Methotrexate combined with Propranolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Cancer Other Serious 1/1/2005 Female 154 lb 1/3/2006 Physician United States
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2005 Female 128 lb 1/27/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 5/24/2005 51 Female 3/14/2006 Brazil
Primary
Secondary
Concomitant
Skin Cancer Other Serious 10/1/2005 Female 7/10/2006 Physician United States
Primary
Concomitant
Malignant Anorectal Neoplasm Other Serious 7/11/2005 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 8/16/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2004 Female 9/6/2006 Physician United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 6/1/2005 Female 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
Diverticulitis Death Female 1/25/2007 Physician United States
Primary
Concomitant
Ulcer Other Serious 7/5/2006 Female 119 lb 1/27/2007 Consumer Brazil
Primary
Concomitant
Leiomyosarcoma Other Serious 11/10/2004 Female 157 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Leiomyosarcoma Other Serious 11/10/2004 Female 157 lb 6/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 21 Female 7/5/2007 Other Health Professional Saudi Arabia
Primary
Secondary
Rash Generalised Hospitalization 9/7/2007 Female 9/18/2007 Physician Singapore
Primary
Concomitant
Rash Generalised Hospitalization 9/7/2007 Female 10/2/2007 Physician Singapore
Primary
Concomitant
Drug Ineffective 5/1/2007 Female 12/12/2007 Other Health Professional United States
Primary
Concomitant
Accidental Exposure 10/1/2007 Female 235 lb 12/14/2007 Consumer United States
Primary
Concomitant
Ear Infection 10/27/2007 Male 188 lb 12/14/2007 United States
Primary
Concomitant
Weight Decreased 12/22/2006 Male 229 lb 12/15/2007 Physician United States
Primary
Concomitant
Infection Hospitalization 7/11/2007 Female 154 lb 1/18/2008 United Kingdom
Primary
Concomitant
Ovarian Cancer Death 8/1/2005 Female 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 3/1/2006 Female 250 lb 5/20/2008 United States
Primary
Concomitant
Varices Oesophageal 9/20/2006 53 Male 2/21/2008 Physician United States
Primary
Concomitant
Death Death Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Pseudoporphyria Other Serious 65 Female 11/25/2008 Physician United States
Primary
Concomitant
Hallucination 6/6/2008 Female 12/12/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 27 Female 12/12/2008 Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 27 Female 12/30/2008 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection 10/25/2008 Female 3/14/2009 United States
Primary
Concomitant
Fall Death 11/17/2008 79 Female 106 lb 3/26/2009 Pharmacist United States
Primary
Concomitant
Rales Other Serious 7/9/2008 Female 132 lb 4/2/2009 United Kingdom
Primary
Concomitant
Thrombotic Stroke Hospitalization 10/1/2008 Female 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ovarian Cancer Other Serious 6/1/2006 Female 123 lb 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ill-defined Disorder 5/1/2009 Female 170 lb 6/12/2009 Consumer United States
Primary
Concomitant
Nodule Other Serious Female 176 lb 9/11/2009 Brazil
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/3/2006 Female 142 lb 9/11/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 7/1/2007 Female 189 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 10/1/2007 Female 235 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pain Other Serious Female 154 lb 10/15/2009 Brazil
Primary
Concomitant
Nodule Other Serious Female 176 lb 10/27/2009 Brazil
Primary
Concomitant
Pulmonary Fibrosis Other Serious 10/21/2008 Female 196 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pituitary Tumour Other Serious 5/1/2008 Female 146 lb 11/18/2009 United Kingdom
Primary
Concomitant
Pituitary Tumour Benign Other Serious 5/1/2008 51 Female 146 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rib Fracture 6/17/2008 Female 194 lb 12/3/2009 Physician United States
Primary
Concomitant
Tendon Rupture 10/1/2007 Female 12/10/2009 Physician United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2009 Female 174 lb 12/10/2009 Brazil
Primary
Concomitant
Syncope Other Serious 6/10/2009 Female 128 lb 12/23/2009 Brazil
Primary
Concomitant
Throat Tightness Other Serious 8/9/2004 Female 180 lb 12/29/2009 Consumer United States
Primary
Concomitant
Colonic Stenosis Hospitalization 1/8/2010 Female 1/21/2010 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 57 Male 1/22/2010 Physician Israel
Primary
Secondary
Concomitant
Insomnia 49 Female 1/24/2010 Consumer United States
Primary
Concomitant
Vein Disorder Other Serious 1/1/2004 Female 258 lb 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2009 Female 220 lb 1/25/2010 Brazil
Primary
Secondary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2009 Female 154 lb 1/28/2010 Brazil
Primary
Concomitant
Injection Site Reaction 5/1/2004 Female 205 lb 1/30/2010 United States
Primary
Concomitant
Drug Ineffective 60 Female 165 lb 2/22/2010 Consumer United States
Primary
Concomitant
Colon Cancer Hospitalization 10/29/2009 Female 3/19/2010 United States
Primary
Concomitant
Pain Other Serious 1/30/2010 Female 154 lb 3/22/2010 Brazil
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 4/14/2009 51 Female 4/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 6/1/2009 66 Female 255 lb 4/6/2010 Physician United States
Primary
Concomitant
Death Death Female 4/6/2010 Physician United Kingdom
Primary
Concomitant
Vulvovaginal Human Papilloma Virus Infection Other Serious 1/1/2009 61 Female 161 lb 4/21/2010 Brazil
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 8/1/2009 48 Female 183 lb 4/23/2010 Brazil
Primary
Concomitant
Lung Neoplasm Other Serious 6/1/2009 66 Female 255 lb 4/30/2010 Physician United States
Primary
Concomitant
Colon Cancer Hospitalization 10/29/2009 80 Female 5/4/2010 United States
Primary
Concomitant
Vulvovaginal Human Papilloma Virus Infection Other Serious 1/1/2009 61 Female 161 lb 5/6/2010 Brazil
Primary
Concomitant
Inflammation Hospitalization 9/1/2009 68 Male 176 lb 5/10/2010 United States
Primary
Concomitant
Inflammation Hospitalization 9/1/2009 68 Male 176 lb 5/12/2010 United States
Primary
Concomitant
Fistula Hospitalization 5/1/2010 57 Male 193 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Fistula Hospitalization 5/1/2010 57 Male 193 lb 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/10/2009 59 Female 136 lb 6/25/2010 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/16/2010 74 Male 6/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 5/1/2010 57 Male 193 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 132 lb 7/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Renal Cancer Other Serious 64 Male 216 lb 7/16/2010 Physician France
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 4 Female 8/2/2010
Primary
Secondary
Thrombosis Other Serious 8/1/2009 65 Female 112 lb 8/13/2010 Consumer Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 9/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Femur Fracture Other Serious 3/31/2010 80 Female 9/24/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/7/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2004 61 Female 258 lb 10/25/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 27 Female 10/25/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 27 Female 10/25/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization Female 11/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 10/1/2010 61 Female 160 lb 11/6/2010 Consumer United States
Primary
Concomitant
Influenza 12/14/2009 12/15/2010 Consumer United States
Primary
Concomitant
Pelvic Fracture Other Serious Female 12/17/2010 Consumer United States
Primary
Concomitant
Appendicitis Hospitalization 12/7/2010 53 Female 132 lb 12/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 11/16/2010 58 Female 119 lb 1/11/2011 Physician Poland
Primary
Secondary
Concomitant
Appendicitis Hospitalization 12/7/2010 53 Female 132 lb 1/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious Female 1/17/2011 Consumer United States
Primary
Concomitant
Lip Pain 12/4/2009 72 Male 1/28/2011 Consumer United States
Primary
Concomitant
Pain 8/10/2010 44 Female 1/29/2011 Consumer United States
Primary
Concomitant
Pain 1/1/2010 61 Female 125 lb 1/29/2011 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2010 72 Female 180 lb 1/30/2011 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/1/2010 46 Female 1/30/2011 Consumer United States
Primary
Concomitant
Delirium Hospitalization Female 2/3/2011 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 17 Female 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 5/1/2010 57 Male 193 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Appendicitis Hospitalization 12/7/2010 53 Female 132 lb 2/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Other Serious 1/1/2008 69 Female 165 lb 2/22/2011 Consumer United States
Primary
Secondary
Concomitant
Death Other Serious 1/22/2011 76 Female 2/28/2011 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 65 Female 3/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Influenza Hospitalization 1/1/2007 47 Female 157 lb 3/16/2011 Consumer Brazil
Primary
Concomitant
Movement Disorder Other Serious 1/1/2008 69 Female 165 lb 3/22/2011 Physician United States
Primary
Secondary
Concomitant
Neck Pain Hospitalization 1/1/2010 65 Female 3/23/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2010 61 Female 160 lb 2/7/2011 Consumer United States
Primary
Concomitant
Anxiety Death Female 116 lb 4/20/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 11/28/2010 62 Female 160 lb 2/7/2011 Consumer United States
Primary
Concomitant
Osteoporosis Other Serious 1/1/2004 52 Female 132 lb 5/5/2011 Consumer Brazil
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization Female 116 lb 5/10/2011 Consumer United States
Primary
Concomitant
Inguinal Hernia Congenital Anomaly 28 Male 5/27/2011 Other Health Professional United States
Primary
Secondary
Urinary Incontinence Other Serious 1/1/2004 61 Female 258 lb 6/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Cognitive Disorder Hospitalization Female 116 lb 5/23/2011 Consumer United States
Primary
Concomitant
General Physical Health Deterioration 4/1/2011 Female 6/2/2011 Consumer United States
Primary
Concomitant
Ear Infection 11/28/2010 62 Female 160 lb 5/12/2011 Consumer United States
Primary
Concomitant
Clostridial Infection Hospitalization 12/1/2010 58 Male 200 lb 6/21/2011 Consumer United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious Female 230 lb 6/20/2011 Lawyer United States
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 17 Female 6/28/2011 Other Health Professional United States
Primary
Secondary
Pain In Extremity Other Serious 5/1/2011 64 Male 7/21/2011 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 10/1/2010 47 Female 188 lb 7/27/2011 Physician France
Primary
Concomitant
General Physical Health Deterioration Hospitalization 10/1/2010 47 Female 188 lb 7/28/2011 Physician France
Primary
Concomitant
Alopecia Other Serious 1/1/2010 38 Female 163 lb 8/29/2011 Consumer Brazil
Primary
Concomitant
Abdominal Pain Other Serious 1/1/2004 61 Female 258 lb 9/11/2011 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 7/28/2011 60 Female 172 lb 9/12/2011 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 5/25/2009 59 Male 220 lb 9/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 9/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Discomfort Other Serious Female 9/27/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious Female 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling Other Serious Female 10/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 7/14/2011 57 Female 10/27/2011 Physician United States
Primary
Secondary
Concomitant
Eye Infection 3/10/2011 52 246 lb 11/17/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 12/18/2010 73 Female 11/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 10/1/2011 53 Female 243 lb 11/21/2011 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 7/25/2011 60 Female 172 lb 11/30/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 7/25/2011 60 Female 172 lb 12/9/2011 Physician United States
Primary
Secondary
Concomitant
Headache 9/1/2009 35 Female 12/13/2011 Consumer United States
Primary
Concomitant
Nodular Regenerative Hyperplasia Other Serious 1/1/2007 Male 12/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 7/25/2011 60 Female 172 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 9/16/2011 61 Female 132 lb 12/22/2011 Consumer United States
Primary
Concomitant
Fall Other Serious 1/1/2007 47 Female 157 lb 12/22/2011 Consumer Brazil
Primary
Concomitant
Arthralgia Hospitalization 1/1/2007 47 Female 157 lb 12/27/2011 Consumer Brazil
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Life Threatening 12/1/2010 80 Female 12/28/2011 Other Health Professional France
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Other Serious Male 12/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/18/2011 46 Female 122 lb 11/3/2011 Physician United States
Primary
Concomitant

Drug Data