Diazepam combined with Methotrexate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lumbar Spinal Stenosis Other Serious 5/19/2005 Female 119 lb 2/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 1/4/2006 Male 2/7/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Female 2/9/2006 United Kingdom
Primary
Concomitant
Therapy Non-responder Other Serious 9 Male 2/6/2006
Primary
Secondary
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/18/2006 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 119 lb 4/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/30/2006 Male 119 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 115 lb 6/2/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/29/2006 Male 115 lb 6/2/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 6/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 6/28/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/4/2006 74 Female 7/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 1/4/2006 Male 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lung Infiltration Hospitalization 1/27/2006 Female 8/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Spinal Disorder Hospitalization Male 210 lb 8/30/2006 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/22/2006 Female 9/8/2006 Physician United States
Primary
Concomitant
Injection Site Pain 5/1/2006 Female 12/20/2006 Pharmacist United States
Primary
Concomitant
Muscle Spasms Other Serious Female 211 lb 12/27/2006 Consumer United States
Primary
Concomitant
Panic Attack Other Serious Female 211 lb 1/26/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/11/2006 68 Female 2/9/2007 Brazil
Primary
Secondary
Concomitant
Dyspnoea Disability 12/1/2006 78 Female 2/13/2007 United States
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/26/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/11/2006 68 Female 2/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 119 lb 3/20/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Palpitations 54 Female 196 lb 3/27/2007 Consumer United States
Primary
Concomitant
Photophobia Other Serious 6/1/2006 Female 252 lb 4/5/2007 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 1/1/1999 Female 141 lb 5/18/2007 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/4/2006 79 Female 150 lb 5/23/2007 Other Health Professional United States
Primary
Concomitant
Palpitations 2/23/2007 54 Female 196 lb 6/25/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 7/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 7/19/2007 Male 148 lb 8/3/2007 Canada
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 7/19/2007 Male 148 lb 9/5/2007 Canada
Primary
Concomitant
Psychotic Disorder Hospitalization 7/21/2006 Male 159 lb 9/6/2007 United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 3/1/2007 Female 118 lb 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Clavicle Fracture Hospitalization 12/21/2006 Male 130 lb 9/14/2007 United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 45 Female 154 lb 10/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sensation Of Pressure Other Serious 9/4/2007 Male 10/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/4/2005 Male 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Other Serious 10/18/2007 Male 148 lb 11/9/2007 Canada
Primary
Concomitant
Drug Dependence Death 10/6/2007 40 Female 198 lb 11/13/2007 Consumer United States
Primary
Concomitant
Sensation Of Pressure Other Serious 9/4/2007 Male 11/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death Male 152 lb 11/26/2007 United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 144 lb 12/6/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/18/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 12/27/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/10/2002 43 Female 351 lb 1/21/2008 Physician United States
Primary
Concomitant
Sensory Disturbance Other Serious 12/1/2007 Female 109 lb 2/7/2008 Physician United Kingdom
Primary
Concomitant
Infusion Related Reaction 3/12/2007 Female 97 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 12/1/2007 Female 109 lb 2/14/2008 Physician United Kingdom
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 2/29/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2007 Female 170 lb 3/5/2008 United States
Primary
Concomitant
Tuberculosis Other Serious 7/19/2004 Female 163 lb 3/5/2008 United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 45 Female 154 lb 3/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Other Serious 3/20/2007 Female 168 lb 3/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumothorax Other Serious 5/31/2006 54 Male 123 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Sensation Of Pressure Other Serious 9/4/2007 Male 5/21/2008 United Kingdom
Primary
Concomitant
Influenza 2/1/2008 Female 234 lb 6/12/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 3/1/2008 Female 138 lb 6/13/2008 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 5/11/2008 Female 199 lb 6/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 5/24/2007 Female 174 lb 6/27/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 5/11/2008 61 Female 199 lb 7/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 5/27/2008 Male 190 lb 7/28/2008 United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 144 lb 8/4/2008 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 8/8/2007 Female 143 lb 8/12/2008 Physician United States
Primary
Concomitant
Myocardial Ischaemia Death 3/28/2008 Female 163 lb 8/13/2008 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/8/2008 71 Male 8/15/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 8/15/2008 Other Health Professional Brazil
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 6/4/2007 Female 8/27/2008 Physician Sweden
Primary
Concomitant
Nasopharyngitis 2/1/2008 Female 236 lb 9/12/2008 United States
Primary
Concomitant
Rheumatoid Arthritis Death Male 152 lb 9/19/2008 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Death Male 152 lb 9/29/2008 United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious Male 250 lb 10/13/2008 Canada
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 10/16/2008 Other Health Professional Brazil
Primary
Concomitant
Rheumatic Heart Disease Death 7/9/2008 Female 143 lb 10/23/2008 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 5/16/2008 Female 166 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Sputum Discoloured Hospitalization 3/1/2007 63 Male 12/4/2008 Other Health Professional Spain
Primary
Concomitant
Stress 3/1/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/27/2008 Male 190 lb 12/12/2008 United States
Primary
Concomitant
Sinusitis 12/1/2007 Female 12/12/2008 Physician United States
Primary
Concomitant
Oedema Peripheral 11/3/2008 Female 156 lb 12/12/2008 Consumer United States
Primary
Concomitant
Latex Allergy Female 12/13/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 6/30/2008 Female 170 lb 1/12/2009 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/30/2008 Female 155 lb 1/23/2009 United Kingdom
Primary
Concomitant
Carpal Tunnel Syndrome Other Serious 11/1/2008 Female 125 lb 1/27/2009 Physician United States
Primary
Concomitant
Rheumatic Heart Disease Death 7/9/2008 Female 143 lb 2/5/2009 United Kingdom
Primary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/1999 52 Female 3/2/2009 Physician United States
Primary
Concomitant
Depression Hospitalization 1/1/2009 Male 117 lb 3/6/2009 Brazil
Primary
Concomitant
Injection Site Haemorrhage 1/6/2009 Female 140 lb 3/14/2009 United States
Primary
Concomitant
Nail Dystrophy Disability 1/1/2007 70 Female 161 lb 3/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Anaphylactic Reaction Life Threatening 12/1/2008 Female 4/16/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Arrest Life Threatening 5 Male 5/14/2009
Primary
Secondary
Concomitant
Respiratory Tract Congestion 4/1/2009 Female 6/12/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/16/2006 59 Female 140 lb 6/16/2009 United States
Primary
Concomitant
Endocarditis Bacterial Life Threatening 3/15/2009 58 Female 108 lb 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Bacterial Female 269 lb 4/13/2009 United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Disability 6/14/2009 60 7/24/2009 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 8/1/2008 Female 240 lb 7/30/2009 United States
Primary
Concomitant
Myocardial Ischaemia Death Male 130 lb 8/11/2009 United Kingdom
Primary
Concomitant
Histoplasmosis Disseminated Other Serious 5/7/2008 Male 226 lb 8/13/2009 Physician United States
Primary
Concomitant
Mitral Valve Incompetence Other Serious 1/1/2007 Male 194 lb 8/21/2009 Brazil
Primary
Concomitant
Lung Adenocarcinoma Metastatic Death Male 128 lb 8/26/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 3/15/2009 58 Female 108 lb 8/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/1/2009 Poland
Primary
Secondary
Concomitant
Dysarthria Hospitalization 4/12/2009 Female 110 lb 9/8/2009 Netherlands
Primary
Concomitant
Injection Site Extravasation 3/1/2008 Female 138 lb 9/12/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 3/2/2009 58 Female 108 lb 9/18/2009 Physician United Kingdom
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 6/16/2009 Male 265 lb 9/19/2009 Consumer United States
Primary
Concomitant
Tremor Other Serious 9/9/2009 65 Female 9/21/2009 Pharmacist Portugal
Primary
Concomitant
Grand Mal Convulsion Life Threatening 7/5/2008 14 Male 101 lb 9/14/2009 Physician Poland
Primary
Secondary
Concomitant
Overdose Life Threatening 7/5/2008 14 Male 101 lb 9/21/2009 Physician Poland
Primary
Secondary
Concomitant
Tremor Other Serious 9/9/2009 65 Female 10/28/2009 Pharmacist Portugal
Primary
Concomitant
Tremor Other Serious 9/9/2009 65 Female 11/2/2009 Pharmacist Portugal
Primary
Concomitant
Tendon Rupture Hospitalization 2/24/2009 Female 110 lb 11/2/2009 Japan
Primary
Concomitant
Tremor Other Serious 9/9/2009 Female 11/4/2009 Pharmacist Portugal
Primary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 11/4/2009 Physician Argentina
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 11/5/2009 Physician Argentina
Primary
Secondary
Concomitant
Convulsion Other Serious 7 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 9/4/2007 Male 11/18/2009 United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/4/2007 Male 11/19/2009 United Kingdom
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 6/2/2008 59 Female 132 lb 11/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 6/2/2008 Female 132 lb 11/20/2009 Physician United Kingdom
Primary
Concomitant
Latex Allergy Female 12/3/2009 Pharmacist
Primary
Concomitant
Extrapulmonary Tuberculosis Other Serious 7/19/2004 Female 163 lb 12/11/2009 United Kingdom
Primary
Concomitant
Claustrophobia Other Serious 68 Male 12/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Other Serious Female 132 lb 12/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 7 Female 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 62 Female 1/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mouth Haemorrhage Life Threatening 12/31/2009 40 Female 1/15/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/17/2009 62 Female 142 lb 1/21/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 1/25/2010 Physician Argentina
Primary
Secondary
Concomitant
Overdose Hospitalization 62 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 1/31/2010 Physician Argentina
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/22/2010 United Kingdom
Primary
Secondary
Concomitant
Spindle Cell Sarcoma Life Threatening 3/13/2008 Female 328 lb 2/17/2010 Physician Australia
Primary
Secondary
Concomitant
Oedema Peripheral 7/1/2009 48 Female 154 lb 2/22/2010 Consumer United States
Primary
Concomitant
Spindle Cell Sarcoma Life Threatening 3/13/2008 Female 328 lb 3/12/2010 Physician Australia
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 Female 150 lb 3/14/2010 Physician Argentina
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/29/2009 Female 3/15/2010 Czech Republic
Primary
Concomitant
Proctitis Hospitalization 8/1/2009 Male 150 lb 3/24/2010 Brazil
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 69 Male 3/30/2010 Physician United States
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 10/15/2009 44 Female 150 lb 4/5/2010 Physician Argentina
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 69 Male 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 1/12/2010 53 Female 152 lb 4/21/2010 United Kingdom
Primary
Concomitant
Vulvovaginal Human Papilloma Virus Infection Other Serious 1/1/2009 61 Female 161 lb 4/21/2010 Brazil
Primary
Concomitant

Drug Data