Darvocet-N 100 combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Tract Infection Bacterial Other Serious 9/19/1999 69 Female 110 lb 1/4/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Female 2/3/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 4/10/2006 62 Female 4/24/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2002 61 Female 121 lb 5/12/2006 Physician United States
Primary
Concomitant
Gastroenteritis Hospitalization 4/10/2006 62 Female 5/16/2006 Other Health Professional United States
Primary
Concomitant
Colitis Hospitalization 10/1/2005 Female 5/25/2006 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Other Serious 83 Female 5/19/2006 Physician United States
Primary
Concomitant
Vaginal Cancer Other Serious 7/1/2006 Female 155 lb 8/7/2006 Other Health Professional United States
Primary
Concomitant
Memory Impairment Hospitalization 4/1/2005 86 Female 9/11/2006 Consumer United States
Primary
Concomitant
Vaginal Cancer Other Serious 7/1/2006 Female 155 lb 10/9/2006 Other Health Professional United States
Primary
Concomitant
Uveitis Hospitalization 8/1/2006 Female 216 lb 11/8/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/15/2005 Male 248 lb 12/13/2006 Physician United States
Primary
Concomitant
Nausea 6/9/2006 Female 152 lb 12/13/2006 Other Health Professional United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 4/1/2005 86 Female 108 lb 12/4/2006 Consumer United States
Primary
Concomitant
Localised Infection 6/8/2006 Female 12/21/2006 Consumer United States
Primary
Concomitant
Spinal Fracture Hospitalization 1/1/2004 79 Female 12/26/2006 Consumer United States
Primary
Concomitant
Oedema Other Serious 1/1/2001 Male 190 lb 1/16/2007 Lawyer United States
Primary
Concomitant
Osteonecrosis Other Serious 2/9/2005 69 Female 130 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2006 Female 3/15/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2002 Female 252 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 5/6/2003 57 Female 152 lb 11/27/2006 United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 84 Female 3/27/2007 Consumer United States
Primary
Concomitant
Bursitis Hospitalization 8/20/2006 Female 190 lb 3/27/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2007 Female 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/1/2007 Male 180 lb 7/23/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 2/9/2005 69 Female 130 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 1/1/2000 54 Female 168 lb 2/12/2008 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 2/14/2006 54 Female 201 lb 3/25/2008 Physician United States
Primary
Concomitant
Hypersensitivity Other Serious 11/19/2007 80 Female 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 6/11/2008 Physician United States
Primary
Concomitant
Tuberculin Test Positive 1/1/2007 Female 6/13/2008 Physician United States
Primary
Concomitant
Vertigo Positional Other Serious 1/1/1997 54 Female 168 lb 6/18/2008 Physician United States
Primary
Concomitant
Vertigo Positional Other Serious 1/1/1997 54 Female 168 lb 7/1/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2000 Female 106 lb 7/10/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 140 lb 8/1/2008 Physician United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/9/2008 Male 174 lb 8/7/2008 Physician United States
Primary
Concomitant
Vertigo Positional Other Serious 1/1/1997 54 Female 168 lb 8/13/2008 Physician United States
Primary
Concomitant
Oedema Other Serious 1/1/2001 Male 190 lb 8/28/2008 Lawyer United States
Primary
Concomitant
Post Herpetic Neuralgia Other Serious 12/1/2006 Female 144 lb 9/5/2008 Physician
Primary
Concomitant
Transplant Rejection Other Serious 3/1/2008 65 Female 119 lb 9/15/2008 Physician United States
Primary
Concomitant
Systemic Mycosis Hospitalization 6/3/2008 Female 175 lb 9/16/2008 Consumer United States
Primary
Concomitant
Toe Amputation Other Serious 1/1/2008 Male 174 lb 10/20/2008 Physician United States
Primary
Concomitant
Hernia Hospitalization 12/6/2006 Female 10/22/2008 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/1/2008 Female 121 lb 10/24/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 11/1/2007 Female 11/3/2008 Physician United States
Primary
Concomitant
Vertigo Positional Other Serious 1/1/1997 54 Female 168 lb 11/20/2008 Physician United States
Primary
Concomitant
Localised Infection 2/1/2008 Female 173 lb 12/1/2008 Consumer United States
Primary
Concomitant
Injection Site Swelling 11/8/2007 Female 12/2/2008 Physician United States
Primary
Concomitant
Rash Generalised 2/27/2008 Female 175 lb 12/8/2008 Physician United States
Primary
Concomitant
Weight Decreased Disability 1/1/2001 72 Female 95 lb 11/26/2008 United States
Primary
Secondary
Concomitant
Urinary Tract Infection 5/13/2008 Female 170 lb 12/16/2008 Physician United States
Primary
Concomitant
Glioblastoma Other Serious 8/6/2008 Female 170 lb 1/7/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Sensation Of Heaviness 9/1/2008 Female 1/16/2009 Consumer
Primary
Concomitant
Throat Irritation 4/11/2008 75 Female 121 lb 1/20/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 1/23/2009 Physician United States
Primary
Concomitant
Transplant Rejection Other Serious 3/1/2008 65 Female 119 lb 1/30/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 8/16/2008 Female 103 lb 3/17/2009 United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/2004 75 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/8/2008 Female 194 lb 4/30/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/2/2007 Female 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 1/1/2009 Female 161 lb 6/2/2009 Consumer United States
Primary
Concomitant
Throat Irritation 4/11/2008 75 Female 130 lb 6/4/2009 Consumer United States
Primary
Concomitant
Eye Swelling Other Serious 3/1/2009 Female 163 lb 6/11/2009 Other Health Professional United States
Primary
Concomitant
Influenza Like Illness 5/11/2009 Female 145 lb 6/12/2009 United States
Primary
Concomitant
Synovitis Other Serious 1/1/2006 Female 123 lb 6/18/2009 Physician United States
Primary
Concomitant
Vertigo Positional Other Serious 1/1/1997 46 Female 168 lb 6/29/2009 Physician United States
Primary
Concomitant
Withdrawal Syndrome 1/1/2008 43 Female 145 lb 7/15/2009 Consumer United States
Primary
Concomitant
Generalised Oedema Hospitalization 6/23/2009 Female 316 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Vertigo Positional Other Serious 1/1/1997 46 Female 168 lb 7/29/2009 Physician United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/9/2004 Female 8/14/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 6/1/2007 Female 190 lb 9/11/2009 Consumer United States
Primary
Concomitant
Sinusitis 3/1/2009 Female 147 lb 9/19/2009 Physician United States
Primary
Concomitant
Injection Site Pain 7/25/2009 Female 250 lb 9/19/2009 Consumer United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 71 Female 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Other Serious 6/10/2005 39 Female 10/1/2009 Physician United States
Primary
Secondary
Concomitant
Vertigo Positional Other Serious 1/1/1997 46 Female 168 lb 10/15/2009 Physician United States
Primary
Concomitant
Alveolitis Other Serious 3/1/2009 Female 164 lb 10/27/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/9/2004 Female 11/2/2009 Other Health Professional United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2002 Male 233 lb 11/9/2009 Physician United States
Primary
Concomitant
Myeloid Leukaemia Hospitalization 3/16/2009 Female 178 lb 11/23/2009 Physician United States
Primary
Concomitant
Hair Growth Abnormal 8/7/2008 Female 191 lb 12/1/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/11/2009 71 Female 266 lb 11/25/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 6/19/2003 Female 251 lb 11/30/2009 Consumer United States
Primary
Concomitant
Sinusitis 9/1/2008 Female 218 lb 12/3/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 2/9/2004 Female 12/4/2009 Other Health Professional United States
Primary
Concomitant
Injection Site Swelling 11/25/2008 Female 130 lb 12/4/2009 Physician United States
Primary
Concomitant
Umbilical Hernia 1/1/1998 Male 12/4/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 1/1/2009 Female 149 lb 12/7/2009 Physician United States
Primary
Concomitant
Stress 7/21/2009 Female 12/9/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/29/2009 Female 230 lb 12/15/2009 Physician United States
Primary
Concomitant
Weight Decreased Disability 1/1/2001 72 Female 95 lb 11/25/2009 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2002 Male 233 lb 12/17/2009 Physician United States
Primary
Concomitant
Generalised Oedema Life Threatening 6/23/2009 Female 316 lb 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/4/2009 Female 121 lb 12/16/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/9/2009 Female 121 lb 12/16/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 2/9/2004 Female 12/29/2009 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2004 Female 1/8/2010 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/3/2009 Female 121 lb 1/4/2010 United States
Primary
Concomitant
Osteomyelitis Hospitalization 12/15/2009 Female 158 lb 1/14/2010 Physician United States
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 9/1/2009 Female 170 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 6/10/2005 39 Female 2/15/2010 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 6/10/2005 39 Female 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 2/26/2010 Pharmacist United States
Primary
Concomitant
Wrist Fracture Other Serious 6/10/2005 39 Female 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma 12/30/2009 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 11/9/2009 Female 121 lb 2/10/2010 United States
Primary
Concomitant
Endometrial Cancer Stage Ii Life Threatening 4/29/2008 Female 199 lb 3/11/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 6/10/2005 39 Female 3/15/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 Female 3/17/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2003 Female 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2010 81 Male 234 lb 4/8/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 4/9/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 4/20/2010 Pharmacist United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/22/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/6/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Scleroderma Other Serious 4/27/2010 59 Female 157 lb 5/18/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/19/2010 United States
Primary
Concomitant
Wound Treatment Other Serious 1/1/1997 51 Female 157 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 5/11/2010 34 Female 168 lb 5/21/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/21/2010 United States
Primary
Secondary
Concomitant
Scleroderma Other Serious 4/27/2010 59 Female 157 lb 5/24/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 6/10/2005 39 Female 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2002 42 Female 146 lb 5/28/2010 United States
Primary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 5/28/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 7/30/2003 48 Female 6/2/2010 Pharmacist United States
Primary
Concomitant

Drug Data