Folate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Breast Cancer Other Serious 11/17/2005 Female 175 lb 1/5/2006 Other Health Professional United States
Primary
Concomitant
Sputum Purulent Other Serious 7/5/2005 61 Female 2/21/2006 Physician Australia
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 57 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Disease Death Female 3/1/2006 Physician United States
Primary
Concomitant
Sputum Purulent Other Serious 7/5/2005 61 Female 98 lb 3/2/2006 Physician Australia
Primary
Secondary
Concomitant
Drug Level Decreased Death Female 3/15/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Death 74 Female 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Optic Neuritis Retrobulbar Hospitalization 55 Male 4/7/2006 United States
Primary
Concomitant
Adenocarcinoma Other Serious 5/5/2006 Physician United States
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 4/1/2005 Female 150 lb 5/26/2006 Physician United States
Primary
Concomitant
Cough Disability 6/1/2005 58 Female 5/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia Disability 4/5/2006 72 Female 146 lb 5/31/2006 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 70 Male 6/7/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Sarcoidosis Other Serious 6/1/2001 62 Female 6/14/2006 Consumer United States
Primary
Concomitant
B-cell Lymphoma Stage I Other Serious 8/4/2004 Female 128 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
B-cell Lymphoma Stage I Other Serious 8/4/2004 Female 128 lb 8/1/2006 Other Health Professional United States
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 6/30/2006 59 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/20/2006 71 Female 9/6/2006 Physician United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 8/29/2006 Female 149 lb Physician United States
Primary
Concomitant
Kaposi's Sarcoma Other Serious 8/1/2005 Female 121 lb 10/6/2006 Physician United States
Primary
Concomitant
B-cell Lymphoma Other Serious 1/1/2003 Female 11/8/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 11/6/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 8/14/2006 Male 160 lb 12/4/2006 Physician United States
Primary
Concomitant
Hypertension Hospitalization 11/9/2006 55 Male 190 lb 12/15/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/25/2006 77 Female 122 lb 12/22/2006 Pharmacist United States
Primary
Concomitant
Vasculitis Other Serious 10/1/2001 Female 1/26/2007 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Death 8/24/2005 74 Female 1/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Histoplasmosis Disseminated Other Serious 8/11/2006 Female 124 lb 2/8/2007 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 10/14/2005 Female 106 lb 3/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Palpitations 61 Female 229 lb 3/27/2007 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 9/1/2006 62 Female 5/3/2007 Physician United States
Primary
Concomitant
Urticaria Life Threatening 44 Female 7/18/2007 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 6/8/2007 Female 115 lb 8/23/2007 Physician Canada
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious Female 10/8/2007 Physician United Kingdom
Primary
Concomitant
Myalgia Hospitalization 6/8/2007 Female 115 lb 12/3/2007 Physician Canada
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Viral Infection Other Serious 4/1/2007 64 Female 107 lb 1/30/2008 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 4/1/2007 Female 107 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/25/2008 Female 132 lb 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 12/17/2005 Female 83 lb 5/30/2008 Physician Australia
Primary
Concomitant
Fracture Other Serious 1/1/2003 79 Female 154 lb 6/4/2008 Physician Germany
Primary
Concomitant
Osteopenia Other Serious 4/1/2007 64 Female 6/30/2008 Physician United States
Primary
Concomitant
Chemical Poisoning Other Serious 10/15/2007 70 Male 198 lb 6/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 6/27/2008 Physician United States
Primary
Concomitant
Thrombosis Other Serious 53 Male 7/16/2008 Other Health Professional Portugal
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 9/1/2006 62 Female 220 lb 7/15/2008 United States
Primary
Concomitant
Pancytopenia Other Serious 8/11/2006 Female 124 lb 7/22/2008 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2006 62 Female 220 lb 7/24/2008 United States
Primary
Concomitant
Vomiting Other Serious 7/18/2008 42 Female 8/1/2008 Other Health Professional Germany
Primary
Concomitant
Meningitis Tuberculous Hospitalization 11/8/2006 Female 170 lb 8/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocarditis Other Serious 10/19/2007 39 Male 176 lb 8/8/2008 Physician Germany
Primary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 4/30/2007 68 Female 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/18/2008 42 Female 10/3/2008 Other Health Professional Germany
Primary
Concomitant
Pneumonia Other Serious Female 168 lb 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Latent Tuberculosis Death Female 11/17/2008 Other Health Professional United States
Primary
Concomitant
Asthma Other Serious 4/30/2007 68 Female 11/26/2008 Consumer United States
Primary
Secondary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 11/27/2008 Physician United States
Primary
Concomitant
Alopecia 5/1/2008 68 Female 12/17/2008 United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 12/19/2008 Physician United States
Primary
Concomitant
Pneumonitis Death 4/11/2008 58 Male 1/26/2009 Physician Malaysia
Primary
Concomitant
Prostate Cancer Other Serious 10/20/2008 Male 174 lb 2/13/2009 Physician United States
Primary
Concomitant
Crohn's Disease Hospitalization 2/2/2009 Female 115 lb 2/20/2009 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 8/1/2001 62 Female 218 lb 2/23/2009 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 10/20/2008 Male 174 lb 3/2/2009 Physician United States
Primary
Concomitant
Crohn's Disease Hospitalization 2/3/2009 Female 115 lb 3/3/2009 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 11/1/2008 Female 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage 1/3/2009 Female 110 lb 3/14/2009 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 11/1/2008 Female 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 3/1/2009 33 Female 4/13/2009 Physician United States
Primary
Concomitant
Tenosynovitis Hospitalization 3/27/2009 65 Female 192 lb 5/20/2009 Physician United States
Primary
Concomitant
Tibia Fracture Hospitalization 4/13/2009 Female 112 lb 8/14/2009 Physician United States
Primary
Concomitant
Crohn's Disease Hospitalization 5/11/2009 Female 107 lb 8/14/2009 Other Health Professional United States
Primary
Concomitant
Crohn's Disease Hospitalization 5/11/2009 Female 107 lb 8/28/2009 Other Health Professional United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2009 Female 198 lb 11/17/2009 Physician Netherlands
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 9/28/2009 Female 198 lb 11/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 10/28/2009 56 Female 11/25/2009 Other Health Professional Spain
Primary
Concomitant
Breast Cancer Female Other Serious 11/9/2009 60 Female 168 lb 11/25/2009 Hungary
Primary
Concomitant
Breast Cancer Stage Ii Other Serious 11/3/2009 Female 168 lb 12/12/2009 Other Health Professional Hungary
Primary
Concomitant
Pain Other Serious 11/3/2009 Female 168 lb 12/23/2009 Other Health Professional Hungary
Primary
Concomitant
Tuberculosis Other Serious Female 150 lb 1/7/2010 Consumer South Africa
Primary
Concomitant
Weight Decreased Hospitalization 12/14/2009 Female 18 lb 1/8/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 12/14/2009 Female 18 lb 1/21/2010 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/17/2009 62 Female 142 lb 1/21/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Polyarthritis Hospitalization 12/1/2009 Female 2/8/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Respiratory Syncytial Viral Hospitalization 2/2/2010 Female 18 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/1/2001 62 Female 218 lb 2/25/2010 Physician United States
Primary
Concomitant
Pneumonia Respiratory Syncytial Viral Hospitalization 2/2/2010 Female 18 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Life Threatening 1/13/2010 Male 168 lb 3/12/2010 Other Health Professional South Africa
Primary
Concomitant
Pain Other Serious 11/3/2009 Female 168 lb 3/24/2010 Hungary
Primary
Concomitant
Pyrexia Hospitalization 3/20/2010 2 Female 18 lb 4/2/2010 Physician United States
Primary
Concomitant
Polyarthritis Hospitalization 12/1/2009 35 Female 4/12/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 3/20/2010 2 Female 18 lb 4/16/2010 Physician United States
Primary
Concomitant
Herpes Virus Infection Other Serious 12/1/2009 64 Male 209 lb 4/23/2010 Physician South Africa
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 3/24/2010 67 Female 115 lb 4/26/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Disseminated Tuberculosis Hospitalization 4/22/2010 67 Female 115 lb 5/21/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 11/1/2008 41 Female 5/21/2010 Physician United States
Primary
Concomitant
Disseminated Tuberculosis Hospitalization 4/22/2010 67 Female 115 lb 5/27/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 3/24/2010 67 Female 115 lb 6/14/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Lip Swelling Other Serious 5/21/2010 24 Female 6/17/2010 Other Health Professional South Africa
Primary
Concomitant
Disseminated Tuberculosis Hospitalization 4/22/2010 67 Female 115 lb 6/18/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Legionella Other Serious 1/14/2005 63 Male 183 lb 6/28/2010 Physician Germany
Primary
Concomitant
Septic Shock Hospitalization 4/22/2010 67 Female 115 lb 7/7/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 3/24/2010 67 Female 115 lb 7/7/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 58 7/11/2010 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 2/23/2010 44 Female 217 lb 7/13/2010 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 4/22/2010 67 Female 115 lb 7/16/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Myopathy Other Serious 3/11/2010 46 Male 8/3/2010 Physician United Kingdom
Primary
Concomitant
Nausea Death 7/21/2010 67 Female 385 lb 8/23/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 2/16/2010 44 Female 217 lb 9/16/2010 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 11/1/2008 41 Female 9/23/2010 Physician United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 9/25/2010 50 Female 110 lb 10/7/2010 Physician Singapore
Primary
Concomitant
Wound Dehiscence Other Serious 10/20/2008 63 Male 222 lb 10/14/2010 Physician United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 9/25/2010 50 Female 110 lb 10/15/2010 Physician Singapore
Primary
Concomitant
Wound Dehiscence Other Serious 10/20/2008 63 Male 222 lb 10/15/2010 Physician United States
Primary
Concomitant
Pneumonia Death 9/24/2010 75 Female 10/21/2010 Physician United States
Primary
Concomitant
Crohn's Disease Hospitalization 8/17/2010 11 Female 70 lb 10/29/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 8/1/2010 72 Female 200 lb 11/4/2010 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 9/26/2010 66 Male 188 lb 12/10/2010 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 9/26/2010 66 Male 188 lb 12/17/2010 Physician Brazil
Primary
Concomitant
Pyrexia Hospitalization 3/20/2010 2 Female 18 lb 1/6/2011 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2008 64 Female 103 lb 1/11/2011 Other Health Professional Canada
Primary
Concomitant
Eye Disorder Other Serious 3/1/2009 49 Male 1/29/2011 Physician United States
Primary
Concomitant
Dermatitis Bullous 10/29/2010 62 Male 160 lb 1/30/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2006 84 Female 110 lb 1/30/2011 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/1/2010 46 Female 1/30/2011 Consumer United States
Primary
Concomitant
Drug Effect Decreased Hospitalization 12/1/2010 70 Male 195 lb 3/14/2011 Physician United States
Primary
Concomitant
Vomiting 2/26/2011 82 Female 3/25/2011 Consumer United States
Primary
Concomitant
Nausea Death 7/21/2010 67 Female 385 lb 4/19/2011 Other Health Professional United States
Primary
Concomitant
Glaucoma Other Serious 2/24/2010 80 Female 126 lb 4/27/2011 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 11/1/2008 41 Female 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Bronchiolitis Hospitalization 2/2/2011 3 Female 18 lb 5/24/2011 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 4/14/2011 50 Female 5/26/2011 Physician Austria
Primary
Concomitant
Bursitis Hospitalization 4/30/2010 71 Female 134 lb 5/26/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Respiratory Disorder Hospitalization 12/1/2004 76 Female 6/2/2011 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 11/1/2008 41 Female 6/7/2011 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/1/2011 37 Male 183 lb 6/9/2011 Other Health Professional United States
Primary
Concomitant
Feeling Abnormal Other Serious 1/1/2010 Female 7/1/2011 Consumer Korea, Republic Of
Primary
Concomitant
Upper-airway Cough Syndrome 6/26/2011 56 Female 180 lb 2/4/2013 Consumer Us
Primary
Concomitant
Premature Delivery Hospitalization 3/28/2011 29 Female 189 lb 9/21/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Splenomegaly Other Serious Male 11/29/2012 Physician Au
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2012 70 Female 8/28/2012 Physician Country Not Specified
Primary
Concomitant
Crohn's Disease Hospitalization 7/24/2012 18 Female 121 lb 9/13/2012 Physician Us
Primary
Concomitant
Post Procedural Complication Hospitalization 2011 51 Female 240 lb 12/27/2012 Physician Us
Primary
Concomitant
Tremor Other Serious 2/13/2006 63 Female 202 lb 10/25/2012 Physician Us
Primary
Concomitant
Scratch Hospitalization 9/30/2012 59 Male 240 lb 12/6/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 9/2012 Female 113 lb 12/11/2012 Consumer Us
Primary
Concomitant
Visual Acuity Reduced Other Serious 2010 Female 126 lb 12/26/2012 Consumer Us
Primary
Secondary
Concomitant

Drug Data