Methotrexate combined with Vioxx

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Life Threatening 6/1/2003 Female 144 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 8/28/2003 73 Female 258 lb 1/4/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/2000 75 Male 181 lb 1/4/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Other Serious 9/19/1999 69 Female 110 lb 1/4/2006 Physician United States
Primary
Concomitant
Cardiac Disorder Hospitalization 1/1/2002 67 Female 179 lb 1/5/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 11/10/1999 39 Female 139 lb 1/10/2006 Physician United States
Primary
Concomitant
Ischaemic Stroke Other Serious 5/1/2002 48 Male 190 lb 1/10/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/15/2000 45 Male 194 lb 1/10/2006 Physician United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/1/2000 52 Male 150 lb 1/10/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2003 44 Male 1/12/2006 Norway
Primary
Concomitant
Unevaluable Event Hospitalization 1/1/1999 49 Male 185 lb 1/12/2006 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization 12/15/2005 53 Male 1/13/2006 Other Health Professional United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 1/13/2006 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious Female 1/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Hospitalization 10/26/2002 60 Male 170 lb 1/17/2006 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/1/1999 49 Male 185 lb 1/17/2006 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 5/17/2003 68 Male 194 lb 1/18/2006 Physician United States
Primary
Concomitant
Sinus Disorder Hospitalization 11/26/2002 72 Female 181 lb 1/19/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/7/2001 73 Female 154 lb 1/20/2006 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2004 52 Female 150 lb 1/20/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/29/2001 55 Female 148 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Uterine Disorder Hospitalization 7/1/2000 44 Female 148 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious Male 205 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Skin Disorder Other Serious 10/22/2002 75 Female 185 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 11/1/2000 50 Male 196 lb 1/23/2006 Physician United States
Primary
Concomitant
Renal Disorder Hospitalization 3/17/2002 62 Female 190 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 65 Female 141 lb 1/23/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 12/1/2003 76 Male 190 lb 1/23/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 12/1/2001 75 Female 148 lb 1/23/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 3/1/2000 48 Female 150 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 1/1/2003 61 Female 143 lb 1/24/2006 Physician United States
Primary
Secondary
Ventricular Hypertrophy Other Serious 1/1/2003 62 Female 115 lb 1/24/2006 Physician United States
Primary
Concomitant
Rash Other Serious 11/1/2003 75 Male 185 lb 1/24/2006 Physician United States
Primary
Concomitant
Palpitations Other Serious 1/1/2002 67 Female 214 lb 1/25/2006 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/1/2000 51 Male 231 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 12/14/2005 53 Male 1/31/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2000 69 Male 295 lb 2/3/2006 Physician United States
Primary
Concomitant
Ulcer Hospitalization 1/1/2002 63 Male 205 lb 2/3/2006 Physician United States
Primary
Concomitant
Multiple Fractures Hospitalization 2/2/2004 64 Female 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Haemorrhagic Cerebral Infarction Hospitalization 2/14/2004 60 Female 2/7/2006 Other Health Professional Sweden
Primary
Concomitant
Vasospasm Other Serious 7/1/2002 42 Female 161 lb 2/6/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/15/2003 66 Male 190 lb 2/7/2006 Lawyer United States
Primary
Concomitant
Vertigo Other Serious 12/4/2001 Female 2/9/2006 Physician United States
Primary
Concomitant
Cerebral Infarction Hospitalization 2/14/2004 60 Female 2/10/2006 Other Health Professional Sweden
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 28 Female 2/13/2006 Lawyer United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 2/19/2003 53 Female 141 lb 2/13/2006 Physician United States
Primary
Concomitant
Postoperative Wound Infection Other Serious Female 210 lb 2/7/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 9/28/2004 66 Male 2/13/2006 Norway
Primary
Concomitant
Wound Drainage Hospitalization 1/5/2004 50 Male 2/14/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 11/1/2000 50 Male 196 lb 2/14/2006 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 7/18/2003 61 Male 2/16/2006 Norway
Primary
Concomitant
Thrombosis Life Threatening 9/28/2004 66 Male 2/16/2006 Norway
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 53 Male 300 lb 2/17/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2000 67 Male 154 lb 2/17/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2002 52 Female 240 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2002 47 Female 240 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 3/6/2001 59 Female 134 lb 2/21/2006 Physician Germany
Primary
Concomitant
Rotator Cuff Repair Hospitalization 2/1/2001 37 Male 196 lb 2/21/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2003 59 Female 128 lb 2/21/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2000 69 Male 295 lb 2/21/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 61 Female 2/21/2006 Physician United States
Primary
Concomitant
Hypotension Hospitalization 10/26/2002 60 Male 170 lb 2/22/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 57 Male 225 lb 2/22/2006 Lawyer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 2/1/2003 73 Female 110 lb 2/22/2006 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Life Threatening 7/18/2003 61 Male 2/23/2006 Other Health Professional Norway
Primary
Concomitant
Raynaud's Phenomenon Hospitalization 1/1/2001 70 Female 141 lb 2/23/2006 Lawyer United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 7/18/2003 61 Male 2/23/2006 Norway
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Vascular Dementia Hospitalization 1/1/2000 74 Male 99 lb 2/23/2006 Physician United States
Primary
Concomitant
Thyroid Disorder Disability 10/1/2002 41 Male 165 lb 2/24/2006 Physician United States
Primary
Concomitant
Hypertension Other Serious 11/19/2001 51 Male 2/24/2006 Physician Germany
Primary
Concomitant
Wheezing Other Serious 1/19/2001 69 Female 115 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/1/2004 60 Male 236 lb 2/24/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 1/1/2003 61 Female 143 lb 2/27/2006 Physician United States
Primary
Secondary
Concomitant
Ulcer Haemorrhage Life Threatening 7/18/2003 61 Male 2/27/2006 Other Health Professional Norway
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 2/27/2004 49 Male 231 lb 2/27/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 2/27/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 1/1/2004 58 Female 154 lb 2/27/2006 Lawyer United States
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/1999 37 Female 148 lb 2/28/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 2/1/2004 Male 2/28/2006 Physician Norway
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 9/29/1999 70 Male 209 lb 2/28/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/19/2002 41 Female 150 lb 3/1/2006 Physician United States
Primary
Concomitant
Tuberculosis Hospitalization 10/3/2004 Female 3/1/2006 Other Health Professional Norway
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2004 Male 3/1/2006 Physician Norway
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 1/1/2000 51 Male 231 lb 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 12/7/2002 32 Female 170 lb 3/1/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2004 60 Male 236 lb 3/1/2006 Physician United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 6/1/2003 Male 231 lb 3/2/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/11/2001 69 Female 115 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 2/13/2004 63 Male 192 lb 3/2/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2000 50 Male 196 lb 3/3/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 61 Female 3/6/2006 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 4/20/2000 56 Female 126 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/17/2001 68 Male 190 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Emotional Disorder Hospitalization 5/1/2004 32 Female 3/7/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 40 Female 231 lb 3/7/2006 Lawyer United States
Primary
Concomitant
Tuberculosis Hospitalization 10/3/2004 Female 3/7/2006 Physician Norway
Primary
Secondary
Concomitant
Tendonitis Hospitalization 8/16/1999 79 Female 234 lb 3/7/2006 Physician United States
Primary
Concomitant
Blood Pressure Decreased Death 2/13/2005 64 Male 223 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertebral Artery Occlusion Hospitalization 9/29/1999 70 Male 209 lb 3/8/2006 Physician United States
Primary
Concomitant
Prostatic Disorder Other Serious 1/1/2003 72 Male 170 lb 3/8/2006 Physician United States
Primary
Concomitant
Sputum Discoloured Hospitalization 11/26/2002 72 Female 181 lb 3/10/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2004 49 Male 231 lb 3/13/2006 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2005 86 Female 90 lb 11/3/2005 United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2001 83 Female 3/13/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 59 Male 159 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Visual Disturbance Hospitalization 8/14/2003 60 Male 3/8/2006 Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 66 Male 201 lb 3/14/2006 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 12/5/2003 67 Male 179 lb 3/17/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/10/2003 58 Female 183 lb 3/17/2006 Lawyer United States
Primary
Concomitant
Thrombosis Hospitalization 6/6/2000 43 Female 205 lb 3/20/2006 Physician United States
Primary
Concomitant
Viral Pharyngitis Other Serious 1/1/2000 51 Male 231 lb 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Wound Drainage Hospitalization 1/1/2003 50 Male 220 lb 3/21/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 64 Female 161 lb 3/22/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/1/2004 81 Female 181 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Sinus Disorder Hospitalization 11/26/2002 72 Female 181 lb 3/22/2006 Physician United States
Primary
Concomitant
Sedation Hospitalization 6/16/2003 49 Female 231 lb 3/23/2006 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/2003 54 Male 201 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 59 Male 159 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Swelling 12/1/2005 Male 252 lb 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2000 50 Male 196 lb 3/24/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Visual Field Defect Hospitalization 1/1/2002 52 Male 190 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2002 47 Female 240 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 67 Female 110 lb 3/27/2006 Physician United States
Primary
Concomitant
Infection Hospitalization 1/1/2003 60 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 61 Female 110 lb 3/27/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 41 Female 150 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 11/20/2003 71 Female 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Bone Neoplasm Malignant Other Serious 12/1/2004 Male 3/28/2006 Physician United States
Primary
Concomitant
Tuberculosis Hospitalization 10/3/2004 Female 3/28/2006 Physician Norway
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2000 58 Female 141 lb 3/28/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/29/1999 70 Male 209 lb 3/29/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2002 57 Male 225 lb 3/29/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2001 83 Female 3/30/2006 Physician United States
Primary
Concomitant
Death Death 11/21/2005 Male 128 lb 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 61 Female 170 lb 3/30/2006 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Death 5/21/2004 62 Male 220 lb 3/31/2006 Lawyer United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 2/19/2003 53 Female 141 lb 4/3/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 4/10/2003 77 Female 154 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Sinus Disorder Hospitalization 11/26/2002 72 Female 181 lb 4/4/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 12/4/2001 54 Female 181 lb 4/4/2006 Physician United States
Primary
Concomitant
Nasal Septum Deviation Hospitalization 10/1/2002 52 Male 218 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/1999 50 Male 240 lb 4/5/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 1/1/2003 61 Female 143 lb 4/5/2006 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2002 66 Male 201 lb 4/6/2006 Lawyer United States
Primary
Concomitant

Drug Data