Chloroquine Phosphate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Knee Arthroplasty Hospitalization 7/26/2004 Male 298 lb 2/6/2006 Germany
Primary
Concomitant
Synovectomy Hospitalization 3/23/2006 Male 168 lb 5/24/2006 Physician Germany
Primary
Concomitant
Ultrasound Antenatal Screen Abnormal Other Serious 4/3/2006 32 Female 5/30/2006 Physician Mexico
Primary
Secondary
Concomitant
Wound Other Serious 1/16/2006 Female 6/2/2006 Physician Brazil
Primary
Concomitant
Nervous System Disorder Death 38 Female 6/9/2006 France
Primary
Secondary
Trigeminal Nerve Disorder Death 1/1/2003 38 Female 6/8/2006 Physician France
Primary
Secondary
Concomitant
Trigeminal Nerve Disorder Death 1/1/2003 38 Female 6/23/2006 Physician France
Primary
Secondary
Concomitant
Pruritus Other Serious 50 Female 7/19/2006 Physician Brazil
Primary
Concomitant
B-cell Lymphoma Stage Ii Other Serious 4/13/2006 68 Male 132 lb 7/31/2006 Other Health Professional Germany
Primary
Concomitant
Pruritus Other Serious 50 Female 9/1/2006 Physician Brazil
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 7/26/2004 Male 298 lb 2/8/2007 Physician Germany
Primary
Secondary
Concomitant
Skin Necrosis Other Serious Female 196 lb 10/25/2007 Brazil
Primary
Concomitant
Skin Necrosis Other Serious Female 196 lb 11/1/2007 Brazil
Primary
Concomitant
Weight Increased Hospitalization 1/1/2007 Female 123 lb 12/13/2007 Physician Brazil
Primary
Concomitant
Pregnancy On Oral Contraceptive Other Serious 28 Female 11/12/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/31/2007 Female 148 lb 1/25/2008 Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2003 82 Female 1/29/2008 Physician Sweden
Primary
Concomitant
Weight Increased Hospitalization 1/1/2007 Female 123 lb 2/13/2008 Physician Brazil
Primary
Concomitant
Upper Respiratory Tract Congestion Hospitalization 1/28/2008 Female 121 lb 2/22/2008 Germany
Primary
Concomitant
Drug Exposure During Pregnancy 11/1/2007 37 Female 3/7/2008 Physician El Salvador
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 3/12/2008 Other Health Professional Brazil
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/9/2008 Female 121 lb 3/13/2008 Germany
Primary
Secondary
Concomitant
Pain Hospitalization Female 198 lb 3/27/2008 Brazil
Primary
Concomitant
Pancreatitis Hospitalization 5/13/2008 Female 106 lb 6/9/2008 Physician Colombia
Primary
Secondary
Concomitant
Tuberculous Tenosynovitis Hospitalization 48 Female 6/17/2008 Germany
Primary
Secondary
Heart Rate Irregular Hospitalization 5/1/2008 Female 7/10/2008 Belgium
Primary
Concomitant
Tuberculosis Other Serious 63 Female 7/31/2008
Primary
Secondary
Concomitant
Premature Labour Other Serious 1/22/2008 Female 8/18/2008 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy 11/1/2007 37 Female 9/10/2008 Physician El Salvador
Primary
Secondary
Gait Disturbance Hospitalization Female 9/23/2008 Brazil
Primary
Concomitant
Respiratory Arrest Hospitalization 7/1/2008 Female 9/24/2008 Brazil
Primary
Concomitant
Pyrexia Hospitalization 9/24/2008 64 Male 10/10/2008 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2006 Female 10/14/2008 Brazil
Primary
Concomitant
Hip Arthroplasty Hospitalization 10/11/2008 Female 11/18/2008 Brazil
Primary
Concomitant
Vomiting Hospitalization 11/20/2008 Female 141 lb 12/5/2008 Mexico
Primary
Concomitant
Pain Hospitalization Female 12/8/2008 Brazil
Primary
Concomitant
Pain In Extremity Other Serious Female 12/19/2008 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 11/20/2008 Male 141 lb 12/26/2008 Mexico
Primary
Concomitant
Pain Hospitalization 8/6/2008 Female 12/26/2008 Brazil
Primary
Concomitant
Musculoskeletal Pain Hospitalization Female 1/26/2009 Brazil
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 70 Male 1/22/2009 Physician United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization 1/1/2007 Female 2/6/2009 Brazil
Primary
Concomitant
Femur Fracture Other Serious 1/1/2008 Female 2/11/2009 Brazil
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 2/22/2008 Male 2/17/2009 Other Health Professional Spain
Primary
Concomitant
Anaemia Hospitalization Female 3/9/2009 Brazil
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 2/20/2009 Male 3/10/2009 Physician United Kingdom
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 2/22/2008 Male 3/27/2009 Other Health Professional Spain
Primary
Concomitant
Vasculitis Other Serious 40 Female 3/31/2009 Physician United States
Primary
Concomitant
Synovial Cyst Other Serious Female 4/6/2009 Brazil
Primary
Concomitant
Tuberculosis Death 2/20/2009 Male 4/7/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2009 Male 168 lb 4/27/2009 Physician South Africa
Primary
Secondary
Concomitant
Synovial Cyst Other Serious Female 5/5/2009 Brazil
Primary
Concomitant
Pneumonia Life Threatening 1/18/2009 Female 5/11/2009 Physician Hungary
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 71 Female 5/15/2009
Primary
Secondary
Concomitant
Pneumonia Life Threatening 1/18/2009 Female 132 lb 5/19/2009 Physician Hungary
Primary
Secondary
Concomitant
Synovial Cyst Other Serious Female 137 lb 5/28/2009 Brazil
Primary
Concomitant
Pneumonia Life Threatening 1/18/2009 Female 132 lb 5/28/2009 Physician Hungary
Primary
Secondary
Concomitant
Dermatitis Psoriasiform Hospitalization 2/25/2009 66 Female 6/2/2009 Other Health Professional Sweden
Primary
Concomitant
Synovial Cyst Other Serious Female 137 lb 6/5/2009 Brazil
Primary
Concomitant
Vomiting Death 7/18/2009 57 Male 128 lb 7/31/2009 Physician Colombia
Primary
Concomitant
Tooth Loss Other Serious 1/1/2005 Female 132 lb 12/3/2009 Brazil
Primary
Concomitant
Weight Decreased Other Serious Female 115 lb 12/11/2009 Consumer Brazil
Primary
Concomitant
Wound Secretion Hospitalization 11/23/2009 Female 212 lb 12/17/2009 Brazil
Primary
Concomitant
Joint Dislocation Other Serious 7/31/2009 Female 121 lb 1/15/2010 Brazil
Primary
Concomitant
Pyrexia Hospitalization 8/1/2009 Male 154 lb 1/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 11/23/2009 Female 212 lb 1/20/2010 Brazil
Primary
Concomitant
Pyrexia Hospitalization 8/1/2009 Male 154 lb 1/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 1/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/19/2000 Female 145 lb 1/28/2010 United States
Primary
Secondary
Concomitant
Subdural Haematoma Death 4/25/2009 87 Female 123 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Life Threatening 10/16/2009 Female 150 lb 2/1/2010 Physician Brazil
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Leukocytosis Other Serious 1/1/2009 Male 220 lb 2/4/2010 Germany
Primary
Concomitant
Sepsis Hospitalization 8/1/2009 Male 154 lb 2/8/2010 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2009 Male 154 lb 2/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 7/1/2009 Male 128 lb 2/12/2010 Physician Colombia
Primary
Concomitant
Spinal Decompression Other Serious 8/1/2009 Female 154 lb 2/12/2010 Brazil
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 8/17/2009 Female 121 lb 2/12/2010 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 9/1/2009 Female 139 lb 2/26/2010 Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2009 Female 84 lb 3/11/2010 Brazil
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 8/17/2009 Female 121 lb 3/16/2010 Consumer Brazil
Primary
Concomitant
Leukocytosis Other Serious 1/1/2009 Male 220 lb 3/19/2010 Germany
Primary
Concomitant
Lung Neoplasm Other Serious 10/16/2009 Female 150 lb 3/19/2010 Physician Brazil
Primary
Concomitant
Wound Secretion Other Serious 11/23/2009 Female 214 lb 3/26/2010 Brazil
Primary
Concomitant
Spinal Decompression Other Serious 8/1/2009 50 Female 154 lb 4/23/2010 Brazil
Primary
Concomitant
Chest Pain Hospitalization 4/5/2010 53 Female 4/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 4/19/2010 34 Female 174 lb 5/4/2010 Consumer United Kingdom
Primary
Concomitant
Spinal Decompression Other Serious 12/1/2009 50 Female 154 lb 5/5/2010 Brazil
Primary
Concomitant
Weight Increased Other Serious 9/1/2009 44 Female 139 lb 5/13/2010 Brazil
Primary
Secondary
Concomitant
Pain Other Serious Female 146 lb 5/13/2010 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/8/2010 59 Female 165 lb 5/15/2010 Physician Brazil
Primary
Concomitant
Lung Neoplasm Life Threatening 10/16/2009 64 Female 150 lb 5/18/2010 Physician Brazil
Primary
Concomitant
Weight Decreased Other Serious 1/19/2000 54 Female 145 lb 5/20/2010 United States
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 60 Female 5/21/2010 Physician France
Primary
Concomitant
Lung Neoplasm Life Threatening 10/16/2009 64 Female 150 lb 5/28/2010 Physician Brazil
Primary
Concomitant
Weight Decreased Other Serious 6/15/2009 50 Female 165 lb 6/2/2010 Consumer Brazil
Primary
Concomitant
Weight Decreased Other Serious 6/15/2009 50 Female 165 lb 6/3/2010 Consumer Brazil
Primary
Concomitant
Benign Hydatidiform Mole Other Serious Female 6/7/2010 Physician Brazil
Primary
Concomitant
Skin Lesion Other Serious 39 Male 6/8/2010 Other Health Professional Hungary
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 6/9/2010 Physician Brazil
Primary
Concomitant
Leukocytosis Other Serious 1/1/2009 57 Male 220 lb 6/10/2010 Physician Germany
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 137 lb 6/15/2010 Physician Brazil
Primary
Concomitant
Lung Neoplasm Life Threatening 10/16/2009 64 Female 150 lb 6/16/2010 Physician Brazil
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2010 41 Female 168 lb 6/16/2010 Consumer Brazil
Primary
Concomitant
Lung Neoplasm Life Threatening 10/16/2009 64 Female 150 lb 6/18/2010 Physician Brazil
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 137 lb 6/23/2010 Physician Brazil
Primary
Concomitant
Leukocytosis Other Serious 1/1/2009 57 Male 220 lb 6/24/2010 Physician Germany
Primary
Concomitant
Lung Adenocarcinoma Life Threatening 10/16/2009 64 Female 150 lb 7/6/2010 Physician Brazil
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 137 lb 7/8/2010 Physician Brazil
Primary
Concomitant
Pain In Extremity Other Serious Female 146 lb 7/9/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 132 lb 7/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Wound Hospitalization 4/1/2009 47 Female 157 lb 7/12/2010 Consumer Brazil
Primary
Concomitant
Pain In Extremity Other Serious Female 146 lb 7/16/2010 Consumer United Kingdom
Primary
Concomitant
Colon Adenoma Hospitalization 4/8/2010 59 Female 165 lb 7/28/2010 Physician Brazil
Primary
Concomitant
Wound Secretion Other Serious 11/23/2009 56 Female 214 lb 7/29/2010 Consumer Brazil
Primary
Concomitant
Pulmonary Mass Hospitalization 6/3/2010 55 Female 8/3/2010 Physician Thailand
Primary
Secondary
Concomitant
Inflammation Other Serious 1/1/2010 70 Male 176 lb 8/5/2010 Consumer Brazil
Primary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 8/5/2010 Physician Canada
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 12/2/2009 57 Female 8/9/2010 Other Health Professional Sweden
Primary
Concomitant
Pneumonia Hospitalization 7/29/2010 55 Female 8/17/2010 Physician Thailand
Primary
Secondary
Concomitant
Vomiting Other Serious 8/4/2010 35 Female 8/31/2010 Consumer Colombia
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 54 Female 146 lb 9/1/2010 Consumer Brazil
Primary
Secondary
Concomitant
Septic Shock Death 12/1/2008 66 Female 176 lb 9/1/2010 Consumer United Kingdom
Primary
Concomitant
Osteomyelitis Other Serious 7/27/2010 58 Female 150 lb 10/8/2010 Physician Canada
Primary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/14/2010 Consumer Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/15/2010 Consumer Brazil
Primary
Concomitant
Immune System Disorder Other Serious Female 134 lb 10/19/2010 Consumer Brazil
Primary
Concomitant
Vertigo Hospitalization 4/19/2010 34 Female 174 lb 10/19/2010 Consumer United Kingdom
Primary
Concomitant
Immunodeficiency Other Serious Female 134 lb 10/20/2010 Consumer Brazil
Primary
Concomitant
Urinary Bladder Rupture Other Serious 8/16/2009 60 Male 194 lb 10/21/2010 Consumer Brazil
Primary
Concomitant
Vomiting Disability 5/4/2010 48 Female 132 lb 10/26/2010 Consumer United Kingdom
Primary
Concomitant
Rash Hospitalization 9/1/2010 55 Male 176 lb 11/3/2010 Physician South Africa
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 46 Female 159 lb 11/12/2010 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious 3/1/2010 60 Female 141 lb 11/17/2010 Physician United Kingdom
Primary
Concomitant
Immunodeficiency Other Serious Female 134 lb 11/17/2010 Consumer Brazil
Primary
Concomitant
Venous Thrombosis Hospitalization 1/1/2010 11/17/2010 Physician Colombia
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 1/1/2010 11/17/2010 Physician Colombia
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 46 Female 159 lb 11/23/2010 Physician Brazil
Primary
Concomitant
Tachypnoea Other Serious 44 Female 12/9/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 146 lb 12/10/2010 Consumer United Kingdom
Primary
Concomitant
Hypotonia Other Serious 12/14/2010 Consumer Brazil
Primary
Concomitant
Varicose Vein Other Serious 12/21/2010 Consumer Brazil
Primary
Concomitant
Diarrhoea Other Serious 3/25/2011 67 Male 183 lb 4/19/2011 Other Health Professional Canada
Primary
Concomitant
Inflammation Other Serious 8/1/2008 26 Male 187 lb 10/13/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Synovitis Other Serious 11/1/2001 Female 12/9/2011 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 57 Female 168 lb 12/14/2011 Physician Lebanon
Primary
Concomitant
Pain In Extremity 3/1/2011 81 1/27/2012 Consumer United States
Primary
Concomitant
Localised Infection Hospitalization 6/25/2009 45 Female 176 lb 2/6/2012 Consumer Brazil
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 2/14/2012 30 Female 90 lb 3/2/2012 Physician Poland
Primary
Concomitant

Drug Data