Methotrexate combined with Oncovin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/1/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/8/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/27/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 3/2/2006 Physician Japan
Primary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 3/9/2006 Physician Portugal
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/28/2004 75 Male 3/6/2006 Physician France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/1/2005 76 Male 3/18/2006 Pharmacist Japan
Primary
Concomitant
Treatment Related Secondary Malignancy Death 3/1/2005 42 Female 3/28/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/3/2004 30 Female 99 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/5/2006 Consumer United States
Primary
Secondary
Concomitant
Petechiae Hospitalization 6/8/2002 63 Female 5/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/8/2002 63 Female 5/5/2006 Other Health Professional France
Primary
Secondary
Prostration Hospitalization 12/1/2005 Male 168 lb 5/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Chronic Eosinophilic Leukaemia Hospitalization 12/1/2000 43 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 1/1/2001 56 Male 7/25/2006 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 37 Female 7/25/2006 Physician Japan
Primary
Secondary
Weight Decreased Hospitalization 12/30/2004 75 Male 8/2/2006 Physician France
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/9/2004 68 Female 8/11/2006 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 51 Male 9/21/2006 France
Primary
Secondary
Concomitant
Petechiae Hospitalization 6/8/2002 63 Female 12/5/2006 Other Health Professional France
Primary
Secondary
Mucosal Inflammation Hospitalization 11/17/2006 63 Female 12/11/2006 Consumer United States
Primary
Secondary
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/10/2006 75 Male 1/30/2007 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 6/24/2004 31 Female 2/21/2007 Consumer Japan
Primary
Secondary
Interstitial Lung Disease Life Threatening 6/24/2004 31 Female 3/5/2007 Consumer Japan
Primary
Secondary
Toxic Skin Eruption Other Serious 46 Male 3/13/2007 United States
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 1/23/2006 64 Male 3/23/2007 Consumer Japan
Primary
Secondary
Streptococcal Bacteraemia Death 12 Female 4/2/2007 Physician Japan
Primary
Concomitant
Venous Thrombosis Limb Other Serious 31 Female 4/2/2007 Physician Japan
Primary
Secondary
Pyrexia Other Serious 12/23/2006 Female 163 lb 4/4/2007 Physician Bahrain
Primary
Concomitant
Venous Thrombosis Limb Other Serious 31 Female 4/5/2007 Physician Japan
Primary
Secondary
Streptococcal Bacteraemia Death 12 Female 4/6/2007 Physician Japan
Primary
Concomitant
Venous Thrombosis Limb Other Serious 31 Female 4/24/2007 Physician Japan
Primary
Secondary
Streptococcal Bacteraemia Death 12 Female 5/7/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/11/2006 10 Female 68 lb 5/16/2007 Consumer United States
Primary
Secondary
Weight Decreased Hospitalization 1/1/2006 Female 110 lb 6/8/2007 Physician Finland
Primary
Secondary
Methaemoglobinaemia Life Threatening 4/26/2007 Female 141 lb 6/13/2007 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 110 lb 6/14/2007 Physician Finland
Primary
Secondary
Azoospermia Disability 1/15/2002 21 Male 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Pleural Fibrosis Disability 2/1/1994 29 Male 79 lb 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Azoospermia Disability 1/15/2002 21 Male 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 7/9/2007 United Kingdom
Primary
Concomitant
Cachexia Death 57 8/3/2007 Netherlands
Primary
Secondary
Concomitant
Cachexia Death 60 8/3/2007 Netherlands
Primary
Secondary
Concomitant
Hepatitis B Death 3/1/2006 54 Male 9/11/2007 Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 2/1/2006 54 Male 9/18/2007 Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 2/1/2006 54 Male 10/2/2007 Japan
Primary
Secondary
Concomitant
Somnolence Life Threatening 7/1/2007 9 Female 9/27/2007 Physician France
Primary
Secondary
Concomitant
Pneumonia Death 1/13/2007 28 Female 10/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/19/2007 50 Female 10/31/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 28 Female 11/5/2007 Consumer United States
Primary
Secondary
Sepsis Other Serious 70 Female 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Somnolence Life Threatening 7/1/2007 9 Female 11/26/2007 Physician France
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 28 Female 12/10/2007 Consumer Japan
Primary
Secondary
Skin Ulcer Other Serious 3/28/2007 29 Male 163 lb 12/14/2007 Physician Japan
Primary
Concomitant
Multi-organ Failure Death 1/19/2008 71 Female 148 lb 3/12/2008 Physician France
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/5/2008 58 Female 5/28/2008 Consumer United States
Primary
Secondary
Gastric Haemorrhage Other Serious 8/30/2006 63 Male 6/10/2008 Consumer United States
Primary
Secondary
Gastric Perforation Other Serious 11/23/2005 46 Male 6/10/2008 Consumer United States
Primary
Secondary
Febrile Bone Marrow Aplasia Other Serious 6/18/2005 53 Male 6/10/2008 Consumer United States
Primary
Secondary
Peroneal Muscular Atrophy Other Serious 4/6/2006 23 Male 6/10/2008 Consumer United States
Primary
Secondary
Septic Shock Other Serious 7/1/2005 65 Male 6/10/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/18/2007 69 Male 6/10/2008 Consumer United States
Primary
Secondary
Mucosal Inflammation Other Serious 11/1/2006 34 Female 6/10/2008 Consumer United States
Primary
Secondary
Skin Toxicity Other Serious 2/3/2005 18 Male 6/11/2008 Consumer United States
Primary
Secondary
Tachyphrenia Other Serious 7/23/2005 55 Male 6/11/2008 Consumer United States
Primary
Secondary
Renal Failure Death 12/1/2006 62 Male 6/11/2008 Consumer United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 163 lb 6/20/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious Female 6/26/2008 Other Health Professional France
Primary
Secondary
Pancreatitis Necrotising Hospitalization 5/30/2008 10 Male 6/27/2008 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 8/7/2008 44 Male 148 lb 8/21/2008 Belgium
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/5/2008 58 Female 9/10/2008 Consumer United States
Primary
Secondary
Wrong Drug Administered Life Threatening 9/19/2008 71 Male 9/23/2008 Physician Italy
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2007 20 Male 10/24/2008 Physician Japan
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2007 20 Male 10/24/2008 Physician Japan
Primary
Secondary
Somnolence Life Threatening 9/19/2008 71 Male 10/29/2008 Physician Italy
Primary
Concomitant
Burkitt's Lymphoma Hospitalization 1/1/2008 66 Male 11/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 7/10/2008 Female 99 lb 11/6/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration Life Threatening 9/19/2008 71 Male 11/6/2008 Physician Italy
Primary
Concomitant
Burkitt's Lymphoma Other Serious 1/1/2008 68 Male 11/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 1 Male 22 lb 11/12/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 1 Male 22 lb 11/17/2008 Physician Japan
Primary
Concomitant
Somnolence Life Threatening 9/19/2008 71 Male 11/24/2008 Physician Italy
Primary
Concomitant
Wrong Drug Administered Life Threatening 9/19/2008 71 Male 12/4/2008 Physician Italy
Primary
Concomitant
Wrong Drug Administered Life Threatening 9/18/2008 71 Male 12/19/2008 Physician Italy
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/8/2008 Male 12/30/2008 Consumer United Kingdom
Primary
Secondary
Wrong Drug Administered Life Threatening 9/18/2008 71 Male 12/22/2008 Physician Italy
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 23 Female 1/5/2009 Physician United States
Primary
Concomitant
Stomatitis Other Serious 9/2/2008 Male 2/9/2009 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/18/2009 68 Male 2/12/2009 Physician France
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 50 Male 2/11/2009 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Confusional State Hospitalization 16 Male 2/23/2009 Other Health Professional Japan
Primary
Secondary
Confusional State Hospitalization 16 Male 3/6/2009 Other Health Professional Japan
Primary
Secondary
Stomatitis Other Serious 9/15/2008 Male 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2008 19 Male 110 lb 3/20/2009 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/18/2009 68 Male 3/26/2009 Physician France
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 9/1/2006 50 Male 4/1/2009
Primary
Secondary
Thirst Other Serious 12/25/2007 49 Female 123 lb 4/3/2009 Physician Japan
Primary
Concomitant
Lung Disorder Hospitalization 12/23/2008 4/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 12/23/2008 62 Male 4/16/2009 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 9/1/2007 63 Male 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/19/2009 Male 6/4/2009 Physician United Kingdom
Primary
Secondary
Haemolytic Anaemia Hospitalization 5/15/2009 27 6/9/2009 Pharmacist Switzerland
Primary
Concomitant
Bone Marrow Transplant Other Serious 3/1/2009 37 Male 99 lb 6/17/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 6/12/2009 70 Female 6/25/2009 Physician France
Primary
Secondary
Thymus Enlargement Other Serious 16 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Other Serious 7 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Staphylococcal Sepsis Hospitalization 3/23/2008 Male 7/10/2009 Consumer United Kingdom
Primary
Secondary
Leukocytosis Other Serious 5/8/2009 Male 179 lb 7/22/2009 Physician Switzerland
Primary
Secondary
Respiratory Failure Other Serious 8/1/1997 31 Male 8/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/1/1997 31 Male 8/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/14/2009 62 Male 8/17/2009 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2007 63 Male 8/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 53 9/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death Female 9/24/2009 Other Health Professional South Africa
Primary
Secondary
Toxic Epidermal Necrolysis Death 62 Female 11/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/14/2009 62 Male 11/20/2009 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 8/1/2009 53 Male 11/26/2009 Physician France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 62 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 47 Male 1/7/2010 Other Health Professional France
Primary
Concomitant
Muscular Weakness Life Threatening 84 Male 1/13/2010 Physician Japan
Primary
Concomitant
Aplasia Hospitalization 8/1/2008 Female 1/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Aplasia Hospitalization 8/1/2009 31 Female 1/22/2010 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 8/1/2008 Female 1/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2009 64 Female 123 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/3/2010 Female 90 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Interacting
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Aplasia Hospitalization 8/1/2008 31 Female 3/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 3/19/2010 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 17 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 1/3/2010 61 Female 90 lb 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Interacting
Pseudomembranous Colitis Other Serious 2/13/2010 46 Female 93 lb 6/1/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data