Levothyroxine combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Hospitalization 12/24/2005 42 Female 1/6/2006 Other Health Professional Peru
Primary
Secondary
Concomitant
Sternal Fracture Hospitalization 5/10/2008 Female 121 lb 8/30/2008 Physician United States
Primary
Concomitant
Gastric Ulcer Perforation Hospitalization 7/27/2008 55 Female 141 lb 12/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/30/2008 Female 103 lb 12/29/2008 Consumer United States
Primary
Secondary
Concomitant
Tuberculin Test Positive Other Serious 11/1/2008 Female 170 lb 2/3/2009 Consumer Argentina
Primary
Concomitant
Pneumonia Hospitalization 11/1/2008 Female 2/3/2009 Brazil
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iv Other Serious 10/1/2008 Female 154 lb 2/6/2009 Consumer Chile
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Product Quality Issue 1/1/2006 46 Female 2/10/2009 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 3/2/2009 Female 190 lb 3/12/2009 Consumer Argentina
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 8/16/2008 Female 103 lb 3/17/2009 United States
Primary
Concomitant
Vaginal Fistula Other Serious 1/1/2008 Female 118 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Fistula Other Serious 1/1/2008 Female 118 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Death 11/17/2008 79 Female 106 lb 3/26/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/11/2002 Female 198 lb 3/27/2009 Physician Spain
Primary
Concomitant
Swelling 1/1/2009 Female 160 lb 6/11/2009 Other Health Professional
Primary
Concomitant
Pneumonia Hospitalization 10/1/2005 Female 150 lb 6/11/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection 10/1/2008 Female 165 lb 6/11/2009 United States
Primary
Concomitant
Trismus 1/1/2009 Female 215 lb 6/12/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection 12/1/2008 Female 250 lb 6/12/2009 United States
Primary
Concomitant
Joint Range Of Motion Decreased Female 250 lb 6/12/2009 Consumer United States
Primary
Concomitant
Drug Ineffective 3/1/2009 Female 122 lb 6/12/2009 United States
Primary
Concomitant
Injection Site Pain 4/4/2009 Female 130 lb 6/12/2009 United States
Primary
Concomitant
Drug Dose Omission 2/1/2009 Male 285 lb 6/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 5/1/2009 Female 152 lb 6/12/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma Male 190 lb 6/12/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 4/3/2009 Female 160 lb 6/12/2009 Consumer United States
Primary
Concomitant
Endocarditis Bacterial Life Threatening 3/15/2009 58 Female 108 lb 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 5/7/2009 Female 7/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/5/2009 68 Female 7/13/2009 Other Health Professional Argentina
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/6/2009 Female 196 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Disease Recurrence Hospitalization 3/4/2009 Male 243 lb 8/20/2009 Consumer United States
Primary
Concomitant
Rash 9/14/2008 Female 8/21/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 3/15/2009 58 Female 108 lb 8/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pharyngitis Other Serious 5/30/2006 38 Female 181 lb 8/26/2009 Other Health Professional Argentina
Primary
Concomitant
Knee Arthroplasty Other Serious 11/12/2008 Female 9/2/2009 Brazil
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/27/2008 93 Female 9/24/2009 United States
Primary
Concomitant
Dizziness Hospitalization 10/12/2009 56 Female 11/25/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Mycobacterium Chelonei Infection Other Serious 53 Female 262 lb 2/25/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Viral Hospitalization 2/27/2010 Female 191 lb 3/8/2010 Consumer United States
Primary
Concomitant
Polyserositis Other Serious 12/6/2009 52 Female 3/11/2010 Physician Argentina
Primary
Concomitant
Endometrial Cancer Life Threatening 5/29/2009 Female 201 lb 3/12/2010 United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 12/2/2005 47 Female 146 lb 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 6/15/2009 56 Female 4/16/2010 United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/21/2010 60 Male 267 lb 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 3/1/2009 50 Female 177 lb 4/16/2010 Physician United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 12/1/2009 49 Female 106 lb 4/19/2010 Consumer Argentina
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/14/2010 Female 159 lb 4/27/2010 Physician Chile
Primary
Secondary
Concomitant
Endometrial Cancer Life Threatening 5/29/2009 57 Female 201 lb 4/30/2010 United States
Primary
Concomitant
Liver Disorder Hospitalization 12/1/2009 49 Female 4/30/2010 Physician Argentina
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 12/1/2009 49 Female 106 lb 4/30/2010 Consumer Argentina
Primary
Concomitant
Pneumonia Other Serious 2/1/2010 66 Female 4/30/2010 Consumer United States
Primary
Concomitant
Epiglottitis Hospitalization 4/25/2010 71 Female 185 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 5/16/2010 52 Female 6/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting 6/22/2010 66 Female 130 lb 7/26/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Female 168 lb 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 3/1/2008 52 Female 110 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Cellulitis Hospitalization 4/9/2010 61 Female 159 lb 8/6/2010 Physician Chile
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 4/13/2010 72 Female 185 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting 6/22/2010 66 Female 130 lb 8/12/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 7/16/2010 46 Female 187 lb 8/13/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 7/7/2010 56 Female 121 lb 8/13/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/29/2008 55 Female 135 lb 8/13/2010 Physician Canada
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/1/2009 59 Female 199 lb 8/20/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 8/8/2010 47 Female 110 lb 9/2/2010 Consumer Peru
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 7/16/2010 46 Female 187 lb 9/2/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 1/1/2009 66 Female 162 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 55 Female 9/3/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/9/2010 40 Female 134 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/21/2010 70 Female 164 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Vertigo Other Serious 2/1/2010 45 Female 150 lb 9/13/2010 Physician United States
Primary
Concomitant
Nausea 6/7/2009 70 Female 9/15/2010 Consumer United States
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 6/9/2010 40 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 4/13/2010 72 Female 185 lb 9/20/2010 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 76 Female 150 lb 9/20/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2010 46 Female 250 lb 9/20/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 12/12/2009 76 Female 150 lb 9/20/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 9/19/2010 56 Female 270 lb 9/28/2010 Consumer Canada
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 9/19/2010 56 Female 270 lb 10/6/2010 Physician Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/1/2010 43 Male 258 lb 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Other Serious 7/21/2010 55 Female 179 lb 10/20/2010 Consumer United States
Primary
Concomitant
Ventricle Rupture Other Serious 1/1/2009 66 Female 163 lb 10/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Squamous Cell Carcinoma Metastatic Other Serious 3/17/2010 10/28/2010 Physician United Kingdom
Primary
Concomitant
Tongue Biting 71 Male 10/13/2010 Consumer United States
Primary
Concomitant
Tuberculosis Other Serious 1/1/1997 46 Female 11/4/2010 Physician Colombia
Primary
Secondary
Concomitant
Throat Tightness Other Serious 7/21/2010 55 Female 179 lb 11/12/2010 Consumer United States
Primary
Concomitant
Amenorrhoea Other Serious 11/1/2010 45 Female 11/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 11/10/2010 50 Female 137 lb 11/22/2010 Physician Argentina
Primary
Secondary
Concomitant
Pain In Extremity 11/18/2010 68 Female 148 lb 12/9/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2010 54 Female 132 lb 12/17/2010 Other Health Professional Brazil
Primary
Concomitant
Skin Discolouration 5/1/2010 50 Female 155 lb 11/6/2010 Other Health Professional United States
Primary
Concomitant
Arterial Thrombosis Hospitalization 7/9/2010 72 Female 141 lb 12/22/2010 Physician Netherlands
Primary
Concomitant
Radiation Injury Hospitalization 9 Female 12/14/2010 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2010 52 Female 159 lb 12/29/2010 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 11/25/2010 61 Male 170 lb 12/30/2010 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2008 68 Female 1/6/2011 Physician
Primary
Concomitant
Oral Pain Hospitalization 9/1/2010 53 Female 348 lb 9/20/2010 Pharmacist United States
Primary
Concomitant
Herpes Zoster Hospitalization 4/1/2010 64 Female 210 lb 1/13/2011 Consumer United States
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 11/24/2010 67 Female 216 lb 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 1/1/2008 65 Female 142 lb 2/18/2011 Physician
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2008 65 Female 142 lb 2/21/2011 Physician United States
Primary
Concomitant
Pulmonary Mass Hospitalization 2/1/2011 79 Female 2/21/2011 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 2/14/2011 79 Female 3/7/2011 Consumer United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 3/24/2009 58 Female 181 lb 3/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Bronchitis 49 Female 291 lb 3/14/2011 Consumer United States
Primary
Secondary
Concomitant
Mesangioproliferative Glomerulonephritis Hospitalization 1/1/2009 48 Female 254 lb 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Influenza Hospitalization 1/1/2007 47 Female 157 lb 3/16/2011 Consumer Brazil
Primary
Concomitant
Postoperative Wound Infection Hospitalization 8/13/2009 51 Female 276 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 3/31/2011 77 Female 145 lb 4/6/2011 Consumer United States
Primary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/5/2011 Physician United States
Primary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/27/2011 Physician United States
Primary
Concomitant
Osteoporosis Other Serious 1/1/2006 56 Male 207 lb 6/27/2011 Consumer United States
Primary
Concomitant
Cholecystectomy Hospitalization 8/1/2009 59 Male 207 lb 6/27/2011 Consumer United States
Primary
Concomitant
Flatulence 1/1/2011 61 Male 207 lb 6/27/2011 Consumer United States
Primary
Concomitant
Sinus Disorder 4/1/2008 58 Male 207 lb 6/29/2011 Consumer United States
Primary
Concomitant
Ethmoid Sinus Surgery Other Serious 1/1/2001 67 Female 7/13/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Abnormal Hospitalization 6/12/2011 55 Female 7/13/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/6/2011 74 Female 7/14/2011 Physician United Kingdom
Primary
Concomitant
Glossodynia Other Serious 7/1/2011 57 Female 155 lb 7/25/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 9/1/2011 55 Female 190 lb 9/30/2011 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious Female 110 lb 1/6/2012 Consumer United States
Primary
Secondary
Concomitant
Pain Female 245 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Female 247 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
Dysgeusia 4/1/2012 64 Female 156 lb 5/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oropharyngeal Cancer Stage Unspecified Hospitalization 4/30/2008 50 Female 103 lb 6/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 6/7/2012 54 Female 6/25/2012 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/5/2011 60 Female 187 lb 6/25/2012 Physician United Kingdom
Primary
Concomitant
Fibromyalgia 1/1/2012 40 Female 143 lb 6/26/2012 Consumer Brazil
Primary
Concomitant
Asthenia Other Serious 1/1/2000 76 Female 6/28/2012 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 1/1/2012 53 Female 211 lb 6/29/2012 Physician United States
Primary
Concomitant
Pelvic Mass Other Serious 1/1/2012 54 Female 6/29/2012 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin 4/13/2010 72 Female 185 lb 10/4/2012 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2008 Female 134 lb 11/15/2012 Physician Country Not Specified
Primary
Concomitant
Acute Sinusitis Hospitalization 10/10/2011 58 Female 203 lb 10/2/2012 Physician Us
Primary
Concomitant
Raynaud's Phenomenon Hospitalization 11/2005 Female 135 lb 9/19/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 12/31/2011 65 Female 122 lb 10/18/2012 Country Not Specified
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious 2008 50 Female 12/12/2012 Other Health Professional Co
Primary
Concomitant
Multiple Sclerosis Disability 2007 Male 146 lb 11/12/2012 Consumer Us
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2004 270 lb 9/15/2012 Consumer Country Not Specified
Primary
Concomitant
Pain Other Serious 8/2011 Female 175 lb 11/9/2012 Consumer Us
Primary
Concomitant
Urine Output Decreased Other Serious Female 143 lb 8/29/2012 Physician Country Not Specified
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 9/4/2012 Us
Primary
Concomitant
Vomiting Other Serious 2009 Female 112 lb 9/8/2012 Consumer Us
Primary
Secondary
Concomitant
Rheumatoid Lung Hospitalization 6/18/2012 85 Female 123 lb 9/18/2012 Physician Country Not Specified
Primary
Concomitant

Drug Data