Methotrexate combined with Nifedipine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Amyotrophic Lateral Sclerosis Hospitalization 3/1/2005 46 Male 1/16/2006 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/1/2005 46 Male 1/26/2006 Physician Spain
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Coronary Artery Disease Death Female 3/1/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 3/1/2001 Female 4/4/2006 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 2/1/2006 Female 180 lb 4/7/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/31/2006 Female 225 lb 4/13/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/31/2006 Female 225 lb 5/11/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2003 37 Female 6/28/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2003 37 Female 6/22/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Death 8/1/2005 Male 230 lb 7/10/2006 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 12/1/2005 Male 7/10/2006 Physician United States
Primary
Concomitant
Death Other Serious Male 119 lb 7/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 5/31/2005 Male 119 lb 7/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 5/19/2005 Male 119 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 1/10/2006 Female 157 lb 8/14/2006 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 8/9/2006 68 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 8/9/2006 68 Female 8/24/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 8/9/2006 68 Female 8/23/2006 Pharmacist United States
Primary
Concomitant
Diverticulitis Hospitalization 12/19/2005 Male 9/6/2006 Physician United States
Primary
Concomitant
Thalamic Infarction Hospitalization 11/29/2005 53 Female 159 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Appendicectomy Hospitalization 3/20/2004 Female 157 lb 9/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious Female 9/26/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Male 9/26/2006 Physician United States
Primary
Concomitant
Pyelonephritis Acute Other Serious 10/23/2006 46 Female 11/1/2006 Other Health Professional Thailand
Primary
Concomitant
Respiratory Rate Increased Other Serious 10/23/2006 46 Female 11/13/2006 Other Health Professional Thailand
Primary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Prostate Cancer Hospitalization 4/1/2006 Male 12/8/2006 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Injection Site Reaction 7/24/2006 Female 12/18/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 2/1/2006 Female 180 lb 12/21/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2006 Female 128 lb 8/17/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious 7/5/2006 152 lb 1/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 152 lb 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Fibrosis Hospitalization 66 Female 2/26/2007
Primary
Secondary
Concomitant
Retroperitoneal Fibrosis Hospitalization 1/1/2006 66 Female 4/11/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2005 73 Female 4/20/2007 Physician Greece
Primary
Concomitant
Yellow Skin Other Serious 10/1/2006 Male 154 lb 5/3/2007 Consumer Brazil
Primary
Concomitant
Pyrexia Hospitalization 4/8/2007 59 Female 5/7/2007 Other Health Professional Mexico
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/16/2006 Female 123 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Penile Pain Hospitalization 12/28/2004 Male 6/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/28/2004 Male 6/11/2007 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/28/2004 Male 6/16/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 1/1/2005 Male 119 lb 6/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bowen's Disease Other Serious 6/1/2005 83 Female 7/5/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Ureteric Obstruction Other Serious 10/1/2004 Female 7/13/2007 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 7/5/2006 Male 152 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Life Threatening 44 Female 7/18/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious 33 Female 8/1/2007 Korea, Republic Of
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/29/2007 Female 180 lb 11/12/2007 United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9 Male 11/21/2007 Sweden
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 10/5/2007 69 Male 225 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 10/5/2007 69 Male 225 lb 11/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Back Disorder Hospitalization 9/15/2007 Female 229 lb 12/6/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/5/2006 9 Female 41 lb 11/30/2007 United Kingdom
Primary
Secondary
Concomitant
Neoplasm Other Serious 6/8/2007 Male 143 lb 12/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection 9/13/2007 Female 147 lb 12/14/2007 Physician United States
Primary
Concomitant
Injection Site Irritation 7/26/2007 Male 326 lb 12/14/2007 Consumer United States
Primary
Concomitant
Injection Site Pain 9/1/2007 Female 127 lb 12/14/2007 Consumer United States
Primary
Concomitant
Bowen's Disease Other Serious 4/1/2007 83 Female 12/17/2007 Other Health Professional United States
Primary
Concomitant
Abdominal Wall Abscess Hospitalization 3/29/2007 Female 134 lb 12/28/2007 United Kingdom
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 6/8/2007 66 Male 143 lb 1/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious 6/1/2006 Female 1/17/2008 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/1/2007 9 Male 1/16/2008 Sweden
Primary
Secondary
Concomitant
Bowen's Disease Other Serious 4/1/2007 85 Female 2/5/2008 Other Health Professional United States
Primary
Concomitant
Rash Papular Other Serious 52 Female 2/21/2008
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/14/2008 81 Female 150 lb 2/22/2008 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/15/2007 Female 165 lb 2/26/2008 Physician United Kingdom
Primary
Concomitant
Cardiac Disorder Hospitalization 8/15/2007 Female 165 lb 2/27/2008 Physician United Kingdom
Primary
Concomitant
Skin Laceration 11/24/2007 Female 155 lb 3/14/2008 United States
Primary
Concomitant
Respiratory Tract Congestion 12/17/2007 Female 184 lb 3/14/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 69 Male 4/18/2008 United Kingdom
Primary
Secondary
Concomitant
Tonsillitis Other Serious 3/1/2005 74 Female 6/6/2008 Greece
Primary
Concomitant
Post Procedural Infection Hospitalization 8/15/2007 Female 165 lb 6/11/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious Female 6/11/2008 Physician Australia
Primary
Concomitant
Pancreatitis Acute Other Serious 3/19/2005 79 Female 98 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tonsillitis Other Serious 3/1/2005 74 Female 6/19/2008 Greece
Primary
Concomitant
Hernia Other Serious 3/12/2008 Female 165 lb 7/3/2008 United States
Primary
Concomitant
Pulmonary Mass Hospitalization 7/4/2008 Female 161 lb 8/1/2008 China
Primary
Concomitant
Metastases To Liver Other Serious 3/28/2008 Female 123 lb 8/7/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Mass Hospitalization 7/4/2008 Female 157 lb 8/14/2008 China
Primary
Concomitant
Pulmonary Mass Hospitalization 7/4/2008 Female 157 lb 9/5/2008 China
Primary
Concomitant
Hypoaesthesia Hospitalization 6/1/2003 44 Female 181 lb 9/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Bronchiectasis Hospitalization 10/1/2008 55 Female 10/14/2008 Consumer Thailand
Primary
Concomitant
Pulmonary Fibrosis Death 5/31/2008 Female 123 lb 10/23/2008 United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/1/2008 Female 11/14/2008 Netherlands
Primary
Concomitant
Sepsis Other Serious 1/1/2008 Female 12/4/2008 Netherlands
Primary
Concomitant
Pain Hospitalization Female 12/8/2008 Brazil
Primary
Concomitant
Injection Site Pain Male 183 lb 12/12/2008 Consumer United States
Primary
Concomitant
Thrombosis 8/1/2008 Female 145 lb 12/12/2008 Consumer United States
Primary
Concomitant
Injection Site Irritation 11/18/2008 Male 178 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Fibrosis Death 5/31/2008 Female 123 lb 12/23/2008 United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 4/9/2008 Male 12/31/2008 Physician United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization Female 1/26/2009 Brazil
Primary
Concomitant
Death Hospitalization 9/15/2008 Male 1/27/2009 Physician United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/16/2008 Male 1/30/2009 Physician United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization 1/1/2007 Female 2/6/2009 Brazil
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 11/21/2005 Female 132 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Localised Infection 9/1/2008 Male 198 lb 3/14/2009 United States
Primary
Concomitant
Rash 1/1/2008 Female 210 lb 3/14/2009 Physician United States
Primary
Concomitant
Pulmonary Mass Hospitalization 7/4/2008 Female 157 lb 5/8/2009 China
Primary
Concomitant
Interstitial Lung Disease Life Threatening 3/10/2009 Female 111 lb 6/1/2009 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/10/2009 Female 6/10/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 3/10/2009 Female 111 lb 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 5/15/2009 Female 154 lb 6/22/2009 Physician Netherlands
Primary
Concomitant
Weight Decreased Other Serious 3/1/2004 75 Female 7/2/2009
Primary
Secondary
Concomitant
Underdose Other Serious 7/1/2006 66 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypoglycaemia Death 6/15/2006 19 Male 130 lb 7/22/2009 United States
Primary
Concomitant
Stomatitis Hospitalization 7/15/2009 72 Female 114 lb 8/17/2009 Japan
Primary
Concomitant
Blood Glucose Increased 4/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Muscle Spasms 9/13/2006 Female 241 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 9/1/2007 Female 127 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain Male 183 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 98 lb 9/25/2009 Japan
Primary
Concomitant
Stomatitis Hospitalization 7/15/2009 72 Female 114 lb 9/22/2009 Physician Japan
Primary
Concomitant
Acoustic Neuroma Other Serious 1/1/2005 62 Female 10/2/2009 Consumer Netherlands
Primary
Concomitant
Pain Other Serious Female 154 lb 10/15/2009 Brazil
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 98 lb 10/19/2009 Japan
Primary
Concomitant
Acoustic Neuroma Other Serious 1/1/2006 61 Female 10/27/2009 Physician Netherlands
Primary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Lung Infection Hospitalization 8/1/2009 Female 150 lb 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Male 200 lb 12/1/2009 Consumer United States
Primary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 98 lb 12/3/2009 Japan
Primary
Concomitant
No Adverse Event Female 145 lb 12/1/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/30/2007 25 Female 130 lb 11/9/2009 Lawyer United States
Primary
Concomitant
Herpes Zoster Hospitalization 5/6/2008 Male 110 lb 12/30/2009 Japan
Primary
Secondary
Concomitant
Vasculitis Hospitalization 2/1/2009 Female 98 lb 12/30/2009 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
Vasculitis Other Serious 2/1/2009 Female 98 lb 1/29/2010 Japan
Primary
Secondary
Concomitant
Lung Infection Other Serious Female 163 lb 2/15/2010 Brazil
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Swelling Other Serious Male 198 lb 3/5/2010 Brazil
Primary
Concomitant
Vomiting Hospitalization 12/18/2009 Female 3/10/2010 Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/13/2010 Female 78 lb 3/18/2010 Brazil
Primary
Concomitant
Pain Other Serious 1/30/2010 Female 154 lb 3/22/2010 Brazil
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 7/15/2009 66 Female 139 lb 4/9/2010 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 4/7/2010 Japan
Primary
Secondary
Concomitant
Lung Infection Other Serious 12/1/2009 61 Female 163 lb 4/13/2010 Brazil
Primary
Concomitant
Skin Discolouration Other Serious 3/1/2010 56 Female 132 lb 4/16/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Disability 6/1/2007 70 Female 219 lb 4/15/2010 United States
Primary
Concomitant

Drug Data