Methotrexate combined with Novolog

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 3/1/2005 Female 6/23/2006 Physician United States
Primary
Concomitant
Necrotising Fasciitis Hospitalization 4/28/2007 Female 117 lb 6/27/2007 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 8/6/2007 Female 8/23/2007 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness 10/16/2007 Female 114 lb 10/22/2007 United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/6/2007 54 Female 150 lb 11/9/2007 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 8/6/2007 54 Female 150 lb 11/20/2007 United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Hospitalization 10/1/2005 Female 206 lb 12/6/2007 Physician United States
Primary
Concomitant
Myalgia Other Serious 2/28/2007 60 Female 114 lb 4/27/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 9/13/2007 Female 119 lb 12/10/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Procedural Complication 11/30/2007 Female 180 lb 3/14/2008 Consumer United States
Primary
Concomitant
Sinusitis 3/19/2008 Female 180 lb 6/12/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Rash 5/15/2008 58 Female 226 lb 7/30/2008 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 Male 8/12/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/5/2008 27 Male 163 lb 11/25/2008 Physician United States
Primary
Secondary
Pyrexia Hospitalization 6/5/2008 27 Male 162 lb 11/26/2008 Physician United States
Primary
Secondary
Withdrawal Syndrome Hospitalization 6/25/2008 27 Male 162 lb 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 6/25/2008 27 Male 162 lb 12/10/2008 United States
Primary
Secondary
Hypoglycaemic Unconsciousness Required Intervention 2/18/2008 74 Female 11/21/2008 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 2/19/2009 68 Female 141 lb 3/3/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/24/2007 39 Male 176 lb 5/4/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Venous Insufficiency Hospitalization 82 Male 10/23/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/4/2009 Lawyer United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 82 Male 11/17/2009 United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 12/23/2009 Other Health Professional United States
Primary
Concomitant
Pain 10/13/2009 Male 244 lb 1/30/2010 United States
Primary
Concomitant
Sinusitis 8/1/2009 Male 155 lb 1/30/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 10/1/2007 Male 210 lb 2/10/2010 United States
Primary
Concomitant
Death Death Male 190 lb 2/15/2010 Consumer United States
Primary
Concomitant
Cholecystitis Hospitalization 1/24/2010 Female 2/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2010 83 Male 156 lb 4/23/2010 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Death Male 190 lb 5/6/2010 Physician United States
Primary
Concomitant
Bone Disorder Other Serious 1/1/2006 61 Female 129 lb 5/18/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2010 83 Male 156 lb 6/15/2010 Physician United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 11/28/2009 59 Female 335 lb 6/18/2010 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 1/21/2010 68 Male 138 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 11/28/2009 59 Female 335 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus 1/1/2009 31 Female 186 lb 9/14/2010 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 1/1/2010 67 Female 174 lb 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Hospitalization 2/1/2010 67 Female 174 lb 11/9/2010 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Hospitalization 1/1/2010 67 Female 174 lb 11/23/2010 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 4/1/2010 11/23/2010 Consumer United States
Primary
Concomitant
Nausea Other Serious 4/1/2010 11/27/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 9/11/2009 11/30/2010 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 2/1/2010 67 Female 174 lb 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 4/1/2010 12/10/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious Male 1/18/2011 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2010 64 Male 1/26/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2010 70 Female 200 lb 1/29/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Male 188 lb 1/30/2011 Consumer United States
Primary
Concomitant
Contusion 11/2/2010 58 Female 310 lb 1/30/2011 Consumer United States
Primary
Concomitant
Headache 9/18/2010 59 Female 1/30/2011 Consumer United States
Primary
Concomitant
Cough 10/22/2010 67 Female 140 lb 1/30/2011 Consumer United States
Primary
Concomitant
Depression 10/1/2010 74 Female 185 lb 1/30/2011 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 1/1/2010 64 Male 245 lb 4/21/2011 Consumer United States
Primary
Concomitant
Myositis Hospitalization 1/1/2003 44 Female 189 lb 4/21/2011 Lawyer United States
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 6/12/2011 55 Female 6/22/2011 Consumer United States
Primary
Concomitant
Pancytopenia Death 1/1/2011 45 Male 400 lb 7/8/2011 Consumer United States
Primary
Concomitant
Blood Glucose Abnormal Hospitalization 6/12/2011 55 Female 7/13/2011 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Hospitalization 1/1/2011 45 Male 400 lb 7/19/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2011 45 Male 400 lb 8/3/2011 Physician United States
Primary
Concomitant
Grip Strength Decreased Hospitalization 6/1/2011 63 Female 8/9/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 4/1/2010 8/19/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 4/1/2010 8/21/2011 Consumer United States
Primary
Concomitant
Weight Decreased Death 1/1/2011 45 Male 287 lb 8/26/2011 Physician United States
Primary
Concomitant
Joint Swelling Hospitalization 8/1/2011 44 Female 289 lb 8/30/2011 Consumer United States
Primary
Concomitant
Joint Stiffness Hospitalization 6/1/2011 63 Female 9/16/2011 Consumer United States
Primary
Concomitant
Skin Fibrosis Other Serious 7/1/2009 43 Male 183 lb 10/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/24/2011 55 Female 258 lb 10/12/2011 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2009 43 Male 183 lb 10/18/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization Male 10/12/2011 Physician United States
Primary
Concomitant
Muscular Weakness 2/27/2011 72 Male 174 lb 11/3/2011 Consumer United States
Primary
Secondary
Concomitant
Pyrexia 6/25/2011 58 Male 11/6/2011 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 11/1/2010 60 Female 245 lb 11/16/2011 Consumer United States
Primary
Concomitant
Injection Site Pain Hospitalization 6/1/2011 63 Female 11/21/2011 Consumer United States
Primary
Concomitant
Joint Stiffness Hospitalization 6/1/2011 63 Female 11/22/2011 Consumer United States
Primary
Concomitant
Skin Fibrosis Other Serious 7/1/2009 43 Male 183 lb 12/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization Female 269 lb 12/21/2011 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 1/1/2011 45 Male 287 lb 1/13/2012 Consumer United States
Primary
Secondary
Concomitant
Urticaria 1/1/2009 63 Female 255 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Reaction 4/1/2011 27 Female 1/28/2012 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 4/12/2011 42 Female 250 lb 1/28/2012 Consumer United States
Primary
Concomitant
Device Malfunction 67 Female 1/28/2012 Consumer United States
Primary
Concomitant
Nausea 6/16/2011 63 Female 1/28/2012 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 6/26/2011 45 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema Other Serious 1/1/2011 71 Female 217 lb 1/29/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization 5/1/2011 57 Male 175 lb 1/29/2012 Physician United States
Primary
Secondary
Concomitant
Sciatica 6/1/2011 60 Female 1/28/2012 Consumer United States
Primary
Concomitant
Insomnia 1/1/2009 51 Female 237 lb 1/28/2012 Consumer United States
Primary
Concomitant
Death Death Female 303 lb 2/9/2012 Physician United States
Primary
Concomitant
Cardiac Stress Test Abnormal Other Serious 11/1/2010 60 Female 245 lb 2/14/2012 Physician
Primary
Concomitant
Blood Glucose Decreased Hospitalization 6/15/2011 64 Female 2/27/2012 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 6/15/2011 64 Female 3/1/2012 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/1/2009 43 Male 183 lb 3/2/2012 Consumer United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 2/25/2012 33 Female 188 lb 3/1/2012 United States
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 1/1/2011 34 Male 255 lb 4/13/2012 Consumer United States
Primary
Concomitant
Parotitis Hospitalization 3/8/2012 51 Female 225 lb 4/13/2012 Physician Australia
Primary
Concomitant
X-ray Abnormal Death Male 215 lb 5/9/2012 Consumer United States
Primary
Concomitant
Perineal Cyst Other Serious 8/1/2008 61 Male 264 lb 6/1/2012 Consumer United States
Primary
Secondary
Diarrhoea Hospitalization 8/1/2008 61 Male 264 lb 6/12/2012 Consumer United States
Primary
Secondary
Contusion 6/2/2011 54 Female 7/9/2012 Physician United States
Primary
Concomitant
Decreased Immune Responsiveness Hospitalization 8/1/2008 61 Male 264 lb 8/2/2012 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 8/2006 Female 186 lb 9/6/2012 Consumer Us
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 2006 Male 250 lb 8/28/2012 Consumer Us
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 8/2008 Male 264 lb 11/15/2012 Consumer Us
Primary
Secondary
Concomitant
Latent Tuberculosis 7/17/2012 56 Female 177 lb 12/4/2012 Other Health Professional Us
Primary
Concomitant
Sinusitis 12/2/2011 53 Female 10/24/2012 Other Health Professional Us
Primary
Concomitant
Upper Respiratory Tract Infection 54 Female 183 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Paraesthesia 7/1/2012 58 Female 175 lb 10/26/2012 Physician Us
Primary
Concomitant
Rash Pruritic Female 11/7/2012 Physician Us
Primary
Concomitant
Dyspnoea 11/15/2011 48 Female 11/7/2012 Physician Us
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/2012 Female 210 lb 11/21/2012 Consumer Us
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/13/2011 33 Female 265 lb 11/23/2012 Consumer Us
Primary
Secondary
Concomitant
Therapeutic Response Decreased 8/2012 45 Male 256 lb 12/4/2012 Other Health Professional Us
Primary
Concomitant
Bunion Other Serious 61 Female 164 lb 2/6/2013 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/18/2009 24 Female 122 lb 12/14/2012 Consumer Us
Primary
Secondary
Concomitant
Death Death 10/19/2012 65 Female 1/28/2013 Physician Us
Primary
Concomitant
Psoriasis 12/26/2011 59 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain 3/2/2012 51 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Temperature Intolerance Female 139 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Urticaria 2/21/2012 50 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Psoriatic Arthropathy 2/25/2012 63 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Psoriatic Arthropathy 53 Male 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain 4/2012 49 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Swelling 3/15/2012 39 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Drug Effect Decreased 12/26/2011 60 Male 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Thyroid Disorder 2011 62 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Toothache 7/2012 56 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity 51 Female 155 lb 2/15/2013 Consumer Us
Primary
Concomitant
Unevaluable Event 10/11/2012 51 Female 235 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Drug Ineffective 2/2012 Female 185 lb 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Wheezing 58 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Paraesthesia 76 Female 143 lb 10/29/2012 Physician Us
Primary
Concomitant

Drug Data