Methotrexate combined with Valtrex

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transplant Failure Hospitalization 11/21/2005 Male 176 lb 2/1/2006 Physician Germany
Primary
Concomitant
Drug Ineffective Female 2/15/2006 Consumer United States
Primary
Concomitant
Rash 3/29/2005 50 Female 239 lb 2/15/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Required Intervention 6/20/2005 18 Female 4/5/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 54 Male 4/5/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 4/18/2006 Physician Germany
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2002 65 Male 315 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Visual Acuity Reduced Required Intervention 6/20/2005 18 Female 4/17/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/5/2006 Physician Germany
Primary
Concomitant
Respiratory Failure Death 8/3/2005 43 Male 4/28/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Death 2/26/2006 Female 101 lb 5/8/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/8/2006 Physician Germany
Primary
Concomitant
Visual Field Defect Other Serious 2/1/2002 65 Male 315 lb 5/11/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/20/2006 70 Female 117 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Death 2/26/2006 Female 101 lb 5/23/2006 Physician Germany
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Death 2/26/2006 Female 101 lb 6/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 6/7/2006 Physician Germany
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Life Threatening 8/3/2005 43 Male 6/8/2006 Physician Japan
Primary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/3/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 8/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 8/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Thyroiditis Hospitalization 1/1/2006 Female 210 lb 9/1/2006 Other Health Professional United States
Primary
Concomitant
Fatigue 7/17/2006 62 Female 201 lb 10/2/2006 Consumer United States
Primary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Unclassifiable Death Female 12/8/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Fatigue 7/17/2006 62 Female 201 lb 12/22/2006 Physician United States
Primary
Concomitant
Meningitis Aseptic Other Serious 3/10/2007 59 Female 4/9/2007 Physician Switzerland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/11/2006 Male 198 lb 4/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2007 Female 125 lb 8/30/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 6/30/2007 51 Female 108 lb 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased 8/26/2005 54 Female 12/15/2006 Physician United States
Primary
Concomitant
Paraesthesia Hospitalization 8/6/2007 Female 10/31/2007 Physician United States
Primary
Concomitant
Osteopenia Other Serious 1/1/2002 Female 116 lb 12/6/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 60 Female 11/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 10/10/2007 50 Female 168 lb 1/8/2008 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Stress Urinary Incontinence Other Serious 8/6/2007 Female 1/31/2008 Physician United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 10/10/2007 50 Female 168 lb 2/7/2008 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Sweat Discolouration 9/1/2007 36 Female 237 lb 2/29/2008 Consumer United States
Primary
Concomitant
Skin Injury Hospitalization 3/6/2008 49 Male 277 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Disability 78 Female 159 lb 4/7/2008 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 6/13/2006 74 Male 198 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/2/2008 United States
Primary
Secondary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/9/2008 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 5/1/1999 Female 5/28/2008 Physician United States
Primary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms 5/1/2008 58 Female 240 lb 6/30/2008 Other Health Professional United States
Primary
Concomitant
Stomatitis Hospitalization 6/3/2008 27 Male 88 lb 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 11/12/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/31/2008 54 Male 164 lb 8/26/2008 Physician United States
Primary
Secondary
Concomitant
Systemic Mycosis Hospitalization 6/3/2008 Female 175 lb 9/16/2008 Consumer United States
Primary
Concomitant
Muscle Spasms 5/15/2008 58 Female 240 lb 9/25/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 3/31/2008 54 Male 164 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 5/20/2008 Female 208 lb 10/23/2008 Physician United States
Primary
Concomitant
Herpes Zoster Ophthalmic Other Serious 5/20/2008 Female 208 lb 11/10/2008 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Ophthalmic Other Serious 5/20/2008 Female 208 lb 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Nasopharyngitis 12/12/2007 Female 112 lb 11/17/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 2/28/2005 Female 167 lb 12/5/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Pain 10/24/2007 Female 240 lb 12/15/2008 Physician United States
Primary
Concomitant
Sinusitis 12/4/2007 Female 112 lb 12/18/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 2/28/2005 Female 167 lb 12/23/2008 Physician United States
Primary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 10/6/2004 Male 143 lb 12/23/2008 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 10/6/2004 Male 143 lb 1/16/2009 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Female 2/24/2009 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 11/12/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/7/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 5/4/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/20/2009 Female 170 lb 5/19/2009 Canada
Primary
Secondary
Concomitant
Melanocytic Naevus Other Serious 4/29/2009 Female 5/19/2009 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 6/22/2009 Female 8/3/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 8/11/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Herpes Zoster Other Serious Female 197 lb 8/27/2009 Consumer United States
Primary
Concomitant
Spinal Disorder Other Serious 12/1/2008 Female 9/2/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2008 Male 175 lb 9/4/2009 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 6/22/2009 Female 93 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 3/2/2008 69 Female 9/8/2009 United States
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Injection Site Pain 6/17/2009 Female 125 lb 9/19/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 9/1/2008 Female 180 lb 9/19/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
Spinal Disorder Other Serious 6/1/2008 Female 192 lb 11/19/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 9/1/2009 56 Male 243 lb 12/1/2009 Consumer United States
Primary
Secondary
Concomitant
Genital Herpes Hospitalization 9/14/2005 38 Female 178 lb 11/9/2009 Lawyer United States
Primary
Concomitant
Weight Decreased 11/1/2009 Female 119 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 9/15/2008 62 Female 134 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred 2/28/2009 54 Female 2/24/2010 Consumer United States
Primary
Concomitant
Impaired Healing Other Serious 1/1/2010 52 Female 4/29/2010 Other Health Professional Canada
Primary
Concomitant
Pneumonia Hospitalization 11/5/2009 46 Male 183 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/22/2009 45 Female 196 lb 5/19/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 6/4/2010 Physician United States
Primary
Concomitant
Postoperative Wound Infection Other Serious 3/22/2010 52 Female 6/15/2010 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 144 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/1/2009 74 Male 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 144 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/9/2010 40 Female 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/1/2008 60 Female 185 lb 8/6/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 8/17/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 1/1/2008 46 Female 350 lb 8/29/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Other Serious 2/1/2010 45 Female 150 lb 9/10/2010 Physician United States
Primary
Concomitant
Vertigo Other Serious 2/1/2010 45 Female 150 lb 9/13/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Labile Hypertension Other Serious 1/1/2007 62 Female 250 lb 9/17/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 9/21/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 9/22/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 9/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 10/13/2010 Other Health Professional
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 141 lb 10/14/2010 Other Health Professional
Primary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vocal Cord Disorder 53 Female 11/19/2010 Consumer United States
Primary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 11/1/2010 44 Female 180 lb 12/13/2010 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 9/18/2010 5 Female 53 lb 12/21/2010 Physician Japan
Primary
Concomitant
Weight Decreased 5/1/2010 20 Female 116 lb 11/6/2010 United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/8/2009 15 Male 157 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 121 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Glossitis Hospitalization 9/13/2010 58 Male 121 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/14/2005 38 Female 178 lb 11/4/2010 Lawyer United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 12/1/2010 59 Female 129 lb 1/27/2011 United States
Primary
Concomitant
Pain Female 160 lb 1/29/2011 Other Health Professional United States
Primary
Concomitant

Drug Data