Methotrexate combined with Voltaren

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Life Threatening 6/30/2005 Female 99 lb 1/6/2006 Physician Japan
Primary
Concomitant
Swelling Face Disability 12/9/2005 Male 1/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 9/1/2004 Male 176 lb 2/6/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 10/7/2004 Female 112 lb 2/10/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 6/29/2005 Male 161 lb 2/10/2006 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/19/2005 Female 90 lb 2/17/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/9/2005 47 Male 2/23/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/18/2006 Female 117 lb 2/24/2006 Physician Japan
Primary
Secondary
Urinary Tract Infection Life Threatening 1/11/2006 77 Female 2/24/2006 Physician France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 4/1/2005 Female 126 lb 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/8/2003 Male 3/1/2006 Other Health Professional Norway
Primary
Secondary
Concomitant
Chest X-ray Abnormal Other Serious 11/16/2005 Female 95 lb 3/7/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Hospitalization 9/1/2004 Male 176 lb 3/9/2006 Physician Japan
Primary
Concomitant
Spondylolisthesis Hospitalization 10/29/2005 Female 3/14/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 3/11/2005 Female 110 lb 3/17/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/12/2003 Female 126 lb 3/23/2006 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Other Serious 12/15/2005 Female 203 lb 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 7/19/2005 Female 90 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/3/2004 30 Female 99 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/29/2005 Female 5/12/2006 Physician Japan
Primary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 5/17/2006 Physician Japan
Primary
Secondary
Concomitant
Guillain-barre Syndrome Disability 5/10/2005 Female 5/18/2006 Physician United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 3/14/2005 Male 121 lb 5/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2006 65 Female 5/30/2006 Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/29/2005 Female 6/15/2006 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 57 Female 6/8/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2006 65 Female 6/12/2006 Physician Italy
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/19/2005 Female 148 lb 6/29/2006 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 12/17/2003 Female 117 lb 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 6/13/2006 33 Female 214 lb 6/28/2006 Other Health Professional United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/22/2005 Female 121 lb 7/7/2006 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/12/2003 Female 126 lb 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 7/31/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/18/2006 Female 117 lb 8/1/2006 Physician Japan
Primary
Secondary
Thymoma Malignant Other Serious 5/1/2005 Female 8/4/2006 Physician United Kingdom
Primary
Concomitant
Thymoma Malignant Other Serious 5/1/2005 Female 8/4/2006 Physician United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 7/20/2006 37 Female 8/7/2006 Physician Germany
Primary
Concomitant
Sinus Tachycardia Hospitalization 6/13/2006 33 Female 214 lb 8/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/13/2006 33 Female 214 lb 8/3/2006 Physician United States
Primary
Concomitant
Melanocytic Naevus Other Serious 9/15/2004 Female 141 lb 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thymoma Other Serious 5/14/2006 Female 140 lb 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 Female 132 lb 8/17/2006 Physician Germany
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 8/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/23/2006 Female 82 lb 8/28/2006 Physician Japan
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 12/17/2003 Female 117 lb 9/6/2006 Physician Japan
Primary
Secondary
Concomitant
Peritoneal Tuberculosis Other Serious 12/26/2003 Female 9/14/2006 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 6/23/2006 Female 82 lb 9/27/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Death 9/1/2005 37 Female 141 lb 9/28/2006 Physician France
Primary
Concomitant
Osteoarthritis Hospitalization Female 10/4/2006 Physician United States
Primary
Concomitant
Breast Cancer Female Hospitalization Female 10/6/2006 Pharmacist Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/6/2005 38 Female 10/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 10/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Reaction Hospitalization 11/6/2005 38 Female 10/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/5/2004 47 Female 11/6/2006 Physician Japan
Primary
Concomitant
Temporal Lobe Epilepsy Hospitalization 9/13/2005 31 Female 10/30/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neck Pain Hospitalization 8/19/2006 Male 11/29/2006 Physician Japan
Primary
Concomitant
Arthritis Infective Hospitalization 6/21/2006 55 Female 11/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 5/11/2006 Female 12/5/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/1/2005 Female 12/11/2006 Physician United States
Primary
Concomitant
Mediastinal Abscess Hospitalization 9/27/2006 Male 12/12/2006 Physician Japan
Primary
Concomitant
Hodgkin's Disease Other Serious 9/4/2006 Female 126 lb 12/13/2006 Physician Japan
Primary
Secondary
Concomitant
Stenotrophomonas Infection Hospitalization 9/30/2006 Female 154 lb 12/21/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/5/2004 47 Female 12/22/2006 Physician Japan
Primary
Concomitant
Haemorrhage Hospitalization 11/6/2006 Female 90 lb 12/28/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/22/2005 Female 121 lb 1/4/2007 Physician Japan
Primary
Secondary
Concomitant
Diverticular Perforation Hospitalization 11/13/2006 Male 1/4/2007 Physician Belgium
Primary
Concomitant
Myocardial Infarction Life Threatening 3/12/2004 57 Female 137 lb 12/29/2006 Physician France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/3/2005 71 Female 88 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 2/22/2006 Female 128 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Diverticulitis Death Female 1/25/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 4/19/2004 Female 1/29/2007 Physician Sweden
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 11/6/2006 Female 90 lb 1/30/2007 Physician Japan
Primary
Concomitant
Peritonitis Other Serious 10/15/2006 Male 152 lb 2/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Column Stenosis Other Serious 11/1/2005 Female 183 lb 2/2/2007 Physician United States
Primary
Concomitant
Sepsis Other Serious 2/22/2006 Female 128 lb 2/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 11/28/2006 72 Female 2/9/2007 France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2005 Female 183 lb 2/14/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/3/2005 71 Female 88 lb 2/1/2007 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Other Serious 7/28/2004 Female 134 lb 2/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 4/26/2006 Female 2/28/2007 Other Health Professional Canada
Primary
Concomitant
Sepsis Other Serious 2/22/2006 40 Female 128 lb 3/7/2007 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 2/22/2006 40 Female 128 lb 3/8/2007 United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 8/19/2005 Female 168 lb 3/20/2007 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 2/19/2007 Male 3/22/2007 Physician Japan
Primary
Concomitant
Stress Other Serious 12/21/2006 80 Female 81 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/1/2007 Female 108 lb 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pericarditis Hospitalization 7/1/2006 53 Male 4/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Oesophageal Carcinoma Other Serious 3/22/2006 Male 192 lb 4/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/1/2007 Female 108 lb 4/12/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 4/12/2007 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 3/30/2007 Female 117 lb 4/16/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 4/18/2007 Physician Japan
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 2/22/2007 Male 190 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 3/16/2007 Female 108 lb 4/20/2007 Physician Japan
Primary
Concomitant
Oesophageal Carcinoma Other Serious 3/22/2006 Male 192 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumothorax Hospitalization 3/16/2007 Female 108 lb 5/1/2007 Physician Japan
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 1/1/2007 Female 132 lb 5/7/2007 Physician Japan
Primary
Secondary
Concomitant
Diverticular Perforation Hospitalization 11/13/2006 Male 5/7/2007 Physician Belgium
Primary
Concomitant
Food Poisoning Other Serious 4/1/2007 Female 117 lb 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Hospitalization 1/1/2006 Female 183 lb 5/10/2007 Physician United Kingdom
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 1/1/2007 Female 132 lb 5/14/2007 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/16/2007 Female 108 lb 5/22/2007 Physician Japan
Primary
Concomitant
Diverticular Perforation Hospitalization 11/13/2006 Male 5/22/2007 Physician Belgium
Primary
Concomitant
Medical Device Removal Other Serious 8/1/2006 Female 143 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Uterine Cancer Other Serious 3/30/2007 Female 117 lb 5/25/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2004 Male 121 lb 6/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/16/2007 Female 108 lb 6/5/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2/1/2007 Female 132 lb 6/5/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 6/18/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 6/12/2007 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 2/21/2007 Female 165 lb 6/20/2007 Physician Germany
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 3/30/2007 Female 117 lb 6/21/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 6/21/2007 Physician Japan
Primary
Secondary
Concomitant
Stress Other Serious 12/21/2006 80 Female 81 lb 6/11/2007 Physician Japan
Primary
Secondary
Vomiting Hospitalization 7/22/2004 Male 121 lb 7/6/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/21/2007 Female 165 lb 7/9/2007 Physician Germany
Primary
Secondary
Concomitant
Neuralgia Other Serious 7/1/2006 Female 148 lb 7/17/2007 Consumer United States
Primary
Concomitant
Dislocation Of Joint Prosthesis Other Serious 7/31/2006 Female 187 lb 7/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12/12/2003 Female 126 lb 7/19/2007 Physician Japan
Primary
Secondary
Concomitant
Tremor Other Serious 5/18/2007 57 Female 150 lb 7/20/2007 Physician France
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 7/30/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 2/1/2007 Female 132 lb 8/1/2007 Physician Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 6/4/2006 Female 79 lb 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Required Intervention 10/21/2003 58 Female 118 lb 7/5/2007 United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 7/19/2006 Male 8/2/2007 Physician Germany
Primary
Secondary
Concomitant
Aortic Dissection Death 5/11/2006 Female 110 lb 8/6/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/25/2005 Female 66 lb 8/7/2007 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 2/21/2007 56 Female 8/18/2007 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/4/2007 Female 122 lb 8/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Glioblastoma Multiforme Other Serious 5/15/2006 Male 179 lb 8/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization Female 132 lb 8/30/2007 Canada
Primary
Concomitant
Lymphoma Life Threatening 5/19/2006 Male 10/19/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2007 58 Female 10/23/2007 Consumer United States
Primary
Secondary
Concomitant
Appendicitis Perforated Hospitalization 4/1/2007 Female 198 lb 10/22/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2007 75 Male 11/10/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/15/2007 Female 112 lb 11/12/2007 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 7/1/2007 Male 11/13/2007 Physician Norway
Primary
Secondary
Concomitant
Lymphoma Life Threatening 5/19/2006 Male 11/14/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 8/15/2007 Male 161 lb 11/21/2007 Physician Canada
Primary
Concomitant
Hypersomnia Other Serious 10/4/2007 44 Male 192 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin D Deficiency Other Serious 7/1/2005 Female 181 lb 12/3/2007 Physician United States
Primary
Concomitant
Tooth Infection Hospitalization 6/1/2001 Female 170 lb 12/6/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2006 Female 148 lb 12/7/2007 Other Health Professional United States
Primary
Concomitant
Swelling Female 12/12/2007 Consumer United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 7/1/2005 Female 181 lb 12/18/2007 Physician United States
Primary
Concomitant

Drug Data