Methotrexate combined with Verapamil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abdominal Abscess Hospitalization 11/8/2004 Female 148 lb 1/25/2006 Netherlands
Primary
Concomitant
Sjogren's Syndrome Other Serious Female 1/31/2006 United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death Female 2/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/1/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/8/2006 Physician Japan
Primary
Concomitant
Oral Intake Reduced Other Serious 1/1/2005 61 Male 2/21/2006 Consumer New Zealand
Primary
Concomitant
Pleural Effusion Life Threatening 1/30/2006 56 Female 146 lb 2/17/2006 Physician Serbia And Montenegro
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/27/2006 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/12/2006 61 Female 2/27/2006 Physician Serbia And Montenegro
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 1/30/2006 56 Female 146 lb 2/27/2006 Physician Yugoslavia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 3/2/2006 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 59 Male 159 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2002 Female 226 lb 3/13/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 59 Male 159 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Sjogren's Syndrome Other Serious Female 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2000 47 Female 161 lb 5/1/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2000 47 Female 161 lb 5/8/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2003 57 Male 5/9/2006 Australia
Primary
Concomitant
Cardiomyopathy Hospitalization 11/9/2005 Female 210 lb 5/15/2006 Physician United States
Primary
Concomitant
Infusion Related Reaction Other Serious 3/16/2006 62 Female 5/15/2006 Physician Norway
Primary
Concomitant
Infusion Related Reaction Other Serious 3/16/2006 62 Female 5/16/2006 Physician Norway
Primary
Concomitant
Renal Failure Other Serious 4/26/2006 Female 276 lb 5/30/2006 Physician Germany
Primary
Secondary
Concomitant
Haemoptysis Other Serious 8/1/2004 46 Female 163 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Ratio Increased 1/1/2005 57 Female 201 lb 8/1/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 1/1/2006 Female 156 lb 8/18/2006 Consumer United States
Primary
Secondary
Concomitant
Sepsis Death Male 9/11/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 4/26/2006 Female 276 lb 10/3/2006 Physician Germany
Primary
Secondary
Concomitant
Injection Site Bruising 9/12/2006 Female 291 lb 12/20/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2006 59 Female 143 lb 11/28/2006 Physician United States
Primary
Concomitant
Oesophageal Adenocarcinoma Death Male 1/25/2007 Physician United States
Primary
Concomitant
Migraine Hospitalization 1/1/2004 Female 140 lb 2/6/2007 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/1/2007 Male 168 lb 5/30/2007 Physician United States
Primary
Concomitant
Tooth Injury Hospitalization 2/1/2005 Female 6/11/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 6/18/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Death Death Female 97 lb 7/19/2007 Other Health Professional Canada
Primary
Concomitant
Herpes Zoster Hospitalization 8/29/2007 Female 9/20/2007 Physician United States
Primary
Concomitant
Hypercalcaemia Other Serious 1/1/2007 Female 9/20/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 8/22/2007 Female 165 lb 9/21/2007 Canada
Primary
Concomitant
Skin Lesion Hospitalization 8/22/2007 Female 165 lb 10/4/2007 Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 6/23/2007 Female 154 lb 10/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/11/2007 86 Male 141 lb 11/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperparathyroidism Other Serious 1/1/2007 Female 11/9/2007 Consumer United States
Primary
Concomitant
Erythema 9/17/2007 Female 150 lb 12/14/2007 United States
Primary
Concomitant
Rash 1/1/2005 Female 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Ocular Hyperaemia 10/1/2007 Male 180 lb 12/14/2007 United States
Primary
Concomitant
Thrombosis Hospitalization 9/20/2007 60 Female 200 lb 12/5/2007 United States
Primary
Concomitant
Thrombosis Hospitalization 9/20/2007 60 Female 200 lb 1/3/2008 United States
Primary
Concomitant
Thyroid Neoplasm Required Intervention 9/20/2007 60 Female 200 lb 2/21/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Required Intervention 9/20/2007 60 Female 200 lb 2/29/2008 Physician United States
Primary
Concomitant
Dry Skin 10/1/2003 Female 169 lb 3/14/2008 United States
Primary
Concomitant
Constipation 1/11/2008 Female 234 lb 3/15/2008 United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2008 79 Female 4/22/2008 Consumer Colombia
Primary
Concomitant
Erythema Nodosum Other Serious 7/1/2007 Female 148 lb 4/28/2008 United States
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 4/23/2007 Male 5/8/2008 Consumer United States
Primary
Concomitant
Peripheral Vascular Disorder Other Serious 4/8/2003 Female 6/6/2008 Physician
Primary
Secondary
Concomitant
Sinusitis 2/27/2008 Female 128 lb 6/12/2008 Consumer United States
Primary
Concomitant
Sensory Loss 2/1/2008 Male 280 lb 6/13/2008 United States
Primary
Concomitant
Drug Ineffective 3/1/2008 Female 138 lb 6/13/2008 Consumer United States
Primary
Concomitant
Stress 4/5/2008 Female 176 lb 6/13/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 5/11/2008 Female 145 lb 6/13/2008 Consumer United States
Primary
Concomitant
Metastatic Carcinoid Tumour Hospitalization 9/26/2007 Female 193 lb 6/19/2008 United States
Primary
Concomitant
Pyrexia 1/1/2008 65 Female 185 lb 6/30/2008 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 4/8/2003 Female 7/2/2008 Physician
Primary
Secondary
Concomitant
Toe Amputation Hospitalization 12/12/2005 Female 7/3/2008 Physician
Primary
Concomitant
Vomiting Hospitalization 11/1/2007 79 Female 7/24/2008 Consumer Colombia
Primary
Concomitant
Skin Ulcer Other Serious 4/8/2003 53 Female 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Other Serious 11/7/2007 Female 234 lb 9/12/2008 Physician United States
Primary
Concomitant
Emphysema 5/1/2008 Female 200 lb 9/13/2008 United States
Primary
Secondary
Concomitant
Migraine Other Serious 1/1/2007 Female 215 lb 9/18/2008 Consumer United States
Primary
Concomitant
Pruritus Hospitalization 9/1/2007 29 Female 9/25/2008 Other Health Professional United States
Primary
Concomitant
Organising Pneumonia Hospitalization 11/9/2007 Male 167 lb 10/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metastatic Carcinoid Tumour Other Serious 9/9/2007 Female 193 lb 10/24/2008 United States
Primary
Concomitant
Organising Pneumonia Hospitalization 11/9/2007 65 Male 167 lb 11/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Disorientation Other Serious 10/1/2008 Female 189 lb 11/10/2008 Consumer United States
Primary
Concomitant
Carotid Artery Stenosis Other Serious Female 178 lb 11/21/2008 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 11/26/2008 Consumer Colombia
Primary
Concomitant
Traumatic Brain Injury Hospitalization 10/24/2008 Male 209 lb 12/8/2008 Physician Romania
Primary
Secondary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 12/2/2008 Consumer Colombia
Primary
Concomitant
Uterine Cancer Other Serious 10/5/2008 Female 276 lb 12/12/2008 Consumer United States
Primary
Concomitant
Emphysema 5/1/2008 Female 200 lb 12/12/2008
Primary
Secondary
Concomitant
Injection Site Pain 9/9/2008 Female 162 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 8/1/2008 Female 237 lb 12/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2008 Female 140 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 1/1/2003 Female 254 lb 12/13/2008 Physician United States
Primary
Concomitant
Skin Ulcer 7/26/2008 Female 170 lb 12/15/2008 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/1/2007 Female 150 lb 12/26/2008 Physician Netherlands
Primary
Concomitant
Pneumonia 1/1/2005 Female 202 lb 3/14/2009 Consumer United States
Primary
Concomitant
Tenosynovitis Other Serious 8/1/2007 73 Male 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2005 Female 202 lb 6/11/2009 United States
Primary
Concomitant
Psoriatic Arthropathy 2/1/2009 Female 145 lb 6/12/2009 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Death 12/24/2007 Female 6/12/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 1/1/2005 Female 202 lb 6/15/2009 United States
Primary
Concomitant
Medication Residue Other Serious Female 6/25/2009 Pharmacist France
Primary
Concomitant
Palpitations Hospitalization 83 Female 170 lb 7/2/2009 United States
Primary
Concomitant
Total Lung Capacity Decreased Hospitalization Male 7/28/2009 Consumer United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/4/2009 77 Female 8/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 7/29/2009 74 Female 8/20/2009 Physician Israel
Primary
Concomitant
Total Lung Capacity Decreased Hospitalization 6/15/2009 Male 8/26/2009 Consumer Australia
Primary
Concomitant
Total Lung Capacity Decreased Hospitalization 6/15/2009 Male 9/1/2009 Consumer Australia
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/9/2007 Female 155 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Irritation 7/27/2007 Female 249 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Extravasation 3/1/2008 Female 138 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 5/11/2008 Female 145 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 9/9/2008 Female 162 lb 9/12/2009 Consumer United States
Primary
Concomitant
Sinus Disorder 6/26/2009 Female 132 lb 9/19/2009 Consumer United States
Primary
Concomitant
Injection Site Rash Hospitalization Female 9/19/2009 Physician United States
Primary
Concomitant
Panic Attack 5/1/2009 Female 175 lb 9/19/2009 Consumer United States
Primary
Concomitant
Tachycardia Life Threatening 9/4/2009 Female 157 lb 11/23/2009 Physician United States
Primary
Secondary
Concomitant
Skin Burning Sensation 10/28/2009 Female 190 lb 11/25/2009 Consumer United States
Primary
Concomitant
Skin Ulcer 3/1/2009 Female 11/25/2009 Physician United States
Primary
Concomitant
Urticaria 3/1/2008 Female 226 lb 12/1/2009 Physician United States
Primary
Concomitant
Ulcer 11/18/2008 Female 12/2/2009 Physician United States
Primary
Concomitant
Sinusitis 11/24/2008 Female 168 lb 12/2/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2007 79 Female 12/1/2009 Consumer Colombia
Primary
Concomitant
Nodule 3/4/2009 Female 203 lb 12/8/2009 Physician United States
Primary
Concomitant
Pain In Extremity 7/1/2009 Female 12/9/2009 Physician United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 9/4/2009 Female 157 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Oral Herpes 9/28/2009 Male 1/30/2010 Pharmacist United States
Primary
Concomitant
Injection Site Urticaria 11/1/2009 Female 155 lb 1/30/2010 United States
Primary
Concomitant
Drug Ineffective 60 Female 165 lb 2/22/2010 Consumer United States
Primary
Concomitant
Uterine Leiomyoma Hospitalization 4/21/2009 42 Female 223 lb 5/19/2010 Physician Lithuania
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 4/21/2009 42 Female 223 lb 5/25/2010 Lithuania
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 5/4/2009 77 Female 157 lb 6/14/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vestibular Disorder Congenital Anomaly 11/1/2009 84 Male 6/11/2010 Physician Japan
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 2/15/2010 69 Male 192 lb 6/18/2010 Physician United Kingdom
Primary
Concomitant
Tooth Infection Other Serious 10/1/2007 63 Female 133 lb 4/13/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 1/1/2010 Female 7/22/2010 Consumer United States
Primary
Concomitant
Rash 1/1/2005 54 Female 7/29/2010 Consumer United States
Primary
Secondary
Concomitant
Tooth Disorder Hospitalization 1/1/2007 57 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 7/1/2010 81 Female 126 lb 9/15/2010 Consumer United States
Primary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Tooth Disorder Hospitalization 1/1/2007 57 Female 9/30/2010 Other Health Professional United States
Primary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Other Serious 2/27/2009 21 Female 190 lb 10/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Skin Disorder Other Serious 7/12/2010 66 Female 10/6/2010 Physician United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 9/4/2009 76 Female 179 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 1/1/2007 57 Female 10/14/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/31/2004 57 Female 181 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Skin Disorder Other Serious 7/12/2010 66 Female 11/30/2010 Physician United States
Primary
Concomitant
Metastatic Carcinoid Tumour Other Serious 9/10/2007 66 Female 193 lb 12/17/2010 Physician United States
Primary
Concomitant
Injection Site Reaction 12/19/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/19/2010 54 Female 157 lb 12/28/2010 Consumer Brazil
Primary
Concomitant
Wound Dehiscence Other Serious 9/19/2007 63 Female 133 lb 10/28/2010 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 8/1/2010 52 Female 1/10/2011 Other Health Professional Canada
Primary
Concomitant
Nausea Female 1/10/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/27/2009 20 Female 190 lb 1/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Injection Site Pain Hospitalization 2/1/2009 84 Female 204 lb 1/28/2011 Consumer United States
Primary
Concomitant
Eye Disorder Other Serious 3/1/2009 49 Male 1/29/2011 Physician United States
Primary
Concomitant
Injection Site Pain 5/1/2010 57 Female 1/29/2011 Consumer United States
Primary
Concomitant
Injection Site Erythema 6/17/2010 44 Female 1/29/2011 Consumer United States
Primary
Concomitant

Drug Data