Captopril combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Other Serious 49 Female 1/19/2006 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 5/10/2005 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/24/2005 64 Male 2/22/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/24/2005 51 Female 3/14/2006 Brazil
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 5/1/2006 Physician Brazil
Primary
Concomitant
Thrombosis Death 6/12/2006 51 Female 164 lb 7/5/2006 Other Health Professional United States
Primary
Concomitant
Therapy Non-responder Life Threatening 5/24/2005 64 Male 7/11/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 5/10/2005 Male 7/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 8/1/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Hypertensive Crisis Hospitalization 3/1/2006 61 Female 8/1/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Malignant Anorectal Neoplasm Other Serious 7/11/2005 Female 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalitis Herpes Hospitalization 2/23/2006 Female 8/16/2006 Physician Brazil
Primary
Concomitant
Rectal Cancer Other Serious 7/13/2005 51 Female 8/7/2006 Other Health Professional Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 110 lb 8/24/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 10/19/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 9/25/2006 Female 117 lb 11/3/2006 Physician Colombia
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/24/2006 Male 163 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/1/2006 67 Female 11/7/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Thrombosis Death 6/12/2006 51 Female 164 lb 2/21/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 4/8/2007 59 Female 5/7/2007 Other Health Professional Mexico
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/16/2006 Female 123 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Injury Hospitalization 2/1/2005 Female 6/11/2007 Physician United States
Primary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Type Iii Immune Complex Mediated Reaction Other Serious 5/7/2007 1 Male 13 lb 7/19/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 8/6/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 3/1/2003 68 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 7/1/2007 Female 148 lb 9/28/2007 Brazil
Primary
Concomitant
Bone Marrow Toxicity Hospitalization 9/12/2007 66 Female 10/11/2007 Other Health Professional Mexico
Primary
Secondary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 10/26/2007 Brazil
Primary
Secondary
Concomitant
Endometrial Cancer Other Serious 6/28/2007 Female 11/2/2007 Physician Switzerland
Primary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 11/2/2007 Brazil
Primary
Secondary
Concomitant
Pneumonia Legionella Other Serious 11/8/2007 85 143 lb 11/21/2007 Physician Israel
Primary
Concomitant
Endometrial Cancer Other Serious 6/28/2007 Female 12/12/2007 Physician Switzerland
Primary
Concomitant
Accidental Exposure 9/20/2007 Female 150 lb 12/14/2007 Consumer United States
Primary
Concomitant
Rash Macular Other Serious 7/1/2007 Female 148 lb 12/18/2007 Brazil
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 1/3/2008 Female 181 lb 1/14/2008 Brazil
Primary
Concomitant
Anaemia Hospitalization 9/12/2007 66 Female 1/25/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 1/25/2008 Brazil
Primary
Secondary
Concomitant
Rash Papular Other Serious 52 Female 2/21/2008
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/20/2004 67 Male 2/22/2008 Physician Germany
Primary
Secondary
Concomitant
Surgery Hospitalization 9/27/2004 29 Male 2/26/2008 Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/1/2007 Female 2/28/2008 Consumer United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 3/9/2008 Female 3/19/2008 Brazil
Primary
Concomitant
Hypertensive Crisis 3/9/2008 Female 176 lb 3/27/2008 Brazil
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 187 lb 3/28/2008 Brazil
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 2/5/2008 32 Female 209 lb 5/8/2008 Physician Brazil
Primary
Concomitant
Oral Disorder Other Serious Female 141 lb 5/28/2008 Brazil
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2008 Female 7/8/2008 Brazil
Primary
Concomitant
Injection Site Pain 5/1/2008 Female 130 lb 9/12/2008 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 4/1/2007 Female 156 lb 9/13/2008 United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 8/11/2008 Female 196 lb 9/18/2008 United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Thermal Burn Hospitalization 6/22/2008 Female 209 lb 11/5/2008 United Kingdom
Primary
Concomitant
Yellow Skin Hospitalization 8/7/2008 Female 11/11/2008 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 6/1/2008 Female 11/18/2008 Brazil
Primary
Concomitant
Intestinal Obstruction Hospitalization 6/11/2007 Female 117 lb 11/20/2008 Brazil
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 187 lb 12/2/2008 Brazil
Primary
Concomitant
Wound Drainage Other Serious 3/16/2008 Male 280 lb 12/15/2008 Other Health Professional United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 10/1/2008 Female 115 lb 3/16/2009 Physician Puerto Rico
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 1/5/2009 1 Female 15 lb 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Urticaria 2/9/2009 Female 127 lb 4/6/2009 Consumer
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/5/2009 1 Female 15 lb 3/27/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 1 Female 15 lb 4/13/2009 Physician
Primary
Secondary
Concomitant
Death Death 75 Male 4/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Death 1/3/2009 75 Male 163 lb 5/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Disability 2/1/2009 Female 7/1/2009 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Disability 2/1/2009 Female 7/29/2009 Physician United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 75 Male 163 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Incorrect Dose Administered 9/20/2007 Female 150 lb 9/12/2009 Consumer United States
Primary
Concomitant
Swelling Other Serious 1/1/2007 Male 220 lb 9/17/2009 Brazil
Primary
Concomitant
Spinal Column Stenosis Hospitalization 3/15/2009 Female 9/22/2009 United Kingdom
Primary
Concomitant
Swelling Other Serious 1/1/2007 Male 220 lb 10/15/2009 Brazil
Primary
Concomitant
Injection Site Warmth Hospitalization 10/6/2009 Female 247 lb 10/19/2009 Brazil
Primary
Concomitant
Swelling Other Serious 1/1/2007 Male 220 lb 10/22/2009 Brazil
Primary
Concomitant
Pain Other Serious 9/11/2006 Male 183 lb 11/4/2009 Brazil
Primary
Concomitant
Pain Disability 58 Female 220 lb 11/6/2009 Brazil
Primary
Concomitant
Drug Interaction Other Serious 3/11/2004 22 Female 11/11/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2008 Female 150 lb 12/7/2009 Brazil
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 Female 123 lb 12/8/2009 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 176 lb 12/11/2009 Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 8/24/2009 Female 132 lb 12/11/2009 Brazil
Primary
Concomitant
Device Failure Other Serious 1/1/2008 Female 165 lb 12/18/2009 Brazil
Primary
Concomitant
Pyrexia Hospitalization 12/20/2009 76 Male 1/19/2010 Pharmacist Netherlands
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 10/5/2006 35 Female 1/25/2010
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2009 Female 220 lb 1/25/2010 Brazil
Primary
Secondary
Concomitant
Foot Deformity Other Serious Female 132 lb 1/27/2010 Brazil
Primary
Concomitant
Pyrexia Hospitalization 12/1/2009 76 Male 220 lb 2/8/2010 Pharmacist Netherlands
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/1/2009 76 Male 220 lb 2/11/2010 Pharmacist Netherlands
Primary
Secondary
Concomitant
Urticaria 2/9/2009 60 Female 128 lb 2/22/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2008 Female 150 lb 3/10/2010 Brazil
Primary
Concomitant
Peritonitis Hospitalization 1/30/2010 58 Female 4/19/2010 Physician Peru
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/24/2009 36 Female 132 lb 4/21/2010 Brazil
Primary
Concomitant
Foot Deformity Female 132 lb 4/21/2010 Brazil
Primary
Concomitant
Wound Other Serious 1/1/2009 34 Male 154 lb 6/2/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 53 Female 165 lb 6/4/2010 Consumer Brazil
Primary
Concomitant
Wound Hospitalization 1/1/2009 34 Male 154 lb 6/22/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 132 lb 7/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 3/24/2010 56 Female 205 lb 7/8/2010 Physician Lithuania
Primary
Concomitant
Cellulitis Hospitalization 6/19/2010 69 Male 166 lb 7/13/2010 Physician United States
Primary
Concomitant
Intestinal Perforation Other Serious 7/17/2010 61 Female 161 lb 7/29/2010 Physician Mexico
Primary
Secondary
Concomitant
Foot Deformity Female 132 lb 7/30/2010 Consumer Brazil
Primary
Concomitant
Intestinal Perforation Other Serious 7/17/2010 61 Female 161 lb 8/3/2010 Physician Mexico
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2007 44 Female 150 lb 8/6/2010 Consumer Brazil
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2010 59 Male 185 lb 8/12/2010 Consumer Brazil
Primary
Concomitant
Pain In Extremity Hospitalization 7/16/2010 46 Female 187 lb 8/13/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2006 49 Male 190 lb 8/19/2010 Consumer Brazil
Primary
Concomitant
Respiratory Distress Hospitalization 5/3/2010 2 Male 8/16/2010 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 7/16/2010 46 Female 187 lb 9/2/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 1/1/2005 59 Female 131 lb 9/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Hospitalization 1/1/2009 34 Male 154 lb 10/28/2010 Physician United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 3/24/2010 56 Female 205 lb 10/29/2010 Other Health Professional Lithuania
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 6/19/2010 69 Male 166 lb 11/5/2010 Physician United States
Primary
Concomitant
Thirst Other Serious 1/1/2010 46 Female 161 lb 11/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Arthropod Bite Hospitalization 70 Female 126 lb 12/10/2010 Physician Peru
Primary
Concomitant
Thirst Other Serious 1/1/2010 46 Female 161 lb 12/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Infected Bites Hospitalization 70 Female 126 lb 12/27/2010 Physician Peru
Primary
Concomitant
Thirst Other Serious 1/1/2009 45 Female 161 lb 1/14/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Cervix Carcinoma Death 11/24/2010 77 Female 152 lb 1/20/2011 Other Health Professional Spain
Primary
Concomitant
Hypersensitivity Other Serious 1/1/2010 46 Female 161 lb 1/21/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash 7/2/2010 37 Male 1/29/2011 Consumer United States
Primary
Concomitant
Monoplegia Other Serious 1/1/2006 49 Male 190 lb 2/28/2011 Consumer Brazil
Primary
Concomitant
Cellulitis Hospitalization 2/13/2011 61 Female 170 lb 3/8/2011 Physician Peru
Primary
Concomitant
Weight Decreased Hospitalization Female 160 lb 3/15/2011 Consumer United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 2/6/2011 61 Female 170 lb 3/31/2011 Physician Peru
Primary
Concomitant
Priapism Hospitalization 10/1/2010 69 152 lb 4/6/2011 Consumer Netherlands
Primary
Concomitant
Pain In Extremity Other Serious 11/1/2010 53 Female 161 lb 4/15/2011 Consumer Brazil
Primary
Concomitant
Depression Hospitalization 6/1/2010 59 Male 192 lb 4/18/2011 Consumer Brazil
Primary
Concomitant
Osteoporosis Other Serious 1/1/2004 52 Female 132 lb 5/5/2011 Consumer Brazil
Primary
Secondary
Concomitant
Memory Impairment Other Serious 1/1/2008 47 Female 5/10/2011 Consumer Brazil
Primary
Concomitant
Anaemia Hospitalization 5/7/2011 66 Female 5/16/2011 Other Health Professional Mexico
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 5/2/2011 80 Female 106 lb 5/17/2011 Physician Peru
Primary
Concomitant
Lobar Pneumonia Hospitalization 5/10/2011 66 Female 5/24/2011 Other Health Professional Mexico
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2010 69 152 lb 5/25/2011 Consumer Netherlands
Primary
Concomitant
Lobar Pneumonia Death 5/10/2011 66 Female 6/1/2011 Other Health Professional Mexico
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 4/11/2011 45 Male 254 lb 6/6/2011 Consumer Brazil
Primary
Concomitant
Vitamin D Abnormal Other Serious 1/1/2008 47 Female 6/7/2011 Consumer Brazil
Primary
Concomitant
Joint Effusion Other Serious 3/1/2010 74 Female 141 lb 6/8/2011 Consumer United Kingdom
Primary
Concomitant
Oesophageal Candidiasis Other Serious 5/2/2011 80 Female 106 lb 6/10/2011 Physician Peru
Primary
Concomitant
Hypersensitivity Hospitalization 10/1/2010 69 152 lb 6/28/2011 Consumer Netherlands
Primary
Concomitant
Joint Effusion Other Serious 3/1/2010 74 Female 141 lb 6/29/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/23/2011 22 Male 132 lb 7/7/2011 Pharmacist Brazil
Primary
Concomitant
Arthralgia Other Serious 3/1/2010 74 Female 141 lb 8/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 7/1/2011 50 Female 8/11/2011 Consumer Germany
Primary
Concomitant
Dyspnoea Other Serious 3/23/2011 22 Male 132 lb 9/23/2011 Pharmacist Brazil
Primary
Concomitant

Drug Data