Hydrocodone Bitartrate combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 12/25/2005 57 Male 235 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Arthralgia Other Serious 2/1/2005 Female 214 lb 1/20/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/1998 58 Female 196 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Renal Disorder Hospitalization 3/17/2002 62 Female 190 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 6/9/2003 Female 142 lb 2/10/2006 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 46 Female 2/6/2006 United States
Primary
Secondary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2004 60 Male 236 lb 2/24/2006 Physician United States
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 2/23/2004 Male 164 lb 2/28/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2004 60 Male 236 lb 3/1/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 5/9/2005 58 Female 150 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Hospitalization 1/1/2002 52 Male 190 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 9/29/1999 70 Male 209 lb 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/13/2003 56 Female 181 lb 4/14/2006 Lawyer United States
Primary
Concomitant
Renal Disorder Hospitalization 3/18/2002 62 Female 190 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/9/2006 67 Female 4/25/2006 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 4/1/2000 62 Female 190 lb 4/26/2006 Physician United States
Primary
Concomitant
Visual Field Defect Hospitalization 1/1/2002 52 Male 190 lb 5/3/2006 Physician United States
Primary
Concomitant
Visual Field Defect Hospitalization 1/1/2002 52 Male 190 lb 5/9/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2004 57 Male 236 lb 5/17/2006 Physician United States
Primary
Concomitant
Lower Respiratory Tract Inflammation Other Serious 5/1/2006 Female 8/16/2006 Consumer United States
Primary
Concomitant
Shock Hospitalization 6/18/2006 58 Female 8/23/2006 Other Health Professional United States
Primary
Concomitant
Uterine Cancer Other Serious 1/1/2003 Female 9/6/2006 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Death 5/13/2004 Female 100 lb 9/6/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2003 Female 9/7/2006 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/22/2006 Female 9/8/2006 Physician United States
Primary
Concomitant
Tendon Rupture Hospitalization 3/1/2006 Female 210 lb 10/6/2006 Consumer United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 1/9/2006 67 Female 10/12/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/7/2006 Female 10/13/2006 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 12/15/2001 Female 100 lb 10/16/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Female 134 lb 10/16/2006 Physician United States
Primary
Concomitant
T-cell Lymphoma Other Serious 8/23/2003 Female 157 lb 10/16/2006 Physician United States
Primary
Concomitant
Hodgkin's Disease Nodular Sclerosis Stage Iii Other Serious 7/28/2006 Female 108 lb 12/29/2006 Physician United States
Primary
Concomitant
Diarrhoea 7/16/2006 43 Female 135 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/26/2006 Female 171 lb 1/25/2007 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 7/6/2006 42 Female 1/26/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Pulmonary Tuberculosis Hospitalization Female 142 lb 1/31/2007 Physician United States
Primary
Concomitant
Tooth Injury Hospitalization 2/1/2005 Female 6/11/2007 Physician United States
Primary
Concomitant
Neuralgia Other Serious 7/1/2006 Female 148 lb 7/17/2007 Consumer United States
Primary
Concomitant
Rash Papular 7/17/2007 58 Male 205 lb 9/26/2007 Consumer United States
Primary
Concomitant
Dizziness 8/30/2007 64 Female 115 lb 9/26/2007 Consumer United States
Primary
Concomitant
Hyperparathyroidism Other Serious 1/1/2007 Female 11/9/2007 Consumer United States
Primary
Concomitant
Trisomy 8 Other Serious 1/1/2007 Female 200 lb 11/19/2007 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 8/1/2005 59 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2006 Female 148 lb 12/7/2007 Other Health Professional United States
Primary
Concomitant
Urticaria 12/13/2006 Female 12/8/2007 Other Health Professional United States
Primary
Concomitant
Erythema Hospitalization 7/25/2007 65 Female 12/4/2007 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection 7/1/2007 Female 129 lb 12/14/2007 United States
Primary
Concomitant
Rheumatoid Arthritis 8/29/2007 Male 185 lb 12/14/2007 United States
Primary
Concomitant
Skin Laceration 5/1/2007 Female 280 lb 12/14/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 10/1/2007 Female 120 lb 12/15/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/18/2007 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 6/1/1998 53 Female 143 lb 12/20/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/27/2007 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 7/16/2006 44 Female 135 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 6/1/1998 53 Female 143 lb 2/4/2008 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 12/1/2007 Female 2/6/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 Male 224 lb 2/12/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/20/2007 Female 168 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Tooth Loss Other Serious 8/1/2005 59 Female 3/13/2008 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 10/1/2007 Female 93 lb 3/6/2008 Consumer United States
Primary
Concomitant
Herpes Zoster 12/1/2007 Female 173 lb 3/14/2008 United States
Primary
Concomitant
Nasopharyngitis 12/30/2007 Female 138 lb 3/15/2008 Consumer United States
Primary
Concomitant
Drug Ineffective Female 232 lb 3/15/2008 Other Health Professional United States
Primary
Concomitant
Dry Skin Other Serious 10/1/2007 Male 176 lb 3/15/2008 United States
Primary
Concomitant
Rash Macular 10/28/2007 Female 220 lb 3/15/2008 Consumer United States
Primary
Concomitant
Urticaria Other Serious 12/21/2006 Female 179 lb 3/28/2008 Physician United States
Primary
Concomitant
Urticaria Other Serious 3/22/2008 Female 216 lb 4/22/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/20/2007 Female 168 lb 5/2/2008 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 10/1/2007 Female 78 lb 5/12/2008 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 8/1/2005 59 Female 6/9/2008 Other Health Professional United States
Primary
Concomitant
Tooth Loss Other Serious 8/1/2005 59 Female 6/26/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/19/2008 Female 180 lb 8/8/2008 Physician United States
Primary
Concomitant
Ligament Rupture Other Serious 11/1/2007 Female 167 lb 8/12/2008 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 Male 8/12/2008 Physician United States
Primary
Concomitant
Abdominal Discomfort Other Serious 7/19/2008 Female 253 lb 8/25/2008 Physician United States
Primary
Concomitant
Pain Hospitalization 6/1/2008 Female 173 lb 8/28/2008 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 2/1/2005 59 Female 269 lb 9/8/2008 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 5/1/2006 Female 250 lb 9/11/2008 United States
Primary
Concomitant
Virus Serology Test Positive Hospitalization 9/1/2007 Male 180 lb 9/12/2008 Consumer United States
Primary
Concomitant
Contusion 7/3/2008 Female 158 lb 9/12/2008 United States
Primary
Concomitant
Rash 7/2/2008 Female 160 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Factor Increased 5/1/2008 190 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Rheumatoid Factor Increased 6/1/2008 Female 201 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Spinal Compression Fracture 1/1/2007 Female 145 lb 9/12/2008 Consumer United States
Primary
Concomitant
Swelling 11/1/2007 Female 195 lb 9/12/2008 Physician United States
Primary
Concomitant
Musculoskeletal Pain 7/1/2008 Female 123 lb 9/13/2008 Physician
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/19/2008 Female 180 lb 9/25/2008 Physician United States
Primary
Concomitant
Ligament Rupture Other Serious 11/1/2007 Female 167 lb 9/26/2008 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious Female 10/27/2008 Physician United States
Primary
Concomitant
Gastrointestinal Obstruction Other Serious 7/19/2008 Female 253 lb 10/30/2008 Physician United States
Primary
Concomitant
Swelling Other Serious Female 10/31/2008 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2007 Female 11/26/2008 Physician United States
Primary
Concomitant
Ventricular Extrasystoles 9/26/2008 53 Female 11/26/2008 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 7/1/2008 73 Female 12/2/2008 Physician United States
Primary
Concomitant
Stress Fracture Hospitalization 9/1/2007 Female 12/8/2008 Physician United States
Primary
Concomitant
Pneumonia 12/1/2007 Female 12/11/2008 Consumer United States
Primary
Concomitant
Pain 4/14/2008 Female 12/11/2008 Physician United States
Primary
Concomitant
No Therapeutic Response 4/1/2008 Female 170 lb 12/12/2008 Physician United States
Primary
Concomitant
Sjogren's Syndrome 5/1/2008 Female 200 lb 12/12/2008 United States
Primary
Concomitant
Injection Site Irritation 4/1/2008 Male 245 lb 12/12/2008 United States
Primary
Concomitant
Pain In Extremity 2/1/2008 Male 330 lb 12/12/2008 United States
Primary
Concomitant
Rash 12/1/2007 Female 170 lb 12/12/2008 Consumer United States
Primary
Concomitant
Procedural Complication 6/1/2008 Female 230 lb 12/12/2008 Consumer United States
Primary
Concomitant
Skin Infection 9/1/2008 Male 12/12/2008 Consumer United States
Primary
Concomitant
Procedural Complication Female 193 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis 10/21/2008 Female 182 lb 12/12/2008 United States
Primary
Concomitant
Incorrect Dose Administered Male 12/12/2008 Consumer United States
Primary
Concomitant
Upper Limb Fracture 1/1/2008 Female 12/13/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection 11/16/2005 Female 12/15/2008 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 7/1/2008 73 Female 12/16/2008 Physician United States
Primary
Concomitant
Urticaria 1/1/2006 Female 155 lb 12/16/2008 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Disability 7/1/2008 Female 236 lb 12/23/2008 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 10/22/2008 Male 187 lb 1/16/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Psoriasis Hospitalization Male 380 lb 2/20/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection 10/25/2008 Female 3/14/2009 United States
Primary
Concomitant
Rectal Haemorrhage 11/1/2008 Female 189 lb 3/14/2009 United States
Primary
Secondary
Concomitant
Sleep Disorder 11/1/2008 Female 200 lb 3/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 1/1/2008 Female 3/14/2009 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 3/18/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 4/1/2009 Physician United States
Primary
Concomitant
Death Death 2/1/2009 52 Male 303 lb 4/7/2009 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 5/22/2009 74 Female 5/28/2009 Other Health Professional United States
Primary
Concomitant
Vomiting 1/2/2009 51 Female 148 lb 5/18/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 3/10/2009 Female 271 lb 5/29/2009 Physician United States
Primary
Secondary
Concomitant
Procedural Complication 6/1/2008 Female 230 lb 6/11/2009 Consumer United States
Primary
Concomitant
Eye Infection Staphylococcal 3/7/2009 Female 188 lb 6/11/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 1/1/2009 Female 138 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Pruritus 3/31/2009 Female 200 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pain Male 185 lb 6/12/2009 Physician United States
Primary
Concomitant
Tooth Fracture 10/1/2008 Female 160 lb 6/12/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 4/27/2009 Male 256 lb 6/12/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2009 Female 6/12/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 5/8/2009 Male 216 lb 6/12/2009 Consumer United States
Primary
Concomitant
Muscular Weakness 2/1/2009 Male 190 lb 6/12/2009 Physician United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 6/8/2009 Female 145 lb 6/17/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 12/1/2007 Female 200 lb 7/1/2009 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Disability 7/1/2008 Female 236 lb 7/10/2009 Physician United States
Primary
Concomitant
Unevaluable Event Death Male 8/28/2009 United States
Primary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Incorrect Dose Administered 10/10/2006 Male 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 4/1/2007 Female 229 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 3/3/2008 Female 164 lb 9/12/2009 Consumer United States
Primary
Concomitant

Drug Data