Ibuprofen combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Other Serious 47 Male 243 lb 1/3/2006 Physician Switzerland
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2005 44 Female 1/4/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Lymphoma Other Serious 10/1/2005 Female 143 lb 1/24/2006 Other Health Professional United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 1/10/2006 Female 280 lb 1/26/2006 Canada
Primary
Concomitant
Malignant Melanoma Other Serious 4/1/2005 Male 186 lb 1/26/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Male 229 lb 1/27/2006 Physician Brazil
Primary
Secondary
Concomitant
Skin Infection Hospitalization 3/27/2005 Male 1/31/2006 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious Male 2/1/2006 United Kingdom
Primary
Concomitant
Throat Tightness Other Serious 1/10/2006 Female 280 lb 2/3/2006 Canada
Primary
Concomitant
Juvenile Arthritis Other Serious 11/8/2005 4 Female 2/8/2006 United Kingdom
Primary
Concomitant
Lymphoma Other Serious 10/1/2005 Female 141 lb 2/15/2006 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 5/10/2005 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Ovarian Cyst Hospitalization 1/1/2005 Female 167 lb 2/28/2006 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 2/1/2005 1 Female 2/24/2006 United Kingdom
Primary
Concomitant
Syncope Other Serious Male 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Juvenile Arthritis Other Serious 11/8/2005 4 Female 2/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 5/24/2005 64 Male 2/22/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 4/1/2005 2 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Juvenile Arthritis Hospitalization 1/30/2006 15 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 14 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Pressure Decreased Death 2/13/2005 64 Male 223 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Hospitalization 4/1/2005 2 Female 3/2/2006 United Kingdom
Primary
Concomitant
Monarthritis Other Serious 9/13/2005 Female 99 lb 3/7/2006 Physician Germany
Primary
Concomitant
Lichenoid Keratosis Other Serious 1/1/2005 Male 3/14/2006 Other Health Professional Denmark
Primary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 3/22/2006 Consumer United States
Primary
Concomitant
Gastritis Other Serious 9/6/2005 Female 179 lb 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Female Other Serious 6/21/2005 53 Female 3/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 67 Female 110 lb 3/27/2006 Physician United States
Primary
Concomitant
Infection Hospitalization 1/1/2003 60 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Toe Deformity Hospitalization Female 110 lb 4/21/2006 Consumer Canada
Primary
Concomitant
Upper Respiratory Tract Infection Life Threatening 9/1/2001 30 Male 187 lb 4/24/2006 Physician United States
Primary
Concomitant
Platelet Production Decreased Hospitalization 4/4/2006 60 Male 169 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Sepsis Death 2/7/2006 59 Male 5/3/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/22/2006 55 Female 209 lb 2/1/2006 Physician United States
Primary
Concomitant
Skin Infection Hospitalization 3/27/2005 Male 5/26/2006 Physician United Kingdom
Primary
Concomitant
Erythema Multiforme Other Serious 3/1/2006 55 Female 5/26/2006 Physician Spain
Primary
Concomitant
Weight Decreased Hospitalization 1/15/2006 Female 132 lb 6/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 2/17/2006 Female 161 lb 6/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 6/6/2006 53 Male 6/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toe Deformity Hospitalization Female 110 lb 6/29/2006 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 3/20/2006 Female 184 lb 6/27/2006 Pharmacist United States
Primary
Concomitant
Malaise Hospitalization 1/1/2005 12 Female 6/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tonsillar Hypertrophy Hospitalization 12/1/2005 56 Male 143 lb 6/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Humerus Fracture Other Serious 12/14/2005 Male 223 lb 7/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 6/27/2005 Female 161 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 2/17/2006 Female 161 lb 7/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hysterectomy Hospitalization 2/16/2006 Female 7/12/2006 Physician United States
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Therapy Non-responder Life Threatening 5/24/2005 64 Male 7/11/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/10/2005 Male 7/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 8/19/2005 12 Female 7/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Emotional Disorder Of Childhood Other Serious 12/24/2002 Female 7/31/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 8/1/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Panic Disorder Other Serious 10/10/2005 9 Female 7/27/2006 United Kingdom
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 6/27/2005 Female 161 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/14/2005 Female 132 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 8/19/2005 12 Female 8/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pregnancy Other Serious 3/1/2005 Female 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Anorectal Neoplasm Other Serious 7/11/2005 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 7/13/2005 51 Female 8/7/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Oral Mucosal Blistering Other Serious 8/2/2006 43 Female 211 lb 8/15/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2006 Female 8/22/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Sensory Loss Other Serious 60 Male 8/14/2006 United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/21/2006 Male 8/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/5/2006 Male 229 lb 9/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Postoperative Infection Other Serious 1/6/2004 Male 9/26/2006 Physician United States
Primary
Concomitant
Tonsillar Hypertrophy Hospitalization 12/1/2005 56 Male 143 lb 9/27/2006 Physician France
Primary
Secondary
Concomitant
Synovial Cyst Other Serious 1/1/2005 Female 10/5/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 9/25/2006 47 Female 135 lb 10/6/2006 Consumer United States
Primary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
T-cell Lymphoma Other Serious 8/23/2003 Female 157 lb 10/16/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 10/19/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Rash Other Serious 6/30/2006 Female 131 lb 6/30/2006 United States
Primary
Concomitant
Pneumonia Other Serious 2/17/2006 Female 161 lb 11/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2006 Female 80 lb 11/7/2006 Consumer Argentina
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 11/7/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 11/20/2006 Physician Australia
Primary
Secondary
Concomitant
Diarrhoea Other Serious 9/30/2006 30 Female 11/22/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/13/2006 35 Female 205 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Synovitis Hospitalization 10/1/2005 Female 185 lb 12/1/2006 Physician
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 12/1/2006 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 10/1/2005 Female 108 lb 12/1/2006 Consumer United States
Primary
Concomitant
Skin Infection Hospitalization 3/25/2005 Male 12/4/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/5/2006 Male 229 lb 12/7/2006 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 74 Female 11/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 6/1/2006 Female 126 lb 12/11/2006 Physician United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 7/13/2006 Female 155 lb 12/13/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Congestion 7/15/2006 Female 257 lb 12/15/2006 Consumer United States
Primary
Secondary
Concomitant
Tinea Infection Other Serious 1/1/2004 Female 77 lb 12/19/2006 Physician United Kingdom
Primary
Concomitant
Mycosis Fungoides Other Serious 4/19/2006 Male 203 lb 12/22/2006 Physician United States
Primary
Concomitant
Urticaria Generalised 10/9/2006 52 Male 12/22/2006 Consumer United States
Primary
Concomitant
Synovial Fluid Analysis Hospitalization 8/26/2006 Male 12/22/2006 Other Health Professional Belgium
Primary
Concomitant
Vomiting Life Threatening 7/6/2006 Female 1/3/2007 Physician Australia
Primary
Secondary
Concomitant
Vasculitis Hospitalization 6/1/2004 Male 236 lb 1/10/2007 Physician Luxembourg
Primary
Concomitant
Oligodendroglioma Hospitalization 3/18/2005 66 Female 181 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 6/1/2004 Male 236 lb 1/18/2007 Physician Luxembourg
Primary
Concomitant
Swelling Hospitalization 7/1/2005 Male 134 lb 1/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumothorax Other Serious 6/30/2006 Female 133 lb 1/24/2007 Physician Canada
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2006 Male 260 lb 1/25/2007 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 7/6/2006 42 Female 1/26/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Diarrhoea Other Serious Female 203 lb 1/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Abscess Hospitalization 1/26/2007 56 Female 2/1/2007 Consumer Brazil
Primary
Concomitant
Femoral Neck Fracture Hospitalization 3/1/2004 Female 2/2/2007 Other Health Professional Germany
Primary
Concomitant
Urinary Retention Disability 14 Female 1/31/2007 Germany
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 1/26/2007 56 Female 2/9/2007 Consumer Brazil
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/6/2006 Female 212 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bowen's Disease Other Serious 11/2/2006 Female 179 lb 2/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 1/26/2007 56 Female 2/22/2007 Consumer Brazil
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 10/1/2006 Female 3/6/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 8/17/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 80 Female 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intentional Drug Misuse Other Serious 3/7/2007 Female 210 lb 3/20/2007 Consumer United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Other Serious 80 Female 3/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2006 Female 165 lb 3/22/2007 Physician Germany
Primary
Concomitant
B-cell Lymphoma Hospitalization 8/25/2006 Female 3/27/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 10/9/2006 Male 71 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Rhinitis Hospitalization 11/1/2006 Female 176 lb 3/28/2007 Consumer Germany
Primary
Concomitant
Arthropathy Hospitalization Female 200 lb 3/28/2007 Consumer Canada
Primary
Concomitant
Metastases To Liver Other Serious 2/1/2006 Female 112 lb 3/29/2007 Physician United States
Primary
Concomitant
Subcutaneous Abscess Hospitalization 1/26/2007 56 Female 4/13/2007 Consumer Brazil
Primary
Concomitant
Anaphylactic Reaction Life Threatening 6/24/2005 Male 204 lb 4/17/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2006 Female 165 lb 5/3/2007 Physician Germany
Primary
Concomitant
Tuberculosis Hospitalization 12/1/2006 Male 5/7/2007 Physician Finland
Primary
Concomitant
Weight Increased Other Serious 3/7/2007 Female 210 lb 5/8/2007 Physician United States
Primary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/14/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Wheezing Hospitalization 1/1/2006 Female 5/14/2007 Physician Norway
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/17/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 12/1/2006 Male 5/17/2007 Physician Finland
Primary
Concomitant
Rhinitis Hospitalization 11/1/2006 Female 176 lb 5/18/2007 Consumer Germany
Primary
Concomitant
Diarrhoea Hospitalization 5/5/2007 Male 168 lb 5/22/2007 Physician Netherlands
Primary
Concomitant
Oedema Other Serious 12/1/2005 Female 187 lb 5/24/2007 Consumer Canada
Primary
Concomitant
Thrombophlebitis Other Serious 5/9/2007 80 Female 5/25/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 9/13/2006 Female 205 lb 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/9/2007 80 Female 5/29/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 5/13/2007 Female 180 lb 6/15/2007 Consumer Canada
Primary
Concomitant
Breast Cancer Other Serious 6/21/2005 Female 6/26/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 6/26/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 7/1/2004 Female 6/28/2007 Other Health Professional Sweden
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2006 Female 110 lb 7/27/2007 Canada
Primary
Concomitant
Weight Decreased Other Serious 7/27/2005 Female 132 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 8/14/2005 Female 132 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 9/1/2006 Female 139 lb 8/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Function Test Decreased Other Serious 16 Female 8/6/2007 United Kingdom
Primary
Secondary
Liver Function Test Abnormal Other Serious 11/10/2005 22 Male 245 lb 8/24/2007 Physician Canada
Primary
Concomitant
Sepsis Other Serious 6/25/2007 Female 123 lb 8/24/2007 United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 7/1/2004 Female 8/27/2007 Other Health Professional Sweden
Primary
Concomitant

Drug Data