Methotrexate combined with Sulfasalazine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Jaundice Hospitalization 11/7/2005 Female 1/4/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/15/2005 Female 1/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Von Willebrand's Factor Multimers Abnormal Other Serious 8/1/2005 57 Female 150 lb 12/30/2005 Argentina
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2003 44 Male 1/12/2006 Norway
Primary
Concomitant
Pregnancy Other Serious 12/8/2005 32 Female 1/12/2006 Other Health Professional Mexico
Primary
Concomitant
Lymphoma Death 68 Male 1/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 1/18/2006 Austria
Primary
Concomitant
Peripheral Artery Aneurysm Death 10/22/2005 Male 1/18/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2005 Female 1/18/2006 United Kingdom
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 9/15/2005 Male 245 lb 1/19/2006 Physician United Kingdom
Primary
Concomitant
Foot Fracture Other Serious 1/9/2006 Female 265 lb 1/23/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 1/24/2006 Austria
Primary
Concomitant
Metastatic Neoplasm Death 1/30/2004 Female 152 lb 1/26/2006 United Kingdom
Primary
Concomitant
Peripheral Embolism Other Serious 12/15/2004 Female 1/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2006 Female 155 lb 2/1/2006 Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 10/26/2005 Female 97 lb 2/6/2006 Physician United Kingdom
Primary
Concomitant
Urinary Retention Death 10/21/2005 Male 192 lb 2/3/2006 United Kingdom
Primary
Concomitant
Knee Arthroplasty Hospitalization 7/26/2004 Male 298 lb 2/6/2006 Germany
Primary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 Male 203 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 2/9/2006 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 1/17/2003 64 Female 2/10/2006 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 10/12/2005 Female 2/10/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 2/10/2006 Austria
Primary
Concomitant
Blood Pressure Increased Hospitalization 1/3/2006 Female 222 lb 2/14/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 Male 2/17/2006 Consumer Sweden
Primary
Secondary
Concomitant
Peridiverticular Abscess Hospitalization 1/1/2006 Female 155 lb 2/17/2006 Physician Canada
Primary
Concomitant
Myocardial Infarction Death 10/15/2005 Male 198 lb 2/20/2006 Consumer United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 6/15/2005 Male 181 lb 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/24/2005 79 Female 2/14/2006 Physician France
Primary
Secondary
Concomitant
Myalgia Other Serious Male 175 lb 2/16/2006 United States
Primary
Concomitant
Diarrhoea Other Serious 11/1/2005 Male 192 lb 2/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Other Serious 1/19/2001 69 Female 115 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Jaundice Hospitalization 11/7/2005 Female 2/24/2006 Physician Japan
Primary
Secondary
Neutropenia Other Serious 11/15/2005 Female 2/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/1999 37 Female 148 lb 2/28/2006 Physician United States
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Coronary Arterial Stent Insertion Other Serious 11/30/2005 Female 167 lb 2/28/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 1/31/2006 50 Female 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious Male 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/11/2001 69 Female 115 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 3/6/2006 Other Health Professional Austria
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 3/7/2006 Consumer Canada
Primary
Concomitant
Respiratory Failure Death 46 Female 3/4/2006 Turkey
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/31/2006 Female 130 lb 3/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2002 Female 226 lb 3/13/2006 Physician United States
Primary
Concomitant
B-cell Lymphoma Other Serious 9/30/2005 Female 148 lb 3/15/2006 Physician United States
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/25/2006 Male 311 lb 3/16/2006 Physician Canada
Primary
Concomitant
Pain In Extremity Other Serious 1/9/2006 Female 265 lb 3/20/2006 Physician United States
Primary
Concomitant
Breast Cancer Life Threatening Female 176 lb 3/21/2006 Physician Netherlands
Primary
Concomitant
Sepsis Hospitalization 2/1/2006 Female 66 lb 3/22/2006 Physician Korea, Republic Of
Primary
Concomitant
Respiratory Failure Other Serious 19 Female 121 lb 3/22/2006 Other Health Professional Austria
Primary
Concomitant
Carcinoid Tumour Of The Caecum Other Serious 10/11/2005 Female 161 lb 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2001 41 Female 150 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 3/27/2006 Physician Canada
Primary
Concomitant
Respiratory Failure Hospitalization 1/31/2006 Female 130 lb 3/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Optic Neuritis Retrobulbar Hospitalization 3/21/2005 32 Female 207 lb 3/27/2006 Other Health Professional France
Primary
Concomitant
Myocardial Infarction Death 10/15/2005 Male 198 lb 4/3/2006 Consumer United Kingdom
Primary
Concomitant
Nasal Septum Deviation Hospitalization 10/1/2002 52 Male 218 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Oedema Peripheral Life Threatening 8/20/2004 Female 254 lb 4/6/2006 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Death 10/15/2005 Male 198 lb 4/6/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/25/2005 Female 119 lb 4/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/15/2005 Male 245 lb 4/11/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 12/26/2005 Female 4/11/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 4/12/2006 Physician United States
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 2/20/2006 Female 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stress Required Intervention 7/10/2000 62 Female 144 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Pneumococcal Sepsis Death 1/24/2006 Female 126 lb 4/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Bronchial Carcinoma Life Threatening 4/11/2005 Female 4/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 10/29/2003 65 Female 134 lb 4/21/2006 Lawyer United States
Primary
Concomitant
Osteomyelitis Hospitalization 10/15/2005 Male 176 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 1/17/2006 Female 126 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 6/1/2005 Female 139 lb 4/25/2006 Physician United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 55 Female 4/14/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Sudden Death Death 6/15/2004 53 Male 4/27/2006 Norway
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/30/2005 85 Male 4/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 1/3/2006 Female 222 lb 5/3/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/31/2006 Female 130 lb 5/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 58 Male 5/5/2006 Physician France
Primary
Concomitant
Encephalitis Herpes Life Threatening 12/1/2005 Female 5/9/2006 Physician Canada
Primary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/5/2006 53 Female 5/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 10/1/2005 Female 172 lb 5/11/2006 Physician United States
Primary
Concomitant
Death Life Threatening 3/12/2006 Male 117 lb 5/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/11/2001 69 Female 115 lb 5/18/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 3/30/2006 Male 119 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 2/15/2004 Female 112 lb 5/23/2006 Consumer United Kingdom
Primary
Concomitant
Infusion Related Reaction Hospitalization 1/3/2006 Female 338 lb 6/2/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/10/2004 Female 90 lb 6/2/2006 France
Primary
Concomitant
Miller Fisher Syndrome Other Serious 56 Male 6/5/2006 Physician United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 1/1/2006 Female 130 lb 6/6/2006 Other Health Professional United States
Primary
Concomitant
Tuberculous Pleurisy Hospitalization 5/18/2006 Male 137 lb 6/6/2006 Physician Colombia
Primary
Concomitant
Calculus Bladder Hospitalization 6/1/2005 Male 134 lb 6/8/2006 United Kingdom
Primary
Concomitant
Sepsis Death Female 6/9/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 12/11/2005 Female 212 lb 6/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 10/15/2005 Male 176 lb 6/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Viral Infection Other Serious 1/1/2002 Female 104 lb 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/2005 65 Female 279 lb 6/14/2006 Physician Canada
Primary
Concomitant
Sleep Disorder Disability 4/6/2006 65 Female 97 lb 6/7/2006 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2005 61 Female 6/20/2006 Physician Japan
Primary
Concomitant
Uterine Leiomyoma Required Intervention 7/10/2000 62 Female 144 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 11/7/2005 Female 123 lb 6/23/2006 Physician Japan
Primary
Secondary
Migraine Other Serious 3/10/2006 Female 155 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malabsorption Hospitalization 4/7/2006 Female 128 lb 6/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death 5/24/2006 Female 152 lb 6/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/10/2006 Male 218 lb 6/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Knee Arthroplasty Hospitalization 3/21/2006 Female 6/30/2006 Consumer United States
Primary
Concomitant
Pneumonitis Chemical Death 4/16/2006 Male 159 lb 7/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening Male 117 lb 7/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Bronchopneumonia Death 3/16/2006 Female 123 lb 7/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/30/2005 Female 148 lb 7/17/2006 Physician United States
Primary
Concomitant
Lymphopenia Hospitalization 1/1/2006 33 Female 7/12/2006 Other Health Professional Austria
Primary
Concomitant
Myocardial Infarction Other Serious 4/19/2006 Female 126 lb 7/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Miller Fisher Syndrome Other Serious 11/11/2003 Male 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/1/2004 46 Female 7/14/2006 Korea, Democratic People's Republic Of
Primary
Concomitant
Pancreatic Disorder Other Serious 2/6/2006 Female 151 lb 7/21/2006 Physician United States
Primary
Concomitant
Urticaria Life Threatening 2/1/2006 Female 196 lb 7/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/31/2006 Female 130 lb 7/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 4/17/2006 59 Male 265 lb 7/28/2006 Physician France
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 7/28/2006 Physician Belgium
Primary
Concomitant
B-cell Lymphoma Stage Ii Other Serious 4/13/2006 68 Male 132 lb 7/31/2006 Other Health Professional Germany
Primary
Concomitant
Tuberculosis Other Serious 2/14/2006 Female 117 lb 7/31/2006 Physician Italy
Primary
Concomitant
Septic Shock Hospitalization 2/4/2006 Male 114 lb 8/1/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Synovitis Other Serious 10/1/1999 77 Female 7/13/2006
Primary
Secondary
Viral Infection Other Serious 1/1/2002 Female 104 lb 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Tendonitis Other Serious 12/2/2004 24 Female 8/2/2006 Physician France
Primary
Concomitant
Pancreatic Disorder Other Serious 2/6/2006 Female 151 lb 8/2/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 1/28/2002 Female 145 lb 8/2/2006 Physician United States
Primary
Concomitant
Pneumococcal Sepsis Death 1/24/2006 Female 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/17/2006 Female 126 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 10/15/2005 Male 198 lb 8/2/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 12/26/2005 Female 8/3/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Depression Death 4/17/2006 58 Male 265 lb 8/9/2006 Physician France
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/24/2004 60 Female 8/11/2006 Other Health Professional France
Primary
Concomitant
Basal Cell Carcinoma Other Serious 7/25/2006 Female 226 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/15/2006 Female 143 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lupus-like Syndrome Other Serious 7/3/2006 23 Female 154 lb 8/14/2006 Physician Australia
Primary
Concomitant
Proctitis Ulcerative Other Serious 8/15/2005 56 Female 8/14/2006 Physician Germany
Primary
Secondary
Concomitant
Femoral Neck Fracture Other Serious 2/10/2006 Female 139 lb 8/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Other Serious 4/22/2006 Male 156 lb 8/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 79 Female 8/17/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 3/19/2005 Female 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Injury Asphyxiation Life Threatening 4/17/2006 58 Male 265 lb 8/11/2006 Physician France
Primary
Secondary
Concomitant
Lymphoedema Hospitalization 60 Female 8/18/2006 Physician Germany
Primary
Secondary
Uveitis Hospitalization 10/15/2005 45 Female 8/17/2006 Physician Germany
Primary
Concomitant
Lupus-like Syndrome Other Serious 7/3/2006 23 Female 154 lb 8/21/2006 Physician Australia
Primary
Concomitant
Injection Site Cellulitis Other Serious 2/23/2006 Male 311 lb 8/21/2006 Physician Canada
Primary
Concomitant
Osteoporotic Fracture Other Serious 4/1/2006 Male 168 lb 8/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death 5/24/2006 Female 152 lb 6/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data