Ketoprofen combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Other Serious 12/25/2003 56 Female 101 lb 1/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemorrhagic Cerebral Infarction Hospitalization 2/14/2004 60 Female 2/7/2006 Other Health Professional Sweden
Primary
Concomitant
Cerebral Infarction Hospitalization 2/14/2004 60 Female 2/10/2006 Other Health Professional Sweden
Primary
Concomitant
Diarrhoea Hospitalization 6/8/2004 Male 123 lb 2/15/2006 France
Primary
Concomitant
Weight Decreased Other Serious 9/27/2004 Male 2/17/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/5/2005 62 Female 5/20/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Eosinophilia Other Serious 7/1/2001 55 Female 3/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumococcal Sepsis Death 1/24/2006 Female 126 lb 4/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 1/17/2006 Female 126 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Feeling Abnormal Other Serious 3/17/2006 Male 132 lb 4/25/2006 Pharmacist France
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/5/2006 70 Female 6/20/2006 Consumer Australia
Primary
Concomitant
Gastric Haemorrhage Other Serious 6/5/2006 70 Female 6/30/2006 Physician Australia
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Cellulitis Other Serious 6/10/2005 Female 119 lb 7/19/2006 France
Primary
Concomitant
Pneumococcal Sepsis Death 1/24/2006 Female 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/17/2006 Female 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/15/2005 Female 130 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thalamic Infarction Hospitalization 11/29/2005 53 Female 159 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Suture Rupture Hospitalization 9/18/2006 Male 171 lb 10/16/2006 Physician Japan
Primary
Concomitant
Vasculitis Hospitalization 45 Female 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/18/2006 Male 171 lb 11/2/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2004 66 Female 11/22/2006 France
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/18/2006 Male 171 lb 11/27/2006 Physician Japan
Primary
Concomitant
Neck Pain Hospitalization 8/19/2006 Male 11/29/2006 Physician Japan
Primary
Concomitant
Tuberculosis Life Threatening 7/1/2006 Male 192 lb 11/30/2006 Physician France
Primary
Concomitant
Mediastinal Abscess Hospitalization 9/27/2006 Male 12/12/2006 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/18/2006 Male 171 lb 1/26/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 10/1/2005 Male 1/29/2007 Physician Sweden
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/18/2006 Male 171 lb 2/9/2007 Physician Japan
Primary
Concomitant
B-cell Small Lymphocytic Lymphoma Hospitalization 64 Male 2/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
Fall Hospitalization 7/10/2005 Male 157 lb 3/7/2007 Consumer United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/8/2006 56 Female 2/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/8/2006 56 Female 3/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/1/2007 Female 108 lb 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Death Death Female 101 lb 4/11/2007 Physician Japan
Primary
Concomitant
Metrorrhagia Other Serious 1/1/2005 60 Female 4/12/2007 Other Health Professional France
Primary
Concomitant
Pleural Effusion Hospitalization 3/1/2007 Female 108 lb 4/12/2007 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/16/2007 Female 108 lb 4/20/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 6/5/2005 Female 110 lb 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Metrorrhagia Other Serious 4/1/2005 60 Female 4/20/2007 Other Health Professional France
Primary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Carcinoid Tumour Of The Appendix Other Serious 8/2/2006 Male 170 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 4/30/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 3/16/2007 Female 108 lb 5/1/2007 Physician Japan
Primary
Concomitant
Reflux Oesophagitis Hospitalization 3/4/2007 Female 146 lb 5/1/2007 Physician Japan
Primary
Secondary
Concomitant
Guillain-barre Syndrome Hospitalization 11/20/2006 Female 132 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/16/2007 Female 108 lb 5/22/2007 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 3/16/2007 Female 108 lb 6/5/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/4/2007 Female 146 lb 6/11/2007 Physician Japan
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 6/15/2005 Male 159 lb 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/22/2006 Male 151 lb 6/15/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 9/30/2005 63 Female 139 lb 6/15/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Guillain-barre Syndrome Hospitalization 11/20/2006 Female 132 lb 6/21/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/27/2004 Male 6/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Ureteric Cancer Other Serious 3/7/2007 Female 95 lb 7/24/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 6/5/2005 Female 110 lb 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Tuberculosis Hospitalization 11/1/2003 Female 8/16/2007 Sweden
Primary
Concomitant
Pneumonia Life Threatening 11/15/2006 Male 151 lb 10/15/2007 Physician United Kingdom
Primary
Concomitant
Cerebral Haemorrhage Death 6/9/2007 Male 11/14/2007 Physician New Zealand
Primary
Concomitant
Axonal Neuropathy Other Serious 1/1/2007 Male 154 lb 11/21/2007 Physician France
Primary
Concomitant
Brain Neoplasm Life Threatening 9/15/2007 62 Male 12/5/2007 Other Health Professional France
Primary
Concomitant
Injection Site Reaction 7/1/2007 Female 12/10/2007 Other Health Professional United States
Primary
Concomitant
Lichen Planus Other Serious 10/1/2004 Female 12/17/2007 Physician France
Primary
Concomitant
Hypoxia Hospitalization 12/8/2006 56 Female 12/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 6/9/2007 Male 1/25/2008 Physician New Zealand
Primary
Concomitant
Brain Neoplasm Life Threatening 9/15/2007 Male 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/30/2005 Female 139 lb 2/12/2008 Physician Japan
Primary
Secondary
Concomitant
Meningioma Life Threatening 9/15/2007 Male 3/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Meningioma Life Threatening 9/15/2007 Male 3/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/30/2005 Female 139 lb 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 187 lb 3/28/2008 Brazil
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/19/2008 Female 4/9/2008 Belgium
Primary
Secondary
Concomitant
Vaginal Infection Hospitalization 5/30/2006 Female 137 lb 4/16/2008 Physician Italy
Primary
Secondary
Concomitant
Vasculitis Hospitalization 4/8/2008 Male 163 lb 5/5/2008 Consumer United Kingdom
Primary
Concomitant
Hypoxia Hospitalization 12/8/2006 Female 5/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death Female 101 lb 5/23/2008 Physician Japan
Primary
Concomitant
Nausea Hospitalization 3/19/2008 Female 6/6/2008 Belgium
Primary
Secondary
Concomitant
Pancytopenia Other Serious Male 6/11/2008 Other Health Professional Japan
Primary
Interacting
Cholelithiasis Hospitalization 11/3/2005 Female 7/3/2008 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 67 Female 7/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tympanic Membrane Perforation Other Serious 4/1/2008 Male 141 lb 7/11/2008 Brazil
Primary
Concomitant
Pyrexia Hospitalization 7/3/2008 Female 115 lb 7/11/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Cholelithiasis Hospitalization 11/3/2005 Female 7/18/2008 Physician United States
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/18/2008 Japan
Primary
Concomitant
Prostatitis Hospitalization 6/25/2008 52 Male 7/18/2008 Consumer United Kingdom
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 7/25/2008 Japan
Primary
Concomitant
Bowen's Disease Other Serious 3/20/2008 64 Female 190 lb 8/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization 10/1/2007 67 Female 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 8/16/2008 Female 9/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 9/24/2008 Japan
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 10/17/2008 Japan
Primary
Concomitant
Tympanic Membrane Perforation Other Serious 4/1/2008 Male 141 lb 10/29/2008 Brazil
Primary
Concomitant
Hypersensitivity Other Serious 8/2/2008 Female 10/29/2008 Belgium
Primary
Concomitant
Hypersensitivity Other Serious 8/2/2008 Female 11/24/2008 Belgium
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 187 lb 12/2/2008 Brazil
Primary
Concomitant
Sepsis Other Serious 2/3/2003 69 Male 12/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 8/22/2008 Female 12/16/2008 Japan
Primary
Concomitant
Sepsis Other Serious 8/22/2008 Female 12/18/2008 Japan
Primary
Secondary
Concomitant
Partial Seizures Other Serious 12/1/2007 50 Female 12/19/2008 Consumer Australia
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2008 Female 115 lb 12/19/2008 Japan
Primary
Concomitant
Convulsion Other Serious 12/6/2007 50 Female 1/2/2009 Consumer Australia
Primary
Concomitant
Fall Other Serious 12/6/2007 50 Female 1/7/2009 Consumer Australia
Primary
Concomitant
Convulsion Other Serious 12/6/2007 50 Female 1/30/2009 Consumer Australia
Primary
Concomitant
Septic Shock Hospitalization 1/18/2009 68 Male 2/12/2009 Physician France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 8/22/2008 Female 3/3/2009 Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 12/6/2007 50 Female 3/18/2009 Consumer Australia
Primary
Concomitant
Sepsis Other Serious 8/22/2008 Female 3/25/2009 Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/18/2009 68 Male 3/26/2009 Physician France
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 1/23/2009 Female 132 lb 4/6/2009 Japan
Primary
Concomitant
Death Other Serious 69 Male 187 lb 4/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/17/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/22/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 4/22/2009 Japan
Primary
Concomitant
Gait Disturbance Hospitalization 11/5/2008 Female 121 lb 4/24/2009 Japan
Primary
Concomitant
Hernial Eventration Hospitalization 10/6/2008 Female 4/24/2009 Consumer United Kingdom
Primary
Concomitant
Gait Disturbance Hospitalization 11/5/2008 Female 121 lb 5/1/2009 Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 5/4/2009 Japan
Primary
Concomitant
Lung Neoplasm Malignant Other Serious Male 187 lb 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 1/16/2009 Male 157 lb 5/12/2009 United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/27/2009 35 Female 345 lb 5/21/2009 Physician United States
Primary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 5/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 3/10/2009 Female 111 lb 6/1/2009 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 1/23/2009 Female 132 lb 6/5/2009 Japan
Primary
Concomitant
Sepsis Other Serious 2/3/2003 69 Male 6/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Other Serious 12/6/2007 49 Female 6/19/2009 Consumer Australia
Primary
Concomitant
Respiratory Failure Hospitalization 3/10/2009 Female 111 lb 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Hospitalization 4/8/2008 Male 163 lb 6/26/2009 Consumer United Kingdom
Primary
Concomitant
Vasculitis Hospitalization 4/8/2008 Male 163 lb 7/7/2009 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/1/2002 64 Female 7/8/2009
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 7/15/2009 Female 145 lb 7/28/2009 Physician Poland
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 3/24/2009 Female 7/31/2009 Japan
Primary
Concomitant
Multiple Sclerosis Hospitalization 7/15/2009 Female 145 lb 8/3/2009 Physician Poland
Primary
Secondary
Concomitant
Anogenital Warts Hospitalization 1/1/2008 Female 8/3/2009 Germany
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 7/15/2009 Female 145 lb 8/24/2009 Physician Poland
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/14/2009 Female 132 lb 8/26/2009 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/9/2009 75 Female 9/8/2009 Physician Sweden
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 5/28/2009 71 Female 126 lb 9/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lung Cancer Metastatic Other Serious 4/28/2008 Male 187 lb 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis 4/5/2009 Female 126 lb 9/18/2009 United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 7/15/2009 Female 145 lb 9/22/2009 Physician Poland
Primary
Secondary
Concomitant
Vasculitis Hospitalization 4/8/2008 Male 163 lb 9/28/2009 Consumer France
Primary
Concomitant
Rash Macular Other Serious 2/1/2008 Female 200 lb 10/1/2009 Canada
Primary
Concomitant
Lung Cancer Metastatic Other Serious 8/28/2008 Male 187 lb 10/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/13/2009 Other Health Professional France
Primary
Secondary
Concomitant
Meningioma Hospitalization 9/15/2007 Male 10/23/2009 Other Health Professional France
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 9/14/2009 44 Female 11/12/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 1/27/2009 35 Female 345 lb 12/1/2009 Physician United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 10/15/2009 Female 236 lb 12/10/2009 Sweden
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 176 lb 12/11/2009 Brazil
Primary
Concomitant

Drug Data