria Hospitalization 1/20/2007 Female 143 lb 11/14/2008 Other Health Professional United States
Primary
Concomitant
Asthma Other Serious 4/30/2007 68 Female 11/26/2008 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Stress Fracture Hospitalization 9/1/2007 Female 12/8/2008 Physician United States
Primary
Concomitant
Stress 3/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Red Cell Distribution Width Increased 1/1/2005 Female 200 lb 12/12/2008 Consumer United States
Primary
Concomitant
Visual Impairment 4/1/2008 Female 250 lb 12/12/2008 United States
Primary
Concomitant
Nasopharyngitis 10/2/2008 Female 128 lb 12/12/2008 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 6/1/2008 Female 133 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Pain Female 132 lb 12/12/2008 Consumer United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 11/29/2008 Female 12/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 66 Female 12/22/2008 Physician United States
Primary
Concomitant
Rash Other Serious 10/1/2007 Female 114 lb 1/23/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 2/13/2009 Other Health Professional Canada
Primary
Concomitant
Prostate Cancer Other Serious 10/20/2008 Male 174 lb 2/13/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 2/24/2009 Other Health Professional Canada
Primary
Concomitant
Prostate Cancer Other Serious 10/20/2008 Male 174 lb 3/2/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 3/13/2009 Other Health Professional Canada
Primary
Concomitant
Swelling 9/10/2008 Female 240 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased 10/1/2008 Female 194 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
Macular Degeneration Hospitalization 1/1/2008 Female 134 lb 3/14/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 9/1/2007 Female 200 lb 3/14/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 2/1/2009 Female 159 lb 3/14/2009 United States
Primary
Concomitant
Urticaria 11/27/2008 58 Female 3/14/2009 Other Health Professional
Primary
Concomitant
Cardiac Failure Congestive Other Serious 10/1/2008 Female 115 lb 3/16/2009 Physician Puerto Rico
Primary
Concomitant
Vaginal Fistula Other Serious 1/1/2008 Female 118 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 1/1/2008 Female 118 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 7/1/2008 Female 182 lb 3/27/2009 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2009 69 Female 3/31/2009 Physician United States
Primary
Concomitant
Anal Fistula Hospitalization 8/1/2008 Male 190 lb 4/22/2009 Other Health Professional Canada
Primary
Concomitant
Pain In Extremity Other Serious 1/25/2009 Female 294 lb 4/29/2009 Other Health Professional Canada
Primary
Concomitant
Aggression Other Serious 1/1/2008 Female 120 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Anal Fistula Hospitalization 8/1/2008 Male 190 lb 5/7/2009 Other Health Professional Canada
Primary
Concomitant
Shoulder Arthroplasty Other Serious 4/1/2009 Female 5/7/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 8/1/2008 Female 234 lb 5/19/2009 Physician Canada
Primary
Concomitant
Tachypnoea Other Serious 59 Female 5/26/2009 Lawyer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/11/2009 Female 150 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Insulin-requiring Type 2 Diabetes Mellitus Other Serious 4/29/2002 50 Female 388 lb 6/1/2009 United States
Primary
Concomitant
Accidental Exposure 9/7/2008 Female 140 lb 6/11/2009 United States
Primary
Concomitant
Red Cell Distribution Width Increased 1/1/2005 Female 200 lb 6/11/2009 Consumer United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 6/11/2009 Consumer United States
Primary
Concomitant
Paraesthesia 7/1/2008 Male 237 lb 6/11/2009 United States
Primary
Concomitant
Nasopharyngitis 10/2/2008 Female 128 lb 6/11/2009 United States
Primary
Concomitant
Eye Swelling Other Serious 3/1/2009 Female 163 lb 6/11/2009 Other Health Professional United States
Primary
Concomitant
Swelling 4/1/2009 Female 246 lb 6/12/2009 United States
Primary
Concomitant
Tachypnoea Other Serious 8/30/2007 59 Female 6/25/2009 Physician United States
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 5/10/2009 6/30/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/12/2009 40 Male 143 lb 7/6/2009 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 4/22/2009 Female 241 lb 7/14/2009 Physician United States
Primary
Concomitant
Generalised Oedema Hospitalization 6/23/2009 Female 316 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms 4/1/2009 Female 7/24/2009 Physician United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2007 Female 127 lb 7/31/2009 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/10/2009 Female 7/31/2009 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 7/5/2009 Female 251 lb 8/21/2009 Other Health Professional Canada
Primary
Concomitant
Hot Flush Female 8/22/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 8/1/2009 Female 145 lb 8/26/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral 5/1/2009 48 Female 8/14/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2009 Female 162 lb 9/4/2009 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2008 Female 188 lb 9/11/2009 United States
Primary
Concomitant

Drug Data